FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7120, 294 aa
1>>>pF1KB7120 294 - 294 aa - 294 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5235+/-0.000481; mu= 5.4463+/- 0.030
mean_var=165.1256+/-32.067, 0's: 0 Z-trim(113.6): 58 B-trim: 46 in 1/55
Lambda= 0.099808
statistics sampled from 22987 (23045) to 22987 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.27), width: 16
Scan time: 6.990
The best scores are: opt bits E(85289)
XP_011534520 (OMIM: 603552,605014) PREDICTED: synt ( 287) 727 116.9 4.8e-26
XP_011534519 (OMIM: 603552,605014) PREDICTED: synt ( 287) 727 116.9 4.8e-26
XP_016866889 (OMIM: 603552,605014) PREDICTED: synt ( 287) 727 116.9 4.8e-26
XP_011534516 (OMIM: 603552,605014) PREDICTED: synt ( 287) 727 116.9 4.8e-26
NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo ( 287) 727 116.9 4.8e-26
XP_011534515 (OMIM: 603552,605014) PREDICTED: synt ( 313) 727 116.9 5.1e-26
NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Ho ( 288) 467 79.4 9e-15
XP_016878382 (OMIM: 601485,616172) PREDICTED: synt ( 282) 464 79.0 1.2e-14
NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo ( 288) 464 79.0 1.2e-14
NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Hom ( 287) 450 77.0 4.9e-14
XP_016874470 (OMIM: 132350) PREDICTED: syntaxin-2 ( 317) 450 77.0 5.3e-14
XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2 ( 319) 450 77.0 5.3e-14
XP_005253614 (OMIM: 132350) PREDICTED: syntaxin-2 ( 277) 447 76.5 6.4e-14
NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Hom ( 288) 447 76.5 6.6e-14
XP_016874471 (OMIM: 132350) PREDICTED: syntaxin-2 ( 309) 447 76.6 6.9e-14
XP_016874468 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 447 76.6 7.1e-14
XP_016874467 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 447 76.6 7.1e-14
XP_016873681 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 441 75.7 1.2e-13
XP_016873682 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 441 75.7 1.2e-13
XP_005274255 (OMIM: 600876) PREDICTED: syntaxin-3 ( 287) 441 75.7 1.2e-13
XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 ( 260) 433 74.5 2.5e-13
XP_016873683 (OMIM: 600876) PREDICTED: syntaxin-3 ( 269) 429 73.9 3.8e-13
NP_001171511 (OMIM: 600876) syntaxin-3 isoform 2 [ ( 277) 429 73.9 3.9e-13
XP_016873679 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 429 73.9 3.9e-13
XP_016873680 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 429 73.9 3.9e-13
XP_016873677 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 429 73.9 3.9e-13
XP_016873678 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 429 73.9 3.9e-13
XP_005274252 (OMIM: 600876) PREDICTED: syntaxin-3 ( 289) 429 73.9 4e-13
NP_004168 (OMIM: 600876) syntaxin-3 isoform 1 [Hom ( 289) 429 73.9 4e-13
NP_001159375 (OMIM: 186590) syntaxin-1A isoform 2 ( 251) 395 69.0 1.1e-11
XP_011543523 (OMIM: 600876) PREDICTED: syntaxin-3 ( 192) 392 68.5 1.2e-11
XP_016868056 (OMIM: 186590) PREDICTED: syntaxin-1A ( 329) 395 69.1 1.3e-11
NP_004595 (OMIM: 186591) syntaxin-4 isoform 3 [Hom ( 297) 390 68.3 2e-11
XP_016874474 (OMIM: 132350) PREDICTED: syntaxin-2 ( 213) 383 67.2 3.1e-11
XP_016874473 (OMIM: 132350) PREDICTED: syntaxin-2 ( 214) 380 66.8 4.2e-11
XP_005255578 (OMIM: 186591) PREDICTED: syntaxin-4 ( 293) 366 64.9 2.2e-10
NP_001259025 (OMIM: 186591) syntaxin-4 isoform 2 [ ( 295) 366 64.9 2.2e-10
XP_016873684 (OMIM: 600876) PREDICTED: syntaxin-3 ( 244) 353 62.9 6.9e-10
XP_005274257 (OMIM: 600876) PREDICTED: syntaxin-3 ( 252) 353 63.0 7.1e-10
NP_001259024 (OMIM: 186591) syntaxin-4 isoform 1 [ ( 219) 319 58.0 1.9e-08
XP_016873685 (OMIM: 600876) PREDICTED: syntaxin-3 ( 155) 316 57.5 2e-08
XP_011544227 (OMIM: 186591) PREDICTED: syntaxin-4 ( 154) 250 47.9 1.4e-05
XP_011534480 (OMIM: 603217) PREDICTED: syntaxin-7 ( 239) 199 40.8 0.0032
NP_001313509 (OMIM: 603217) syntaxin-7 isoform b [ ( 239) 199 40.8 0.0032
NP_803173 (OMIM: 606892) syntaxin-12 [Homo sapiens ( 276) 194 40.1 0.0059
>>XP_011534520 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa)
initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26
Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285)
10 20 30 40 50 60
pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES
::::: :: ..::.. . . ... .. ...: . . : ..:. .:.
XP_011 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE
10 20 30 40 50
70 80 90 100 110
pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS
. :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . .
XP_011 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE
:...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.:
XP_011 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL
....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...:
XP_011 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK
::.:....: ::..:..: .:....: . ::.:...::::.:::.::::
XP_011 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK
240 250 260 270 280
>>XP_011534519 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa)
initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26
Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285)
10 20 30 40 50 60
pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES
::::: :: ..::.. . . ... .. ...: . . : ..:. .:.
XP_011 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE
10 20 30 40 50
70 80 90 100 110
pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS
. :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . .
XP_011 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE
:...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.:
XP_011 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL
....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...:
XP_011 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK
::.:....: ::..:..: .:....: . ::.:...::::.:::.::::
XP_011 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK
240 250 260 270 280
>>XP_016866889 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa)
initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26
Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285)
10 20 30 40 50 60
pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES
::::: :: ..::.. . . ... .. ...: . . : ..:. .:.
XP_016 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE
10 20 30 40 50
70 80 90 100 110
pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS
. :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . .
XP_016 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE
:...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.:
XP_016 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL
....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...:
XP_016 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK
::.:....: ::..:..: .:....: . ::.:...::::.:::.::::
XP_016 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK
240 250 260 270 280
>>XP_011534516 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa)
initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26
Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285)
10 20 30 40 50 60
pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES
::::: :: ..::.. . . ... .. ...: . . : ..:. .:.
XP_011 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE
10 20 30 40 50
70 80 90 100 110
pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS
. :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . .
XP_011 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE
:...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.:
XP_011 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL
....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...:
XP_011 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK
::.:....: ::..:..: .:....: . ::.:...::::.:::.::::
XP_011 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK
240 250 260 270 280
>>NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo sapi (287 aa)
initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26
Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285)
10 20 30 40 50 60
pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES
::::: :: ..::.. . . ... .. ...: . . : ..:. .:.
NP_003 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE
10 20 30 40 50
70 80 90 100 110
pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS
. :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . .
NP_003 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE
:...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.:
NP_003 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL
....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...:
NP_003 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK
::.:....: ::..:..: .:....: . ::.:...::::.:::.::::
NP_003 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK
240 250 260 270 280
>>XP_011534515 (OMIM: 603552,605014) PREDICTED: syntaxin (313 aa)
initn: 675 init1: 579 opt: 727 Z-score: 588.1 bits: 116.9 E(85289): 5.1e-26
Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:27-311)
10 20 30
pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVF
::::: :: ..::.. . . ...
XP_011 MEQPQGDEMDEGEEEEKKARSQPQSKMKDRLAEL------LDLSKQYDQQFPDGDDEFDS
10 20 30 40 50
40 50 60 70 80 90
pF1KB7 LQQAVIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRES-T
.. ...: . . : ..:. .:. . :. .:...:.:. ...::::.: .::.. .
XP_011 PHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNS
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB7 ITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYND
:.: :: ..: :. .: . . . .:...:: :.:.:: ..:. :. ::. : ::.
XP_011 IAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 TIAAKQEKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIE
. ....:: : ::::. :::.: ....::..::::.::.:.::.... ..: :.:::
XP_011 AEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIE
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 QRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVK
.::.::. ::..:.:...::.:...:::.:....: ::..:..: .:....: . ::.
XP_011 SRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQ
240 250 260 270 280 290
280 290
pF1KB7 YKKRNPCRVLCCWCCPCCSSK
:...::::.:::.::::
XP_011 YEEKNPCRTLCCFCCPCLK
300 310
>>NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Homo s (288 aa)
initn: 454 init1: 390 opt: 467 Z-score: 386.2 bits: 79.4 E(85289): 9e-15
Smith-Waterman score: 481; 31.1% identity (67.5% similar) in 283 aa overlap (8-288:1-272)
10 20 30 40 50 60
pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES
.:.::.:.. ..:: ... : :: .:. .. ........
NP_004 MKDRTQELRTAKDSD------DDDDV----AVTVDRDRFMDEFFEQVEEIRGF
10 20 30 40
70 80 90 100 110
pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKS
:...:.::.. .......:: :.: . ..:: :. . .:... . ...
NP_004 IDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE
: : ::. :: :.::... :.: ..: :: : . .:.:: : ::::..:. .
NP_004 EGLNR-SSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL
:...:::..:. .: ... . .:.: ::::: ::.:...:::.:..:.:.:.....:
NP_004 EELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAML
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCCPCCSSK
:: ::: :. ::..:. . .::. . ::::. : ... ::
NP_004 VESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIAST
230 240 250 260 270 280
NP_004 VGGIFA
>>XP_016878382 (OMIM: 601485,616172) PREDICTED: syntaxin (282 aa)
initn: 419 init1: 389 opt: 464 Z-score: 384.0 bits: 79.0 E(85289): 1.2e-14
Smith-Waterman score: 464; 30.6% identity (69.4% similar) in 255 aa overlap (36-288:12-265)
10 20 30 40 50 60
pF1KB7 QELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLA
...: .:. .. ........ :..:.
XP_016 MEPRAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLS
10 20 30 40
70 80 90 100 110 120
pF1KB7 DNVQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENG
..:.. .:.....:. :.: .: .:: :. . .:. . . ... : :
XP_016 EDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNR
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 PSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVND
::. :: :.::... :.: ..: :: : . ...:: : ::::..:. ..:...:
XP_016 -SSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELED
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 MLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQG
::..:: .:.... . ..:: :.::: ::.:...::..:..:.:.:.....::: ::
XP_016 MLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQG
170 180 190 200 210 220
250 260 270 280 290
pF1KB7 ESINNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCCPCCSSK
: :. ::..:. . .::. . ::::. : ... ::
XP_016 EMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTL
230 240 250 260 270 280
XP_016 GL
>>NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo sapi (288 aa)
initn: 453 init1: 389 opt: 464 Z-score: 383.9 bits: 79.0 E(85289): 1.2e-14
Smith-Waterman score: 479; 30.4% identity (67.8% similar) in 283 aa overlap (8-288:1-271)
10 20 30 40 50 60
pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES
.:.::.:.. ..:: . ::. : . .:. .. ........
NP_443 MKDRTQELRSAKDS-----DDEEEVVHV------DRDHFMDEFFEQVEEIRGC
10 20 30 40
70 80 90 100 110
pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKS
:..:...:.. .:.....:. :.: .: .:: :. . .:. . . ...
NP_443 IEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE
: : ::. :: :.::... :.: ..: :: : . ...:: : ::::..:. ..
NP_443 EGLNR-SSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL
:...:::..:: .:.... . ..:: :.::: ::.:...::..:..:.:.:.....:
NP_443 EELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAML
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCCPCCSSK
:: ::: :. ::..:. . .::. . ::::. : ... ::
NP_443 VESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASS
230 240 250 260 270 280
NP_443 IGGTLGL
>>NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Homo sa (287 aa)
initn: 422 init1: 377 opt: 450 Z-score: 373.0 bits: 77.0 E(85289): 4.9e-14
Smith-Waterman score: 450; 29.5% identity (72.1% similar) in 251 aa overlap (39-288:21-270)
10 20 30 40 50 60
pF1KB7 KQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADNV
:. :.. . .:.......::..... :
NP_001 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYV
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 QKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSS
.. .... .... . .:.: ..:::: :. : .:. . . ..: : .:
NP_001 EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNR-TS
60 70 80 90 100
130 140 150 160 170 180
pF1KB7 VVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDMLH
: :: ..::... :.: . : ::.. . .:. : : ::::..:. .......::.
NP_001 VDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLE
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 QGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESI
.:: .:. ..... .::. :.:::.:::....::..:..:...:......:: ::: :
NP_001 SGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMI
170 180 190 200 210 220
250 260 270 280 290
pF1KB7 NNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK
:::: .: .. .::...::. :.::... ... :
NP_001 NNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS
230 240 250 260 270 280
294 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 04:55:22 2016 done: Fri Nov 4 04:55:23 2016
Total Scan time: 6.990 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]