FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7050, 504 aa 1>>>pF1KB7050 504 - 504 aa - 504 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2028+/-0.000792; mu= 8.1684+/- 0.048 mean_var=208.5540+/-42.210, 0's: 0 Z-trim(116.2): 17 B-trim: 0 in 0/51 Lambda= 0.088811 statistics sampled from 16827 (16838) to 16827 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.517), width: 16 Scan time: 4.150 The best scores are: opt bits E(32554) CCDS6514.1 DMRTA1 gene_id:63951|Hs108|chr9 ( 504) 3410 449.1 5.4e-126 CCDS44141.1 DMRTA2 gene_id:63950|Hs108|chr1 ( 542) 513 77.9 3.1e-14 CCDS6442.1 DMRT1 gene_id:1761|Hs108|chr9 ( 373) 435 67.8 2.4e-11 >>CCDS6514.1 DMRTA1 gene_id:63951|Hs108|chr9 (504 aa) initn: 3410 init1: 3410 opt: 3410 Z-score: 2375.4 bits: 449.1 E(32554): 5.4e-126 Smith-Waterman score: 3410; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504) 10 20 30 40 50 60 pF1KB7 MERSQCGSRDRGVSGRPHLAPGLVVAAPPPPSPALPVPSGMQVPPAFLRPPSLFLRAAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MERSQCGSRDRGVSGRPHLAPGLVVAAPPPPSPALPVPSGMQVPPAFLRPPSLFLRAAAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AAAAAAATSGSGGCPPAPGLESGVGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 AAAAAAATSGSGGCPPAPGLESGVGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQRLLCSGLSWPPGGRASGGGGRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQRLLCSGLSWPPGGRASGGGGRAE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 NPQSTGGPAAGAALGLGALRQASGSATPAFEVFQQDYPEEKQEQKESKCESCQNGQEELI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 NPQSTGGPAAGAALGLGALRQASGSATPAFEVFQQDYPEEKQEQKESKCESCQNGQEELI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 SKSHQLYLGSSSRSNGVIGKQSIGSSISEYSNKPDSILSPHPGEQSGGEESPRSLSSSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 SKSHQLYLGSSSRSNGVIGKQSIGSSISEYSNKPDSILSPHPGEQSGGEESPRSLSSSDL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 ESGNESEWVKDLTATKASLPTVSSRPRDPLDILTKIFPNYRRSRLEGILRFCKGDVVQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 ESGNESEWVKDLTATKASLPTVSSRPRDPLDILTKIFPNYRRSRLEGILRFCKGDVVQAI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 EQVLNGKEHKPDNRNLANSEELENTAFQRASSFSLAGIGFGTLGNKSAFSPLQTTSASYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 EQVLNGKEHKPDNRNLANSEELENTAFQRASSFSLAGIGFGTLGNKSAFSPLQTTSASYG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 GDSSLYGVNPRVGISPLRLAYSSAGRGLSGFMSPYLTPGLVPTLPFRPALDYAFSGMIRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 GDSSLYGVNPRVGISPLRLAYSSAGRGLSGFMSPYLTPGLVPTLPFRPALDYAFSGMIRD 430 440 450 460 470 480 490 500 pF1KB7 SSYLSSKDSITCGRLYFRPNQDNP :::::::::::::::::::::::: CCDS65 SSYLSSKDSITCGRLYFRPNQDNP 490 500 >>CCDS44141.1 DMRTA2 gene_id:63950|Hs108|chr1 (542 aa) initn: 956 init1: 462 opt: 513 Z-score: 369.0 bits: 77.9 E(32554): 3.1e-14 Smith-Waterman score: 941; 40.5% identity (59.9% similar) in 516 aa overlap (28-478:8-509) 10 20 30 40 50 60 pF1KB7 MERSQCGSRDRGVSGRPHLAPGLVVAAPPPPSPALPVPSGMQVPPAFLRPPSLFLRAAAA : :. : . . ::. :. :::: CCDS44 MELRSELPSVPGAATAAAATATGPPV----ASVASVAAAA 10 20 30 70 80 90 100 110 120 pF1KB7 AAAAAAATSGSGGCPPAPGLESGVGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRD ::::. .: .:: .: : . .. ::::::::::::::::::::::::.:::.: CCDS44 AAAASLPVSVAGGLLRGPPL---LLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKD 40 50 60 70 80 90 130 140 150 160 pF1KB7 CACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQRLLCS--GLSW-------PP--- : ::::::::::::::::::::::::::::.::: :: : . ::. :: CCDS44 CLCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPA 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB7 ----GG--RASGGGGRAENPQSTGGPAAGAALGLGALRQASGSATPAFEVFQQDYPEEKQ :. :.::: : : .::: ::::. . . :.. . ... . : CCDS44 YEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPP 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB7 EQKESKCESCQNGQEELISKSHQLYLGSSSRSNGVIGKQSIGSSISEYSNKPDSILSPHP . : .. ..: ..: .. ::.:. :: :.. :: ... :.. . CCDS44 VKPLSP-DGADSGPG---TSSPEVRPGSGSE-NGD-GESFSGSPLARASKEAGGSCPGSA 220 230 240 250 260 290 300 310 320 330 340 pF1KB7 GEQSGGEE-SPRSLSSSDLESGNESEWVKDLTATKASLPTVSS-RPRDPLDILTKIFPNY : .:::: :: : : :::.:.. . .: .: :. : : ::::::..::.. CCDS44 GPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGH 270 280 290 300 310 320 350 360 370 380 390 pF1KB7 RRSRLEGILRFCKGDVVQAIEQVLN----------GKEHKPDNRNLANSEELENTAFQRA ::. :: .:. : :::::::::::: : ::. .. . ... .:. CCDS44 RRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRV 330 340 350 360 370 380 400 410 pF1KB7 SSFS----------------------------LAGI----GFGTLGNKSAFSPLQTTSAS .. . ::: ..:.:...::::::: ... CCDS44 DAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASH 390 400 410 420 430 440 420 430 440 450 460 470 pF1KB7 YGGDSSLYGVNPRVGISPLRLAYSSAG---RGLSGFMSPYLTPGLVPTLPFRPALDYAFS .:.:.. : .. .:.::::::::.:. :::. ::.:: : :::::: ::: .::::: CCDS44 FGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLA-FMAPYSTAGLVPTLGFRPPMDYAFS 450 460 470 480 490 500 480 490 500 pF1KB7 GMIRDSSYLSSKDSITCGRLYFRPNQDNP .. CCDS44 DLMRDRSAAAAAAVHKEPTYGGGLYGPMVNGAPEKQ 510 520 530 540 >>CCDS6442.1 DMRT1 gene_id:1761|Hs108|chr9 (373 aa) initn: 442 init1: 407 opt: 435 Z-score: 317.1 bits: 67.8 E(32554): 2.4e-11 Smith-Waterman score: 435; 57.9% identity (71.4% similar) in 126 aa overlap (28-150:10-129) 10 20 30 40 50 60 pF1KB7 MERSQCGSRDRGVSGRPHLAPGLVVAAPPPPSPALPVPSGMQVPPAFLRPPSLFLRAAAA : :: : : . ::: : . : .:..: CCDS64 MPNDEAFSKPSTPSEA---PHAPGVPPQG-RAGG-FGKASGA 10 20 30 70 80 90 100 110 pF1KB7 AAAAAAATSGSGGCPPAPGLESGVGAVGCGY---PRTPKCARCRNHGVVSALKGHKRFCR ..::...: .:: . : ::.. .: : :: :::::::::: .: :::::::: CCDS64 LVGAASGSS-AGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKRFCM 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB7 WRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQRLLCSGLSWPPGGRASGGGG :::: : ::.::::::::::::::::::::::: CCDS64 WRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNP 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 RAENPQSTGGPAAGAALGLGALRQASGSATPAFEVFQQDYPEEKQEQKESKCESCQNGQE CCDS64 CLMTECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENTPDLVSDSTYYSSFYQP 160 170 180 190 200 210 504 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:14:49 2016 done: Fri Nov 4 04:14:50 2016 Total Scan time: 4.150 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]