FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7047, 490 aa 1>>>pF1KB7047 490 - 490 aa - 490 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4914+/-0.00043; mu= 12.8316+/- 0.027 mean_var=103.5591+/-21.164, 0's: 0 Z-trim(112.1): 66 B-trim: 1023 in 1/51 Lambda= 0.126032 statistics sampled from 20867 (20931) to 20867 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.245), width: 16 Scan time: 9.310 The best scores are: opt bits E(85289) NP_001026853 (OMIM: 604650) interferon-induced pro ( 490) 3264 604.6 2.1e-172 NP_001540 (OMIM: 604650) interferon-induced protei ( 490) 3264 604.6 2.1e-172 NP_001276688 (OMIM: 604650) interferon-induced pro ( 438) 2918 541.6 1.6e-153 NP_001276687 (OMIM: 604650) interferon-induced pro ( 438) 2918 541.6 1.6e-153 NP_001538 (OMIM: 147040) interferon-induced protei ( 472) 1438 272.5 1.8e-72 NP_036552 (OMIM: 616135) interferon-induced protei ( 482) 1098 210.7 7.4e-54 NP_001539 (OMIM: 147690) interferon-induced protei ( 478) 740 145.6 2.9e-34 NP_001257856 (OMIM: 147690) interferon-induced pro ( 478) 740 145.6 2.9e-34 NP_001257858 (OMIM: 147690) interferon-induced pro ( 447) 667 132.3 2.7e-30 NP_001257857 (OMIM: 147690) interferon-induced pro ( 447) 667 132.3 2.7e-30 NP_001257859 (OMIM: 147690) interferon-induced pro ( 447) 667 132.3 2.7e-30 >>NP_001026853 (OMIM: 604650) interferon-induced protein (490 aa) initn: 3264 init1: 3264 opt: 3264 Z-score: 3216.3 bits: 604.6 E(85289): 2.1e-172 Smith-Waterman score: 3264; 100.0% identity (100.0% similar) in 490 aa overlap (1-490:1-490) 10 20 30 40 50 60 pF1KB7 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR 430 440 450 460 470 480 490 pF1KB7 ELLSNSEQLN :::::::::: NP_001 ELLSNSEQLN 490 >>NP_001540 (OMIM: 604650) interferon-induced protein wi (490 aa) initn: 3264 init1: 3264 opt: 3264 Z-score: 3216.3 bits: 604.6 E(85289): 2.1e-172 Smith-Waterman score: 3264; 100.0% identity (100.0% similar) in 490 aa overlap (1-490:1-490) 10 20 30 40 50 60 pF1KB7 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR 430 440 450 460 470 480 490 pF1KB7 ELLSNSEQLN :::::::::: NP_001 ELLSNSEQLN 490 >>NP_001276688 (OMIM: 604650) interferon-induced protein (438 aa) initn: 2918 init1: 2918 opt: 2918 Z-score: 2877.0 bits: 541.6 E(85289): 1.6e-153 Smith-Waterman score: 2918; 100.0% identity (100.0% similar) in 438 aa overlap (53-490:1-438) 30 40 50 60 70 80 pF1KB7 NLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDGNNEAALECLRQAEELIQ :::::::::::::::::::::::::::::: NP_001 MYNLLAYIKHLDGNNEAALECLRQAEELIQ 10 20 30 90 100 110 120 130 140 pF1KB7 QEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB7 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB7 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB7 LFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKAL 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB7 EKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHG 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB7 LEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGLIHKQNGDLLQAAKCYEKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGLIHKQNGDLLQAAKCYEKEL 340 350 360 370 380 390 450 460 470 480 490 pF1KB7 GRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN 400 410 420 430 >>NP_001276687 (OMIM: 604650) interferon-induced protein (438 aa) initn: 2918 init1: 2918 opt: 2918 Z-score: 2877.0 bits: 541.6 E(85289): 1.6e-153 Smith-Waterman score: 2918; 100.0% identity (100.0% similar) in 438 aa overlap (53-490:1-438) 30 40 50 60 70 80 pF1KB7 NLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDGNNEAALECLRQAEELIQ :::::::::::::::::::::::::::::: NP_001 MYNLLAYIKHLDGNNEAALECLRQAEELIQ 10 20 30 90 100 110 120 130 140 pF1KB7 QEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB7 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB7 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB7 LFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKAL 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB7 EKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHG 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB7 LEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGLIHKQNGDLLQAAKCYEKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGLIHKQNGDLLQAAKCYEKEL 340 350 360 370 380 390 450 460 470 480 490 pF1KB7 GRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN 400 410 420 430 >>NP_001538 (OMIM: 147040) interferon-induced protein wi (472 aa) initn: 1271 init1: 785 opt: 1438 Z-score: 1422.1 bits: 272.5 E(85289): 1.8e-72 Smith-Waterman score: 1624; 57.4% identity (77.3% similar) in 472 aa overlap (1-454:1-471) 10 20 30 40 50 60 pF1KB7 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI ::: .:::::. : ::::::::::.. .. :.::.: . :: : :::::: :::::. NP_001 MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV ::: :.:::::::::.::::::::::::::::::::::::::::::.:::::.::::::: NP_001 KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 KQTCKKFSNPYSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSGLAI :..:.:::.:: :: :::::::::.:::: .:::::::::::::.::.::::.::::: NP_001 KHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 AMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKM----NKEAEGEQFVEEAL : :.::: : .: . : :.:::.:.:::::.::::.:::.:: ..:.:::..::::: NP_001 ASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEAL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB7 EKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQN ::.: :::::::::::::: . ::::::....:: :::.::. ::::::.::: :..: NP_001 EKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMN 250 260 270 280 290 300 300 310 320 330 340 pF1KB7 TGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLA-------EFLETECY-QT :. :.....: : .:. . .:: : . : . . : :: .. ..: : : NP_001 LRENGMYGKRKLLE-LIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQK 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 PFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVS :.::. . :: : :: :.: :. : :: :..: .::..:..:: .::..::. :... NP_001 EFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIA 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB7 ENLLPQNAPNYWYLQGLIHKQ--NGDLLQAAKCYEK--ELGRLLRDAPSGIGSIFLSASE . : .:. . :. : : : . :: . :. : : :. .: : : NP_001 KMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE 420 430 440 450 460 470 470 480 490 pF1KB7 LEDGSEEMGQGAVSSSPRELLSNSEQLN >>NP_036552 (OMIM: 616135) interferon-induced protein wi (482 aa) initn: 1201 init1: 555 opt: 1098 Z-score: 1087.9 bits: 210.7 E(85289): 7.4e-54 Smith-Waterman score: 1264; 44.3% identity (75.0% similar) in 460 aa overlap (1-440:1-460) 10 20 30 40 50 60 pF1KB7 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI :::. :..:. :: .:.:::::::.::: ..:: . .:.:::.:. . ..::::::. NP_036 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV ::: :.:. :::::.::::.:::::.:. :.:::::::::::::::. .: .:: :. :. NP_036 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 KQTCKKFSNP--YSIEYSELDCEEGWTQLKCGRN--ERAKVCFEKALEEKPNNPEFSSGL ..:::.:.: :..: : :::.::. :: : . ..::. :::::: .:.::::. : NP_036 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 AIAMYHLDNHPE----KQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEE ::..:.::. . :.:: :..:. :.:::.:.::.:.:::: .. :::::...:: NP_036 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB7 ALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQM :.. : ::: ::::::::.. .::.::....:: ::....:.::.: ::.:.. :. NP_036 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 250 260 270 280 290 300 300 310 320 330 340 pF1KB7 QNTGESEASGNKEM-IEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLETECYQTP--- ... ... .:. .. .. : . :. . . :.:. ::.:::. . : :.. NP_036 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB7 FNK-----EVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQP : : .. : .:.: : .: .:... :::.::..: ::.:... .: . .. . NP_036 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB7 QNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSA ...: . : .:: . :. :...: .:. :::. ::: NP_036 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 430 440 450 460 470 480 470 480 490 pF1KB7 SELEDGSEEMGQGAVSSSPRELLSNSEQLN NP_036 SI >>NP_001539 (OMIM: 147690) interferon-induced protein wi (478 aa) initn: 1028 init1: 527 opt: 740 Z-score: 736.2 bits: 145.6 E(85289): 2.9e-34 Smith-Waterman score: 1225; 44.6% identity (73.0% similar) in 471 aa overlap (6-453:11-474) 10 20 30 40 50 pF1KB7 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYN :.::: ::.:::::.: .:. :::.:: .:::::.:.... ..: NP_001 MSTNGDDHQVKDSLE----QLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHN 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQI ::::.::: :.:: ::. :..::.:.:.:: .::..::::::::.::.:::.:::..:: NP_001 LLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YVDKVKQTCKKFSNP--YSIEYSELDCEEGWTQLKCG-RN-ERAKVCFEKALEEKPNNPE :.:::.. :::.::: : .: :.::::::. :::: .: ::::.::::.:: :.::: NP_001 YLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPE 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 FSSGLAIAMYHLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEA :.: ::. :.:: :: : :: :.::..:.::: :.::::.:::: ..:: NP_001 SSAGYAISAYRLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 EGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCC :::...:::: . :: :.: :::::::::..:::.::....:. ::.. :.:::: : NP_001 EGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLC 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 YKAKVRQMQNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLET- :::.. :.... ... : :.: .. . . :. . ..:.:: . :. :::. ..:. NP_001 YKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAG 300 310 320 330 340 350 350 360 370 380 390 pF1KB7 ------ECYQTPFN-KEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTD : .: . : : . :. : .: .:... ::. .:. : :....: . : NP_001 NHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLT 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB7 KEEIKDQPQNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSG ... .. ... : ..: . :. :...: .:.. .: . ::. : :: : .. NP_001 RDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENS 420 430 440 450 460 470 460 470 480 490 pF1KB7 IGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN . NP_001 VRQGP >>NP_001257856 (OMIM: 147690) interferon-induced protein (478 aa) initn: 1028 init1: 527 opt: 740 Z-score: 736.2 bits: 145.6 E(85289): 2.9e-34 Smith-Waterman score: 1225; 44.6% identity (73.0% similar) in 471 aa overlap (6-453:11-474) 10 20 30 40 50 pF1KB7 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYN :.::: ::.:::::.: .:. :::.:: .:::::.:.... ..: NP_001 MCTNGDDHQVKDSLE----QLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHN 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQI ::::.::: :.:: ::. :..::.:.:.:: .::..::::::::.::.:::.:::..:: NP_001 LLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YVDKVKQTCKKFSNP--YSIEYSELDCEEGWTQLKCG-RN-ERAKVCFEKALEEKPNNPE :.:::.. :::.::: : .: :.::::::. :::: .: ::::.::::.:: :.::: NP_001 YLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPE 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 FSSGLAIAMYHLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEA :.: ::. :.:: :: : :: :.::..:.::: :.::::.:::: ..:: NP_001 SSAGYAISAYRLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 EGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCC :::...:::: . :: :.: :::::::::..:::.::....:. ::.. :.:::: : NP_001 EGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLC 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 YKAKVRQMQNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLET- :::.. :.... ... : :.: .. . . :. . ..:.:: . :. :::. ..:. NP_001 YKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAG 300 310 320 330 340 350 350 360 370 380 390 pF1KB7 ------ECYQTPFN-KEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTD : .: . : : . :. : .: .:... ::. .:. : :....: . : NP_001 NHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLT 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB7 KEEIKDQPQNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSG ... .. ... : ..: . :. :...: .:.. .: . ::. : :: : .. NP_001 RDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENS 420 430 440 450 460 470 460 470 480 490 pF1KB7 IGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN . NP_001 VRQGP >>NP_001257858 (OMIM: 147690) interferon-induced protein (447 aa) initn: 957 init1: 456 opt: 667 Z-score: 664.9 bits: 132.3 E(85289): 2.7e-30 Smith-Waterman score: 1152; 44.4% identity (73.4% similar) in 444 aa overlap (33-453:3-443) 10 20 30 40 50 60 pF1KB7 EVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKH :::.:: .:::::.:.... ..:::::.:: NP_001 MPDLENRVLDQIEFLDTKYSVGIHNLLAYVKH 10 20 30 70 80 90 100 110 120 pF1KB7 LDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQ : :.:: ::. :..::.:.:.:: .::..::::::::.::.:::.:::..:: :.:::.. NP_001 LKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVEN 40 50 60 70 80 90 130 140 150 160 170 pF1KB7 TCKKFSNP--YSIEYSELDCEEGWTQLKCG-RN-ERAKVCFEKALEEKPNNPEFSSGLAI :::.::: : .: :.::::::. :::: .: ::::.::::.:: :.::: :.: :: NP_001 ICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAI 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 AMYHLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVE . :.:: :: : :: :.::..:.::: :.::::.:::: ..:::::...: NP_001 SAYRLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIE 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB7 EALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQ ::: . :: :.: :::::::::..:::.::....:. ::.. :.:::: ::::.. : NP_001 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQ 220 230 240 250 260 270 300 310 320 330 340 pF1KB7 MQNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLET-------E .... ... : :.: .. . . :. . ..:.:: . :. :::. ..:. : NP_001 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 CYQTPFN-KEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQ .: . : : . :. : .: .:... ::. .:. : :....: . : ... .. NP_001 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS 340 350 360 370 380 390 410 420 430 440 450 pF1KB7 PQNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLS ... : ..: . :. :...: .:.. .: . ::. : :: : ... NP_001 LKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENSVRQGP 400 410 420 430 440 460 470 480 490 pF1KB7 ASELEDGSEEMGQGAVSSSPRELLSNSEQLN >>NP_001257857 (OMIM: 147690) interferon-induced protein (447 aa) initn: 957 init1: 456 opt: 667 Z-score: 664.9 bits: 132.3 E(85289): 2.7e-30 Smith-Waterman score: 1152; 44.4% identity (73.4% similar) in 444 aa overlap (33-453:3-443) 10 20 30 40 50 60 pF1KB7 EVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKH :::.:: .:::::.:.... ..:::::.:: NP_001 MPDLENRVLDQIEFLDTKYSVGIHNLLAYVKH 10 20 30 70 80 90 100 110 120 pF1KB7 LDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQ : :.:: ::. :..::.:.:.:: .::..::::::::.::.:::.:::..:: :.:::.. NP_001 LKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVEN 40 50 60 70 80 90 130 140 150 160 170 pF1KB7 TCKKFSNP--YSIEYSELDCEEGWTQLKCG-RN-ERAKVCFEKALEEKPNNPEFSSGLAI :::.::: : .: :.::::::. :::: .: ::::.::::.:: :.::: :.: :: NP_001 ICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAI 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 AMYHLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVE . :.:: :: : :: :.::..:.::: :.::::.:::: ..:::::...: NP_001 SAYRLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIE 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB7 EALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQ ::: . :: :.: :::::::::..:::.::....:. ::.. :.:::: ::::.. : NP_001 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQ 220 230 240 250 260 270 300 310 320 330 340 pF1KB7 MQNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLET-------E .... ... : :.: .. . . :. . ..:.:: . :. :::. ..:. : NP_001 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE 280 290 300 310 320 330 350 360 370 380 390 400 pF1KB7 CYQTPFN-KEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQ .: . : : . :. : .: .:... ::. .:. : :....: . : ... .. NP_001 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINS 340 350 360 370 380 390 410 420 430 440 450 pF1KB7 PQNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLS ... : ..: . :. :...: .:.. .: . ::. : :: : ... NP_001 LKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENSVRQGP 400 410 420 430 440 460 470 480 490 pF1KB7 ASELEDGSEEMGQGAVSSSPRELLSNSEQLN 490 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:13:46 2016 done: Fri Nov 4 04:13:47 2016 Total Scan time: 9.310 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]