FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7119, 287 aa 1>>>pF1KB7119 287 - 287 aa - 287 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5082+/-0.000442; mu= 9.9430+/- 0.027 mean_var=111.3401+/-22.399, 0's: 0 Z-trim(113.6): 76 B-trim: 100 in 1/49 Lambda= 0.121548 statistics sampled from 22899 (22975) to 22899 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.269), width: 16 Scan time: 7.050 The best scores are: opt bits E(85289) XP_011534519 (OMIM: 603552,605014) PREDICTED: synt ( 287) 1888 341.9 8.3e-94 XP_011534520 (OMIM: 603552,605014) PREDICTED: synt ( 287) 1888 341.9 8.3e-94 XP_016866889 (OMIM: 603552,605014) PREDICTED: synt ( 287) 1888 341.9 8.3e-94 NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo ( 287) 1888 341.9 8.3e-94 XP_011534516 (OMIM: 603552,605014) PREDICTED: synt ( 287) 1888 341.9 8.3e-94 XP_011534515 (OMIM: 603552,605014) PREDICTED: synt ( 313) 1888 342.0 8.8e-94 XP_016878382 (OMIM: 601485,616172) PREDICTED: synt ( 282) 565 109.9 5.6e-24 NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo ( 288) 565 109.9 5.7e-24 NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Hom ( 287) 546 106.6 5.7e-23 XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2 ( 319) 546 106.6 6.2e-23 XP_005253614 (OMIM: 132350) PREDICTED: syntaxin-2 ( 277) 544 106.2 7.1e-23 XP_016874471 (OMIM: 132350) PREDICTED: syntaxin-2 ( 309) 544 106.3 7.7e-23 NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Hom ( 288) 542 105.9 9.3e-23 XP_016874470 (OMIM: 132350) PREDICTED: syntaxin-2 ( 317) 542 105.9 1e-22 XP_016874467 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 542 105.9 1e-22 XP_016874468 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 542 105.9 1e-22 XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 ( 260) 511 100.4 3.7e-21 NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Ho ( 288) 500 98.5 1.5e-20 XP_016873682 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 472 93.6 4.5e-19 XP_016873681 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 472 93.6 4.5e-19 XP_005274255 (OMIM: 600876) PREDICTED: syntaxin-3 ( 287) 472 93.6 4.6e-19 XP_016873683 (OMIM: 600876) PREDICTED: syntaxin-3 ( 269) 462 91.8 1.5e-18 NP_001171511 (OMIM: 600876) syntaxin-3 isoform 2 [ ( 277) 462 91.9 1.5e-18 XP_016873680 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 462 91.9 1.5e-18 XP_016873677 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 462 91.9 1.5e-18 XP_016873679 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 462 91.9 1.5e-18 XP_016873678 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 462 91.9 1.5e-18 NP_004168 (OMIM: 600876) syntaxin-3 isoform 1 [Hom ( 289) 462 91.9 1.6e-18 XP_005274252 (OMIM: 600876) PREDICTED: syntaxin-3 ( 289) 462 91.9 1.6e-18 XP_016874474 (OMIM: 132350) PREDICTED: syntaxin-2 ( 213) 456 90.7 2.5e-18 XP_016874473 (OMIM: 132350) PREDICTED: syntaxin-2 ( 214) 452 90.0 4.2e-18 XP_011543523 (OMIM: 600876) PREDICTED: syntaxin-3 ( 192) 411 82.8 5.6e-16 NP_001159375 (OMIM: 186590) syntaxin-1A isoform 2 ( 251) 408 82.4 9.9e-16 XP_016868056 (OMIM: 186590) PREDICTED: syntaxin-1A ( 329) 408 82.4 1.2e-15 NP_004595 (OMIM: 186591) syntaxin-4 isoform 3 [Hom ( 297) 393 79.8 7e-15 XP_005255578 (OMIM: 186591) PREDICTED: syntaxin-4 ( 293) 373 76.3 7.9e-14 NP_001259025 (OMIM: 186591) syntaxin-4 isoform 2 [ ( 295) 373 76.3 7.9e-14 XP_016873684 (OMIM: 600876) PREDICTED: syntaxin-3 ( 244) 371 75.9 8.7e-14 XP_005274257 (OMIM: 600876) PREDICTED: syntaxin-3 ( 252) 371 75.9 8.9e-14 NP_001259024 (OMIM: 186591) syntaxin-4 isoform 1 [ ( 219) 348 71.8 1.3e-12 XP_016873685 (OMIM: 600876) PREDICTED: syntaxin-3 ( 155) 320 66.8 3e-11 XP_011544227 (OMIM: 186591) PREDICTED: syntaxin-4 ( 154) 280 59.8 3.8e-09 XP_016874475 (OMIM: 132350) PREDICTED: syntaxin-2 ( 200) 220 49.3 7e-06 XP_016874477 (OMIM: 132350) PREDICTED: syntaxin-2 ( 167) 213 48.0 1.4e-05 XP_016874476 (OMIM: 132350) PREDICTED: syntaxin-2 ( 199) 213 48.1 1.6e-05 NP_803173 (OMIM: 606892) syntaxin-12 [Homo sapiens ( 276) 183 42.9 0.00081 NP_001313509 (OMIM: 603217) syntaxin-7 isoform b [ ( 239) 164 39.6 0.0072 XP_011534480 (OMIM: 603217) PREDICTED: syntaxin-7 ( 239) 164 39.6 0.0072 >>XP_011534519 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa) initn: 1888 init1: 1888 opt: 1888 Z-score: 1805.2 bits: 341.9 E(85289): 8.3e-94 Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 190 200 210 220 230 240 250 260 270 280 pF1KB7 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 250 260 270 280 >>XP_011534520 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa) initn: 1888 init1: 1888 opt: 1888 Z-score: 1805.2 bits: 341.9 E(85289): 8.3e-94 Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 190 200 210 220 230 240 250 260 270 280 pF1KB7 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 250 260 270 280 >>XP_016866889 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa) initn: 1888 init1: 1888 opt: 1888 Z-score: 1805.2 bits: 341.9 E(85289): 8.3e-94 Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 190 200 210 220 230 240 250 260 270 280 pF1KB7 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 250 260 270 280 >>NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo sapi (287 aa) initn: 1888 init1: 1888 opt: 1888 Z-score: 1805.2 bits: 341.9 E(85289): 8.3e-94 Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 190 200 210 220 230 240 250 260 270 280 pF1KB7 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK ::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 250 260 270 280 >>XP_011534516 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa) initn: 1888 init1: 1888 opt: 1888 Z-score: 1805.2 bits: 341.9 E(85289): 8.3e-94 Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:1-287) 10 20 30 40 50 60 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 190 200 210 220 230 240 250 260 270 280 pF1KB7 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 250 260 270 280 >>XP_011534515 (OMIM: 603552,605014) PREDICTED: syntaxin (313 aa) initn: 1888 init1: 1888 opt: 1888 Z-score: 1804.6 bits: 342.0 E(85289): 8.8e-94 Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 287 aa overlap (1-287:27-313) 10 20 30 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIV :::::::::::::::::::::::::::::::::: XP_011 MEQPQGDEMDEGEEEEKKARSQPQSKMKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 FETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 ARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 DNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHREL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 LRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNP 250 260 270 280 290 300 280 pF1KB7 CRTLCCFCCPCLK ::::::::::::: XP_011 CRTLCCFCCPCLK 310 >>XP_016878382 (OMIM: 601485,616172) PREDICTED: syntaxin (282 aa) initn: 565 init1: 456 opt: 565 Z-score: 551.5 bits: 109.9 E(85289): 5.6e-24 Smith-Waterman score: 565; 34.5% identity (71.2% similar) in 267 aa overlap (21-286:7-268) 10 20 30 40 50 60 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA :.::: . : : ::... .......:. . : XP_016 MEPRAKDSDDEEEVVHVD----RDHFMDEFFEQVEEIRGCIEKLSE 10 20 30 40 70 80 90 100 110 120 pF1KB7 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP ::... ::.. .:.. . :.. .... :: .. .. ::.:... : :. . XP_016 DVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM :: :: ..:...:. : ..: .:: .. : :: :: :::::::: :. ......::: XP_016 -SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD .:.:: .:.... : . .. ::::::.:: :...::. ::..:..:..::.:::.:.. XP_016 LESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGE 170 180 190 200 210 220 250 260 270 280 pF1KB7 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNP-CRTLCCFCCPCLK .. :: ::...:::. .: ....:::.:. : . . .:: : XP_016 MIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLG 230 240 250 260 270 280 XP_016 L >>NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo sapi (288 aa) initn: 588 init1: 456 opt: 565 Z-score: 551.3 bits: 109.9 E(85289): 5.7e-24 Smith-Waterman score: 573; 34.1% identity (69.0% similar) in 287 aa overlap (1-286:1-274) 10 20 30 40 50 60 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA :::: :: .. :.::: . : : ::... .......:. . : NP_443 MKDRTQEL--------RSAKDSDDEEEVVHVD----RDHFMDEFFEQVEEIRGCIEKLSE 10 20 30 40 70 80 90 100 110 120 pF1KB7 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP ::... ::.. .:.. . :.. .... :: .. .. ::.:... : :. . NP_443 DVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM :: :: ..:...:. : ..: .:: .. : :: :: :::::::: :. ......::: NP_443 -SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDM 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD .:.:: .:.... : . .. ::::::.:: :...::. ::..:..:..::.:::.:.. NP_443 LESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGE 170 180 190 200 210 220 250 260 270 280 pF1KB7 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNP-CRTLCCFCCPCLK .. :: ::...:::. .: ....:::.:. : . . .:: : NP_443 MIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLG 230 240 250 260 270 280 NP_443 L >>NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Homo sa (287 aa) initn: 489 init1: 451 opt: 546 Z-score: 533.3 bits: 106.6 E(85289): 5.7e-23 Smith-Waterman score: 557; 33.5% identity (70.8% similar) in 284 aa overlap (1-283:1-270) 10 20 30 40 50 60 pF1KB7 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA :.::: .: :. ::: .: : ::...........:.. . .. NP_001 MRDRLPDLTACRKN-----DDGDTV-------VVVEKDHFMDDFFHQVEEIRNSIDKITQ 10 20 30 40 70 80 90 100 110 120 pF1KB7 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP :... :... .:.. ..::.. ... : :: .. :. ::.:... . :. : NP_001 YVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDES--GN 50 60 70 80 90 100 130 140 150 160 170 pF1KB7 HSAVA-RISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIED ...: :: :.:...:. : .:: .::.:. :. : :::::::: :. .. :..:. NP_001 RTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEE 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 MFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQA :.:.:: ..:. ....: . .: :::::::::.....::. ::..::.:..::..:: :. NP_001 MLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQG 170 180 190 200 210 220 240 250 260 270 280 pF1KB7 DTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK . .: :: ::....::. .:: ...::..:. : . . . : NP_001 EMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 230 240 250 260 270 280 NP_001 S >>XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2 isof (319 aa) initn: 489 init1: 451 opt: 546 Z-score: 532.7 bits: 106.6 E(85289): 6.2e-23 Smith-Waterman score: 546; 34.1% identity (75.0% similar) in 252 aa overlap (33-283:53-302) 10 20 30 40 50 60 pF1KB7 DRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADV .: : ::...........:.. . .. : XP_016 VICALKPQYSAWCLIQSTCQCRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYV 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB7 KRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHS ... :... .:.. ..::.. ... : :: .. :. ::.:... . :. : .. XP_016 EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDES--GNRT 90 100 110 120 130 140 130 140 150 160 170 180 pF1KB7 AVA-RISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMF .: :: :.:...:. : .:: .::.:. :. : :::::::: :. .. :..:.:. XP_016 SVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEML 150 160 170 180 190 200 190 200 210 220 230 240 pF1KB7 EQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADT :.:: ..:. ....: . .: :::::::::.....::. ::..::.:..::..:: :.. XP_016 ESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEM 210 220 230 240 250 260 250 260 270 280 pF1KB7 LNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK .: :: ::....::. .:: ...::..:. : . . . : XP_016 INNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 270 280 290 300 310 287 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:54:52 2016 done: Fri Nov 4 04:54:53 2016 Total Scan time: 7.050 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]