FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7120, 294 aa 1>>>pF1KB7120 294 - 294 aa - 294 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5235+/-0.000481; mu= 5.4463+/- 0.030 mean_var=165.1256+/-32.067, 0's: 0 Z-trim(113.6): 58 B-trim: 46 in 1/55 Lambda= 0.099808 statistics sampled from 22987 (23045) to 22987 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.27), width: 16 Scan time: 6.990 The best scores are: opt bits E(85289) XP_011534520 (OMIM: 603552,605014) PREDICTED: synt ( 287) 727 116.9 4.8e-26 XP_011534519 (OMIM: 603552,605014) PREDICTED: synt ( 287) 727 116.9 4.8e-26 XP_016866889 (OMIM: 603552,605014) PREDICTED: synt ( 287) 727 116.9 4.8e-26 XP_011534516 (OMIM: 603552,605014) PREDICTED: synt ( 287) 727 116.9 4.8e-26 NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo ( 287) 727 116.9 4.8e-26 XP_011534515 (OMIM: 603552,605014) PREDICTED: synt ( 313) 727 116.9 5.1e-26 NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Ho ( 288) 467 79.4 9e-15 XP_016878382 (OMIM: 601485,616172) PREDICTED: synt ( 282) 464 79.0 1.2e-14 NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo ( 288) 464 79.0 1.2e-14 NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Hom ( 287) 450 77.0 4.9e-14 XP_016874470 (OMIM: 132350) PREDICTED: syntaxin-2 ( 317) 450 77.0 5.3e-14 XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2 ( 319) 450 77.0 5.3e-14 XP_005253614 (OMIM: 132350) PREDICTED: syntaxin-2 ( 277) 447 76.5 6.4e-14 NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Hom ( 288) 447 76.5 6.6e-14 XP_016874471 (OMIM: 132350) PREDICTED: syntaxin-2 ( 309) 447 76.6 6.9e-14 XP_016874468 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 447 76.6 7.1e-14 XP_016874467 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 447 76.6 7.1e-14 XP_016873681 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 441 75.7 1.2e-13 XP_016873682 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 441 75.7 1.2e-13 XP_005274255 (OMIM: 600876) PREDICTED: syntaxin-3 ( 287) 441 75.7 1.2e-13 XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 ( 260) 433 74.5 2.5e-13 XP_016873683 (OMIM: 600876) PREDICTED: syntaxin-3 ( 269) 429 73.9 3.8e-13 NP_001171511 (OMIM: 600876) syntaxin-3 isoform 2 [ ( 277) 429 73.9 3.9e-13 XP_016873679 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 429 73.9 3.9e-13 XP_016873680 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 429 73.9 3.9e-13 XP_016873677 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 429 73.9 3.9e-13 XP_016873678 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 429 73.9 3.9e-13 XP_005274252 (OMIM: 600876) PREDICTED: syntaxin-3 ( 289) 429 73.9 4e-13 NP_004168 (OMIM: 600876) syntaxin-3 isoform 1 [Hom ( 289) 429 73.9 4e-13 NP_001159375 (OMIM: 186590) syntaxin-1A isoform 2 ( 251) 395 69.0 1.1e-11 XP_011543523 (OMIM: 600876) PREDICTED: syntaxin-3 ( 192) 392 68.5 1.2e-11 XP_016868056 (OMIM: 186590) PREDICTED: syntaxin-1A ( 329) 395 69.1 1.3e-11 NP_004595 (OMIM: 186591) syntaxin-4 isoform 3 [Hom ( 297) 390 68.3 2e-11 XP_016874474 (OMIM: 132350) PREDICTED: syntaxin-2 ( 213) 383 67.2 3.1e-11 XP_016874473 (OMIM: 132350) PREDICTED: syntaxin-2 ( 214) 380 66.8 4.2e-11 XP_005255578 (OMIM: 186591) PREDICTED: syntaxin-4 ( 293) 366 64.9 2.2e-10 NP_001259025 (OMIM: 186591) syntaxin-4 isoform 2 [ ( 295) 366 64.9 2.2e-10 XP_016873684 (OMIM: 600876) PREDICTED: syntaxin-3 ( 244) 353 62.9 6.9e-10 XP_005274257 (OMIM: 600876) PREDICTED: syntaxin-3 ( 252) 353 63.0 7.1e-10 NP_001259024 (OMIM: 186591) syntaxin-4 isoform 1 [ ( 219) 319 58.0 1.9e-08 XP_016873685 (OMIM: 600876) PREDICTED: syntaxin-3 ( 155) 316 57.5 2e-08 XP_011544227 (OMIM: 186591) PREDICTED: syntaxin-4 ( 154) 250 47.9 1.4e-05 XP_011534480 (OMIM: 603217) PREDICTED: syntaxin-7 ( 239) 199 40.8 0.0032 NP_001313509 (OMIM: 603217) syntaxin-7 isoform b [ ( 239) 199 40.8 0.0032 NP_803173 (OMIM: 606892) syntaxin-12 [Homo sapiens ( 276) 194 40.1 0.0059 >>XP_011534520 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa) initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26 Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285) 10 20 30 40 50 60 pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES ::::: :: ..::.. . . ... .. ...: . . : ..:. .:. XP_011 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE 10 20 30 40 50 70 80 90 100 110 pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS . :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . . XP_011 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE :...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.: XP_011 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL ....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...: XP_011 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK ::.:....: ::..:..: .:....: . ::.:...::::.:::.:::: XP_011 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 240 250 260 270 280 >>XP_011534519 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa) initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26 Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285) 10 20 30 40 50 60 pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES ::::: :: ..::.. . . ... .. ...: . . : ..:. .:. XP_011 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE 10 20 30 40 50 70 80 90 100 110 pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS . :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . . XP_011 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE :...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.: XP_011 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL ....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...: XP_011 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK ::.:....: ::..:..: .:....: . ::.:...::::.:::.:::: XP_011 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 240 250 260 270 280 >>XP_016866889 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa) initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26 Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285) 10 20 30 40 50 60 pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES ::::: :: ..::.. . . ... .. ...: . . : ..:. .:. XP_016 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE 10 20 30 40 50 70 80 90 100 110 pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS . :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . . XP_016 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE :...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.: XP_016 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL ....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...: XP_016 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK ::.:....: ::..:..: .:....: . ::.:...::::.:::.:::: XP_016 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 240 250 260 270 280 >>XP_011534516 (OMIM: 603552,605014) PREDICTED: syntaxin (287 aa) initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26 Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285) 10 20 30 40 50 60 pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES ::::: :: ..::.. . . ... .. ...: . . : ..:. .:. XP_011 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE 10 20 30 40 50 70 80 90 100 110 pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS . :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . . XP_011 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE :...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.: XP_011 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL ....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...: XP_011 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK ::.:....: ::..:..: .:....: . ::.:...::::.:::.:::: XP_011 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 240 250 260 270 280 >>NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo sapi (287 aa) initn: 675 init1: 579 opt: 727 Z-score: 588.6 bits: 116.9 E(85289): 4.8e-26 Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:1-285) 10 20 30 40 50 60 pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES ::::: :: ..::.. . . ... .. ...: . . : ..:. .:. NP_003 MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE 10 20 30 40 50 70 80 90 100 110 pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS . :. .:...:.:. ...::::.: .::.. .:.: :: ..: :. .: . . . . NP_003 NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE :...:: :.:.:: ..:. :. ::. : ::.. ....:: : ::::. :::.: NP_003 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL ....::..::::.::.:.::.... ..: :.:::.::.::. ::..:.:...::.:...: NP_003 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK ::.:....: ::..:..: .:....: . ::.:...::::.:::.:::: NP_003 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK 240 250 260 270 280 >>XP_011534515 (OMIM: 603552,605014) PREDICTED: syntaxin (313 aa) initn: 675 init1: 579 opt: 727 Z-score: 588.1 bits: 116.9 E(85289): 5.1e-26 Smith-Waterman score: 727; 37.1% identity (76.3% similar) in 291 aa overlap (1-290:27-311) 10 20 30 pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVF ::::: :: ..::.. . . ... XP_011 MEQPQGDEMDEGEEEEKKARSQPQSKMKDRLAEL------LDLSKQYDQQFPDGDDEFDS 10 20 30 40 50 40 50 60 70 80 90 pF1KB7 LQQAVIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRES-T .. ...: . . : ..:. .:. . :. .:...:.:. ...::::.: .::.. . XP_011 PHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNS 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYND :.: :: ..: :. .: . . . .:...:: :.:.:: ..:. :. ::. : ::. XP_011 IAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQ 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 TIAAKQEKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIE . ....:: : ::::. :::.: ....::..::::.::.:.::.... ..: :.::: XP_011 AEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIE 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 QRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVK .::.::. ::..:.:...::.:...:::.:....: ::..:..: .:....: . ::. XP_011 SRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQ 240 250 260 270 280 290 280 290 pF1KB7 YKKRNPCRVLCCWCCPCCSSK :...::::.:::.:::: XP_011 YEEKNPCRTLCCFCCPCLK 300 310 >>NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Homo s (288 aa) initn: 454 init1: 390 opt: 467 Z-score: 386.2 bits: 79.4 E(85289): 9e-15 Smith-Waterman score: 481; 31.1% identity (67.5% similar) in 283 aa overlap (8-288:1-272) 10 20 30 40 50 60 pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES .:.::.:.. ..:: ... : :: .:. .. ........ NP_004 MKDRTQELRTAKDSD------DDDDV----AVTVDRDRFMDEFFEQVEEIRGF 10 20 30 40 70 80 90 100 110 pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKS :...:.::.. .......:: :.: . ..:: :. . .:... . ... NP_004 IDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQE 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE : : ::. :: :.::... :.: ..: :: : . .:.:: : ::::..:. . NP_004 EGLNR-SSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL :...:::..:. .: ... . .:.: ::::: ::.:...:::.:..:.:.:.....: NP_004 EELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAML 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCCPCCSSK :: ::: :. ::..:. . .::. . ::::. : ... :: NP_004 VESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIAST 230 240 250 260 270 280 NP_004 VGGIFA >>XP_016878382 (OMIM: 601485,616172) PREDICTED: syntaxin (282 aa) initn: 419 init1: 389 opt: 464 Z-score: 384.0 bits: 79.0 E(85289): 1.2e-14 Smith-Waterman score: 464; 30.6% identity (69.4% similar) in 255 aa overlap (36-288:12-265) 10 20 30 40 50 60 pF1KB7 QELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLA ...: .:. .. ........ :..:. XP_016 MEPRAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLS 10 20 30 40 70 80 90 100 110 120 pF1KB7 DNVQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENG ..:.. .:.....:. :.: .: .:: :. . .:. . . ... : : XP_016 EDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNR 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 PSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVND ::. :: :.::... :.: ..: :: : . ...:: : ::::..:. ..:...: XP_016 -SSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELED 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 MLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQG ::..:: .:.... . ..:: :.::: ::.:...::..:..:.:.:.....::: :: XP_016 MLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQG 170 180 190 200 210 220 250 260 270 280 290 pF1KB7 ESINNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCCPCCSSK : :. ::..:. . .::. . ::::. : ... :: XP_016 EMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTL 230 240 250 260 270 280 XP_016 GL >>NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo sapi (288 aa) initn: 453 init1: 389 opt: 464 Z-score: 383.9 bits: 79.0 E(85289): 1.2e-14 Smith-Waterman score: 479; 30.4% identity (67.8% similar) in 283 aa overlap (8-288:1-271) 10 20 30 40 50 60 pF1KB7 MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES .:.::.:.. ..:: . ::. : . .:. .. ........ NP_443 MKDRTQELRSAKDS-----DDEEEVVHV------DRDHFMDEFFEQVEEIRGC 10 20 30 40 70 80 90 100 110 pF1KB7 INNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKS :..:...:.. .:.....:. :.: .: .:: :. . .:. . . ... NP_443 IEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQE 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB7 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE : : ::. :: :.::... :.: ..: :: : . ...:: : ::::..:. .. NP_443 EGLNR-SSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTN 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL :...:::..:: .:.... . ..:: :.::: ::.:...::..:..:.:.:.....: NP_443 EELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAML 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCCPCCSSK :: ::: :. ::..:. . .::. . ::::. : ... :: NP_443 VESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASS 230 240 250 260 270 280 NP_443 IGGTLGL >>NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Homo sa (287 aa) initn: 422 init1: 377 opt: 450 Z-score: 373.0 bits: 77.0 E(85289): 4.9e-14 Smith-Waterman score: 450; 29.5% identity (72.1% similar) in 251 aa overlap (39-288:21-270) 10 20 30 40 50 60 pF1KB7 KQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADNV :. :.. . .:.......::..... : NP_001 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYV 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 QKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSS .. .... .... . .:.: ..:::: :. : .:. . . ..: : .: NP_001 EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNR-TS 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 VVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDMLH : :: ..::... :.: . : ::.. . .:. : : ::::..:. .......::. NP_001 VDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 QGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESI .:: .:. ..... .::. :.:::.:::....::..:..:...:......:: ::: : NP_001 SGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMI 170 180 190 200 210 220 250 260 270 280 290 pF1KB7 NNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK :::: .: .. .::...::. :.::... ... : NP_001 NNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 230 240 250 260 270 280 294 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:55:22 2016 done: Fri Nov 4 04:55:23 2016 Total Scan time: 6.990 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]