Result of FASTA (omim) for
pF1KB7009
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7009, 1072 aa
1>>>pF1KB7009 1072 - 1072 aa - 1072 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6521+/-0.000354; mu= 13.1766+/- 0.022
mean_var=164.7403+/-33.805, 0's: 0 Z-trim(120.7): 41 B-trim: 672 in 1/51
Lambda= 0.099925
statistics sampled from 36149 (36198) to 36149 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.424), width: 16
Scan time: 17.730
The best scores are: opt bits E(85289)
NP_060469 (OMIM: 612487) E3 ubiquitin-protein liga (1072) 7573 1104.3 0
NP_001297261 (OMIM: 612487) E3 ubiquitin-protein l ( 921) 6513 951.5 0
XP_006710421 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 588) 235 46.3 0.00063
NP_001120833 (OMIM: 610872) E3 ubiquitin-protein l ( 587) 234 46.1 0.00069
XP_006710420 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 688) 235 46.3 0.00071
XP_006710419 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 732) 235 46.4 0.00074
NP_699172 (OMIM: 610872) E3 ubiquitin-protein liga ( 732) 235 46.4 0.00074
NP_001287755 (OMIM: 610872) E3 ubiquitin-protein l ( 731) 234 46.2 0.00082
XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409) 227 45.0 0.0011
XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409) 227 45.0 0.0011
XP_016861025 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 227 45.0 0.0011
XP_016861026 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 227 45.0 0.0011
XP_016861028 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 227 45.0 0.0011
XP_011531577 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 227 45.0 0.0011
XP_016861027 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 227 45.0 0.0011
XP_016861020 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493) 227 45.1 0.0012
XP_016861021 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493) 227 45.1 0.0012
NP_001304262 (OMIM: 605615) E3 ubiquitin-protein l ( 493) 227 45.1 0.0012
NP_006312 (OMIM: 605615) E3 ubiquitin-protein liga ( 493) 227 45.1 0.0012
NP_001304263 (OMIM: 605615) E3 ubiquitin-protein l ( 351) 218 43.7 0.0023
XP_016868793 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 784) 214 43.3 0.0064
XP_011515258 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 784) 214 43.3 0.0064
NP_001267468 (OMIM: 607119) E3 ubiquitin-protein l ( 838) 214 43.4 0.0067
XP_016868791 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 214 43.4 0.0067
NP_904355 (OMIM: 607119) E3 ubiquitin-protein liga ( 838) 214 43.4 0.0067
XP_016868792 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 214 43.4 0.0067
XP_005250910 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 214 43.4 0.0067
NP_056250 (OMIM: 607119) E3 ubiquitin-protein liga ( 838) 214 43.4 0.0067
>>NP_060469 (OMIM: 612487) E3 ubiquitin-protein ligase R (1072 aa)
initn: 7573 init1: 7573 opt: 7573 Z-score: 5905.0 bits: 1104.3 E(85289): 0
Smith-Waterman score: 7573; 100.0% identity (100.0% similar) in 1072 aa overlap (1-1072:1-1072)
10 20 30 40 50 60
pF1KB7 MPGEEEERAFLVAREELASALRRDSGQAFSLEQLRPLLASSLPLAARYLQLDAARLVRCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MPGEEEERAFLVAREELASALRRDSGQAFSLEQLRPLLASSLPLAARYLQLDAARLVRCN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AHGEPRNYLNTLSTALNILEKYGRNLLSPQRPRYWRGVKFNNPVFRSTVDAVQGGRDVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AHGEPRNYLNTLSTALNILEKYGRNLLSPQRPRYWRGVKFNNPVFRSTVDAVQGGRDVLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 LYGYTEEQPDGLSFPEGQEEPDEHQVATVTLEVLLLRTELSLLLQNTHPRQQALEQLLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LYGYTEEQPDGLSFPEGQEEPDEHQVATVTLEVLLLRTELSLLLQNTHPRQQALEQLLED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KVEDDMLQLSEFDPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGTLHCPSCKQALCPAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KVEDDMLQLSEFDPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGTLHCPSCKQALCPAC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DHLFHGHPSRAHHLRQTLPGVLQGTHLSPSLPASAQPRPQSTSLLALGDSSLSSPNPASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DHLFHGHPSRAHHLRQTLPGVLQGTHLSPSLPASAQPRPQSTSLLALGDSSLSSPNPASA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 HLPWHCAACAMLNEPWAVLCVACDRPRGCKGLGLGTEGPQGTGGLEPDLARGRWACQSCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HLPWHCAACAMLNEPWAVLCVACDRPRGCKGLGLGTEGPQGTGGLEPDLARGRWACQSCT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 FENEAAAVLCSICERPRLAQPPSLVVDSRDAGICLQPLQQGDALLASAQSQVWYCIHCTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FENEAAAVLCSICERPRLAQPPSLVVDSRDAGICLQPLQQGDALLASAQSQVWYCIHCTF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 CNSSPGWVCVMCNRTSSPIPAQHAPRPYASSLEKGPPKPGPPRRLSAPLPSSCGDPEKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CNSSPGWVCVMCNRTSSPIPAQHAPRPYASSLEKGPPKPGPPRRLSAPLPSSCGDPEKQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 QDKMREEGLQLVSMIREGEAAGACPEEIFSALQYSGTEVPLQWLRSELPYVLEMVAELAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QDKMREEGLQLVSMIREGEAAGACPEEIFSALQYSGTEVPLQWLRSELPYVLEMVAELAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 QQDPGLGAFSCQEARRAWLDRHGNLDEAVEECVRTRRRKVQELQSLGFGPEEGSLQALFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QQDPGLGAFSCQEARRAWLDRHGNLDEAVEECVRTRRRKVQELQSLGFGPEEGSLQALFQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 HGGDVSRALTELQRQRLEPFRQRLWDSGPEPTPSWDGPDKQSLVRRLLAVYALPSWGRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HGGDVSRALTELQRQRLEPFRQRLWDSGPEPTPSWDGPDKQSLVRRLLAVYALPSWGRAE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 LALSLLQETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LALSLLQETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 ICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 FHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 CEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 CYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB7 ARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB7 YEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK
1030 1040 1050 1060 1070
>>NP_001297261 (OMIM: 612487) E3 ubiquitin-protein ligas (921 aa)
initn: 6513 init1: 6513 opt: 6513 Z-score: 5080.1 bits: 951.5 E(85289): 0
Smith-Waterman score: 6513; 99.9% identity (99.9% similar) in 910 aa overlap (163-1072:12-921)
140 150 160 170 180 190
pF1KB7 SFPEGQEEPDEHQVATVTLEVLLLRTELSLLLQNTHPRQQALEQLLEDKVEDDMLQLSEF
: ::::::::::::::::::::::::::::
NP_001 MDLCTRAGEPSLTQNTHPRQQALEQLLEDKVEDDMLQLSEF
10 20 30 40
200 210 220 230 240 250
pF1KB7 DPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGTLHCPSCKQALCPACDHLFHGHPSRAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGTLHCPSCKQALCPACDHLFHGHPSRAH
50 60 70 80 90 100
260 270 280 290 300 310
pF1KB7 HLRQTLPGVLQGTHLSPSLPASAQPRPQSTSLLALGDSSLSSPNPASAHLPWHCAACAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLRQTLPGVLQGTHLSPSLPASAQPRPQSTSLLALGDSSLSSPNPASAHLPWHCAACAML
110 120 130 140 150 160
320 330 340 350 360 370
pF1KB7 NEPWAVLCVACDRPRGCKGLGLGTEGPQGTGGLEPDLARGRWACQSCTFENEAAAVLCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEPWAVLCVACDRPRGCKGLGLGTEGPQGTGGLEPDLARGRWACQSCTFENEAAAVLCSI
170 180 190 200 210 220
380 390 400 410 420 430
pF1KB7 CERPRLAQPPSLVVDSRDAGICLQPLQQGDALLASAQSQVWYCIHCTFCNSSPGWVCVMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CERPRLAQPPSLVVDSRDAGICLQPLQQGDALLASAQSQVWYCIHCTFCNSSPGWVCVMC
230 240 250 260 270 280
440 450 460 470 480 490
pF1KB7 NRTSSPIPAQHAPRPYASSLEKGPPKPGPPRRLSAPLPSSCGDPEKQRQDKMREEGLQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRTSSPIPAQHAPRPYASSLEKGPPKPGPPRRLSAPLPSSCGDPEKQRQDKMREEGLQLV
290 300 310 320 330 340
500 510 520 530 540 550
pF1KB7 SMIREGEAAGACPEEIFSALQYSGTEVPLQWLRSELPYVLEMVAELAGQQDPGLGAFSCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMIREGEAAGACPEEIFSALQYSGTEVPLQWLRSELPYVLEMVAELAGQQDPGLGAFSCQ
350 360 370 380 390 400
560 570 580 590 600 610
pF1KB7 EARRAWLDRHGNLDEAVEECVRTRRRKVQELQSLGFGPEEGSLQALFQHGGDVSRALTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARRAWLDRHGNLDEAVEECVRTRRRKVQELQSLGFGPEEGSLQALFQHGGDVSRALTEL
410 420 430 440 450 460
620 630 640 650 660 670
pF1KB7 QRQRLEPFRQRLWDSGPEPTPSWDGPDKQSLVRRLLAVYALPSWGRAELALSLLQETPRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRQRLEPFRQRLWDSGPEPTPSWDGPDKQSLVRRLLAVYALPSWGRAELALSLLQETPRN
470 480 490 500 510 520
680 690 700 710 720 730
pF1KB7 YELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTI
530 540 550 560 570 580
740 750 760 770 780 790
pF1KB7 ALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMR
590 600 610 620 630 640
800 810 820 830 840 850
pF1KB7 DPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMND
650 660 670 680 690 700
860 870 880 890 900 910
pF1KB7 PEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCP
710 720 730 740 750 760
920 930 940 950 960 970
pF1KB7 EPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVI
770 780 790 800 810 820
980 990 1000 1010 1020 1030
pF1KB7 EQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATER
830 840 850 860 870 880
1040 1050 1060 1070
pF1KB7 YLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK
::::::::::::::::::::::::::::::::::::::::
NP_001 YLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK
890 900 910 920
>>XP_006710421 (OMIM: 610872) PREDICTED: E3 ubiquitin-pr (588 aa)
initn: 175 init1: 108 opt: 235 Z-score: 191.5 bits: 46.3 E(85289): 0.00063
Smith-Waterman score: 305; 24.7% identity (50.3% similar) in 288 aa overlap (698-966:118-366)
670 680 690 700 710 720
pF1KB7 ETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFR
:: .: :: .: : :: : ::.:
XP_006 AEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLR
90 100 110 120 130 140
730 740 750 760 770 780
pF1KB7 QHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTE
... . ..:... . :: :.. .. ::.: . .: . ... . .
XP_006 HYLRLEISESRVP-ISCPECSE-----------RLNPHDIRLLLA-DPPLMHKYEEFMLR
150 160 170 180 190
790 800 810 820 830
pF1KB7 GVLMRDPKFLWCA--QCSFGFIYEREQLEATCPQ-------CHQTFCVRCKRQWEEQHRG
: :: :: .:... : :.::. :. :: .::. : : .
XP_006 RYLASDPDCRWCPAPDCGYAVI---AYGCASCPKLTCEREGCQTEFCYHCKQIW---HPN
200 210 220 230 240
840 850 860 870 880
pF1KB7 RSCEDFQNWKRMNDPEYQAQ---GLAMYLQENG-ID----CPKCK-FSYALARGGCMHFH
..: :. .: . . ... ::. : ::.: : ::.:. . . :.: :.
XP_006 QTC-DMARQQRAQTLRVRTKHTSGLS-YGQESGPADDIKPCPRCSAYIIKMNDGSCNHMT
250 260 270 280 290 300
890 900 910 920 930 940
pF1KB7 CTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFY-LRDWTALRLQKLLQD
:. : .:: :.. . ..:: : : :. . :. : .:.: .
XP_006 CAVCGCEFCWLCMKEI--------------SDLHYLSPSGCTFWGKKPWS--RKKKILWQ
310 320 330 340 350
950 960 970 980 990 1000
pF1KB7 NNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVS
...... :.: . :
XP_006 LGTLIGA--PVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTL
360 370 380 390 400
>>NP_001120833 (OMIM: 610872) E3 ubiquitin-protein ligas (587 aa)
initn: 175 init1: 108 opt: 234 Z-score: 190.7 bits: 46.1 E(85289): 0.00069
Smith-Waterman score: 315; 24.7% identity (50.5% similar) in 287 aa overlap (698-966:118-365)
670 680 690 700 710 720
pF1KB7 ETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFR
:: .: :: .: : :: : ::.:
NP_001 AEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLR
90 100 110 120 130 140
730 740 750 760 770 780
pF1KB7 QHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTE
... . ..:... . :: :.. .. ::.: . .: . ... . .
NP_001 HYLRLEISESRVP-ISCPECSE-----------RLNPHDIRLLLA-DPPLMHKYEEFMLR
150 160 170 180 190
790 800 810 820 830
pF1KB7 GVLMRDPKFLWCA--QCSFGFIYEREQLEATCPQ-------CHQTFCVRCKRQWEEQHRG
: :: :: .:... : :.::. :. :: .::. : : .
NP_001 RYLASDPDCRWCPAPDCGYAVI---AYGCASCPKLTCEREGCQTEFCYHCKQIW---HPN
200 210 220 230 240
840 850 860 870 880 890
pF1KB7 RSCEDFQNWKRMNDPEYQAQ---GLAMYLQENGID----CPKCK-FSYALARGGCMHFHC
..: :. .: . . ... ::. : ::.: : ::.:. . . :.: :. :
NP_001 QTC-DMARQQRAQTLRVRTKHTSGLS-YGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTC
250 260 270 280 290 300
900 910 920 930 940
pF1KB7 TQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFY-LRDWTALRLQKLLQDN
. : .:: :.. . ..:: : : :. . :. : .:.: .
NP_001 AVCGCEFCWLCMKEI--------------SDLHYLSPSGCTFWGKKPWS--RKKKILWQL
310 320 330 340 350
950 960 970 980 990 1000
pF1KB7 NVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSL
...... :.: . :
NP_001 GTLIGA--PVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLS
360 370 380 390 400
>>XP_006710420 (OMIM: 610872) PREDICTED: E3 ubiquitin-pr (688 aa)
initn: 208 init1: 108 opt: 235 Z-score: 190.6 bits: 46.3 E(85289): 0.00071
Smith-Waterman score: 305; 24.7% identity (50.3% similar) in 288 aa overlap (698-966:118-366)
670 680 690 700 710 720
pF1KB7 ETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFR
:: .: :: .: : :: : ::.:
XP_006 AEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLR
90 100 110 120 130 140
730 740 750 760 770 780
pF1KB7 QHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTE
... . ..:... . :: :.. .. ::.: . .: . ... . .
XP_006 HYLRLEISESRVP-ISCPECSE-----------RLNPHDIRLLLA-DPPLMHKYEEFMLR
150 160 170 180 190
790 800 810 820 830
pF1KB7 GVLMRDPKFLWCA--QCSFGFIYEREQLEATCPQ-------CHQTFCVRCKRQWEEQHRG
: :: :: .:... : :.::. :. :: .::. : : .
XP_006 RYLASDPDCRWCPAPDCGYAVI---AYGCASCPKLTCEREGCQTEFCYHCKQIW---HPN
200 210 220 230 240
840 850 860 870 880
pF1KB7 RSCEDFQNWKRMNDPEYQAQ---GLAMYLQENG-ID----CPKCK-FSYALARGGCMHFH
..: :. .: . . ... ::. : ::.: : ::.:. . . :.: :.
XP_006 QTC-DMARQQRAQTLRVRTKHTSGLS-YGQESGPADDIKPCPRCSAYIIKMNDGSCNHMT
250 260 270 280 290 300
890 900 910 920 930 940
pF1KB7 CTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFY-LRDWTALRLQKLLQD
:. : .:: :.. . ..:: : : :. . :. : .:.: .
XP_006 CAVCGCEFCWLCMKEI--------------SDLHYLSPSGCTFWGKKPWS--RKKKILWQ
310 320 330 340 350
950 960 970 980 990 1000
pF1KB7 NNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVS
...... :.: . :
XP_006 LGTLIGA--PVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTL
360 370 380 390 400
>>XP_006710419 (OMIM: 610872) PREDICTED: E3 ubiquitin-pr (732 aa)
initn: 208 init1: 108 opt: 235 Z-score: 190.2 bits: 46.4 E(85289): 0.00074
Smith-Waterman score: 305; 24.7% identity (50.3% similar) in 288 aa overlap (698-966:118-366)
670 680 690 700 710 720
pF1KB7 ETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFR
:: .: :: .: : :: : ::.:
XP_006 AEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLR
90 100 110 120 130 140
730 740 750 760 770 780
pF1KB7 QHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTE
... . ..:... . :: :.. .. ::.: . .: . ... . .
XP_006 HYLRLEISESRVP-ISCPECSE-----------RLNPHDIRLLLA-DPPLMHKYEEFMLR
150 160 170 180 190
790 800 810 820 830
pF1KB7 GVLMRDPKFLWCA--QCSFGFIYEREQLEATCPQ-------CHQTFCVRCKRQWEEQHRG
: :: :: .:... : :.::. :. :: .::. : : .
XP_006 RYLASDPDCRWCPAPDCGYAVI---AYGCASCPKLTCEREGCQTEFCYHCKQIW---HPN
200 210 220 230 240
840 850 860 870 880
pF1KB7 RSCEDFQNWKRMNDPEYQAQ---GLAMYLQENG-ID----CPKCK-FSYALARGGCMHFH
..: :. .: . . ... ::. : ::.: : ::.:. . . :.: :.
XP_006 QTC-DMARQQRAQTLRVRTKHTSGLS-YGQESGPADDIKPCPRCSAYIIKMNDGSCNHMT
250 260 270 280 290 300
890 900 910 920 930 940
pF1KB7 CTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFY-LRDWTALRLQKLLQD
:. : .:: :.. . ..:: : : :. . :. : .:.: .
XP_006 CAVCGCEFCWLCMKEI--------------SDLHYLSPSGCTFWGKKPWS--RKKKILWQ
310 320 330 340 350
950 960 970 980 990 1000
pF1KB7 NNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVS
...... :.: . :
XP_006 LGTLIGA--PVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTL
360 370 380 390 400
>>NP_699172 (OMIM: 610872) E3 ubiquitin-protein ligase R (732 aa)
initn: 208 init1: 108 opt: 235 Z-score: 190.2 bits: 46.4 E(85289): 0.00074
Smith-Waterman score: 305; 24.7% identity (50.3% similar) in 288 aa overlap (698-966:118-366)
670 680 690 700 710 720
pF1KB7 ETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFR
:: .: :: .: : :: : ::.:
NP_699 AEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLR
90 100 110 120 130 140
730 740 750 760 770 780
pF1KB7 QHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTE
... . ..:... . :: :.. .. ::.: . .: . ... . .
NP_699 HYLRLEISESRVP-ISCPECSE-----------RLNPHDIRLLLA-DPPLMHKYEEFMLR
150 160 170 180 190
790 800 810 820 830
pF1KB7 GVLMRDPKFLWCA--QCSFGFIYEREQLEATCPQ-------CHQTFCVRCKRQWEEQHRG
: :: :: .:... : :.::. :. :: .::. : : .
NP_699 RYLASDPDCRWCPAPDCGYAVI---AYGCASCPKLTCEREGCQTEFCYHCKQIW---HPN
200 210 220 230 240
840 850 860 870 880
pF1KB7 RSCEDFQNWKRMNDPEYQAQ---GLAMYLQENG-ID----CPKCK-FSYALARGGCMHFH
..: :. .: . . ... ::. : ::.: : ::.:. . . :.: :.
NP_699 QTC-DMARQQRAQTLRVRTKHTSGLS-YGQESGPADDIKPCPRCSAYIIKMNDGSCNHMT
250 260 270 280 290 300
890 900 910 920 930 940
pF1KB7 CTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFY-LRDWTALRLQKLLQD
:. : .:: :.. . ..:: : : :. . :. : .:.: .
NP_699 CAVCGCEFCWLCMKEI--------------SDLHYLSPSGCTFWGKKPWS--RKKKILWQ
310 320 330 340 350
950 960 970 980 990 1000
pF1KB7 NNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVS
...... :.: . :
NP_699 LGTLIGA--PVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTL
360 370 380 390 400
>>NP_001287755 (OMIM: 610872) E3 ubiquitin-protein ligas (731 aa)
initn: 171 init1: 108 opt: 234 Z-score: 189.4 bits: 46.2 E(85289): 0.00082
Smith-Waterman score: 315; 24.7% identity (50.5% similar) in 287 aa overlap (698-966:118-365)
670 680 690 700 710 720
pF1KB7 ETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFR
:: .: :: .: : :: : ::.:
NP_001 AEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCLR
90 100 110 120 130 140
730 740 750 760 770 780
pF1KB7 QHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTE
... . ..:... . :: :.. .. ::.: . .: . ... . .
NP_001 HYLRLEISESRVP-ISCPECSE-----------RLNPHDIRLLLA-DPPLMHKYEEFMLR
150 160 170 180 190
790 800 810 820 830
pF1KB7 GVLMRDPKFLWCA--QCSFGFIYEREQLEATCPQ-------CHQTFCVRCKRQWEEQHRG
: :: :: .:... : :.::. :. :: .::. : : .
NP_001 RYLASDPDCRWCPAPDCGYAVI---AYGCASCPKLTCEREGCQTEFCYHCKQIW---HPN
200 210 220 230 240
840 850 860 870 880 890
pF1KB7 RSCEDFQNWKRMNDPEYQAQ---GLAMYLQENGID----CPKCK-FSYALARGGCMHFHC
..: :. .: . . ... ::. : ::.: : ::.:. . . :.: :. :
NP_001 QTC-DMARQQRAQTLRVRTKHTSGLS-YGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTC
250 260 270 280 290 300
900 910 920 930 940
pF1KB7 TQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFY-LRDWTALRLQKLLQDN
. : .:: :.. . ..:: : : :. . :. : .:.: .
NP_001 AVCGCEFCWLCMKEI--------------SDLHYLSPSGCTFWGKKPWS--RKKKILWQL
310 320 330 340 350
950 960 970 980 990 1000
pF1KB7 NVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSL
...... :.: . :
NP_001 GTLIGA--PVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLS
360 370 380 390 400
>>XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr (409 aa)
initn: 198 init1: 102 opt: 227 Z-score: 187.4 bits: 45.0 E(85289): 0.0011
Smith-Waterman score: 281; 23.0% identity (53.1% similar) in 256 aa overlap (697-937:53-288)
670 680 690 700 710 720
pF1KB7 QETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCF
..:::: . .. . .: .:. .: .:.
XP_016 DRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSL-ACQHQFCRSCW
30 40 50 60 70 80
730 740 750 760 770 780
pF1KB7 RQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLT
.:: .. .:. . . : : : : . .. . . .:::. ... :
XP_016 EQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLP--NEELREK--------YRRYLF
90 100 110 120 130
790 800 810 820 830 840
pF1KB7 EGVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCED
. . .. : :.: . . . : . .. : .:...:: .:.... : .:
XP_016 RDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMY---HAPTDCAT
140 150 160 170 180
850 860 870 880 890 900
pF1KB7 FQNW--KRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGC
...: : .: : : :.. . :::::.. ::: :..:..:.:.:: :
XP_016 IRKWLTKCADDSE-----TANYISAHTKDCPKCNICIE-KNGGCNHMQCSKCKHDFCWMC
190 200 210 220 230 240
910 920 930 940 950
pF1KB7 Y-------NAFYAKNKCPEPNCRVKKSLHGHHP---RDCLFYLRDWTALRLQKLLQDNNV
. .: .. : :..: ... . :::.. :
XP_016 LGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTY
250 260 270 280 290 300
960 970 980 990 1000 1010
pF1KB7 MFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLIN
XP_016 QRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQ
310 320 330 340 350 360
>>XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr (409 aa)
initn: 198 init1: 102 opt: 227 Z-score: 187.4 bits: 45.0 E(85289): 0.0011
Smith-Waterman score: 281; 23.0% identity (53.1% similar) in 256 aa overlap (697-937:53-288)
670 680 690 700 710 720
pF1KB7 QETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCF
..:::: . .. . .: .:. .: .:.
XP_016 DRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSL-ACQHQFCRSCW
30 40 50 60 70 80
730 740 750 760 770 780
pF1KB7 RQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLT
.:: .. .:. . . : : : : . .. . . .:::. ... :
XP_016 EQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLP--NEELREK--------YRRYLF
90 100 110 120 130
790 800 810 820 830 840
pF1KB7 EGVLMRDPKFLWC--AQCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCED
. . .. : :.: . . . : . .. : .:...:: .:.... : .:
XP_016 RDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMY---HAPTDCAT
140 150 160 170 180
850 860 870 880 890 900
pF1KB7 FQNW--KRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGC
...: : .: : : :.. . :::::.. ::: :..:..:.:.:: :
XP_016 IRKWLTKCADDSE-----TANYISAHTKDCPKCNICIE-KNGGCNHMQCSKCKHDFCWMC
190 200 210 220 230 240
910 920 930 940 950
pF1KB7 Y-------NAFYAKNKCPEPNCRVKKSLHGHHP---RDCLFYLRDWTALRLQKLLQDNNV
. .: .. : :..: ... . :::.. :
XP_016 LGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTY
250 260 270 280 290 300
960 970 980 990 1000 1010
pF1KB7 MFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLIN
XP_016 QRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQ
310 320 330 340 350 360
1072 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:11:18 2016 done: Thu Nov 3 18:11:21 2016
Total Scan time: 17.730 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]