FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7034, 425 aa 1>>>pF1KB7034 425 - 425 aa - 425 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3862+/-0.000461; mu= 16.7304+/- 0.029 mean_var=121.3108+/-29.753, 0's: 0 Z-trim(110.0): 659 B-trim: 0 in 0/48 Lambda= 0.116446 statistics sampled from 17542 (18311) to 17542 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.57), E-opt: 0.2 (0.215), width: 16 Scan time: 8.410 The best scores are: opt bits E(85289) NP_001983 (OMIM: 187930) proteinase-activated rece ( 425) 2784 479.9 5.2e-135 NP_001298242 (OMIM: 187930) proteinase-activated r ( 304) 1987 345.9 8.5e-95 XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 791 145.1 3e-34 NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 791 145.1 3.1e-34 XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 712 132.0 3.7e-30 XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 712 132.0 3.7e-30 XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 706 130.7 5.7e-30 XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 706 130.7 5.7e-30 XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 706 130.7 5.7e-30 XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 706 130.7 5.7e-30 NP_835230 (OMIM: 300525) P2Y purinoceptor 8 [Homo ( 359) 706 130.7 5.7e-30 XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 706 130.7 5.7e-30 XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 706 130.7 5.7e-30 NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 676 125.7 1.9e-28 NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 672 125.0 3e-28 NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 613 115.2 3e-25 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 611 114.8 3.5e-25 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 611 114.8 3.5e-25 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 611 114.8 3.5e-25 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 584 110.2 8.1e-24 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 584 110.2 8.1e-24 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 584 110.3 8.6e-24 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 584 110.3 8.6e-24 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 584 110.3 8.6e-24 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 560 106.2 1.4e-22 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 560 106.2 1.4e-22 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 560 106.2 1.4e-22 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 560 106.2 1.4e-22 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 560 106.2 1.4e-22 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 560 106.2 1.4e-22 NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 541 103.0 1.3e-21 XP_005260196 (OMIM: 602779) PREDICTED: proteinase- ( 273) 534 101.7 2.4e-21 NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 530 101.2 4.7e-21 NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 530 101.2 4.7e-21 NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 530 101.2 4.7e-21 XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 529 101.0 5.1e-21 NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 529 101.0 5.1e-21 XP_005254102 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 527 100.6 6.2e-21 XP_005254103 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 527 100.6 6.2e-21 NP_543008 (OMIM: 606922) 2-oxoglutarate receptor 1 ( 337) 527 100.6 6.2e-21 NP_001333126 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 527 100.6 6.2e-21 NP_001333125 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 527 100.6 6.2e-21 XP_011519379 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 527 100.6 6.2e-21 NP_001333124 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 527 100.6 6.2e-21 NP_001333123 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 527 100.6 6.2e-21 XP_005254100 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 527 100.6 6.2e-21 XP_005254101 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 527 100.6 6.2e-21 XP_016873328 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 526 100.5 7.5e-21 XP_011543376 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 526 100.5 7.5e-21 XP_005274076 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 526 100.5 7.5e-21 >>NP_001983 (OMIM: 187930) proteinase-activated receptor (425 aa) initn: 2784 init1: 2784 opt: 2784 Z-score: 2544.9 bits: 479.9 E(85289): 5.2e-135 Smith-Waterman score: 2784; 99.8% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB7 MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 IMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 EQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSHTSTTEAAYFAYLLCVCVS ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 AVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIY 370 380 390 400 410 420 pF1KB7 KKLLT ::::: NP_001 KKLLT >>NP_001298242 (OMIM: 187930) proteinase-activated recep (304 aa) initn: 1987 init1: 1987 opt: 1987 Z-score: 1822.9 bits: 345.9 E(85289): 8.5e-95 Smith-Waterman score: 1987; 99.7% identity (100.0% similar) in 304 aa overlap (122-425:1-304) 100 110 120 130 140 150 pF1KB7 ASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLF :::::::::::::::::::::::::::::: NP_001 MAIVVFILKMKVKKPAVVYMLHLATADVLF 10 20 30 160 170 180 190 200 210 pF1KB7 VSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSL 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB7 SWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEGYYAYYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEGYYAYYF 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB7 SAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNV 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB7 LLIVHYSFLSHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKES :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKES 220 230 240 250 260 270 400 410 420 pF1KB7 SDPSSYNSSGQLMASKMDTCSSNLNNSIYKKLLT :::::::::::::::::::::::::::::::::: NP_001 SDPSSYNSSGQLMASKMDTCSSNLNNSIYKKLLT 280 290 300 >>XP_016864712 (OMIM: 600933) PREDICTED: proteinase-acti (383 aa) initn: 724 init1: 480 opt: 791 Z-score: 735.9 bits: 145.1 E(85289): 3e-34 Smith-Waterman score: 791; 40.4% identity (70.4% similar) in 334 aa overlap (88-418:47-375) 60 70 80 90 100 110 pF1KB7 DEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSL ..: ... ::.. :.:.: ::: ::::.: XP_016 RSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGL 20 30 40 50 60 70 120 130 140 150 160 170 pF1KB7 PLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRF : : ::. ::... : :.:::.:: .:: ::.: : .:.::.:.. :..: .: :: XP_016 PSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNV 80 90 100 110 120 130 180 190 200 210 220 230 pF1KB7 VTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPL . . :: ::: :::.:: .:..:. ..: :: : . . : :::: : . ..:: XP_016 LIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGISLAIWLLILLVTIPL 140 150 160 170 180 190 240 250 260 270 280 290 pF1KB7 LLKEQTIQVPGLNITTCHDVLNETLLEG-YYAYYFSAFSAVFFFVPLIISTVCYVSIIRC . .::: .:.:::::::::: : :: : .. :..: .::.: : .... :: .:: XP_016 YVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLF-PAFLTASAYVLMIRM 200 210 220 230 240 250 300 310 320 330 340 350 pF1KB7 LSSSAVANRS--KKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSHTSTTEAAYFAYL : :::. . : :..::. : ..:. ...::: :.:.::.::: :: ... .: :. XP_016 LRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHY-FLIKSQGQSHVYALYI 260 270 280 290 300 310 360 370 380 390 400 410 pF1KB7 LCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSN . .:.:... ::::..::..: . . .. . : :. .... : : ..: . ::. XP_016 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVS--LTSKKHSRKSSS 320 330 340 350 360 370 420 pF1KB7 LNNSIYKKLLT ..: XP_016 YSSSSTTVKTSY 380 >>NP_005233 (OMIM: 600933) proteinase-activated receptor (397 aa) initn: 724 init1: 480 opt: 791 Z-score: 735.7 bits: 145.1 E(85289): 3.1e-34 Smith-Waterman score: 791; 40.4% identity (70.4% similar) in 334 aa overlap (88-418:61-389) 60 70 80 90 100 110 pF1KB7 DEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSL ..: ... ::.. :.:.: ::: ::::.: NP_005 RSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGL 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB7 PLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRF : : ::. ::... : :.:::.:: .:: ::.: : .:.::.:.. :..: .: :: NP_005 PSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNV 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 VTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPL . . :: ::: :::.:: .:..:. ..: :: : . . : :::: : . ..:: NP_005 LIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGISLAIWLLILLVTIPL 160 170 180 190 200 240 250 260 270 280 290 pF1KB7 LLKEQTIQVPGLNITTCHDVLNETLLEG-YYAYYFSAFSAVFFFVPLIISTVCYVSIIRC . .::: .:.:::::::::: : :: : .. :..: .::.: : .... :: .:: NP_005 YVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLF-PAFLTASAYVLMIRM 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB7 LSSSAVANRS--KKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSHTSTTEAAYFAYL : :::. . : :..::. : ..:. ...::: :.:.::.::: :: ... .: :. NP_005 LRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHY-FLIKSQGQSHVYALYI 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB7 LCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSN . .:.:... ::::..::..: . . .. . : :. .... : : ..: . ::. NP_005 VALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVS--LTSKKHSRKSSS 330 340 350 360 370 380 420 pF1KB7 LNNSIYKKLLT ..: NP_005 YSSSSTTVKTSY 390 >>XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinocepto (548 aa) initn: 591 init1: 445 opt: 712 Z-score: 662.4 bits: 132.0 E(85289): 3.7e-30 Smith-Waterman score: 712; 35.3% identity (68.1% similar) in 317 aa overlap (79-389:187-500) 50 60 70 80 90 100 pF1KB7 NDKYEPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASG--YLTSSWLTLFVP : . :.: . : . .: . ... .: XP_006 CPLSPGGAQTASLCLLCQGSWHQLESPGEDPSRMQVPNSTGPDNATLQMLRNPAIAVALP 160 170 180 190 200 210 110 120 130 140 150 160 pF1KB7 SVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGS ::. : .::.: :.... :. .: ..:.:..:..:...:....:::::.: :. . XP_006 VVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRH 220 230 240 250 260 270 170 180 190 200 210 220 pF1KB7 DWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAI : :: :: ::.::: :::.::: :: ::..:::.:.::..: :: : .: . XP_006 HWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGT 280 290 300 310 320 330 230 240 250 260 270 280 pF1KB7 WALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEG---YYAYYFSAFSAVFFFVPL : : .... :: . : : .:.: :: :::. :.: . . .. :. : ..:..:. XP_006 WLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIF-ILLFLIPF 340 350 360 370 380 390 290 300 310 320 330 340 pF1KB7 IISTVCYV-SIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSH .:...::. .:.. : . . .: .. ::. :.:.:. :. ::.:.: .:..: ..:. XP_006 VITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAH--IVSR 400 410 420 430 440 450 350 360 370 380 390 400 pF1KB7 TSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQ .. : .: : .:.: .. :.::..::.:: : : . : :. XP_006 LFYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRES 460 470 480 490 500 510 410 420 pF1KB7 LMASKMDTCSSNLNNSIYKKLLT XP_006 LFSARTTSVRSEAGAHPEGMEGATRPGLQRQESVF 520 530 540 >>XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinocepto (548 aa) initn: 591 init1: 445 opt: 712 Z-score: 662.4 bits: 132.0 E(85289): 3.7e-30 Smith-Waterman score: 712; 35.3% identity (68.1% similar) in 317 aa overlap (79-389:187-500) 50 60 70 80 90 100 pF1KB7 NDKYEPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASG--YLTSSWLTLFVP : . :.: . : . .: . ... .: XP_006 CPLSPGGAQTASLCLLCQGSWHQLESPGEDPSRMQVPNSTGPDNATLQMLRNPAIAVALP 160 170 180 190 200 210 110 120 130 140 150 160 pF1KB7 SVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGS ::. : .::.: :.... :. .: ..:.:..:..:...:....:::::.: :. . XP_006 VVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRH 220 230 240 250 260 270 170 180 190 200 210 220 pF1KB7 DWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAI : :: :: ::.::: :::.::: :: ::..:::.:.::..: :: : .: . XP_006 HWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGT 280 290 300 310 320 330 230 240 250 260 270 280 pF1KB7 WALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEG---YYAYYFSAFSAVFFFVPL : : .... :: . : : .:.: :: :::. :.: . . .. :. : ..:..:. XP_006 WLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIF-ILLFLIPF 340 350 360 370 380 390 290 300 310 320 330 340 pF1KB7 IISTVCYV-SIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSH .:...::. .:.. : . . .: .. ::. :.:.:. :. ::.:.: .:..: ..:. XP_006 VITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAH--IVSR 400 410 420 430 440 450 350 360 370 380 390 400 pF1KB7 TSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQ .. : .: : .:.: .. :.::..::.:: : : . : :. XP_006 LFYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRES 460 470 480 490 500 510 410 420 pF1KB7 LMASKMDTCSSNLNNSIYKKLLT XP_006 LFSARTTSVRSEAGAHPEGMEGATRPGLQRQESVF 520 530 540 >>XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa) initn: 591 init1: 445 opt: 706 Z-score: 659.0 bits: 130.7 E(85289): 5.7e-30 Smith-Waterman score: 706; 35.5% identity (68.4% similar) in 313 aa overlap (83-389:2-311) 60 70 80 90 100 110 pF1KB7 EPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASG--YLTSSWLTLFVPSVYT :.: . : . .: . ... .: ::. XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYS 10 20 30 120 130 140 150 160 170 pF1KB7 GVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQF : .::.: :.... :. .: ..:.:..:..:...:....:::::.: :. . : : XP_011 LVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVF 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB7 GSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALA : :: ::.::: :::.::: :: ::..:::.:.::..: :: : .: . : : XP_011 GVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLL 100 110 120 130 140 150 240 250 260 270 280 pF1KB7 IAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEG---YYAYYFSAFSAVFFFVPLIIST .... :: . : : .:.: :: :::. :.: . . .. :. : ..:..:..:.. XP_011 LTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIF-ILLFLIPFVITV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB7 VCYV-SIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSHTSTT .::. .:.. : . . .: .. ::. :.:.:. :. ::.:.: .:..: ..:. XP_011 ACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAH--IVSRLFYG 220 230 240 250 260 350 360 370 380 390 400 pF1KB7 EAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMAS .. : .: : .:.: .. :.::..::.:: : : . : :. XP_011 KSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSA 270 280 290 300 310 320 410 420 pF1KB7 KMDTCSSNLNNSIYKKLLT XP_011 RTTSVRSEAGAHPEGMEGATRPGLQRQESVF 330 340 350 >>XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa) initn: 591 init1: 445 opt: 706 Z-score: 659.0 bits: 130.7 E(85289): 5.7e-30 Smith-Waterman score: 706; 35.5% identity (68.4% similar) in 313 aa overlap (83-389:2-311) 60 70 80 90 100 110 pF1KB7 EPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASG--YLTSSWLTLFVPSVYT :.: . : . .: . ... .: ::. XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYS 10 20 30 120 130 140 150 160 170 pF1KB7 GVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQF : .::.: :.... :. .: ..:.:..:..:...:....:::::.: :. . : : XP_011 LVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVF 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB7 GSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALA : :: ::.::: :::.::: :: ::..:::.:.::..: :: : .: . : : XP_011 GVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLL 100 110 120 130 140 150 240 250 260 270 280 pF1KB7 IAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEG---YYAYYFSAFSAVFFFVPLIIST .... :: . : : .:.: :: :::. :.: . . .. :. : ..:..:..:.. XP_011 LTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIF-ILLFLIPFVITV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB7 VCYV-SIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSHTSTT .::. .:.. : . . .: .. ::. :.:.:. :. ::.:.: .:..: ..:. XP_011 ACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAH--IVSRLFYG 220 230 240 250 260 350 360 370 380 390 400 pF1KB7 EAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMAS .. : .: : .:.: .. :.::..::.:: : : . : :. XP_011 KSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSA 270 280 290 300 310 320 410 420 pF1KB7 KMDTCSSNLNNSIYKKLLT XP_011 RTTSVRSEAGAHPEGMEGATRPGLQRQESVF 330 340 350 >>XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa) initn: 591 init1: 445 opt: 706 Z-score: 659.0 bits: 130.7 E(85289): 5.7e-30 Smith-Waterman score: 706; 35.5% identity (68.4% similar) in 313 aa overlap (83-389:2-311) 60 70 80 90 100 110 pF1KB7 EPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASG--YLTSSWLTLFVPSVYT :.: . : . .: . ... .: ::. XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYS 10 20 30 120 130 140 150 160 170 pF1KB7 GVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQF : .::.: :.... :. .: ..:.:..:..:...:....:::::.: :. . : : XP_011 LVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVF 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB7 GSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALA : :: ::.::: :::.::: :: ::..:::.:.::..: :: : .: . : : XP_011 GVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLL 100 110 120 130 140 150 240 250 260 270 280 pF1KB7 IAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEG---YYAYYFSAFSAVFFFVPLIIST .... :: . : : .:.: :: :::. :.: . . .. :. : ..:..:..:.. XP_011 LTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIF-ILLFLIPFVITV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB7 VCYV-SIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSHTSTT .::. .:.. : . . .: .. ::. :.:.:. :. ::.:.: .:..: ..:. XP_011 ACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAH--IVSRLFYG 220 230 240 250 260 350 360 370 380 390 400 pF1KB7 EAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMAS .. : .: : .:.: .. :.::..::.:: : : . : :. XP_011 KSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSA 270 280 290 300 310 320 410 420 pF1KB7 KMDTCSSNLNNSIYKKLLT XP_011 RTTSVRSEAGAHPEGMEGATRPGLQRQESVF 330 340 350 >>XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa) initn: 591 init1: 445 opt: 706 Z-score: 659.0 bits: 130.7 E(85289): 5.7e-30 Smith-Waterman score: 706; 35.5% identity (68.4% similar) in 313 aa overlap (83-389:2-311) 60 70 80 90 100 110 pF1KB7 EPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASG--YLTSSWLTLFVPSVYT :.: . : . .: . ... .: ::. XP_005 MQVPNSTGPDNATLQMLRNPAIAVALPVVYS 10 20 30 120 130 140 150 160 170 pF1KB7 GVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQF : .::.: :.... :. .: ..:.:..:..:...:....:::::.: :. . : : XP_005 LVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVF 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB7 GSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALA : :: ::.::: :::.::: :: ::..:::.:.::..: :: : .: . : : XP_005 GVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLL 100 110 120 130 140 150 240 250 260 270 280 pF1KB7 IAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEG---YYAYYFSAFSAVFFFVPLIIST .... :: . : : .:.: :: :::. :.: . . .. :. : ..:..:..:.. XP_005 LTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIF-ILLFLIPFVITV 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB7 VCYV-SIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIVHYSFLSHTSTT .::. .:.. : . . .: .. ::. :.:.:. :. ::.:.: .:..: ..:. XP_005 ACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAH--IVSRLFYG 220 230 240 250 260 350 360 370 380 390 400 pF1KB7 EAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMAS .. : .: : .:.: .. :.::..::.:: : : . : :. XP_005 KSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSA 270 280 290 300 310 320 410 420 pF1KB7 KMDTCSSNLNNSIYKKLLT XP_005 RTTSVRSEAGAHPEGMEGATRPGLQRQESVF 330 340 350 425 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 11 16:59:04 2016 done: Fri Nov 11 16:59:05 2016 Total Scan time: 8.410 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]