FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7045, 476 aa 1>>>pF1KB7045 476 - 476 aa - 476 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.8607+/-0.000416; mu= -15.3107+/- 0.026 mean_var=587.1766+/-126.777, 0's: 0 Z-trim(125.1): 1394 B-trim: 0 in 0/60 Lambda= 0.052929 statistics sampled from 46335 (48140) to 46335 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.821), E-opt: 0.2 (0.564), width: 16 Scan time: 10.570 The best scores are: opt bits E(85289) NP_001129650 (OMIM: 129010,145900,605253,607678) E ( 476) 3331 268.9 2.2e-71 NP_000390 (OMIM: 129010,145900,605253,607678) E3 S ( 476) 3331 268.9 2.2e-71 NP_001129649 (OMIM: 129010,145900,605253,607678) E ( 476) 3331 268.9 2.2e-71 XP_011537729 (OMIM: 129010,145900,605253,607678) P ( 489) 3225 260.8 6e-69 NP_001129651 (OMIM: 129010,145900,605253,607678) E ( 426) 3007 244.1 5.6e-64 NP_001307966 (OMIM: 129010,145900,605253,607678) E ( 426) 3007 244.1 5.6e-64 NP_001955 (OMIM: 128990) early growth response pro ( 543) 823 77.5 1.1e-13 NP_001186810 (OMIM: 602419) early growth response ( 333) 768 73.0 1.4e-12 NP_001186809 (OMIM: 602419) early growth response ( 349) 768 73.1 1.4e-12 XP_005273483 (OMIM: 602419) PREDICTED: early growt ( 349) 768 73.1 1.4e-12 NP_004421 (OMIM: 602419) early growth response pro ( 387) 768 73.1 1.5e-12 XP_011542731 (OMIM: 602419) PREDICTED: early growt ( 406) 768 73.1 1.6e-12 XP_005273482 (OMIM: 602419) PREDICTED: early growt ( 442) 768 73.2 1.7e-12 NP_001956 (OMIM: 128992) early growth response pro ( 589) 596 60.2 1.8e-08 NP_001263204 (OMIM: 600999) myc-associated zinc fi ( 454) 470 50.4 1.2e-05 XP_006721110 (OMIM: 600999) PREDICTED: myc-associa ( 470) 470 50.4 1.2e-05 NP_002374 (OMIM: 600999) myc-associated zinc finge ( 477) 470 50.5 1.3e-05 NP_001036004 (OMIM: 600999) myc-associated zinc fi ( 493) 470 50.5 1.3e-05 XP_006721111 (OMIM: 600999) PREDICTED: myc-associa ( 401) 431 47.4 8.8e-05 NP_001185480 (OMIM: 106210,136680,156240,194070,19 ( 302) 422 46.6 0.00012 NP_000369 (OMIM: 106210,136680,156240,194070,19407 ( 497) 422 46.8 0.00016 NP_077742 (OMIM: 106210,136680,156240,194070,19407 ( 514) 422 46.8 0.00017 NP_001185481 (OMIM: 106210,136680,156240,194070,19 ( 288) 406 45.3 0.00026 NP_077744 (OMIM: 106210,136680,156240,194070,19407 ( 517) 406 45.6 0.00039 NP_114124 (OMIM: 606139) Krueppel-like factor 16 [ ( 252) 372 42.7 0.0015 NP_008894 (OMIM: 194529) zinc finger protein 22 [H ( 224) 346 40.6 0.0053 NP_003566 (OMIM: 603397) zinc finger protein 282 i ( 671) 357 42.0 0.0063 XP_006716214 (OMIM: 603397) PREDICTED: zinc finger ( 672) 357 42.0 0.0063 NP_619638 (OMIM: 609393) Krueppel-like factor 14 [ ( 323) 344 40.7 0.0076 NP_057354 (OMIM: 602016) Krueppel-like factor 2 [H ( 355) 345 40.8 0.0077 NP_001277013 (OMIM: 612248) zinc finger protein 62 ( 351) 342 40.5 0.0089 NP_001277014 (OMIM: 612248) zinc finger protein 62 ( 351) 342 40.5 0.0089 >>NP_001129650 (OMIM: 129010,145900,605253,607678) E3 SU (476 aa) initn: 3331 init1: 3331 opt: 3331 Z-score: 1402.7 bits: 268.9 E(85289): 2.2e-71 Smith-Waterman score: 3331; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KB7 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH 370 380 390 400 410 420 430 440 450 460 470 pF1KB7 LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 430 440 450 460 470 >>NP_000390 (OMIM: 129010,145900,605253,607678) E3 SUMO- (476 aa) initn: 3331 init1: 3331 opt: 3331 Z-score: 1402.7 bits: 268.9 E(85289): 2.2e-71 Smith-Waterman score: 3331; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KB7 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH 370 380 390 400 410 420 430 440 450 460 470 pF1KB7 LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 430 440 450 460 470 >>NP_001129649 (OMIM: 129010,145900,605253,607678) E3 SU (476 aa) initn: 3331 init1: 3331 opt: 3331 Z-score: 1402.7 bits: 268.9 E(85289): 2.2e-71 Smith-Waterman score: 3331; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KB7 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH 370 380 390 400 410 420 430 440 450 460 470 pF1KB7 LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 430 440 450 460 470 >>XP_011537729 (OMIM: 129010,145900,605253,607678) PREDI (489 aa) initn: 3225 init1: 3225 opt: 3225 Z-score: 1358.8 bits: 260.8 E(85289): 6e-69 Smith-Waterman score: 3225; 99.4% identity (99.8% similar) in 462 aa overlap (15-476:28-489) 10 20 30 40 pF1KB7 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGP ::..: ::::::::::::::::::::::::::: XP_011 MRVGLPSEASSCPWSARGPRDPPERRRSGLAHVLSDNIYPVEDLAATSVTIFPNAELGGP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 FDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 YPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSP 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 PPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYP 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 GFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 GSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGC 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB7 DRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKF 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB7 ARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLA 430 440 450 460 470 480 470 pF1KB7 PCSSRTRTP ::::::::: XP_011 PCSSRTRTP >>NP_001129651 (OMIM: 129010,145900,605253,607678) E3 SU (426 aa) initn: 3007 init1: 3007 opt: 3007 Z-score: 1269.6 bits: 244.1 E(85289): 5.6e-64 Smith-Waterman score: 3007; 100.0% identity (100.0% similar) in 426 aa overlap (51-476:1-426) 30 40 50 60 70 80 pF1KB7 LSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFA :::::::::::::::::::::::::::::: NP_001 MNGVAGDGMINIDMTGEKRSLDLPYPSSFA 10 20 30 90 100 110 120 130 140 pF1KB7 PVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSAS 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB7 PNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB7 AYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPP 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB7 PLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPI 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB7 LRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFS 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB7 RSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPST 340 350 360 370 380 390 450 460 470 pF1KB7 ASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP :::::::::::::::::::::::::::::::::::: NP_001 ASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 400 410 420 >>NP_001307966 (OMIM: 129010,145900,605253,607678) E3 SU (426 aa) initn: 3007 init1: 3007 opt: 3007 Z-score: 1269.6 bits: 244.1 E(85289): 5.6e-64 Smith-Waterman score: 3007; 100.0% identity (100.0% similar) in 426 aa overlap (51-476:1-426) 30 40 50 60 70 80 pF1KB7 LSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFA :::::::::::::::::::::::::::::: NP_001 MNGVAGDGMINIDMTGEKRSLDLPYPSSFA 10 20 30 90 100 110 120 130 140 pF1KB7 PVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSAS 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB7 PNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB7 AYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPP 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB7 PLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPI 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB7 LRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFS 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB7 RSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPST 340 350 360 370 380 390 450 460 470 pF1KB7 ASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP :::::::::::::::::::::::::::::::::::: NP_001 ASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 400 410 420 >>NP_001955 (OMIM: 128990) early growth response protein (543 aa) initn: 896 init1: 708 opt: 823 Z-score: 367.0 bits: 77.5 E(85289): 1.1e-13 Smith-Waterman score: 1019; 43.1% identity (66.7% similar) in 448 aa overlap (32-476:80-469) 10 20 30 40 50 60 pF1KB7 MTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELG-GPFDQMNGVAGDGMI ...: :. :.:. : :.... ..... NP_001 GAAGAPEGSGSNSSSSSSGGGGGGGGGSNSSSSSSTFNPQADTGEQPYEHL---TAESFP 50 60 70 80 90 100 70 80 90 100 110 pF1KB7 NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQ-YPGASCYPEGIINIVSAG .:....:: .. :::. . : .:: :.::..: : . .:: ....:: : NP_001 DISLNNEKVLVETSYPSQ-----TTRLPPITYTGRFSLEPAPNSGNTLWPEPLFSLVS-G 110 120 130 140 150 160 120 130 140 150 160 170 pF1KB7 ILQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPP-PPPYSGCA ... .. :::.... : ...: . . ::. :.. .. : . .:: : : : . NP_001 LVSMTNPPASSSSAPSPAASSASASQSPPLS-CAVPSN--DSSPIYSAAPTFPTPNT--- 170 180 190 200 210 180 190 200 210 220 230 pF1KB7 GDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDL :.. .:.. .: :....: :::: .::. : . . :::::: .::.: : :: NP_001 -DIFPEPQS--QAFPGSAGTALQYPPP-AYPAAKGGFQ---VPMIPDY--LFPQQ-QGDL 220 230 240 250 260 240 250 260 270 280 290 pF1KB7 HGTAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSS : . ::.::: :.. : :::::::. :. ...::. . NP_001 -GLGTPDQKPFQ-GLESRTQQPSLTPLSTIKAFA------------TQSGSQDLK----- 270 280 290 300 300 310 320 330 340 350 pF1KB7 SAAAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELT : ..:. . . .: : ::::::::::: ::::: ::.:.:::::::::::: NP_001 ------ALNTSYQSQLI--KPS-RMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELT 310 320 330 340 350 360 370 380 390 400 410 pF1KB7 RHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTK ::::::::.:::::::::::::::::::::::::::::::::: :::::::::::::::: NP_001 RHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTK 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB7 IHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP ::::::..:.. :: : :.:. : . :. . : : . : .: .. .: NP_001 IHLRQKDKKADK---SVVA-SSATSSLSSYPSPVATSYPSPVTTSYP-SPATTSYPSPVP 420 430 440 450 460 470 NP_001 TSFSSPGSSTYPSPVHSGFPSPSVATTYSSVPPAFPAQVSSFPSSAVTNSFSASTGLSDM 480 490 500 510 520 530 >>NP_001186810 (OMIM: 602419) early growth response prot (333 aa) initn: 1136 init1: 731 opt: 768 Z-score: 346.9 bits: 73.0 E(85289): 1.4e-12 Smith-Waterman score: 1112; 51.5% identity (68.5% similar) in 394 aa overlap (60-444:1-333) 30 40 50 60 70 80 pF1KB7 DLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQT ..: .:.:: . .: : .:: : :: :.: NP_001 MDIGLTNEKPNPELSYSGSFQP--APGNKT 10 20 90 100 110 120 130 140 pF1KB7 FTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPL ::.:::..: :. : ..::...::::: :: ::: . :.....:: .. : NP_001 VTYLGKFAFDS--PSNWCQ-DNIISLMSAGIL-GVP-PASGALSTQTSTAS---MVQPPQ 30 40 50 60 70 80 150 160 170 180 190 200 pF1KB7 GVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYP : :.. .: : ::::.: ::::..: .: . . . .::: : .: NP_001 G---------DVEAMY---PALPPYSNC-GDLYSEPVSFHDP---QGNPGLAYSPQ-DYQ 90 100 110 120 210 220 230 240 250 260 pF1KB7 SPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRV-PPPLTPLSTI : ::: : .:::::::: . . :. :. :..::: .: .:: :::.::: :: NP_001 SAKPALDSNLFPMIPDYNLYHHPN---DM-GSI-PEHKPFQ-GMDPIRVNPPPITPLETI 130 140 150 160 170 270 280 290 300 310 320 pF1KB7 RNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKYPN . : . :: :: :. : : :.:: ::::::: NP_001 KAF-----KDKQIHPGF--GSL-PQPP-------------------LTLKPI-RPRKYPN 180 190 200 330 340 350 360 370 380 pF1KB7 RPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTH ::::::.::::. :::::::::::::::::::.::::::::::::::::.:::::::::: NP_001 RPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTH 210 220 230 240 250 260 390 400 410 420 430 440 pF1KB7 IRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKS---SAPSAS-VP----APST ::::::::::::..::::::::::::::.::::.:::.:. .::::: .: :: . NP_001 IRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAPVV 270 280 290 300 310 320 450 460 470 pF1KB7 ASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP ..:. NP_001 TTCA 330 >>NP_001186809 (OMIM: 602419) early growth response prot (349 aa) initn: 1136 init1: 731 opt: 768 Z-score: 346.6 bits: 73.1 E(85289): 1.4e-12 Smith-Waterman score: 1115; 51.3% identity (68.8% similar) in 398 aa overlap (57-444:14-349) 30 40 50 60 70 80 pF1KB7 PVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPR .....: .:.:: . .: : .:: : :: NP_001 MEPCAAWSPRGGRENVMDIGLTNEKPNPELSYSGSFQP--APG 10 20 30 40 90 100 110 120 130 140 pF1KB7 NQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLAT :.: ::.:::..: :. : ..::...::::: :: ::: . :.....:: .. NP_001 NKTVTYLGKFAFDS--PSNWCQ-DNIISLMSAGIL-GVP-PASGALSTQTSTAS---MVQ 50 60 70 80 90 150 160 170 180 190 200 pF1KB7 GPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPP : : :.. .: : ::::.: ::::..: .: . . . .::: : NP_001 PPQG---------DVEAMY---PALPPYSNC-GDLYSEPVSFHD---PQGNPGLAYSPQ- 100 110 120 130 210 220 230 240 250 260 pF1KB7 SYPSPKPATDPGLFPMIPDYPGFF-PSQCQRDLHGTAGPDRKPFPCPLDTLRV-PPPLTP .: : ::: : .:::::::: . :. :. :. :..::: .: .:: :::.:: NP_001 DYQSAKPALDSNLFPMIPDYNLYHHPN----DM-GSI-PEHKPFQ-GMDPIRVNPPPITP 140 150 160 170 180 270 280 290 300 310 320 pF1KB7 LSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPR : ::. : . :: :: :. : : :.:: ::: NP_001 LETIKAF-----KDKQIHPGF--GSL-PQPP-------------------LTLKPI-RPR 190 200 210 220 330 340 350 360 370 380 pF1KB7 KYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDH ::::::::::.::::. :::::::::::::::::::.::::::::::::::::.:::::: NP_001 KYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDH 230 240 250 260 270 280 390 400 410 420 430 pF1KB7 LTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKS---SAPSAS-VP---- ::::::::::::::::..::::::::::::::.::::.:::.:. .::::: .: NP_001 LTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSL 290 300 310 320 330 340 440 450 460 470 pF1KB7 APSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP :: ...:. NP_001 APVVTTCA >>XP_005273483 (OMIM: 602419) PREDICTED: early growth re (349 aa) initn: 1136 init1: 731 opt: 768 Z-score: 346.6 bits: 73.1 E(85289): 1.4e-12 Smith-Waterman score: 1115; 51.3% identity (68.8% similar) in 398 aa overlap (57-444:14-349) 30 40 50 60 70 80 pF1KB7 PVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPR .....: .:.:: . .: : .:: : :: XP_005 MEPCAAWSPRGGRENVMDIGLTNEKPNPELSYSGSFQP--APG 10 20 30 40 90 100 110 120 130 140 pF1KB7 NQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLAT :.: ::.:::..: :. : ..::...::::: :: ::: . :.....:: .. XP_005 NKTVTYLGKFAFDS--PSNWCQ-DNIISLMSAGIL-GVP-PASGALSTQTSTAS---MVQ 50 60 70 80 90 150 160 170 180 190 200 pF1KB7 GPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPP : : :.. .: : ::::.: ::::..: .: . . . .::: : XP_005 PPQG---------DVEAMY---PALPPYSNC-GDLYSEPVSFHD---PQGNPGLAYSPQ- 100 110 120 130 210 220 230 240 250 260 pF1KB7 SYPSPKPATDPGLFPMIPDYPGFF-PSQCQRDLHGTAGPDRKPFPCPLDTLRV-PPPLTP .: : ::: : .:::::::: . :. :. :. :..::: .: .:: :::.:: XP_005 DYQSAKPALDSNLFPMIPDYNLYHHPN----DM-GSI-PEHKPFQ-GMDPIRVNPPPITP 140 150 160 170 180 270 280 290 300 310 320 pF1KB7 LSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPR : ::. : . :: :: :. : : :.:: ::: XP_005 LETIKAF-----KDKQIHPGF--GSL-PQPP-------------------LTLKPI-RPR 190 200 210 220 330 340 350 360 370 380 pF1KB7 KYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDH ::::::::::.::::. :::::::::::::::::::.::::::::::::::::.:::::: XP_005 KYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDH 230 240 250 260 270 280 390 400 410 420 430 pF1KB7 LTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKS---SAPSAS-VP---- ::::::::::::::::..::::::::::::::.::::.:::.:. .::::: .: XP_005 LTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSL 290 300 310 320 330 340 440 450 460 470 pF1KB7 APSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP :: ...:. XP_005 APVVTTCA 476 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:13:09 2016 done: Fri Nov 4 04:13:10 2016 Total Scan time: 10.570 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]