FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7024, 426 aa 1>>>pF1KB7024 426 - 426 aa - 426 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3349+/-0.0003; mu= 15.3183+/- 0.019 mean_var=160.2391+/-32.039, 0's: 0 Z-trim(122.5): 48 B-trim: 0 in 0/51 Lambda= 0.101319 statistics sampled from 40773 (40830) to 40773 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.479), width: 16 Scan time: 9.120 The best scores are: opt bits E(85289) NP_005895 (OMIM: 602932,612229) mothers against de ( 426) 3033 454.9 1.8e-127 NP_001177750 (OMIM: 602932,612229) mothers against ( 425) 3016 452.4 1e-126 NP_001177751 (OMIM: 602932,612229) mothers against ( 211) 1494 229.5 6.1e-60 NP_001177752 (OMIM: 602932,612229) mothers against ( 238) 1457 224.2 2.8e-58 NP_005576 (OMIM: 602931,614823) mothers against de ( 496) 1112 174.1 6.8e-43 XP_011519863 (OMIM: 602931,614823) PREDICTED: moth ( 235) 842 134.3 3.2e-31 XP_011519861 (OMIM: 603109,613795) PREDICTED: moth ( 381) 473 80.6 7.5e-15 XP_005266460 (OMIM: 603295,615342) PREDICTED: moth ( 393) 353 63.1 1.5e-09 XP_016881239 (OMIM: 601366) PREDICTED: mothers aga ( 227) 324 58.6 1.9e-08 NP_001138574 (OMIM: 603109,613795) mothers against ( 320) 324 58.7 2.4e-08 NP_001138576 (OMIM: 603109,613795) mothers against ( 230) 313 57.0 6e-08 >>NP_005895 (OMIM: 602932,612229) mothers against decape (426 aa) initn: 3033 init1: 3033 opt: 3033 Z-score: 2409.4 bits: 454.9 E(85289): 1.8e-127 Smith-Waterman score: 3033; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426) 10 20 30 40 50 60 pF1KB7 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE 370 380 390 400 410 420 pF1KB7 VIFNSR :::::: NP_005 VIFNSR >>NP_001177750 (OMIM: 602932,612229) mothers against dec (425 aa) initn: 1588 init1: 1588 opt: 3016 Z-score: 2395.9 bits: 452.4 E(85289): 1e-126 Smith-Waterman score: 3016; 99.8% identity (99.8% similar) in 426 aa overlap (1-426:1-425) 10 20 30 40 50 60 pF1KB7 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: NP_001 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPT-DCPDAVPSSAETGGTNY 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB7 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB7 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE 360 370 380 390 400 410 pF1KB7 VIFNSR :::::: NP_001 VIFNSR 420 >>NP_001177751 (OMIM: 602932,612229) mothers against dec (211 aa) initn: 1494 init1: 1494 opt: 1494 Z-score: 1197.1 bits: 229.5 E(85289): 6.1e-60 Smith-Waterman score: 1494; 100.0% identity (100.0% similar) in 211 aa overlap (216-426:1-211) 190 200 210 220 230 240 pF1KB7 INPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNYLAPGG :::::::::::::::::::::::::::::: NP_001 MDFLKPTADCPDAVPSSAETGGTNYLAPGG 10 20 30 250 260 270 280 290 300 pF1KB7 LSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDN 40 50 60 70 80 90 310 320 330 340 350 360 pF1KB7 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFS 100 110 120 130 140 150 370 380 390 400 410 420 pF1KB7 IKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNS 160 170 180 190 200 210 pF1KB7 R : NP_001 R >>NP_001177752 (OMIM: 602932,612229) mothers against dec (238 aa) initn: 1457 init1: 1457 opt: 1457 Z-score: 1167.3 bits: 224.2 E(85289): 2.8e-58 Smith-Waterman score: 1457; 98.6% identity (99.5% similar) in 209 aa overlap (218-426:30-238) 190 200 210 220 230 240 pF1KB7 PELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNYLAPGGLS ..: :::::::::::::::::::::::::: NP_001 MCGLSFMLFRACLKMDLGVFICVFISFSPLFKSTADCPDAVPSSAETGGTNYLAPGGLS 10 20 30 40 50 250 260 270 280 290 300 pF1KB7 DSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKS 60 70 80 90 100 110 310 320 330 340 350 360 pF1KB7 QLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIK 120 130 140 150 160 170 370 380 390 400 410 420 pF1KB7 AFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNSR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNSR 180 190 200 210 220 230 >>NP_005576 (OMIM: 602931,614823) mothers against decape (496 aa) initn: 1307 init1: 559 opt: 1112 Z-score: 891.0 bits: 174.1 E(85289): 6.8e-43 Smith-Waterman score: 1251; 47.7% identity (68.5% similar) in 444 aa overlap (17-425:66-494) 10 20 30 pF1KB7 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGG----GGGELR---- : : ..:: :.: .:: : NP_005 DGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSE 40 50 60 70 80 90 40 50 60 70 80 pF1KB7 -GEGATDSRAHGAGGGGPG--------RAGCCLGKAVRGAKGHHHPHPPAAGAG--AAGG : :: .: : :::: . ::: . .: . . : :::. ::: NP_005 PGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGG 100 110 120 130 140 150 90 100 110 120 130 pF1KB7 A------------EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGRLDCR . : .::..:.:.::.::::.:. ::.:::::::. .:.:.: : : : NP_005 GRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVP-RADLR 160 170 180 190 200 210 140 150 160 170 180 190 pF1KB7 LGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKI-NPELVCCN :: .::: ::. ::: ..::::::.:. :.: :: :.:.. . :::: NP_005 LG------GQPA-PPQ-----LLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCN 220 230 240 250 260 200 210 220 230 240 250 pF1KB7 PHHLSRLCELESPPPPYSRY-PMDFLKPTADCPDAVPSSAETGGTNYL--APGGLSDSQL :.:.:::: ::::::::: : : :: : :.. : .:: .:: : ::: .::... NP_005 PYHFSRLCGPESPPPPYSRLSPRDEYKPL-DLSDSTLSYTETEATNSLITAPGEFSDASM 270 280 290 300 310 320 260 270 280 290 300 310 pF1KB7 LLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQ . :::: :::::..::::::: : . ...::::::::.:::::::: ...:. :. NP_005 SPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVR 330 340 350 360 370 380 320 330 340 350 360 370 pF1KB7 KVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDY ..::::: :: :..: ::::.:::. .:::..: ::: : .:.:.:.:: ::.:::.::. NP_005 RTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDF 390 400 410 420 430 440 380 390 400 410 420 pF1KB7 EKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNSR :.. .::. . . . :. .:.:::.:::: ::.::::.:::::::...:. NP_005 ERS-GLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR 450 460 470 480 490 >>XP_011519863 (OMIM: 602931,614823) PREDICTED: mothers (235 aa) initn: 850 init1: 559 opt: 842 Z-score: 681.5 bits: 134.3 E(85289): 3.2e-31 Smith-Waterman score: 842; 54.5% identity (79.0% similar) in 224 aa overlap (205-425:12-233) 180 190 200 210 220 230 pF1KB7 KRLCCCESYGKINPELVCCNPHHLSRLCELESPPPPYSRY-PMDFLKPTADCPDAVPSSA .:::::::: : : :: : :.. : . XP_011 MSRMGKPIETQKSPPPPYSRLSPRDEYKPL-DLSDSTLSYT 10 20 30 40 240 250 260 270 280 290 pF1KB7 ETGGTNYL--APGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLP :: .:: : ::: .::... . :::: :::::..::::::: : . ...:::::: XP_011 ETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLP 50 60 70 80 90 100 300 310 320 330 340 350 pF1KB7 QGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPD ::.:::::::: ...:. :...::::: :: :..: ::::.:::. .:::..: ::: : XP_011 QGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPG 110 120 130 140 150 160 360 370 380 390 400 410 pF1KB7 SRTLLVHKVFPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQF .:.:.:.:: ::.:::.::.:.. .::. . . . :. .:.:::.:::: ::.::: XP_011 GRALVVRKVPPGYSIKVFDFERS-GLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQF 170 180 190 200 210 420 pF1KB7 ISSCPCWLEVIFNSR :.:::::::...:. XP_011 ITSCPCWLEILLNNPR 220 230 >>XP_011519861 (OMIM: 603109,613795) PREDICTED: mothers (381 aa) initn: 339 init1: 172 opt: 473 Z-score: 387.6 bits: 80.6 E(85289): 7.5e-15 Smith-Waterman score: 520; 30.4% identity (58.0% similar) in 352 aa overlap (86-424:25-357) 60 70 80 90 100 110 pF1KB7 GRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKER-QLELLLQA : : . ..:..::::. ::. : .: XP_011 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKA 10 20 30 40 50 120 130 140 150 160 170 pF1KB7 VESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP-LLLCKVFRWPDLRHSSE . ... . : :. .: :: :: : .:: .. :...:::::. : XP_011 ITTQN-VNTKCITIPRSLDGRL-----------QVSHRKGLPHVIYCRLWRWPDLHSHHE 60 70 80 90 100 180 190 200 210 220 230 pF1KB7 VKRLCCCESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSA .. . :: ... . :: ::.: .:. :.::: : :. .. : . . XP_011 LRAMELCEFAFNMKKDEVCVNPYHYQRVETPETPPPGY-------LSEDGETSDHQMNHS 110 120 130 140 150 240 250 260 270 280 pF1KB7 ETGGTNYLAPGGLSDSQ--LLLEP---GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DI .:. :.:. .: .. : :.: . . :: ..:.: . :::. . ...::. : XP_011 MDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDG 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB7 FYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSAT : : ... :::: :.. :.. :. .: .:: :..: :.. :. ::..: . XP_011 FTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPN 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB7 LDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKG .. . . : :. :: ..: :. .. .: : :. : . : :...::::: XP_011 CNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKG 280 290 300 310 320 330 410 420 pF1KB7 WGQCYTRQFISSCPCWLEVIFNSR :: : :: ..: :::.:. .: XP_011 WGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 340 350 360 370 380 >>XP_005266460 (OMIM: 603295,615342) PREDICTED: mothers (393 aa) initn: 303 init1: 152 opt: 353 Z-score: 292.6 bits: 63.1 E(85289): 1.5e-09 Smith-Waterman score: 380; 29.7% identity (54.5% similar) in 330 aa overlap (98-413:40-347) 70 80 90 100 110 120 pF1KB7 GAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLEL-LLQAVESRGGTRTACL :..::::... . :. . : : . :. XP_005 LFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCV 10 20 30 40 50 60 130 140 150 160 170 180 pF1KB7 LLPGRLDCRLGPGAPAGAQPAQPPSSYSLP-LLLCKVFRWPDLRHSSEVKRLCCCE-SYG .: :: :: : .:: .. :.:.:::::. :.: : ::: .: XP_005 TIPRSLDGRL-----------QVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFG 70 80 90 100 110 190 200 210 220 230 240 pF1KB7 KINPELVCCNPHHLSRL-CELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNYLA- . . : :: ::.: :. ...:: :: ... .. : .: . :. XP_005 SKQKE-VCINPYHYRRVETPVDTPPLPYHA------TEASETQSGQPVDATADRHVVLSI 120 130 140 150 160 170 250 260 270 280 290 pF1KB7 PGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPS--LDIFYDLPQGNG--FCL :.: :: .::: :::.: ..:::. . .. : .: : : :..: ::: XP_005 PNGDFRPVCYEEP---QHWCSVAYYELNNRVGETFQASSRSVLIDGFTD-PSNNRNRFCL 180 190 200 210 220 300 310 320 330 340 350 pF1KB7 GQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLV : :.. :... ....: .:: :..: :.. :. ::..: . . . . : XP_005 GLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATV 230 240 250 260 270 280 360 370 380 390 400 410 pF1KB7 HKVFPGFSIKAFDYEKAYSLQRPNDH---EFMQQPWTGFTVQISFVK-GWGQCYTRQFIS :. : :.:.:. . .: . : : . . :...:::: . :.:.: XP_005 CKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKVAMKAGEPRKFLS 290 300 310 320 330 340 420 pF1KB7 SCPCWLEVIFNSR XP_005 GKERQLGLYMEVKAFSFITCYFVCCKVLANESSISKYGLIKVSGYV 350 360 370 380 390 >>XP_016881239 (OMIM: 601366) PREDICTED: mothers against (227 aa) initn: 277 init1: 131 opt: 324 Z-score: 272.4 bits: 58.6 E(85289): 1.9e-08 Smith-Waterman score: 342; 34.2% identity (60.9% similar) in 202 aa overlap (234-424:2-203) 210 220 230 240 250 260 pF1KB7 LESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNYLAPGGLS--DSQLLLEPGDRSH- .::. :.: :: . .: :.: :. XP_016 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 10 20 30 270 280 290 300 310 pF1KB7 --WCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSK :: .::.: . :::. . ...::: : : : ... :::: :.. :.. :. .: . XP_016 AFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRH 40 50 60 70 80 90 320 330 340 350 360 370 pF1KB7 IGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAY :: :..: :.. :. ::..: . .. . . : :. :: ..: :. .. XP_016 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 100 110 120 130 140 150 380 390 400 410 420 pF1KB7 SL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNSR .: : :. : . : :...::::::: : :: ..: :::.:. .: XP_016 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 160 170 180 190 200 210 XP_016 VLTQMGSPSVRCSSMS 220 >>NP_001138574 (OMIM: 603109,613795) mothers against dec (320 aa) initn: 265 init1: 131 opt: 324 Z-score: 270.7 bits: 58.7 E(85289): 2.4e-08 Smith-Waterman score: 355; 28.0% identity (54.3% similar) in 293 aa overlap (180-424:4-296) 150 160 170 180 190 200 pF1KB7 PSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP- :: ... . :: ::.: .:. :: NP_001 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPV 10 20 30 210 220 230 pF1KB7 --PPYSRYPMDF-------------------LKPTADCPDAVPSS--AETG--------- : ... : .: ..: .. :.. : . .: : NP_001 LVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNH 40 50 60 70 80 90 240 250 260 270 280 pF1KB7 ----GTNYLAPGGLSDSQ--LLLEP---GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--D :. :.:. .: .. : :.: . . :: ..:.: . :::. . ...::. : NP_001 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB7 IFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSA : : ... :::: :.. :.. :. .: .:: :..: :.. :. ::..: NP_001 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB7 TLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVK . .. . . : :. :: ..: :. .. .: : :. : . : :...:::: NP_001 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 220 230 240 250 260 270 410 420 pF1KB7 GWGQCYTRQFISSCPCWLEVIFNSR ::: : :: ..: :::.:. .: NP_001 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 280 290 300 310 320 426 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:16:30 2016 done: Thu Nov 3 18:16:31 2016 Total Scan time: 9.120 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]