FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6988, 248 aa
1>>>pF1KB6988 248 - 248 aa - 248 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7902+/-0.000353; mu= 6.9973+/- 0.022
mean_var=230.6587+/-45.436, 0's: 0 Z-trim(122.7): 407 B-trim: 1453 in 1/55
Lambda= 0.084448
statistics sampled from 40856 (41374) to 40856 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.485), width: 16
Scan time: 8.020
The best scores are: opt bits E(85289)
XP_011538118 (OMIM: 154545,614372) PREDICTED: mann ( 248) 1697 218.4 9.1e-57
NP_000233 (OMIM: 154545,614372) mannose-binding pr ( 248) 1697 218.4 9.1e-57
XP_006717924 (OMIM: 154545,614372) PREDICTED: mann ( 248) 1697 218.4 9.1e-57
XP_011538390 (OMIM: 178635) PREDICTED: pulmonary s ( 336) 562 80.3 4.7e-15
NP_003010 (OMIM: 178635) pulmonary surfactant-asso ( 375) 562 80.4 5.1e-15
XP_011538389 (OMIM: 178635) PREDICTED: pulmonary s ( 375) 562 80.4 5.1e-15
XP_005270119 (OMIM: 178500,178630) PREDICTED: pulm ( 248) 518 74.8 1.6e-13
NP_001158116 (OMIM: 178500,178630) pulmonary surfa ( 248) 518 74.8 1.6e-13
NP_005402 (OMIM: 178500,178630) pulmonary surfacta ( 248) 518 74.8 1.6e-13
NP_001158119 (OMIM: 178500,178630) pulmonary surfa ( 248) 518 74.8 1.6e-13
XP_006718016 (OMIM: 178500,178630) PREDICTED: pulm ( 263) 518 74.8 1.6e-13
NP_001087239 (OMIM: 178500,178630) pulmonary surfa ( 263) 518 74.8 1.6e-13
NP_001092138 (OMIM: 178500,178642) pulmonary surfa ( 248) 513 74.2 2.4e-13
XP_011538427 (OMIM: 178500,178642) PREDICTED: pulm ( 248) 513 74.2 2.4e-13
XP_011538426 (OMIM: 178500,178642) PREDICTED: pulm ( 248) 513 74.2 2.4e-13
XP_016872097 (OMIM: 178500,178642) PREDICTED: pulm ( 248) 513 74.2 2.4e-13
XP_005270189 (OMIM: 178500,178642) PREDICTED: pulm ( 248) 513 74.2 2.4e-13
NP_001307742 (OMIM: 178500,178642) pulmonary surfa ( 248) 513 74.2 2.4e-13
NP_001307743 (OMIM: 178500,178642) pulmonary surfa ( 258) 513 74.2 2.5e-13
XP_005270185 (OMIM: 178500,178642) PREDICTED: pulm ( 265) 513 74.2 2.5e-13
NP_001242912 (OMIM: 265050,612502) collectin-11 is ( 247) 389 59.1 8.5e-09
XP_006711960 (OMIM: 265050,612502) PREDICTED: coll ( 261) 389 59.1 8.8e-09
NP_001242915 (OMIM: 265050,612502) collectin-11 is ( 245) 385 58.6 1.2e-08
NP_076932 (OMIM: 265050,612502) collectin-11 isofo ( 271) 385 58.6 1.3e-08
NP_001242914 (OMIM: 265050,612502) collectin-11 is ( 285) 385 58.7 1.3e-08
NP_001158118 (OMIM: 178500,178630) pulmonary surfa ( 199) 381 58.0 1.5e-08
NP_001158117 (OMIM: 178500,178630) pulmonary surfa ( 214) 381 58.0 1.5e-08
NP_001242917 (OMIM: 265050,612502) collectin-11 is ( 221) 373 57.1 3.1e-08
NP_001242911 (OMIM: 265050,612502) collectin-11 is ( 247) 373 57.1 3.3e-08
XP_005263910 (OMIM: 265050,612502) PREDICTED: coll ( 261) 373 57.2 3.4e-08
NP_006429 (OMIM: 607620) collectin-10 isoform 1 pr ( 277) 367 56.5 5.9e-08
NP_954705 (OMIM: 265050,612502) collectin-11 isofo ( 268) 366 56.3 6.3e-08
NP_001242916 (OMIM: 265050,612502) collectin-11 is ( 221) 357 55.1 1.2e-07
NP_001311024 (OMIM: 607620) collectin-10 isoform 2 ( 208) 353 54.6 1.6e-07
XP_005250813 (OMIM: 607620) PREDICTED: collectin-1 ( 208) 353 54.6 1.6e-07
NP_001242913 (OMIM: 265050,612502) collectin-11 is ( 223) 331 52.0 1.1e-06
NP_001242918 (OMIM: 265050,612502) collectin-11 is ( 197) 309 49.2 6.3e-06
NP_005743 (OMIM: 613588) C-type lectin domain fami ( 206) 266 44.0 0.00025
NP_001231684 (OMIM: 613588) C-type lectin domain f ( 145) 261 43.2 0.0003
XP_005251116 (OMIM: 120324) PREDICTED: collagen al (1780) 253 43.5 0.003
XP_006716714 (OMIM: 120324) PREDICTED: collagen al (1796) 253 43.5 0.0031
NP_066933 (OMIM: 120324) collagen alpha-1(XIV) cha (1796) 253 43.5 0.0031
XP_016869298 (OMIM: 120324) PREDICTED: collagen al (1796) 253 43.5 0.0031
NP_001295323 (OMIM: 187520) tetranectin isoform 2 ( 160) 233 39.9 0.0034
XP_016862605 (OMIM: 187520) PREDICTED: tetranectin ( 169) 233 39.9 0.0035
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 251 43.2 0.0035
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 251 43.3 0.0037
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 251 43.3 0.0037
NP_003269 (OMIM: 187520) tetranectin isoform 1prec ( 202) 233 40.0 0.0039
XP_016862606 (OMIM: 187520) PREDICTED: tetranectin ( 209) 233 40.0 0.004
>>XP_011538118 (OMIM: 154545,614372) PREDICTED: mannose- (248 aa)
initn: 1697 init1: 1697 opt: 1697 Z-score: 1140.1 bits: 218.4 E(85289): 9.1e-57
Smith-Waterman score: 1697; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)
10 20 30 40 50 60
pF1KB6 MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSH
190 200 210 220 230 240
pF1KB6 LAVCEFPI
::::::::
XP_011 LAVCEFPI
>>NP_000233 (OMIM: 154545,614372) mannose-binding protei (248 aa)
initn: 1697 init1: 1697 opt: 1697 Z-score: 1140.1 bits: 218.4 E(85289): 9.1e-57
Smith-Waterman score: 1697; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)
10 20 30 40 50 60
pF1KB6 MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSH
190 200 210 220 230 240
pF1KB6 LAVCEFPI
::::::::
NP_000 LAVCEFPI
>>XP_006717924 (OMIM: 154545,614372) PREDICTED: mannose- (248 aa)
initn: 1697 init1: 1697 opt: 1697 Z-score: 1140.1 bits: 218.4 E(85289): 9.1e-57
Smith-Waterman score: 1697; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)
10 20 30 40 50 60
pF1KB6 MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSH
190 200 210 220 230 240
pF1KB6 LAVCEFPI
::::::::
XP_006 LAVCEFPI
>>XP_011538390 (OMIM: 178635) PREDICTED: pulmonary surfa (336 aa)
initn: 623 init1: 274 opt: 562 Z-score: 391.2 bits: 80.3 E(85289): 4.7e-15
Smith-Waterman score: 599; 43.6% identity (67.4% similar) in 227 aa overlap (40-246:110-336)
10 20 30 40 50 60
pF1KB6 LLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQ----G
.::..: : : : :::.: ::. :
XP_011 QAGPVGPKGDNGSVGEPGPKGDTGPSGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPG
80 90 100 110 120 130
70 80 90 100 110
pF1KB6 LRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPG-KSPDGDSSL--AASERKA--------
: : : .:: :.:: : :: ::.:: :: :. :.:.: .:: :.
XP_011 NTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQV
140 150 160 170 180 190
120 130 140 150 160 170
pF1KB6 --LQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENG
::. ... :: : :..::.:.: : : . : ... ::.. ...:.::.::::.
XP_011 QHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENA
200 210 220 230 240 250
180 190 200 210 220
pF1KB6 AIQNLI---KEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNG
:.:.:. .: :::..:: ::::.:. ::. :.:.:: ::::. :..:::: .. ::
XP_011 ALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNG
260 270 280 290 300 310
230 240
pF1KB6 QWNDVPCSTSHLAVCEFPI
.::: :. ..:.::::
XP_011 KWNDRACGEKRLVVCEF
320 330
>>NP_003010 (OMIM: 178635) pulmonary surfactant-associat (375 aa)
initn: 542 init1: 274 opt: 562 Z-score: 390.7 bits: 80.4 E(85289): 5.1e-15
Smith-Waterman score: 599; 43.6% identity (67.4% similar) in 227 aa overlap (40-246:149-375)
10 20 30 40 50 60
pF1KB6 LLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQ----G
.::..: : : : :::.: ::. :
NP_003 REGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPG
120 130 140 150 160 170
70 80 90 100 110
pF1KB6 LRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPG-KSPDGDSSL--AASERKA--------
: : : .:: :.:: : :: ::.:: :: :. :.:.: .:: :.
NP_003 NTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQV
180 190 200 210 220 230
120 130 140 150 160 170
pF1KB6 --LQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENG
::. ... :: : :..::.:.: : : . : ... ::.. ...:.::.::::.
NP_003 QHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENA
240 250 260 270 280 290
180 190 200 210 220
pF1KB6 AIQNLI---KEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNG
:.:.:. .: :::..:: ::::.:. ::. :.:.:: ::::. :..:::: .. ::
NP_003 ALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNG
300 310 320 330 340 350
230 240
pF1KB6 QWNDVPCSTSHLAVCEFPI
.::: :. ..:.::::
NP_003 KWNDRACGEKRLVVCEF
360 370
>>XP_011538389 (OMIM: 178635) PREDICTED: pulmonary surfa (375 aa)
initn: 542 init1: 274 opt: 562 Z-score: 390.7 bits: 80.4 E(85289): 5.1e-15
Smith-Waterman score: 599; 43.6% identity (67.4% similar) in 227 aa overlap (40-246:149-375)
10 20 30 40 50 60
pF1KB6 LLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQ----G
.::..: : : : :::.: ::. :
XP_011 REGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPG
120 130 140 150 160 170
70 80 90 100 110
pF1KB6 LRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPG-KSPDGDSSL--AASERKA--------
: : : .:: :.:: : :: ::.:: :: :. :.:.: .:: :.
XP_011 NTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQV
180 190 200 210 220 230
120 130 140 150 160 170
pF1KB6 --LQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENG
::. ... :: : :..::.:.: : : . : ... ::.. ...:.::.::::.
XP_011 QHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENA
240 250 260 270 280 290
180 190 200 210 220
pF1KB6 AIQNLI---KEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNG
:.:.:. .: :::..:: ::::.:. ::. :.:.:: ::::. :..:::: .. ::
XP_011 ALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNG
300 310 320 330 340 350
230 240
pF1KB6 QWNDVPCSTSHLAVCEFPI
.::: :. ..:.::::
XP_011 KWNDRACGEKRLVVCEF
360 370
>>XP_005270119 (OMIM: 178500,178630) PREDICTED: pulmonar (248 aa)
initn: 479 init1: 179 opt: 518 Z-score: 363.8 bits: 74.8 E(85289): 1.6e-13
Smith-Waterman score: 535; 37.5% identity (62.2% similar) in 259 aa overlap (8-246:5-248)
10 20 30 40 50
pF1KB6 MSLFPSLPLLL-LSMVAASYSETVTCEDAQKTC---PAVIACSSPGINGFPGKDGRDGTK
:: : : ..::: ..:: .. .: :.. . .:: .:.::.::::: :
XP_005 MWLCPLALNLILMAAS---GAVCE-VKDVCVGSPGIPG--TPGSHGLPGRDGRDGLK
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GEKGEPGQGLRGLQGPPGKLG-PPGN---PGPSGSPGPKGQKGDPG-KSPDGDSSLAASE
:. : :: .::::.. :::: :: : :: :.::.:: ..: : : :
XP_005 GDPGPPGP-----MGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPG---LPAHL
60 70 80 90 100
120 130 140 150 160
pF1KB6 RKALQTEMARIKKWLTFSLGK--------QVGNKFFLTNGEIMTFEKVKALCVKFQASVA
. ::. . ... . . : ::.: : .::. .::. .. :.. . .:
XP_005 DEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 TPRNAAENGAIQNLIKEE---AFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDE
.::: :: :: ...:. :..:.:. . :.: :. ..:::: .::: . :. :
XP_005 VPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGK-E
170 180 190 200 210 220
230 240
pF1KB6 DCVLLLKNGQWNDVPCSTSHLAVCEFPI
.:: . .::::: : :.:..:::
XP_005 QCVEMYTDGQWNDRNCLYSRLTICEF
230 240
>>NP_001158116 (OMIM: 178500,178630) pulmonary surfactan (248 aa)
initn: 479 init1: 179 opt: 518 Z-score: 363.8 bits: 74.8 E(85289): 1.6e-13
Smith-Waterman score: 535; 37.5% identity (62.2% similar) in 259 aa overlap (8-246:5-248)
10 20 30 40 50
pF1KB6 MSLFPSLPLLL-LSMVAASYSETVTCEDAQKTC---PAVIACSSPGINGFPGKDGRDGTK
:: : : ..::: ..:: .. .: :.. . .:: .:.::.::::: :
NP_001 MWLCPLALNLILMAAS---GAVCE-VKDVCVGSPGIPG--TPGSHGLPGRDGRDGLK
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GEKGEPGQGLRGLQGPPGKLG-PPGN---PGPSGSPGPKGQKGDPG-KSPDGDSSLAASE
:. : :: .::::.. :::: :: : :: :.::.:: ..: : : :
NP_001 GDPGPPGP-----MGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPG---LPAHL
60 70 80 90 100
120 130 140 150 160
pF1KB6 RKALQTEMARIKKWLTFSLGK--------QVGNKFFLTNGEIMTFEKVKALCVKFQASVA
. ::. . ... . . : ::.: : .::. .::. .. :.. . .:
NP_001 DEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 TPRNAAENGAIQNLIKEE---AFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDE
.::: :: :: ...:. :..:.:. . :.: :. ..:::: .::: . :. :
NP_001 VPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGK-E
170 180 190 200 210 220
230 240
pF1KB6 DCVLLLKNGQWNDVPCSTSHLAVCEFPI
.:: . .::::: : :.:..:::
NP_001 QCVEMYTDGQWNDRNCLYSRLTICEF
230 240
>>NP_005402 (OMIM: 178500,178630) pulmonary surfactant-a (248 aa)
initn: 479 init1: 179 opt: 518 Z-score: 363.8 bits: 74.8 E(85289): 1.6e-13
Smith-Waterman score: 535; 37.5% identity (62.2% similar) in 259 aa overlap (8-246:5-248)
10 20 30 40 50
pF1KB6 MSLFPSLPLLL-LSMVAASYSETVTCEDAQKTC---PAVIACSSPGINGFPGKDGRDGTK
:: : : ..::: ..:: .. .: :.. . .:: .:.::.::::: :
NP_005 MWLCPLALNLILMAAS---GAVCE-VKDVCVGSPGIPG--TPGSHGLPGRDGRDGLK
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GEKGEPGQGLRGLQGPPGKLG-PPGN---PGPSGSPGPKGQKGDPG-KSPDGDSSLAASE
:. : :: .::::.. :::: :: : :: :.::.:: ..: : : :
NP_005 GDPGPPGP-----MGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPG---LPAHL
60 70 80 90 100
120 130 140 150 160
pF1KB6 RKALQTEMARIKKWLTFSLGK--------QVGNKFFLTNGEIMTFEKVKALCVKFQASVA
. ::. . ... . . : ::.: : .::. .::. .. :.. . .:
NP_005 DEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 TPRNAAENGAIQNLIKEE---AFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDE
.::: :: :: ...:. :..:.:. . :.: :. ..:::: .::: . :. :
NP_005 VPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGK-E
170 180 190 200 210 220
230 240
pF1KB6 DCVLLLKNGQWNDVPCSTSHLAVCEFPI
.:: . .::::: : :.:..:::
NP_005 QCVEMYTDGQWNDRNCLYSRLTICEF
230 240
>>NP_001158119 (OMIM: 178500,178630) pulmonary surfactan (248 aa)
initn: 479 init1: 179 opt: 518 Z-score: 363.8 bits: 74.8 E(85289): 1.6e-13
Smith-Waterman score: 535; 37.5% identity (62.2% similar) in 259 aa overlap (8-246:5-248)
10 20 30 40 50
pF1KB6 MSLFPSLPLLL-LSMVAASYSETVTCEDAQKTC---PAVIACSSPGINGFPGKDGRDGTK
:: : : ..::: ..:: .. .: :.. . .:: .:.::.::::: :
NP_001 MWLCPLALNLILMAAS---GAVCE-VKDVCVGSPGIPG--TPGSHGLPGRDGRDGLK
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GEKGEPGQGLRGLQGPPGKLG-PPGN---PGPSGSPGPKGQKGDPG-KSPDGDSSLAASE
:. : :: .::::.. :::: :: : :: :.::.:: ..: : : :
NP_001 GDPGPPGP-----MGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPG---LPAHL
60 70 80 90 100
120 130 140 150 160
pF1KB6 RKALQTEMARIKKWLTFSLGK--------QVGNKFFLTNGEIMTFEKVKALCVKFQASVA
. ::. . ... . . : ::.: : .::. .::. .. :.. . .:
NP_001 DEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 TPRNAAENGAIQNLIKEE---AFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDE
.::: :: :: ...:. :..:.:. . :.: :. ..:::: .::: . :. :
NP_001 VPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGK-E
170 180 190 200 210 220
230 240
pF1KB6 DCVLLLKNGQWNDVPCSTSHLAVCEFPI
.:: . .::::: : :.:..:::
NP_001 QCVEMYTDGQWNDRNCLYSRLTICEF
230 240
248 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:46:13 2016 done: Sat Nov 5 17:46:14 2016
Total Scan time: 8.020 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]