FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7121, 305 aa 1>>>pF1KB7121 305 - 305 aa - 305 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9550+/-0.000676; mu= 13.3818+/- 0.041 mean_var=80.0460+/-15.615, 0's: 0 Z-trim(111.6): 7 B-trim: 8 in 1/50 Lambda= 0.143352 statistics sampled from 12484 (12487) to 12484 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.384), width: 16 Scan time: 2.860 The best scores are: opt bits E(32554) CCDS6310.1 TMEM74 gene_id:157753|Hs108|chr8 ( 305) 1998 422.1 2.6e-118 CCDS13011.1 TMEM74B gene_id:55321|Hs108|chr20 ( 256) 498 111.9 5.4e-25 >>CCDS6310.1 TMEM74 gene_id:157753|Hs108|chr8 (305 aa) initn: 1998 init1: 1998 opt: 1998 Z-score: 2237.6 bits: 422.1 E(32554): 2.6e-118 Smith-Waterman score: 1998; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305) 10 20 30 40 50 60 pF1KB7 MELHYLAKKSNQADLCDARDWSSRGLPGDQADTAATRAALCCQKQCASTPRATEMEGSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MELHYLAKKSNQADLCDARDWSSRGLPGDQADTAATRAALCCQKQCASTPRATEMEGSKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SSSPASPSSSLQNSTLQPDAFPPGLLHSGNNQITAERKVCNCCSQELETSFTYVDKNINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SSSPASPSSSLQNSTLQPDAFPPGLLHSGNNQITAERKVCNCCSQELETSFTYVDKNINL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 EQRNRSSPSAKGHNHPGELGWENPNEWSQEAAISLISEEEDDTSSEATSSGKSIDYGFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EQRNRSSPSAKGHNHPGELGWENPNEWSQEAAISLISEEEDDTSSEATSSGKSIDYGFIS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AILFLVTGILLVIISYIVPREVTVDPNTVAAREMERLEKESARLGAHLDRCVIAGLCLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 AILFLVTGILLVIISYIVPREVTVDPNTVAAREMERLEKESARLGAHLDRCVIAGLCLLT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LGGVILSCLLMMSMWKGELYRRNRFASSKESAKLYGSFNFRMKTSTNENTLELSLVEEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LGGVILSCLLMMSMWKGELYRRNRFASSKESAKLYGSFNFRMKTSTNENTLELSLVEEDA 250 260 270 280 290 300 pF1KB7 LAVQS ::::: CCDS63 LAVQS >>CCDS13011.1 TMEM74B gene_id:55321|Hs108|chr20 (256 aa) initn: 543 init1: 473 opt: 498 Z-score: 562.2 bits: 111.9 E(32554): 5.4e-25 Smith-Waterman score: 514; 45.9% identity (65.7% similar) in 242 aa overlap (78-303:24-246) 50 60 70 80 90 pF1KB7 STPRATEMEGSKLSSSPASPSSSLQNSTLQPDAFPPGL-LHSGNNQITAERK-------- : : :::: :.. .: : :. CCDS13 MPPAQGYEFAAAKGPRDELGPSFPMASPPGLELKTLSNGPQAPRRSAPLGPVA 10 20 30 40 50 100 110 120 130 140 150 pF1KB7 -----VCNCC--SQELETSFTYVDKNINLEQRNRSSPSAKGHNHPGELGWENPNEWSQEA : : : :.: :: : .: . . : :::: :: .. : ::. CCDS13 PTREGVENACFSSEEHETHF----QNPG-NTRLGSSPSP-----PGGVS-SLPR--SQRD 60 70 80 90 100 160 170 180 190 200 210 pF1KB7 AISLISEEEDDTSSEATSSGKSIDYGFISAILFLVTGILLVIISYIVPREVTVDPNTVAA .:: ::: . : .: . .::::.::..:::.:::::. .: .:::. :.:.::.: CCDS13 DLSLHSEE--GPALEPVS--RPVDYGFVSALVFLVSGILLVVTAYAIPREARVNPDTVTA 110 120 130 140 150 220 230 240 250 260 270 pF1KB7 REMERLEKESARLGAHLDRCVIAGLCLLTLGGVILSCLLMMSMWKGELYRRNRFASSKES ::::::: ::::.:::::.:::: :::.::..:: :::.:. ::::::: :. .: : CCDS13 REMERLEMYYARLGSHLDRCIIAGLGLLTVGGMLLSVLLMVSLCKGELYRRRTFVPGKGS 160 170 180 190 200 210 280 290 300 pF1KB7 AKLYGSFNFRMKTSTNENTLELSLVEEDALAVQS : :::.:.::. .... .:::.... : CCDS13 RKTYGSINLRMRQLNGDGGQ--ALVENEVVQVSETSHTLQRS 220 230 240 250 305 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 04:57:34 2016 done: Fri Nov 4 04:57:34 2016 Total Scan time: 2.860 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]