FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6982, 246 aa 1>>>pF1KB6982 246 - 246 aa - 246 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2355+/-0.000948; mu= 14.1382+/- 0.056 mean_var=57.1438+/-11.325, 0's: 0 Z-trim(103.5): 27 B-trim: 0 in 0/49 Lambda= 0.169664 statistics sampled from 7436 (7461) to 7436 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.229), width: 16 Scan time: 1.580 The best scores are: opt bits E(32554) CCDS9655.1 PSMA6 gene_id:5687|Hs108|chr14 ( 246) 1619 404.6 3.1e-113 CCDS61437.1 PSMA6 gene_id:5687|Hs108|chr14 ( 227) 1452 363.7 5.9e-101 CCDS61438.1 PSMA6 gene_id:5687|Hs108|chr14 ( 167) 1108 279.5 9.9e-76 CCDS5467.1 PSMA2 gene_id:5683|Hs108|chr7 ( 234) 465 122.1 3.2e-28 CCDS10303.1 PSMA4 gene_id:5685|Hs108|chr15 ( 261) 442 116.5 1.7e-26 CCDS13489.1 PSMA7 gene_id:5688|Hs108|chr20 ( 248) 439 115.8 2.8e-26 CCDS45842.1 PSMA8 gene_id:143471|Hs108|chr18 ( 250) 413 109.4 2.3e-24 CCDS799.1 PSMA5 gene_id:5686|Hs108|chr1 ( 241) 403 107.0 1.2e-23 CCDS32808.1 PSMA8 gene_id:143471|Hs108|chr18 ( 256) 398 105.8 3e-23 CCDS9731.1 PSMA3 gene_id:5684|Hs108|chr14 ( 255) 391 104.0 9.8e-23 CCDS45113.1 PSMA3 gene_id:5684|Hs108|chr14 ( 248) 369 98.7 4e-21 CCDS7816.1 PSMA1 gene_id:5682|Hs108|chr11 ( 263) 363 97.2 1.2e-20 CCDS31431.1 PSMA1 gene_id:5682|Hs108|chr11 ( 269) 363 97.2 1.2e-20 CCDS77169.1 PSMA8 gene_id:143471|Hs108|chr18 ( 224) 299 81.5 5.2e-16 CCDS45319.1 PSMA4 gene_id:5685|Hs108|chr15 ( 190) 281 77.1 9.6e-15 CCDS55619.1 PSMA5 gene_id:5686|Hs108|chr1 ( 183) 263 72.7 2e-13 CCDS45843.1 PSMA8 gene_id:143471|Hs108|chr18 ( 212) 241 67.3 9.4e-12 >>CCDS9655.1 PSMA6 gene_id:5687|Hs108|chr14 (246 aa) initn: 1619 init1: 1619 opt: 1619 Z-score: 2146.4 bits: 404.6 E(32554): 3.1e-113 Smith-Waterman score: 1619; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV 190 200 210 220 230 240 pF1KB6 ALAERD :::::: CCDS96 ALAERD >>CCDS61437.1 PSMA6 gene_id:5687|Hs108|chr14 (227 aa) initn: 1452 init1: 1452 opt: 1452 Z-score: 1926.0 bits: 363.7 E(32554): 5.9e-101 Smith-Waterman score: 1452; 100.0% identity (100.0% similar) in 221 aa overlap (26-246:7-227) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL ::::::::::::::::::::::::::::::::::: CCDS61 MAGLRREYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL 10 20 30 40 70 80 90 100 110 120 pF1KB6 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV 170 180 190 200 210 220 pF1KB6 ALAERD :::::: CCDS61 ALAERD >>CCDS61438.1 PSMA6 gene_id:5687|Hs108|chr14 (167 aa) initn: 1108 init1: 1108 opt: 1108 Z-score: 1473.1 bits: 279.5 E(32554): 9.9e-76 Smith-Waterman score: 1108; 100.0% identity (100.0% similar) in 167 aa overlap (80-246:1-167) 50 60 70 80 90 100 pF1KB6 IVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEI :::::::::::::::::::::::::::::: CCDS61 MTGMTADSRSQVQRARYEAANWKYKYGYEI 10 20 30 110 120 130 140 150 160 pF1KB6 PVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 PVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAG 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 VKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRI 100 110 120 130 140 150 230 240 pF1KB6 LTEAEIDAHLVALAERD ::::::::::::::::: CCDS61 LTEAEIDAHLVALAERD 160 >>CCDS5467.1 PSMA2 gene_id:5683|Hs108|chr7 (234 aa) initn: 423 init1: 235 opt: 465 Z-score: 620.1 bits: 122.1 E(32554): 3.2e-28 Smith-Waterman score: 465; 35.6% identity (67.4% similar) in 236 aa overlap (8-243:5-234) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL :.. .: ::: :.: :.:::. :. :: ::.... . .:..:.:: . : CCDS54 MAERGYSFSLTTFSPSGKLVQIEYALAAVA-GGAPSVGIKAANGVVLATEKKQKSIL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD : .: .. ::..:: :..:: : : :.::: : .. : ::. .: .:.:. CCDS54 YDERSVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVAS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE . : :::.. .::.: ... : .: . : ... ::.: : ..:::: : . ... .::: CCDS54 VMQEYTQSGGVRPFGVSLLICGWNEGR-PYLFQSDPSGAYFAWKATAMGKNYVNGKTFLE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV :. .. : .:....::: :. . .. ..::::. .. :: :: .:. .:. CCDS54 KRYNE--DLELEDAIHTAILTLKESFEGQMTEDNIEVGIC--NEAGFRRLTPTEVKDYLA 180 190 200 210 220 230 pF1KB6 ALAERD :.: CCDS54 AIA >>CCDS10303.1 PSMA4 gene_id:5685|Hs108|chr15 (261 aa) initn: 360 init1: 360 opt: 442 Z-score: 589.0 bits: 116.5 E(32554): 1.7e-26 Smith-Waterman score: 442; 32.8% identity (70.7% similar) in 232 aa overlap (9-236:5-234) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL .: . :::::::::::::::..::...: : ... ..: ........ :: CCDS10 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAG-TCLGILANDGVLLAAERRNIHKL 10 20 30 40 50 70 80 90 100 110 pF1KB6 LDSSTVTH-LFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIA :: .. ..:..:...: ..:.:.:. ... : : . .: :: ..: . CCDS10 LDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 DISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFL ::.:.::: . ::.: .. :: :.. : :.:. ::.: : :.::: : ... ..:.: CCDS10 DIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSML 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 EKKVKKKFDWTFEQTVETAITCLSTVLSID-FKPSEIEVGVVTVENPK--FRILTEAEID .. :. . :..... :: :. ..... .. ..:....: :: : .:.: . :.. CCDS10 KQDYKEG-EMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVE 180 190 200 210 220 230 240 pF1KB6 AHLVALAERD CCDS10 QLIKKHEEEEAKAEREKKEKEQKEKDK 240 250 260 >>CCDS13489.1 PSMA7 gene_id:5688|Hs108|chr20 (248 aa) initn: 308 init1: 308 opt: 439 Z-score: 585.3 bits: 115.8 E(32554): 2.8e-26 Smith-Waterman score: 439; 34.5% identity (66.0% similar) in 238 aa overlap (9-246:3-235) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL .:: ::.:::.:.:.::::: .:...:. :.:.:::.: .:. ..:: :: CCDS13 MSYDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGRDIVVLGVEKKSVAKL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD : :: .. . .:. ...:.:::.: ..::: : . . . :... . ::. CCDS13 QDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIAS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE ..: :::. ::.: ...:.: . :..:. ::.: : ..::.: : ::: CCDS13 LKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV :. . : . :.. .: : :.. : .::..:. .. ...::. ::. . : CCDS13 KNYTDEAIETDDLTIKLVIKALLEVVQSGGK--NIELAVMR-RDQSLKILNPEEIEKY-V 180 190 200 210 220 pF1KB6 ALAERD : :.. CCDS13 AEIEKEKEENEKKKQKKAS 230 240 >>CCDS45842.1 PSMA8 gene_id:143471|Hs108|chr18 (250 aa) initn: 388 init1: 286 opt: 413 Z-score: 550.9 bits: 109.4 E(32554): 2.3e-24 Smith-Waterman score: 413; 30.8% identity (65.8% similar) in 234 aa overlap (9-242:5-234) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL .:: ::.:::.:.:.::::: .:...:. :.:..:: . .:. ..:: :: CCDS45 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRGTNIVVLGVEKKSVAKL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD : :: .. . ... ...:.:::.: ..::: : . : . :... . :: CCDS45 QDERTVRKICALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIAT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE ..: :::. ::.: ...:.:.. ..:. ::.: : ..::.: : . ::: CCDS45 LKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV :. . . .... :: : :.. : .::.... ..: ..... :.. ... CCDS45 KNYTEDAIASDSEAIKLAIKALLEVVQSGGK--NIELAIIRRNQP-LKMFSAKEVELYVT 180 190 200 210 220 230 pF1KB6 ALAERD . CCDS45 EIEKEKEEAEKKKSKKSV 240 250 >>CCDS799.1 PSMA5 gene_id:5686|Hs108|chr1 (241 aa) initn: 281 init1: 121 opt: 403 Z-score: 537.9 bits: 107.0 E(32554): 1.2e-23 Smith-Waterman score: 403; 27.5% identity (70.0% similar) in 233 aa overlap (9-236:8-235) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL .:: .. :::::::.:::::..::. :. :..... .. . ....:.. . : CCDS79 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGS-TAIGIQTSEGVCLAVEKRITSPL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD .. :.. .. .: .:::.:.:. ::... ...:: :. : . :. . :. . . ... CCDS79 MEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSN 60 70 80 90 100 110 130 140 150 160 170 pF1KB6 IS-QVYTQNAE----MRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTES .. : ..:. ::.: ... :.:: .:::... ::.: . : : : . . CCDS79 LALQFGEEDADPGAMSRPFGVALLFGGVDE-KGPQLFHMDPSGTFVQCDARAIGSASEGA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 TSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEI : :.. .:.. :......... :. :. .. ..::...: . .:...:. :. CCDS79 QSSLQEVYHKSM--TLKEAIKSSLIILKQVMEEKLNATNIELATVQ-PGQNFHMFTKEEL 180 190 200 210 220 230 240 pF1KB6 DAHLVALAERD . CCDS79 EEVIKDI 240 >>CCDS32808.1 PSMA8 gene_id:143471|Hs108|chr18 (256 aa) initn: 362 init1: 219 opt: 398 Z-score: 530.9 bits: 105.8 E(32554): 3e-23 Smith-Waterman score: 398; 31.1% identity (64.3% similar) in 241 aa overlap (9-242:5-240) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL .:: ::.:::.:.:.::::: .:...:. :.:..:: . .:. ..:: :: CCDS32 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGIRGTNIVVLGVEKKSVAKL 10 20 30 40 50 70 80 90 100 110 pF1KB6 LDSSTVTHLFKITENIGC----VMT---GMTADSRSQVQRARYEAANWKYKYGYEIPVDM : :: .. . ... : :.: :.:::.: ..::: : . : . :.. CCDS32 QDERTVRKICALDDHV-CMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQT . . :: ..: :::. ::.: ...:.:.. ..:. ::.: : ..::.: : . CCDS32 ITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 ESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEA ::::. . . .... :: : :.. : .::.... ..: ..... CCDS32 TVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQSGGK--NIELAIIRRNQP-LKMFSAK 180 190 200 210 220 230 240 pF1KB6 EIDAHLVALAERD :.. ... . CCDS32 EVELYVTEIEKEKEEAEKKKSKKSV 240 250 >>CCDS9731.1 PSMA3 gene_id:5684|Hs108|chr14 (255 aa) initn: 373 init1: 296 opt: 391 Z-score: 521.6 bits: 104.0 E(32554): 9.8e-23 Smith-Waterman score: 391; 35.1% identity (71.3% similar) in 174 aa overlap (8-181:7-179) 10 20 30 40 50 60 pF1KB6 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL :.: . :::.::..:::::.::..... :....: :: .:. ..: : .:: CCDS97 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSS-TAIGIRCKDGVVFGVEKLVLSKL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD . .. .::.. ...: ...:. ::.:: .. :: ::.:.. ..::.::. : :.: CCDS97 YEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAM 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE ..:: . .::.:: ..: . . ..: :.: ::.: :. . : : . . . .: CCDS97 YVHAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV : CCDS97 KLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEK 180 190 200 210 220 230 246 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 10:44:17 2016 done: Fri Nov 4 10:44:18 2016 Total Scan time: 1.580 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]