FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7085, 129 aa 1>>>pF1KB7085 129 - 129 aa - 129 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.3965+/-0.000298; mu= 15.3597+/- 0.019 mean_var=52.0315+/-10.489, 0's: 0 Z-trim(115.9): 20 B-trim: 203 in 1/52 Lambda= 0.177804 statistics sampled from 26628 (26648) to 26628 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.312), width: 16 Scan time: 4.850 The best scores are: opt bits E(85289) NP_001257331 (OMIM: 176261,612347,613695) potassiu ( 129) 847 224.4 4e-59 NP_001257332 (OMIM: 176261,612347,613695) potassiu ( 129) 847 224.4 4e-59 NP_001257334 (OMIM: 176261,612347,613695) potassiu ( 129) 847 224.4 4e-59 NP_001121141 (OMIM: 176261,612347,613695) potassiu ( 129) 847 224.4 4e-59 NP_001257333 (OMIM: 176261,612347,613695) potassiu ( 129) 847 224.4 4e-59 NP_001121142 (OMIM: 176261,612347,613695) potassiu ( 129) 847 224.4 4e-59 NP_001121140 (OMIM: 176261,612347,613695) potassiu ( 129) 847 224.4 4e-59 NP_000210 (OMIM: 176261,612347,613695) potassium v ( 129) 847 224.4 4e-59 XP_016883831 (OMIM: 176261,612347,613695) PREDICTE ( 150) 847 224.4 4.5e-59 NP_751951 (OMIM: 603796,611493,613693) potassium v ( 123) 169 50.4 8.8e-07 NP_542402 (OMIM: 607775) potassium voltage-gated c ( 221) 135 41.9 0.00059 XP_016872538 (OMIM: 604433,613119) PREDICTED: pota ( 103) 116 36.8 0.0095 NP_005463 (OMIM: 604433,613119) potassium voltage- ( 103) 116 36.8 0.0095 XP_016872536 (OMIM: 604433,613119) PREDICTED: pota ( 103) 116 36.8 0.0095 XP_016872537 (OMIM: 604433,613119) PREDICTED: pota ( 103) 116 36.8 0.0095 XP_016872539 (OMIM: 604433,613119) PREDICTED: pota ( 103) 116 36.8 0.0095 XP_016872541 (OMIM: 604433,613119) PREDICTED: pota ( 103) 116 36.8 0.0095 XP_016872540 (OMIM: 604433,613119) PREDICTED: pota ( 103) 116 36.8 0.0095 >>NP_001257331 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 847 init1: 847 opt: 847 Z-score: 1182.4 bits: 224.4 E(85289): 4e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLG :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 70 80 90 100 110 120 pF1KB7 HLPETKPSP ::::::::: NP_001 HLPETKPSP >>NP_001257332 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 847 init1: 847 opt: 847 Z-score: 1182.4 bits: 224.4 E(85289): 4e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLG :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 70 80 90 100 110 120 pF1KB7 HLPETKPSP ::::::::: NP_001 HLPETKPSP >>NP_001257334 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 847 init1: 847 opt: 847 Z-score: 1182.4 bits: 224.4 E(85289): 4e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLG :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 70 80 90 100 110 120 pF1KB7 HLPETKPSP ::::::::: NP_001 HLPETKPSP >>NP_001121141 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 847 init1: 847 opt: 847 Z-score: 1182.4 bits: 224.4 E(85289): 4e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLG :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 70 80 90 100 110 120 pF1KB7 HLPETKPSP ::::::::: NP_001 HLPETKPSP >>NP_001257333 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 847 init1: 847 opt: 847 Z-score: 1182.4 bits: 224.4 E(85289): 4e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLG :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 70 80 90 100 110 120 pF1KB7 HLPETKPSP ::::::::: NP_001 HLPETKPSP >>NP_001121142 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 847 init1: 847 opt: 847 Z-score: 1182.4 bits: 224.4 E(85289): 4e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLG :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 70 80 90 100 110 120 pF1KB7 HLPETKPSP ::::::::: NP_001 HLPETKPSP >>NP_001121140 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 847 init1: 847 opt: 847 Z-score: 1182.4 bits: 224.4 E(85289): 4e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLG :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 70 80 90 100 110 120 pF1KB7 HLPETKPSP ::::::::: NP_001 HLPETKPSP >>NP_000210 (OMIM: 176261,612347,613695) potassium volta (129 aa) initn: 847 init1: 847 opt: 847 Z-score: 1182.4 bits: 224.4 E(85289): 4e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:1-129) 10 20 30 40 50 60 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLG :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_000 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 70 80 90 100 110 120 pF1KB7 HLPETKPSP ::::::::: NP_000 HLPETKPSP >>XP_016883831 (OMIM: 176261,612347,613695) PREDICTED: p (150 aa) initn: 847 init1: 847 opt: 847 Z-score: 1181.5 bits: 224.4 E(85289): 4.5e-59 Smith-Waterman score: 847; 99.2% identity (100.0% similar) in 129 aa overlap (1-129:22-150) 10 20 30 pF1KB7 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSGD :::::::::::::::::::::::::::::::::::::.: XP_016 MAYLEVCLGSLSCSSGTLMPRMILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSD 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 GKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARV 70 80 90 100 110 120 100 110 120 pF1KB7 LESYRSCYVVENHLAIEQPNTHLPETKPSP :::::::::::::::::::::::::::::: XP_016 LESYRSCYVVENHLAIEQPNTHLPETKPSP 130 140 150 >>NP_751951 (OMIM: 603796,611493,613693) potassium volta (123 aa) initn: 167 init1: 140 opt: 169 Z-score: 242.7 bits: 50.4 E(85289): 8.8e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (45-95:51-100) 20 30 40 50 60 70 pF1KB7 KLWQETVQQGGNMSGLARRSPRSGDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS ::.....:.:.:. ..:..: ..::. ::: NP_751 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS 30 40 50 60 70 80 80 90 100 110 120 pF1KB7 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP :::.. :: : :::: :. . NP_751 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP 90 100 110 120 129 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:29:38 2016 done: Fri Nov 4 04:29:39 2016 Total Scan time: 4.850 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]