FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7115, 279 aa 1>>>pF1KB7115 279 - 279 aa - 279 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3448+/-0.000299; mu= 17.4904+/- 0.019 mean_var=113.5682+/-22.675, 0's: 0 Z-trim(120.1): 149 B-trim: 0 in 0/53 Lambda= 0.120350 statistics sampled from 34673 (34826) to 34673 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.408), width: 16 Scan time: 7.990 The best scores are: opt bits E(85289) NP_077286 (OMIM: 615200) pleckstrin homology domai ( 279) 1915 342.6 4.9e-94 XP_011525611 (OMIM: 615200) PREDICTED: pleckstrin ( 279) 1915 342.6 4.9e-94 XP_005259313 (OMIM: 615200) PREDICTED: pleckstrin ( 364) 1915 342.7 5.8e-94 NP_078889 (OMIM: 615208) pleckstrin homology domai ( 249) 1002 184.0 2.4e-46 NP_056161 (OMIM: 270700,612012) zinc finger FYVE d (2539) 283 60.4 4e-08 NP_060821 (OMIM: 613520) FYVE, RhoGEF and PH domai (1430) 265 57.0 2.4e-07 XP_016876617 (OMIM: 270700,612012) PREDICTED: zinc (1739) 265 57.1 2.7e-07 XP_016876616 (OMIM: 270700,612012) PREDICTED: zinc (1770) 265 57.1 2.8e-07 XP_016876615 (OMIM: 270700,612012) PREDICTED: zinc (2042) 265 57.1 3e-07 XP_016876614 (OMIM: 270700,612012) PREDICTED: zinc (2503) 265 57.3 3.5e-07 XP_016876613 (OMIM: 270700,612012) PREDICTED: zinc (2545) 265 57.3 3.5e-07 NP_775829 (OMIM: 605091) FYVE, RhoGEF and PH domai ( 655) 255 54.8 4.9e-07 XP_016863994 (OMIM: 614176) PREDICTED: lateral sig ( 773) 244 53.0 2e-06 NP_001166130 (OMIM: 614176) lateral signaling targ ( 817) 244 53.0 2.1e-06 NP_001166127 (OMIM: 614176) lateral signaling targ ( 857) 244 53.1 2.2e-06 NP_066023 (OMIM: 614176) lateral signaling target ( 887) 244 53.1 2.2e-06 XP_016858334 (OMIM: 603755) PREDICTED: zinc finger (1167) 244 53.2 2.7e-06 NP_004790 (OMIM: 603755) zinc finger FYVE domain-c (1425) 244 53.3 3e-06 XP_011540739 (OMIM: 603755) PREDICTED: zinc finger (1425) 244 53.3 3e-06 NP_001291413 (OMIM: 609311,611104) FYVE, RhoGEF an ( 422) 234 51.0 4.6e-06 NP_001291412 (OMIM: 609311,611104) FYVE, RhoGEF an ( 471) 234 51.0 4.9e-06 XP_011518861 (OMIM: 609311,611104) PREDICTED: FYVE ( 511) 234 51.1 5.2e-06 XP_005253367 (OMIM: 609311,611104) PREDICTED: FYVE ( 518) 234 51.1 5.3e-06 XP_011518860 (OMIM: 609311,611104) PREDICTED: FYVE ( 567) 234 51.1 5.6e-06 XP_011518859 (OMIM: 609311,611104) PREDICTED: FYVE ( 582) 234 51.1 5.7e-06 XP_016874294 (OMIM: 609311,611104) PREDICTED: FYVE ( 582) 234 51.1 5.7e-06 NP_001317303 (OMIM: 609311,611104) FYVE, RhoGEF an ( 673) 234 51.2 6.2e-06 XP_005253366 (OMIM: 609311,611104) PREDICTED: FYVE ( 673) 234 51.2 6.2e-06 XP_005253365 (OMIM: 609311,611104) PREDICTED: FYVE ( 673) 234 51.2 6.2e-06 NP_001317302 (OMIM: 609311,611104) FYVE, RhoGEF an ( 673) 234 51.2 6.2e-06 XP_011518857 (OMIM: 609311,611104) PREDICTED: FYVE ( 766) 234 51.3 6.8e-06 XP_011518858 (OMIM: 609311,611104) PREDICTED: FYVE ( 766) 234 51.3 6.8e-06 NP_640334 (OMIM: 609311,611104) FYVE, RhoGEF and P ( 766) 234 51.3 6.8e-06 NP_001291410 (OMIM: 609311,611104) FYVE, RhoGEF an ( 851) 234 51.3 7.2e-06 XP_011518856 (OMIM: 609311,611104) PREDICTED: FYVE ( 864) 234 51.3 7.3e-06 NP_001291409 (OMIM: 609311,611104) FYVE, RhoGEF an ( 878) 234 51.3 7.4e-06 XP_016874292 (OMIM: 609311,611104) PREDICTED: FYVE ( 914) 234 51.4 7.6e-06 XP_005253361 (OMIM: 609311,611104) PREDICTED: FYVE ( 930) 234 51.4 7.7e-06 NP_015563 (OMIM: 603755) zinc finger FYVE domain-c (1366) 236 51.9 7.7e-06 XP_016865918 (OMIM: 605091) PREDICTED: FYVE, RhoGE ( 662) 231 50.7 8.8e-06 NP_076976 (OMIM: 613504) zinc finger FYVE domain-c ( 234) 223 48.7 1.2e-05 NP_001185882 (OMIM: 613504) zinc finger FYVE domai ( 252) 223 48.8 1.2e-05 XP_011537117 (OMIM: 605070) PREDICTED: early endos (1365) 232 51.2 1.2e-05 NP_003557 (OMIM: 605070) early endosome antigen 1 (1411) 232 51.2 1.3e-05 XP_016875507 (OMIM: 605070) PREDICTED: early endos (1417) 232 51.2 1.3e-05 XP_011537116 (OMIM: 605070) PREDICTED: early endos (1453) 232 51.2 1.3e-05 XP_016880786 (OMIM: 604375) PREDICTED: hepatocyte ( 768) 224 49.5 2.3e-05 NP_004703 (OMIM: 604375) hepatocyte growth factor- ( 777) 224 49.5 2.3e-05 XP_011523765 (OMIM: 604375) PREDICTED: hepatocyte ( 777) 224 49.5 2.3e-05 XP_016865384 (OMIM: 610327) PREDICTED: RUN and FYV ( 310) 210 46.6 6.8e-05 >>NP_077286 (OMIM: 615200) pleckstrin homology domain-co (279 aa) initn: 1915 init1: 1915 opt: 1915 Z-score: 1809.3 bits: 342.6 E(85289): 4.9e-94 Smith-Waterman score: 1915; 100.0% identity (100.0% similar) in 279 aa overlap (1-279:1-279) 10 20 30 40 50 60 pF1KB7 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG 190 200 210 220 230 240 250 260 270 pF1KB7 ASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS ::::::::::::::::::::::::::::::::::::::: NP_077 ASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS 250 260 270 >>XP_011525611 (OMIM: 615200) PREDICTED: pleckstrin homo (279 aa) initn: 1915 init1: 1915 opt: 1915 Z-score: 1809.3 bits: 342.6 E(85289): 4.9e-94 Smith-Waterman score: 1915; 100.0% identity (100.0% similar) in 279 aa overlap (1-279:1-279) 10 20 30 40 50 60 pF1KB7 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG 190 200 210 220 230 240 250 260 270 pF1KB7 ASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS ::::::::::::::::::::::::::::::::::::::: XP_011 ASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS 250 260 270 >>XP_005259313 (OMIM: 615200) PREDICTED: pleckstrin homo (364 aa) initn: 1915 init1: 1915 opt: 1915 Z-score: 1808.0 bits: 342.7 E(85289): 5.8e-94 Smith-Waterman score: 1915; 100.0% identity (100.0% similar) in 279 aa overlap (1-279:86-364) 10 20 30 pF1KB7 MVDHLANTEINSQRIAAVESCFGASGQPLA :::::::::::::::::::::::::::::: XP_005 WGERSGVRASEAESPGKRADVSWWSRQLETMVDHLANTEINSQRIAAVESCFGASGQPLA 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB7 LPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELL 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB7 PETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAAPWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAAPWI 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB7 PDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRE 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB7 LAAQQRQEEAEEQGAGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDWPSSVEFYAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAAQQRQEEAEEQGAGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDWPSSVEFYAS 300 310 320 330 340 350 pF1KB7 GVAWSAFHS ::::::::: XP_005 GVAWSAFHS 360 >>NP_078889 (OMIM: 615208) pleckstrin homology domain-co (249 aa) initn: 1064 init1: 958 opt: 1002 Z-score: 953.1 bits: 184.0 E(85289): 2.4e-46 Smith-Waterman score: 1002; 56.0% identity (78.6% similar) in 252 aa overlap (1-252:1-249) 10 20 30 40 50 60 pF1KB7 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND :::.:::.: :..::. ::.::::.::::..:::::.::::::: :::: : : :::::: NP_078 MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFND 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ :::::.::..:.:: .:::::::.::.. . . . .: :.::: :::.: ::.:::.. NP_078 ILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF ::..::..:: : .:. ::.:::: :.::. . .:::: ...:. ..:::::::::: NP_078 EWMNHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG :::. ::..::::: : ::::.:..:: :.: . : : : : . : :. NP_078 VVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSA---GDMATCQPARSDSYSQSLKSPLND 190 200 210 220 230 250 260 270 pF1KB7 ASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS :. ::::.. : NP_078 MSDDDDDDDSSD 240 >>NP_056161 (OMIM: 270700,612012) zinc finger FYVE domai (2539 aa) initn: 245 init1: 245 opt: 283 Z-score: 266.8 bits: 60.4 E(85289): 4e-08 Smith-Waterman score: 283; 29.5% identity (59.0% similar) in 156 aa overlap (71-225:1735-1885) 50 60 70 80 90 pF1KB7 VLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELL-PETLQAKNR .:. ::. .: :.:.. . :::: . NP_056 LVGQEIGFTMDEVDSLLSRYAEKALDFPYPQREKRSDSVIHLQEIVHQAADPETLPRSPS 1710 1720 1730 1740 1750 1760 100 110 120 130 140 150 pF1KB7 WMIKTAKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICM .. : . : : . :.. : ... . ::. .. :.::.. .::: NP_056 AEFSPAAPPGISSIHSPSLRER--SFPPTQPSQEFVPPATPPARHQ---WVPDETESICM 1770 1780 1790 1800 1810 160 170 180 190 200 210 pF1KB7 RCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEE : . .:. ..::::::.:: .::. :: ..... .:.:::. :: . .: NP_056 VCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENPARVCDQCYSYCNKDVPEEP 1820 1830 1840 1850 1860 1870 220 230 240 250 260 270 pF1KB7 AEEQGAGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS .:. : NP_056 SEKPEALDSSKNESPPYSFVVRVPKADEVEWILDLKEEENELVRSEFYYEQAPSASLCIA 1880 1890 1900 1910 1920 1930 >>NP_060821 (OMIM: 613520) FYVE, RhoGEF and PH domain-co (1430 aa) initn: 452 init1: 187 opt: 265 Z-score: 252.8 bits: 57.0 E(85289): 2.4e-07 Smith-Waterman score: 463; 35.7% identity (63.4% similar) in 238 aa overlap (11-229:1066-1295) 10 20 30 pF1KB7 MVDHLANTEINSQRIAAVESCFGASGQ-PLALPGRVLLGE : :.. .. .. .:. .. ::::.: : NP_060 DAGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQ--YSLNGHHEIVQPGRVFLKE 1040 1050 1060 1070 1080 1090 40 50 60 70 80 90 pF1KB7 GVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNR :.: : :: .::.:::::: :.: . : .. :. .... : . .. : .:. NP_060 GILMKLSRKVMQPRMFFLFNDALLYTTPV-QSGMYKLNNMLSLAGMKVRK-PTQEAYQNE 1100 1110 1120 1130 1140 1150 100 110 120 130 140 pF1KB7 WMIKTAKKSFVVSAASATERQEW---ISH-IEECVRRQL-----RATGRPPST--EHAAP :.....::..::.:::::.:: ::. ::: ..... :. . : :...: NP_060 LKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADSENKEEVSP 1160 1170 1180 1190 1200 1210 150 160 170 180 190 200 pF1KB7 -------WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPV :::: . .:: :: ..:. :::::: :: .:: :: ... : :. .:. NP_060 LGSKAPIWIPDTRATMCMICT-SEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPA 1220 1230 1240 1250 1260 1270 210 220 230 240 250 260 pF1KB7 RVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDW ::: :..:: :. .. . :::: NP_060 RVCEHCFQEL---QKLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEV 1280 1290 1300 1310 1320 >>XP_016876617 (OMIM: 270700,612012) PREDICTED: zinc fin (1739 aa) initn: 245 init1: 245 opt: 265 Z-score: 251.8 bits: 57.1 E(85289): 2.7e-07 Smith-Waterman score: 265; 28.5% identity (58.3% similar) in 151 aa overlap (76-225:940-1085) 50 60 70 80 90 100 pF1KB7 CRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELL-PETLQAKNRWMIKT .. .: :.:.. . :::: . .. XP_016 EVDSLLSRYAEKALDFPYPQREKRSAFSLSTDSVIHLQEIVHQAADPETLPRSPSAEFSP 910 920 930 940 950 960 110 120 130 140 150 160 pF1KB7 AKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQT : . : : . :.. : ... . ::. .. :.::.. .::: : . XP_016 AAPPGISSIHSPSLRER--SFPPTQPSQEFVPPATPPARHQ---WVPDETESICMVCCRE 970 980 990 1000 1010 1020 170 180 190 200 210 220 pF1KB7 RFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQG .:. ..::::::.:: .::. :: ..... .:.:::. :: . .: .:. XP_016 HFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENPARVCDQCYSYCNKDVPEEPSEKPE 1030 1040 1050 1060 1070 1080 230 240 250 260 270 pF1KB7 AGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS : XP_016 ALDSSKNESPPYSFVVRVPKADEVEWILDLKEEENELVRSEFYYEQAPSASLCIAILNLH 1090 1100 1110 1120 1130 1140 >>XP_016876616 (OMIM: 270700,612012) PREDICTED: zinc fin (1770 aa) initn: 245 init1: 245 opt: 265 Z-score: 251.7 bits: 57.1 E(85289): 2.8e-07 Smith-Waterman score: 265; 28.5% identity (58.3% similar) in 151 aa overlap (76-225:971-1116) 50 60 70 80 90 100 pF1KB7 CRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELL-PETLQAKNRWMIKT .. .: :.:.. . :::: . .. XP_016 EVDSLLSRYAEKALDFPYPQREKRSAFSLSTDSVIHLQEIVHQAADPETLPRSPSAEFSP 950 960 970 980 990 1000 110 120 130 140 150 160 pF1KB7 AKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQT : . : : . :.. : ... . ::. .. :.::.. .::: : . XP_016 AAPPGISSIHSPSLRER--SFPPTQPSQEFVPPATPPARHQ---WVPDETESICMVCCRE 1010 1020 1030 1040 1050 170 180 190 200 210 220 pF1KB7 RFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQG .:. ..::::::.:: .::. :: ..... .:.:::. :: . .: .:. XP_016 HFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENPARVCDQCYSYCNKDVPEEPSEKPE 1060 1070 1080 1090 1100 1110 230 240 250 260 270 pF1KB7 AGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS : XP_016 ALDSSKNESPPYSFVVRVPKADEVEWILDLKEEENELVRSEFYYEQAPSASLCIAILNLH 1120 1130 1140 1150 1160 1170 >>XP_016876615 (OMIM: 270700,612012) PREDICTED: zinc fin (2042 aa) initn: 245 init1: 245 opt: 265 Z-score: 251.0 bits: 57.1 E(85289): 3e-07 Smith-Waterman score: 265; 28.5% identity (58.3% similar) in 151 aa overlap (76-225:1243-1388) 50 60 70 80 90 100 pF1KB7 CRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELL-PETLQAKNRWMIKT .. .: :.:.. . :::: . .. XP_016 EVDSLLSRYAEKALDFPYPQREKRSAFSLSTDSVIHLQEIVHQAADPETLPRSPSAEFSP 1220 1230 1240 1250 1260 1270 110 120 130 140 150 160 pF1KB7 AKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQT : . : : . :.. : ... . ::. .. :.::.. .::: : . XP_016 AAPPGISSIHSPSLRER--SFPPTQPSQEFVPPATPPARHQ---WVPDETESICMVCCRE 1280 1290 1300 1310 1320 170 180 190 200 210 220 pF1KB7 RFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQG .:. ..::::::.:: .::. :: ..... .:.:::. :: . .: .:. XP_016 HFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENPARVCDQCYSYCNKDVPEEPSEKPE 1330 1340 1350 1360 1370 1380 230 240 250 260 270 pF1KB7 AGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS : XP_016 ALDSSKNESPPYSFVVRVPKADEVEWILDLKEEENELVRSEFYYEQAPSASLCIAILNLH 1390 1400 1410 1420 1430 1440 >>XP_016876614 (OMIM: 270700,612012) PREDICTED: zinc fin (2503 aa) initn: 245 init1: 245 opt: 265 Z-score: 250.0 bits: 57.3 E(85289): 3.5e-07 Smith-Waterman score: 265; 28.5% identity (58.3% similar) in 151 aa overlap (76-225:1746-1891) 50 60 70 80 90 100 pF1KB7 CRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELL-PETLQAKNRWMIKT .. .: :.:.. . :::: . .. XP_016 EVDSLLSRYAEKALDFPYPQREKRSAFSLSTDSVIHLQEIVHQAADPETLPRSPSAEFSP 1720 1730 1740 1750 1760 1770 110 120 130 140 150 160 pF1KB7 AKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQT : . : : . :.. : ... . ::. .. :.::.. .::: : . XP_016 AAPPGISSIHSPSLRER--SFPPTQPSQEFVPPATPPARHQ---WVPDETESICMVCCRE 1780 1790 1800 1810 1820 1830 170 180 190 200 210 220 pF1KB7 RFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQG .:. ..::::::.:: .::. :: ..... .:.:::. :: . .: .:. XP_016 HFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRENPARVCDQCYSYCNKDVPEEPSEKPE 1840 1850 1860 1870 1880 1890 230 240 250 260 270 pF1KB7 AGSPGQPAHLARPICGASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS : XP_016 ALDSSKNESPPYSFVVRVPKADEVEWILDLKEEENELVRSEFYYEQAPSASLCIAILNLH 1900 1910 1920 1930 1940 1950 279 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:52:28 2016 done: Fri Nov 4 04:52:29 2016 Total Scan time: 7.990 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]