FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7094, 186 aa 1>>>pF1KB7094 186 - 186 aa - 186 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1683+/-0.000762; mu= 13.1774+/- 0.046 mean_var=56.8868+/-11.315, 0's: 0 Z-trim(106.8): 18 B-trim: 4 in 1/49 Lambda= 0.170047 statistics sampled from 9214 (9223) to 9214 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.283), width: 16 Scan time: 1.970 The best scores are: opt bits E(32554) CCDS12132.1 TNFAIP8L1 gene_id:126282|Hs108|chr19 ( 186) 1202 302.8 8.2e-83 CCDS47257.1 TNFAIP8 gene_id:25816|Hs108|chr5 ( 188) 754 192.8 1e-49 CCDS47258.1 TNFAIP8 gene_id:25816|Hs108|chr5 ( 198) 754 192.9 1.1e-49 CCDS68933.1 TNFAIP8 gene_id:25816|Hs108|chr5 ( 210) 754 192.9 1.1e-49 CCDS81881.1 TNFAIP8L3 gene_id:388121|Hs108|chr15 ( 204) 694 178.1 2.9e-45 CCDS32241.1 TNFAIP8L3 gene_id:388121|Hs108|chr15 ( 292) 694 178.2 4e-45 CCDS985.1 TNFAIP8L2 gene_id:79626|Hs108|chr1 ( 184) 678 174.2 4e-44 >>CCDS12132.1 TNFAIP8L1 gene_id:126282|Hs108|chr19 (186 aa) initn: 1202 init1: 1202 opt: 1202 Z-score: 1600.2 bits: 302.8 E(32554): 8.2e-83 Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM 130 140 150 160 170 180 pF1KB7 LDEGSL :::::: CCDS12 LDEGSL >>CCDS47257.1 TNFAIP8 gene_id:25816|Hs108|chr5 (188 aa) initn: 754 init1: 754 opt: 754 Z-score: 1006.2 bits: 192.8 E(32554): 1e-49 Smith-Waterman score: 754; 57.7% identity (91.8% similar) in 182 aa overlap (2-183:4-185) 10 20 30 40 50 pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQK :.:..:.::.:::::.:.::.::.....:.:::::::::::::.:::.:...:::.: CCDS47 MATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 MLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAA ..:::.:...::..: :..:.. .::::...:..... ::::.:::::::.:::: ::. CCDS47 IIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 GLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLG : :::..::: . :::::::::.:.:: :..::.::::::.: .. ::...:.:.. CCDS47 LLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGIN 130 140 150 160 170 180 180 pF1KB7 RMLDEGSL .:::: CCDS47 KMLDEENI >>CCDS47258.1 TNFAIP8 gene_id:25816|Hs108|chr5 (198 aa) initn: 754 init1: 754 opt: 754 Z-score: 1005.8 bits: 192.9 E(32554): 1.1e-49 Smith-Waterman score: 754; 57.7% identity (91.8% similar) in 182 aa overlap (2-183:14-195) 10 20 30 40 pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATRE :.:..:.::.:::::.:.::.::.....:.:::::::::::::.::: CCDS47 MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTRE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 FTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVD .:...:::.:..:::.:...::..: :..:.. .::::...:..... ::::.::::::: CCDS47 YTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVD 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 FTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRS .:::: ::. : :::..::: . :::::::::.:.:: :..::.::::::.: .. CCDS47 YTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKP 130 140 150 160 170 180 170 180 pF1KB7 HLRRICEGLGRMLDEGSL ::...:.:...:::: CCDS47 HLQKLCDGINKMLDEENI 190 >>CCDS68933.1 TNFAIP8 gene_id:25816|Hs108|chr5 (210 aa) initn: 754 init1: 754 opt: 754 Z-score: 1005.4 bits: 192.9 E(32554): 1.1e-49 Smith-Waterman score: 754; 57.7% identity (91.8% similar) in 182 aa overlap (2-183:26-207) 10 20 30 pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSS :.:..:.::.:::::.:.::.::.....:.::::: CCDS68 MTLPRYCEVVLLIAHGEKMLKLVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 EVLDELYRATREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARC ::::::::.:::.:...:::.:..:::.:...::..: :..:.. .::::...:..... CCDS68 EVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQ 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 LAMTAVSFHQVDFTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFL ::::.:::::::.:::: ::. : :::..::: . :::::::::.:.:: :..::.:: CCDS68 LAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFL 130 140 150 160 170 180 160 170 180 pF1KB7 AALYGPAEPYRSHLRRICEGLGRMLDEGSL ::::.: .. ::...:.:...:::: CCDS68 AALYNPFGNFKPHLQKLCDGINKMLDEENI 190 200 210 >>CCDS81881.1 TNFAIP8L3 gene_id:388121|Hs108|chr15 (204 aa) initn: 686 init1: 686 opt: 694 Z-score: 926.1 bits: 178.1 E(32554): 2.9e-45 Smith-Waterman score: 694; 55.1% identity (85.9% similar) in 185 aa overlap (2-186:20-204) 10 20 30 40 pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDEL :.::.::::::::::.:::.:::.:. .:.::::::..::: CCDS81 MDSDSGEQSEGEPVTAAGPDVFSSKSLALQAQKKILSKIASKTVANMLIDDTSSEIFDEL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 YRATREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAV :..:.: :...:::.:..:.:.:::.:.:.: :..:.. :::.....::.. ::: : CCDS81 YKVTKEHTHNKKEAHKIMKDLIKVAIKIGILYRNNQFSQEELVIVEKFRKKLNQTAMTIV 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 SFHQVDFTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGP ::..:..:::: ::. : ::.::.:. : ::: ..::::::::.:.:: .::..::. CCDS81 SFYEVEYTFDRNVLSNLLHECKDLVHELVQRHLTPRTHGRINHVFNHFADVEFLSTLYSL 130 140 150 160 170 180 170 180 pF1KB7 AEPYRSHLRRICEGLGRMLDEGSL : .:.:::::....::: : CCDS81 DGDCRPNLKRICEGINKLLDEKVL 190 200 >>CCDS32241.1 TNFAIP8L3 gene_id:388121|Hs108|chr15 (292 aa) initn: 686 init1: 686 opt: 694 Z-score: 923.6 bits: 178.2 E(32554): 4e-45 Smith-Waterman score: 694; 55.1% identity (85.9% similar) in 185 aa overlap (2-186:108-292) 10 20 30 pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLV :.::.::::::::::.:::.:::.:. .:. CCDS32 VAVDAQPAARSMDSDSGEQSEGEPVTAAGPDVFSSKSLALQAQKKILSKIASKTVANMLI 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB7 DDTSSEVLDELYRATREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFR ::::::..::::..:.: :...:::.:..:.:.:::.:.:.: :..:.. :::.....:: CCDS32 DDTSSEIFDELYKVTKEHTHNKKEAHKIMKDLIKVAIKIGILYRNNQFSQEELVIVEKFR 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB7 HRARCLAMTAVSFHQVDFTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLA .. ::: :::..:..:::: ::. : ::.::.:. : ::: ..::::::::.:.: CCDS32 KKLNQTAMTIVSFYEVEYTFDRNVLSNLLHECKDLVHELVQRHLTPRTHGRINHVFNHFA 200 210 220 230 240 250 160 170 180 pF1KB7 DCDFLAALYGPAEPYRSHLRRICEGLGRMLDEGSL : .::..::. : .:.:::::....::: : CCDS32 DVEFLSTLYSLDGDCRPNLKRICEGINKLLDEKVL 260 270 280 290 >>CCDS985.1 TNFAIP8L2 gene_id:79626|Hs108|chr1 (184 aa) initn: 676 init1: 607 opt: 678 Z-score: 905.6 bits: 174.2 E(32554): 4e-44 Smith-Waterman score: 678; 57.0% identity (83.3% similar) in 186 aa overlap (1-186:1-184) 10 20 30 40 50 60 pF1KB7 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML :..::.:::::::.::::::::...:. ...:.:::::::::::...:.:.:: .::... CCDS98 MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGL :.:.:::.:...: :. ..: :::: :::.. : ::::.:: .:::::. :::. : CCDS98 KDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM ::::.: . : ::: :::::: ::: :..: .:.::::: . .:: .::.:: .. CCDS98 TECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGP--DFTQHLGKICDGLRKL 130 140 150 160 170 pF1KB7 LDEGSL ::::.: CCDS98 LDEGKL 180 186 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:39:28 2016 done: Fri Nov 4 04:39:28 2016 Total Scan time: 1.970 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]