FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7110, 260 aa 1>>>pF1KB7110 260 - 260 aa - 260 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7256+/-0.000956; mu= 12.7589+/- 0.058 mean_var=73.2185+/-14.916, 0's: 0 Z-trim(105.6): 53 B-trim: 0 in 0/52 Lambda= 0.149887 statistics sampled from 8445 (8498) to 8445 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.261), width: 16 Scan time: 2.300 The best scores are: opt bits E(32554) CCDS31645.1 KCTD21 gene_id:283219|Hs108|chr11 ( 260) 1701 377.0 7.2e-105 CCDS32545.1 KCTD11 gene_id:147040|Hs108|chr17 ( 232) 529 123.5 1.3e-28 CCDS2891.1 KCTD6 gene_id:200845|Hs108|chr3 ( 237) 485 114.0 9.5e-26 CCDS12434.1 KCTD15 gene_id:79047|Hs108|chr19 ( 234) 350 84.8 5.7e-17 CCDS46039.1 KCTD15 gene_id:79047|Hs108|chr19 ( 283) 350 84.9 6.8e-17 CCDS11888.1 KCTD1 gene_id:284252|Hs108|chr18 ( 257) 338 82.3 3.8e-16 CCDS9396.1 KCTD4 gene_id:386618|Hs108|chr13 ( 259) 312 76.6 1.9e-14 CCDS34260.1 KCTD16 gene_id:57528|Hs108|chr5 ( 428) 298 73.7 2.3e-13 CCDS9455.1 KCTD12 gene_id:115207|Hs108|chr13 ( 325) 284 70.6 1.5e-12 CCDS12560.1 SHKBP1 gene_id:92799|Hs108|chr19 ( 707) 278 69.5 7.2e-12 CCDS2330.1 KCTD18 gene_id:130535|Hs108|chr2 ( 426) 275 68.7 7.3e-12 CCDS41889.1 KCNRG gene_id:283518|Hs108|chr13 ( 229) 267 66.9 1.4e-11 CCDS10661.1 KCTD13 gene_id:253980|Hs108|chr16 ( 329) 269 67.4 1.4e-11 CCDS9424.1 KCNRG gene_id:283518|Hs108|chr13 ( 272) 267 66.9 1.7e-11 CCDS9128.1 KCTD10 gene_id:83892|Hs108|chr12 ( 313) 266 66.7 2.2e-11 CCDS55117.1 KCTD7 gene_id:154881|Hs108|chr7 ( 288) 261 65.6 4.3e-11 CCDS5534.1 KCTD7 gene_id:154881|Hs108|chr7 ( 289) 261 65.6 4.3e-11 CCDS60908.1 KCTD14 gene_id:65987|Hs108|chr11 ( 225) 254 64.1 9.9e-11 >>CCDS31645.1 KCTD21 gene_id:283219|Hs108|chr11 (260 aa) initn: 1701 init1: 1701 opt: 1701 Z-score: 1996.2 bits: 377.0 E(32554): 7.2e-105 Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260) 10 20 30 40 50 60 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLNQRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLNQRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 QTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNLSSITSHLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 QTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNLSSITSHLQD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 PNHLTLDWVANVEGLPEEEYTKQNLKRLWVVPANKQINSFQVFVEEVLKIALSDGFCIDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PNHLTLDWVANVEGLPEEEYTKQNLKRLWVVPANKQINSFQVFVEEVLKIALSDGFCIDS 190 200 210 220 230 240 250 260 pF1KB7 SHPHALDFMNNKIIRLIRYR :::::::::::::::::::: CCDS31 SHPHALDFMNNKIIRLIRYR 250 260 >>CCDS32545.1 KCTD11 gene_id:147040|Hs108|chr17 (232 aa) initn: 457 init1: 246 opt: 529 Z-score: 627.3 bits: 123.5 E(32554): 1.3e-28 Smith-Waterman score: 529; 39.7% identity (68.2% similar) in 239 aa overlap (28-259:1-232) 10 20 30 40 50 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSG--KMPTKRDSQG--NCFIDRDGKVF :::::: . :: . .::: . :::::::.: CCDS32 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAF 10 20 30 60 70 80 90 100 110 pF1KB7 RYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEV-ELSKAEKNAMLNIT :.:::::: ..::::. . : .::: ::::::..::..::.: :. . . : :.:. CCDS32 RHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQGTPAPTAALLHAD 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB7 LNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNLSSIT .. . :::..:..:. : ::: ....: ::.: :. : : .. : ..:. . . CCDS32 VDVSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDSECLGALRAR-FGVASGDRAEGS 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 SHLQDPNHLTLDWVANVEGLPEEEYTKQNLKRLWVV-PANK-QINSFQVFVEEVLKIALS :.. :.:. ::: :: . .:. ::. :... .. . :.::::..:: CCDS32 PHFH------LEWAPRPVELPEVEYGRLGLQPLWTGGPGERREVVGTPSFLEEVLRVALE 160 170 180 190 200 240 250 260 pF1KB7 DGFCIDSSHPHALDFMNNKIIRLIRYR :: .:: : :..:.. .:..:. CCDS32 HGFRLDSVFPDPEDLLNSRSLRFVRH 210 220 230 >>CCDS2891.1 KCTD6 gene_id:200845|Hs108|chr3 (237 aa) initn: 476 init1: 476 opt: 485 Z-score: 575.8 bits: 114.0 E(32554): 9.5e-26 Smith-Waterman score: 485; 71.4% identity (89.8% similar) in 98 aa overlap (1-98:10-107) 10 20 30 40 50 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDR :.::.::::::.::::::.::: .:::::::::.: .:: :: ::: :::: CCDS28 MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAM :: .:::.:::::::.: :: ::.:. :::.::::::..:::. :.. CCDS28 DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 LNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNL CCDS28 VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG 130 140 150 160 170 180 >>CCDS12434.1 KCTD15 gene_id:79047|Hs108|chr19 (234 aa) initn: 372 init1: 221 opt: 350 Z-score: 418.1 bits: 84.8 E(32554): 5.7e-17 Smith-Waterman score: 350; 46.7% identity (81.3% similar) in 107 aa overlap (4-109:57-163) 10 20 30 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMF :. ..:::..::.::::::..::: .. .: CCDS12 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 SGKMPTKRDS-QGNCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPL .: : :: . . ::::::..:::.:.:::::.: ::.::....:: .:: .::.::. CCDS12 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB7 IEALQEKEVELSKAEKNAMLNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTS .. :.. . : . ... CCDS12 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN 150 160 170 180 190 200 >>CCDS46039.1 KCTD15 gene_id:79047|Hs108|chr19 (283 aa) initn: 372 init1: 221 opt: 350 Z-score: 416.8 bits: 84.9 E(32554): 6.8e-17 Smith-Waterman score: 350; 46.7% identity (81.3% similar) in 107 aa overlap (4-109:57-163) 10 20 30 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMF :. ..:::..::.::::::..::: .. .: CCDS46 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 SGKMPTKRDS-QGNCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPL .: : :: . . ::::::..:::.:.:::::.: ::.::....:: .:: .::.::. CCDS46 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB7 IEALQEKEVELSKAEKNAMLNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTS .. :.. . : . ... CCDS46 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN 150 160 170 180 190 200 >>CCDS11888.1 KCTD1 gene_id:284252|Hs108|chr18 (257 aa) initn: 338 init1: 208 opt: 338 Z-score: 403.4 bits: 82.3 E(32554): 3.8e-16 Smith-Waterman score: 338; 50.5% identity (82.1% similar) in 95 aa overlap (4-97:31-125) 10 20 30 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMF :. ..:::..::.::::::..:.: .: .: CCDS11 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 SGKMPTKRDS-QGNCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPL .: : :: . . ::::::..:::::::::::.: .:.::... :: .:: ..:.::. CCDS11 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 IEALQEKEVELSKAEKNAMLNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTS . .. CCDS11 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 130 140 150 160 170 180 >>CCDS9396.1 KCTD4 gene_id:386618|Hs108|chr13 (259 aa) initn: 343 init1: 299 opt: 312 Z-score: 373.0 bits: 76.6 E(32554): 1.9e-14 Smith-Waterman score: 312; 42.9% identity (73.7% similar) in 133 aa overlap (5-135:35-166) 10 20 30 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFS .:::::: :: :. :::..::..: .. . CCDS93 INRREKEKEYEGKHNSLEDTDQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVN 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 GKMPTKRDSQGNCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIE ::. :..:. :::::: .::..:::::...: ::: :.: :: .::.:.:.. : : CCDS93 GKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 ALQEK-EVELSKAEKNAMLNITLNQ-RVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTS .. . : : .....:.:: :. : : ... .::.. : CCDS93 EVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFC-NAPDFISKIKSRIVLVSKSRLDGF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 CLFLKLLGSKLFYCSNGNLSSITSHLQDPNHLTLDWVANVEGLPEEEYTKQNLKRLWVVP CCDS93 PEEFSISSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLD 190 200 210 220 230 240 >>CCDS34260.1 KCTD16 gene_id:57528|Hs108|chr5 (428 aa) initn: 303 init1: 209 opt: 298 Z-score: 353.3 bits: 73.7 E(32554): 2.3e-13 Smith-Waterman score: 298; 45.8% identity (67.3% similar) in 107 aa overlap (5-107:27-133) 10 20 30 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMP . :::::..: : .:: :.: :.: ::: : CCDS34 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 TK----RDSQGNCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIE : .::.: :::::: .:::::..:: .. ::. : : : :.:::...:. :.. CCDS34 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 ALQEKEVELSKAEKNAMLNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCL : :.. : : CCDS34 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 >>CCDS9455.1 KCTD12 gene_id:115207|Hs108|chr13 (325 aa) initn: 300 init1: 183 opt: 284 Z-score: 338.8 bits: 70.6 E(32554): 1.5e-12 Smith-Waterman score: 284; 45.8% identity (74.0% similar) in 96 aa overlap (3-96:34-129) 10 20 30 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAM : . :::::..:.: :..: :::.: : CCDS94 ADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRM 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 FSGKMPTK--RDSQGNCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQ :. ..: . :::.: :.:::: .:::::..:: .: ::. : : . :.:::..... CCDS94 FTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 PLIEALQEKEVELSKAEKNAMLNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFS :.. : CCDS94 ELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLELAS 130 140 150 160 170 180 >>CCDS12560.1 SHKBP1 gene_id:92799|Hs108|chr19 (707 aa) initn: 290 init1: 220 opt: 278 Z-score: 326.5 bits: 69.5 E(32554): 7.2e-12 Smith-Waterman score: 278; 35.9% identity (61.5% similar) in 195 aa overlap (5-190:21-207) 10 20 30 40 pF1KB7 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQ : :::::: ..:: ::: .:::......::.. : .: CCDS12 MAAAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDET 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 GNCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELS : ::::: :: :::::::..:: :. . .::. ::.:: . ::.. :: .: ::. CCDS12 GAIFIDRDPTVFAPILNFLRTKELD-PRGVHGSSLLH-EAQFYGLTPLVRRLQLRE-ELD 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 KAE-KNAMLNITLNQRVQTVHFTVREA---PQIYSLSSSSMEVFNANIFSTSCLFLKLLG .. :...: : : :. :.. :: .:.. : .: . . ::: CCDS12 RSSCGNVLFNGYLPPPVFPVKRRNRHSLVGPQ--QLGGRPAPVRRSNTMPPNLGNAGLLG 120 130 140 150 160 170 170 180 190 200 210 pF1KB7 SKLFYCSNGNLSSITSHLQDPNHLTL-----DWVANVEGLPEEEYTKQNLKRLWVVPANK : .. . : ... ..:. . : .:.: CCDS12 RML---DEKTPPSPSGQPEEPGMVRLVCGHHNWIAVAYTQFLVCYRLKEASGWQLVFSSP 180 190 200 210 220 230 220 230 240 250 260 pF1KB7 QINSFQVFVEEVLKIALSDGFCIDSSHPHALDFMNNKIIRLIRYR CCDS12 RLDWPIERLALTARVHGGALGEHDKMVAAATGSEILLWALQAEGGGSEIGVFHLGVPVEA 240 250 260 270 280 290 260 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:45:35 2016 done: Fri Nov 4 04:45:35 2016 Total Scan time: 2.300 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]