FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7095, 188 aa 1>>>pF1KB7095 188 - 188 aa - 188 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8319+/-0.000947; mu= 9.6231+/- 0.056 mean_var=70.5386+/-14.265, 0's: 0 Z-trim(104.8): 53 B-trim: 87 in 1/50 Lambda= 0.152708 statistics sampled from 8034 (8087) to 8034 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.248), width: 16 Scan time: 1.820 The best scores are: opt bits E(32554) CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 1258 286.3 7.8e-78 CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX ( 190) 902 207.8 3.2e-54 CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 664 155.4 2e-38 CCDS77667.1 DUSP18 gene_id:150290|Hs108|chr22 ( 117) 342 84.4 2.9e-17 CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 ( 367) 338 83.7 1.5e-16 CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 315 78.6 4.1e-15 CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 ( 394) 315 78.6 5.2e-15 CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 ( 176) 309 77.2 6.3e-15 CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 310 77.4 7e-15 CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 294 73.9 8e-14 CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 295 74.2 1.1e-13 CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 ( 295) 289 72.8 2.1e-13 CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 ( 625) 293 73.8 2.3e-13 CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 ( 217) 278 70.4 8.7e-13 CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 ( 184) 275 69.7 1.2e-12 CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 ( 205) 275 69.7 1.3e-12 CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 277 70.3 2.7e-12 CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 ( 211) 263 67.1 8.4e-12 CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 ( 314) 264 67.3 1e-11 CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 ( 482) 260 66.5 2.8e-11 CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 ( 188) 251 64.4 4.7e-11 CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 ( 659) 255 65.5 7.8e-11 >>CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 (188 aa) initn: 1258 init1: 1258 opt: 1258 Z-score: 1510.9 bits: 286.3 E(32554): 7.8e-78 Smith-Waterman score: 1258; 100.0% identity (100.0% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK 130 140 150 160 170 180 pF1KB7 EVRLMIPL :::::::: CCDS13 EVRLMIPL >>CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX (190 aa) initn: 918 init1: 894 opt: 902 Z-score: 1086.9 bits: 207.8 E(32554): 3.2e-54 Smith-Waterman score: 902; 68.9% identity (91.1% similar) in 190 aa overlap (1-188:1-190) 10 20 30 40 50 pF1KB7 MTAPSCAFPVQ--FRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVN ::: . .: . .:::. ..::::.::..:::::::.::.::::.:: ..:.:::::: CCDS14 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 TLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY ...: :::..:::.:. .::: :::::::: ::...:.:::::::: :::::::.::::: CCDS14 VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 LMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIY :::::.:::::::::::: :::::::.:::::::.:::.::..:::.:..:::: ::::: CCDS14 LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY 130 140 150 160 170 180 180 pF1KB7 EKEVRLMIPL ::..:.:: . CCDS14 EKDLRMMISM 190 >>CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 (198 aa) initn: 661 init1: 643 opt: 664 Z-score: 803.3 bits: 155.4 E(32554): 2e-38 Smith-Waterman score: 664; 50.3% identity (83.2% similar) in 179 aa overlap (9-187:16-194) 10 20 30 40 50 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVS : .. . ...:..:::.::... : .:.:. .:.. :: ..:.. CCDS11 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 VEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAA .:. : . ...:..::.:: :.. . .:: .::.:::: :.: ::.::::::::::. CCDS11 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 LCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGM ::.:::::.: . ::.:..:.:. ::.:::: :::.::: :: :::::.::.::..: :. CCDS11 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI 130 140 150 160 170 180 180 pF1KB7 IPDIYEKEVRLMIPL .::.:::: : ..: CCDS11 VPDVYEKESRHLMPYWGI 190 >>CCDS77667.1 DUSP18 gene_id:150290|Hs108|chr22 (117 aa) initn: 356 init1: 342 opt: 342 Z-score: 423.5 bits: 84.4 E(32554): 2.9e-17 Smith-Waterman score: 342; 100.0% identity (100.0% similar) in 55 aa overlap (1-55:1-55) 10 20 30 40 50 60 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVERGDEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM CCDS77 GPYFAALCCWCEPLSCPVPRLPHEVPRHVPAGRPHVDQVMPAHHPTQQRLLGAAHPL 70 80 90 100 110 >>CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 (367 aa) initn: 352 init1: 325 opt: 338 Z-score: 410.8 bits: 83.7 E(32554): 1.5e-16 Smith-Waterman score: 338; 34.9% identity (65.7% similar) in 172 aa overlap (5-176:163-330) 10 20 30 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVA ::. :. . : .: .: ::.... CCDS43 PELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPL-YDQ---GGPVEILPFLYLGSAYH 140 150 160 170 180 40 50 60 70 80 90 pF1KB7 ANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVE :. : ::.. :: .::::.. : . :: ..:: :. .. . ..:. : : :.. CCDS43 ASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIK 190 200 210 220 230 240 100 110 120 130 140 150 pF1KB7 MKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHY ::...:: ::.::::..::::::. . ..: .: ..:. : :: :: .: ::... CCDS43 NAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQF 250 260 270 280 290 300 160 170 180 pF1KB7 EFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIPL : :... . ..::. . : CCDS43 ESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC 310 320 330 340 350 360 >>CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 (303 aa) initn: 304 init1: 304 opt: 315 Z-score: 384.8 bits: 78.6 E(32554): 4.1e-15 Smith-Waterman score: 315; 33.9% identity (64.3% similar) in 168 aa overlap (5-172:94-257) 10 20 30 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVA ::. :.. . .: .: ::.... CCDS60 PEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLH----DQGGPVEILPFLYLGSAYH 70 80 90 100 110 40 50 60 70 80 90 pF1KB7 ANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVE : . ::.. :: ..::: . : . :: .:: :. .. . ..: ..: .:. CCDS60 AARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVK 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB7 MKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHY .::.:.:: ::.::::..:::::: . . : .: ..:. : :: :: .: ::... CCDS60 DCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQF 180 190 200 210 220 230 160 170 180 pF1KB7 EFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIPL : :... . . ..:: : CCDS60 ESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITT 240 250 260 270 280 290 >>CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 (394 aa) initn: 332 init1: 304 opt: 315 Z-score: 383.0 bits: 78.6 E(32554): 5.2e-15 Smith-Waterman score: 315; 33.9% identity (64.3% similar) in 168 aa overlap (5-172:185-348) 10 20 30 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVA ::. :.. . .: .: ::.... CCDS60 PEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLH----DQGGPVEILPFLYLGSAYH 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB7 ANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVE : . ::.. :: ..::: . : . :: .:: :. .. . ..: ..: .:. CCDS60 AARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVK 220 230 240 250 260 270 100 110 120 130 140 150 pF1KB7 MKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHY .::.:.:: ::.::::..:::::: . . : .: ..:. : :: :: .: ::... CCDS60 DCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQF 280 290 300 310 320 330 160 170 180 pF1KB7 EFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIPL : :... . . ..:: : CCDS60 ESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITT 340 350 360 370 380 390 >>CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 (176 aa) initn: 289 init1: 289 opt: 309 Z-score: 381.4 bits: 77.2 E(32554): 6.3e-15 Smith-Waterman score: 309; 31.5% identity (60.5% similar) in 162 aa overlap (15-176:14-175) 10 20 30 40 50 60 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL : : ... ::..... ::. . .:. .:. .::: . . CCDS33 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPR 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM . ..::: :.: : ..: .... : :..: : :::::.: :::: CCDS33 APGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLM 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK .....:: : .:: ::. .:: ::: :: .:: : ... .. .:. :. CCDS33 RHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA 120 130 140 150 160 170 pF1KB7 EVRLMIPL >>CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 (235 aa) initn: 234 init1: 234 opt: 310 Z-score: 380.6 bits: 77.4 E(32554): 7e-15 Smith-Waterman score: 310; 31.0% identity (62.6% similar) in 171 aa overlap (18-188:3-171) 10 20 30 40 50 60 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL .:.... .::..: . :.. .:. :.:: .:.. : . : CCDS13 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIH-ESPQPL 10 20 30 40 70 80 90 100 110 120 pF1KB7 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM .:: :...::::.:. . : . :: ... : :.:: ::.:::... ::.: CCDS13 LQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVM 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK ... :. :. ::: :: :: .:: .. . ... ... : : :. CCDS13 TVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWAS-SQKLRRQLEERFGESPFRDEE 110 120 130 140 150 160 pF1KB7 EVRLMIPL :.: ..:: CCDS13 ELRALLPLCKRCRQGSATSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFS 170 180 190 200 210 220 >>CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 (232 aa) initn: 234 init1: 234 opt: 294 Z-score: 361.6 bits: 73.9 E(32554): 8e-14 Smith-Waterman score: 294; 31.3% identity (61.4% similar) in 166 aa overlap (23-188:5-168) 10 20 30 40 50 60 pF1KB7 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL . .::..: . :.. .:. :.:: .:.. : . : CCDS82 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIH-ESPQPL 10 20 30 40 70 80 90 100 110 120 pF1KB7 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM .:: :...::::.:. . : . :: ... : :.:: ::.:::... ::.: CCDS82 LQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVM 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK ... :. :. ::: :: :: .:: .. . ... ... : : :. CCDS82 TVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWAS-SQKLRRQLEERFGESPFRDEE 110 120 130 140 150 160 pF1KB7 EVRLMIPL :.: ..:: CCDS82 ELRALLPLCKRCRQGSATSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFS 170 180 190 200 210 220 188 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:40:01 2016 done: Fri Nov 4 04:40:01 2016 Total Scan time: 1.820 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]