FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7064, 674 aa 1>>>pF1KB7064 674 - 674 aa - 674 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.3564+/-0.000327; mu= -3.2018+/- 0.021 mean_var=255.3756+/-50.497, 0's: 0 Z-trim(124.4): 41 B-trim: 95 in 2/56 Lambda= 0.080257 statistics sampled from 45912 (45958) to 45912 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.539), width: 16 Scan time: 11.800 The best scores are: opt bits E(85289) NP_055145 (OMIM: 611048) protein phosphatase 1 reg ( 674) 4653 551.8 2.9e-156 NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] ( 710) 262 43.4 0.0035 >>NP_055145 (OMIM: 611048) protein phosphatase 1 regulat (674 aa) initn: 4653 init1: 4653 opt: 4653 Z-score: 2926.3 bits: 551.8 E(85289): 2.9e-156 Smith-Waterman score: 4653; 100.0% identity (100.0% similar) in 674 aa overlap (1-674:1-674) 10 20 30 40 50 60 pF1KB7 MAPGQAPHQATPWRDAHPFFLLSPVMGLLSRAWSRLRGLGPLEPWLVEAVKGAALVEAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAPGQAPHQATPWRDAHPFFLLSPVMGLLSRAWSRLRGLGPLEPWLVEAVKGAALVEAGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 REATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 REATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 SWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 DSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 STPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 STPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 GWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPET 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB7 PTHDPDPETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PTHDPDPETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB7 EELSPCLTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EELSPCLTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSS 610 620 630 640 650 660 670 pF1KB7 AAAAAALDLSGRRG :::::::::::::: NP_055 AAAAAALDLSGRRG 670 >>NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] (710 aa) initn: 599 init1: 182 opt: 262 Z-score: 178.2 bits: 43.4 E(85289): 0.0035 Smith-Waterman score: 266; 26.6% identity (52.8% similar) in 305 aa overlap (176-476:16-280) 150 160 170 180 190 200 pF1KB7 LLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHR :.. ::.. : :. .::: . : NP_005 MVKLAKAGKNQGDPKKMAPPPKEVE-----EDSEDEEMSEDEEDD 10 20 30 40 210 220 230 240 250 260 pF1KB7 TSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSP-RSSGSDPRSWEYRS .: . .: . .. . .. .. :.. . :.:..:.: ..... : . NP_005 SSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTP 50 60 70 80 90 100 270 280 290 300 310 320 pF1KB7 GEASEEKEEKAHKETGKGEAA-PGPQSSA-PAQRPQL-KSWWCQPSDEEEGEVKALGAAE ..: .:. ::. .: :: ...: ::. . :. . ::::: . . . NP_005 AKAVTTPGKKG-ATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEED 110 120 130 140 150 330 340 350 360 370 380 pF1KB7 KDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPA . : : : : : .:: . :. . :..::.:.:::.:. ..:...: :: .::: NP_005 DEDEDEDEDEIEP--AAMKAAAAAPASEDEDDEDDEDDEDDDD-DEEDDSEEEAMETTPA 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB7 TGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTE : . : .... :.:::. : ::: .: . NP_005 KGKKAAKVVPVKAKNVAEDEDEEEDD---EDE------------------------DDDD 220 230 240 450 460 470 480 490 500 pF1KB7 EEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGE .:.::: :.:: :.. : : : .: : .: NP_005 DEDDEDDDDEDDEEEEE----EEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTT 250 260 270 280 290 300 510 520 530 540 550 560 pF1KB7 AEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKVRFSEK NP_005 AFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALE 310 320 330 340 350 360 674 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:10:12 2016 done: Sat Nov 5 01:10:13 2016 Total Scan time: 11.800 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]