FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7055, 582 aa 1>>>pF1KB7055 582 - 582 aa - 582 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4261+/-0.000532; mu= -1.2974+/- 0.033 mean_var=208.8796+/-43.767, 0's: 0 Z-trim(112.9): 21 B-trim: 0 in 0/54 Lambda= 0.088741 statistics sampled from 21955 (21971) to 21955 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.258), width: 16 Scan time: 9.100 The best scores are: opt bits E(85289) NP_002999 (OMIM: 182141) semenogelin-2 precursor [ ( 582) 3849 506.4 1e-142 NP_002998 (OMIM: 182140) semenogelin-1 preproprote ( 462) 2134 286.8 1.1e-76 >>NP_002999 (OMIM: 182141) semenogelin-2 precursor [Homo (582 aa) initn: 3849 init1: 3849 opt: 3849 Z-score: 2683.1 bits: 506.4 E(85289): 1e-142 Smith-Waterman score: 3849; 99.7% identity (100.0% similar) in 582 aa overlap (1-582:1-582) 10 20 30 40 50 60 pF1KB7 MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGKKGQHYFGQKDQQHTKSK ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: NP_002 MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 AHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLNQDQEHGRKAHKISYPSSRTEERQLHH :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: NP_002 AHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEHGRKAHKISYPSSRTEERQLHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 GEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 GEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 GGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSH 490 500 510 520 530 540 550 560 570 580 pF1KB7 EQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIST :::::::::::::::::::::::::::::::::::::::::: NP_002 EQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIST 550 560 570 580 >>NP_002998 (OMIM: 182140) semenogelin-1 preproprotein [ (462 aa) initn: 2968 init1: 2116 opt: 2134 Z-score: 1498.0 bits: 286.8 E(85289): 1.1e-76 Smith-Waterman score: 2155; 62.2% identity (73.0% similar) in 582 aa overlap (1-582:1-462) 10 20 30 40 50 60 pF1KB7 MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGKKGQHYFGQKDQQHTKSK :: :.::::::::::::::::::::::::.::: ::::::.::::: ::: .:.:.:: NP_002 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSK ::::::.::::: :::: .:::::::::::::.:::..:::::::::. ::::::::::: NP_002 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASG :::: .:::::::.::.:::::::::::::::::.::: ::::.:::::::::::.:.:: NP_002 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHP ::::: ::::::::::::::::.:::::::::::::::::::::.::::::::.:::: : NP_002 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 AHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLNQDQEHGRKAHKISYPSSRTEERQLHH ::::.:::: ::::.::::::::::::::::::::::.:::::.:::: :: ::::.::. NP_002 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNC ::..::::::..:: :. NP_002 GENGVQKDVSQSSI---------------------------------YS----------- 310 370 380 390 400 410 420 pF1KB7 GEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNS NP_002 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KB7 GEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNY ::::: .::::.:.:::::.:::..: ::.::::::::::::.: NP_002 ----------------QTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY 320 330 340 350 360 490 500 510 520 530 540 pF1KB7 GGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSH : ...:::::: :: : :::: ::::::.:::.:. : :.::::.::::.. .:::::: NP_002 GENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 370 380 390 400 410 420 550 560 570 580 pF1KB7 EQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIST :::::... : . .::: :.: .: ::.:. :.::::. : NP_002 EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT 430 440 450 460 582 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:18:35 2016 done: Fri Nov 4 04:18:36 2016 Total Scan time: 9.100 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]