FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7098, 198 aa 1>>>pF1KB7098 198 - 198 aa - 198 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4830+/-0.000946; mu= 11.5677+/- 0.056 mean_var=66.7687+/-12.916, 0's: 0 Z-trim(105.2): 74 B-trim: 68 in 1/49 Lambda= 0.156960 statistics sampled from 8199 (8278) to 8199 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.254), width: 16 Scan time: 1.880 The best scores are: opt bits E(32554) CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 1350 314.6 2.6e-86 CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 664 159.2 1.4e-39 CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX ( 190) 613 147.7 4.3e-36 CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 ( 367) 379 94.8 6.7e-20 CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 367 92.1 3.8e-19 CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 ( 394) 367 92.1 4.7e-19 CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 ( 314) 354 89.1 3e-18 CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 342 86.6 3.7e-17 CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 ( 176) 321 81.5 3.2e-16 CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 320 81.5 7.4e-16 CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 ( 211) 307 78.4 3.4e-15 CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 ( 482) 304 77.9 1.1e-14 CCDS55882.1 SSH1 gene_id:54434|Hs108|chr12 ( 692) 302 77.5 2.1e-14 CCDS53825.1 SSH1 gene_id:54434|Hs108|chr12 ( 703) 302 77.5 2.1e-14 CCDS11253.1 SSH2 gene_id:85464|Hs108|chr17 (1423) 304 78.1 2.8e-14 CCDS74024.1 SSH2 gene_id:85464|Hs108|chr17 (1450) 304 78.1 2.8e-14 CCDS9121.1 SSH1 gene_id:54434|Hs108|chr12 (1049) 302 77.6 2.9e-14 CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 ( 188) 290 74.5 4.4e-14 CCDS33766.2 DUSP7 gene_id:1849|Hs108|chr3 ( 419) 294 75.6 4.7e-14 CCDS9033.1 DUSP6 gene_id:1848|Hs108|chr12 ( 381) 293 75.4 5.1e-14 CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX ( 384) 288 74.2 1.1e-13 CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 ( 625) 284 73.4 3.2e-13 CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 271 70.3 1.1e-12 CCDS9711.1 STYX gene_id:6815|Hs108|chr14 ( 223) 266 69.1 2.2e-12 CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 ( 217) 265 68.9 2.5e-12 CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 ( 198) 260 67.8 5.1e-12 CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 ( 248) 260 67.8 6.2e-12 CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 259 67.6 6.9e-12 CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 ( 184) 253 66.2 1.4e-11 CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 ( 205) 247 64.8 4.1e-11 CCDS30932.1 DUSP27 gene_id:92235|Hs108|chr1 (1158) 254 66.8 6e-11 >>CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 (198 aa) initn: 1350 init1: 1350 opt: 1350 Z-score: 1663.2 bits: 314.6 E(32554): 2.6e-86 Smith-Waterman score: 1350; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198) 10 20 30 40 50 60 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI 130 140 150 160 170 180 190 pF1KB7 VPDVYEKESRHLMPYWGI :::::::::::::::::: CCDS11 VPDVYEKESRHLMPYWGI 190 >>CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 (188 aa) initn: 661 init1: 643 opt: 664 Z-score: 824.0 bits: 159.2 E(32554): 1.4e-39 Smith-Waterman score: 664; 50.3% identity (83.2% similar) in 179 aa overlap (16-194:9-187) 10 20 30 40 50 60 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT : .. . ...:..:::.::... : .:.:. .:.. :: ..:.. CCDS13 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVS 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT .:. : . ...:..::.:: :.. . .:: .::.:::: :.: ::.::::::::::. CCDS13 VEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI ::.:::::.: . ::.:..:.:. ::.:::: :::.::: :: :::::.::.::..: :. CCDS13 LCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGM 120 130 140 150 160 170 190 pF1KB7 VPDVYEKESRHLMPYWGI .::.:::: : ..: CCDS13 IPDIYEKEVRLMIPL 180 >>CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX (190 aa) initn: 627 init1: 606 opt: 613 Z-score: 761.5 bits: 147.7 E(32554): 4.3e-36 Smith-Waterman score: 613; 48.0% identity (81.7% similar) in 175 aa overlap (19-193:14-188) 10 20 30 40 50 60 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT ... .: ...::: ::::. : .:... ::.. :: ::::. CCDS14 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNAS 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT .:. : . ..:.:::..: . . .:: .:: ::... ..: ::.:: :::::::. CCDS14 VEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSAS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI ::.:::::.:.. ::.:..:.:.:::.:::: :::.:::.:: .::...::.:...: : CCDS14 LCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGN 120 130 140 150 160 170 190 pF1KB7 VPDVYEKESRHLMPYWGI .::.:::. : .. CCDS14 IPDIYEKDLRMMISM 180 190 >>CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 (367 aa) initn: 369 init1: 369 opt: 379 Z-score: 470.7 bits: 94.8 E(32554): 6.7e-20 Smith-Waterman score: 379; 37.9% identity (65.8% similar) in 161 aa overlap (23-183:170-330) 10 20 30 40 50 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARG : :: ..: :.:: . :: . .:.: : CCDS43 STPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALG 140 150 160 170 180 190 60 70 80 90 100 110 pF1KB7 ITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCA :: ..:.. . :: ...: ..:. : .: :. .:. . : : :.. : ..::: CCDS43 ITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQ 200 210 220 230 240 250 120 130 140 150 160 170 pF1KB7 AGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVK ::.:::::.:.::::. . : : ::...:: :: .: :: .: ::...: :... CCDS43 AGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSA 260 270 280 290 300 310 180 190 pF1KB7 MVQTPYGIVPDVYEKESRHLMPYWGI . .: : : CCDS43 EAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC 320 330 340 350 360 >>CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 (303 aa) initn: 349 init1: 349 opt: 367 Z-score: 457.3 bits: 92.1 E(32554): 3.8e-19 Smith-Waterman score: 367; 38.9% identity (66.9% similar) in 157 aa overlap (23-179:101-257) 10 20 30 40 50 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARG : :: ..: :.:: . :. : .:.: : CCDS60 KALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALG 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB7 ITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCA :: ..:.. . :: ...: .:. : .: :. .: . . : .:. .: .:::: CCDS60 ITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQ 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB7 AGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVK ::.:::::.:.:::: . : : ::...:: :: .: :: .: ::...: :... : . CCDS60 AGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAA 200 210 220 230 240 250 180 190 pF1KB7 MVQTPYGIVPDVYEKESRHLMPYWGI . .: : CCDS60 EAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC 260 270 280 290 300 >>CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 (394 aa) initn: 349 init1: 349 opt: 367 Z-score: 455.6 bits: 92.1 E(32554): 4.7e-19 Smith-Waterman score: 367; 38.9% identity (66.9% similar) in 157 aa overlap (23-179:192-348) 10 20 30 40 50 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARG : :: ..: :.:: . :. : .:.: : CCDS60 KALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALG 170 180 190 200 210 220 60 70 80 90 100 110 pF1KB7 ITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCA :: ..:.. . :: ...: .:. : .: :. .: . . : .:. .: .:::: CCDS60 ITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQ 230 240 250 260 270 280 120 130 140 150 160 170 pF1KB7 AGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVK ::.:::::.:.:::: . : : ::...:: :: .: :: .: ::...: :... : . CCDS60 AGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAA 290 300 310 320 330 340 180 190 pF1KB7 MVQTPYGIVPDVYEKESRHLMPYWGI . .: : CCDS60 EAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC 350 360 370 380 390 >>CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 (314 aa) initn: 368 init1: 349 opt: 354 Z-score: 441.2 bits: 89.1 E(32554): 3e-18 Smith-Waterman score: 354; 42.4% identity (66.7% similar) in 144 aa overlap (23-166:169-312) 10 20 30 40 50 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARG : :: ..: :::: : .:. . ::: : CCDS20 CPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACG 140 150 160 170 180 190 60 70 80 90 100 110 pF1KB7 ITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCA :: ..:.. :: :.: ..:. : . :. .:. . : :. . : .:::: CCDS20 ITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQ 200 210 220 230 240 250 120 130 140 150 160 170 pF1KB7 AGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVK ::.:::::.:.::::. . : : ::...:: :: :: :: .: ::...: :.. CCDS20 AGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH 260 270 280 290 300 310 180 190 pF1KB7 MVQTPYGIVPDVYEKESRHLMPYWGI >>CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 (665 aa) initn: 291 init1: 255 opt: 342 Z-score: 421.4 bits: 86.6 E(32554): 3.7e-17 Smith-Waterman score: 349; 35.0% identity (63.0% similar) in 200 aa overlap (5-194:138-336) 10 20 30 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSL :.::: : .. . ..:: ..: .: CCDS86 LGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGP-TRILPNL 110 120 130 140 150 160 40 50 60 70 80 90 pF1KB7 FLGRGSVASNRHLLQARGITCIVNATIEIPNFNW-PQFEYVKVPLADMPHAPIGLYFDTV .:: . :..:.: :: ..::. :. .. :. ....::. : : ..: CCDS86 YLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKS 170 180 190 200 210 220 100 110 120 130 140 150 pF1KB7 ADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVG .: :.... ..: .:::: ::.:::::. :::.:: .. : ::: .:: .::.: :: . CCDS86 VDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFN 230 240 250 260 270 280 160 170 180 190 pF1KB7 FWRQLIDYERQLFG-------KSTVKMV--QTPYGIVPDVYEKESRHLMPYWGI : ::.:::... . :: .:.. . : :: : : .. : CCDS86 FLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSAT 290 300 310 320 330 340 CCDS86 SEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKS 350 360 370 380 390 400 >>CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 (176 aa) initn: 328 init1: 307 opt: 321 Z-score: 404.7 bits: 81.5 E(32554): 3.2e-16 Smith-Waterman score: 321; 33.8% identity (63.1% similar) in 157 aa overlap (27-183:19-175) 10 20 30 40 50 60 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT ..... ::::: . .:. .. : :.: ::.. CCDS33 MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVS 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT . :. : ..::. : : . ... . .... : :: ::.: : ::::. CCDS33 RQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI .: ::::. ... : .:.. ::. ::: .:: ::: :: ::. : ..: .. :. CCDS33 VCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGL 120 130 140 150 160 170 190 pF1KB7 VPDVYEKESRHLMPYWGI :. CCDS33 GPEA >>CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 (384 aa) initn: 333 init1: 315 opt: 320 Z-score: 398.2 bits: 81.5 E(32554): 7.4e-16 Smith-Waterman score: 320; 37.5% identity (65.3% similar) in 144 aa overlap (23-166:175-318) 10 20 30 40 50 pF1KB7 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARG : :: ..: :.:: . ::. ..: CCDS75 PISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLH 150 160 170 180 190 200 60 70 80 90 100 110 pF1KB7 ITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCA :: ..:.. . . ...: .:. : : :. .:. . : : : .: : .:::: CCDS75 ITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCE 210 220 230 240 250 260 120 130 140 150 160 170 pF1KB7 AGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVK ::.::: :.:.::::: .. : ::....: :: .. :: :: ::..:: ... CCDS75 AGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNP 270 280 290 300 310 320 180 190 pF1KB7 MVQTPYGIVPDVYEKESRHLMPYWGI CCDS75 QPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC 330 340 350 360 370 380 198 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:41:40 2016 done: Fri Nov 4 04:41:40 2016 Total Scan time: 1.880 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]