FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7139, 333 aa 1>>>pF1KB7139 333 - 333 aa - 333 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7042+/-0.000286; mu= 10.8131+/- 0.018 mean_var=111.1419+/-22.221, 0's: 0 Z-trim(121.4): 47 B-trim: 281 in 1/53 Lambda= 0.121656 statistics sampled from 37853 (37900) to 37853 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.444), width: 16 Scan time: 8.190 The best scores are: opt bits E(85289) NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 2274 409.1 6.5e-114 XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 2274 409.1 6.5e-114 XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 2274 409.1 6.5e-114 NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 995 184.7 2.7e-46 NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 989 183.7 6.3e-46 XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 989 183.7 6.3e-46 NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 935 174.2 3.8e-43 NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 935 174.2 3.8e-43 XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 935 174.2 3.8e-43 XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 935 174.2 3.8e-43 NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 887 165.8 1.8e-40 XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 881 164.7 3.1e-40 XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 881 164.7 3.2e-40 NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 881 164.7 3.2e-40 NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 882 165.0 3.4e-40 NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 487 95.4 1.2e-19 XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 487 95.4 1.2e-19 NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 477 93.7 4.8e-19 NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 477 93.7 4.8e-19 NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 464 91.4 2.3e-18 XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 464 91.4 2.3e-18 NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 464 91.4 2.3e-18 XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 464 91.4 2.3e-18 NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 464 91.4 2.3e-18 XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 464 91.4 2.3e-18 NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 464 91.4 2.3e-18 XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 464 91.4 2.3e-18 NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 449 88.9 2.1e-17 XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 441 87.4 3.8e-17 NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 441 87.4 3.8e-17 NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 439 87.0 5.1e-17 XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 439 87.0 5.1e-17 XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 439 87.0 5.1e-17 NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 439 87.0 5.1e-17 XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 438 87.0 7.5e-17 XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 438 87.0 7.5e-17 NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 438 87.0 7.5e-17 NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 438 87.0 7.5e-17 NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 428 85.1 2.1e-16 XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 425 84.6 2.7e-16 NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 425 84.6 2.7e-16 NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 419 83.5 4.8e-16 XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 419 83.5 4.8e-16 NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 387 77.9 2.9e-14 NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 322 66.5 7.6e-11 XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 293 61.4 2.5e-09 NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 286 60.3 7.6e-09 >>NP_002051 (OMIM: 121012) gap junction alpha-4 protein (333 aa) initn: 2274 init1: 2274 opt: 2274 Z-score: 2166.1 bits: 409.1 E(85289): 6.5e-114 Smith-Waterman score: 2274; 99.7% identity (99.7% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL 250 260 270 280 290 300 310 320 330 pF1KB7 ASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV :::::::::::::::::: :::::::::::::: NP_002 ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV 310 320 330 >>XP_005270807 (OMIM: 121012) PREDICTED: gap junction al (333 aa) initn: 2274 init1: 2274 opt: 2274 Z-score: 2166.1 bits: 409.1 E(85289): 6.5e-114 Smith-Waterman score: 2274; 99.7% identity (99.7% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL 250 260 270 280 290 300 310 320 330 pF1KB7 ASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV :::::::::::::::::: :::::::::::::: XP_005 ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV 310 320 330 >>XP_016856532 (OMIM: 121012) PREDICTED: gap junction al (333 aa) initn: 2274 init1: 2274 opt: 2274 Z-score: 2166.1 bits: 409.1 E(85289): 6.5e-114 Smith-Waterman score: 2274; 99.7% identity (99.7% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERL 250 260 270 280 290 300 310 320 330 pF1KB7 ASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV :::::::::::::::::: :::::::::::::: XP_016 ASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV 310 320 330 >>NP_000156 (OMIM: 104100,121014,133200,164200,186100,21 (382 aa) initn: 1039 init1: 967 opt: 995 Z-score: 952.1 bits: 184.7 E(85289): 2.7e-46 Smith-Waterman score: 1023; 49.1% identity (73.9% similar) in 322 aa overlap (1-298:1-317) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG ::::. : ::::.:: .::. ::.::.::::::::.:: : ::.:::::: :.::: ::: NP_000 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD : :::::..:::::.:.::::..:::.:::.::.::.:. :.::.: .:: ::.. . NP_000 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT .:. : .: . : .. : :....::.:. ::. :.: ::..:..:: :: .::.. NP_000 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM . :..:.: :::. ::::.::::::::::::::::.:.::.::..:: ... . :. NP_000 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK----GV 190 200 210 220 230 250 260 270 pF1KB7 RARQGQDAPPTQGTSS--DPYTD---QVFFYL-----PVGQ-GPSSPP------------ . : . : ..::. .: : : . :. :.. .: ::: NP_000 KDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNS 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 -CPTYNGLSSSEQNWANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV : .:: ..::::::: ..:. NP_000 SCRNYNK-QASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQP 300 310 320 330 340 350 >>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p (435 aa) initn: 1064 init1: 603 opt: 989 Z-score: 945.5 bits: 183.7 E(85289): 6.3e-46 Smith-Waterman score: 1020; 46.8% identity (67.2% similar) in 372 aa overlap (1-328:1-359) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG ::::.:: .::...::::::.::.:::::::::::.:: :.:.::::::::: ::: ::: NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD : :::::.::::::::.:.::..:::::::.:::::... : ::. ...: : . : .. NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEE-EQLKRES 70 80 90 100 110 130 140 150 160 170 pF1KB7 PQVERALAAVERQMAKISVAED-GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGW :. . : . . : .: ::.:. :::. ::: ... :...:.::. ::. :::. NP_068 PSPK------EPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 TMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRG ..:.. :.: ::: ::::.::::::::::::::.:. ::.::.::. :: . :..: NP_068 ELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQG 180 190 200 210 220 230 240 250 260 270 pF1KB7 MRARQGQDA---------PPTQGTSSDPYTDQVFF--YL-----PVGQG-----PSSPP- . .: : :: :: :: : . . : : :.::. :..:: NP_068 VTSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPP 240 250 260 270 280 290 280 290 300 310 pF1KB7 ------------------CPTYNG---LSSSEQNWANLTTEERLASSRPPLFLDPPPQNG ::: : .:::::: ..:.. :: . : . NP_068 AADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-----PPALKAYPAAST 300 310 320 330 340 320 330 pF1KB7 QKSPSRPSSSASKKQYV .:: : .:.: NP_068 PAAPS-PVGSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQP 350 360 370 380 390 400 >>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc (435 aa) initn: 1064 init1: 603 opt: 989 Z-score: 945.5 bits: 183.7 E(85289): 6.3e-46 Smith-Waterman score: 1020; 46.8% identity (67.2% similar) in 372 aa overlap (1-328:1-359) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG ::::.:: .::...::::::.::.:::::::::::.:: :.:.::::::::: ::: ::: XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD : :::::.::::::::.:.::..:::::::.:::::... : ::. ...: : . : .. XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEE-EQLKRES 70 80 90 100 110 130 140 150 160 170 pF1KB7 PQVERALAAVERQMAKISVAED-GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGW :. . : . . : .: ::.:. :::. ::: ... :...:.::. ::. :::. XP_011 PSPK------EPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 TMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRG ..:.. :.: ::: ::::.::::::::::::::.:. ::.::.::. :: . :..: XP_011 ELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQG 180 190 200 210 220 230 240 250 260 270 pF1KB7 MRARQGQDA---------PPTQGTSSDPYTDQVFF--YL-----PVGQG-----PSSPP- . .: : :: :: :: : . . : : :.::. :..:: XP_011 VTSRLGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPP 240 250 260 270 280 290 280 290 300 310 pF1KB7 ------------------CPTYNG---LSSSEQNWANLTTEERLASSRPPLFLDPPPQNG ::: : .:::::: ..:.. :: . : . XP_011 AADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-----PPALKAYPAAST 300 310 320 330 340 320 330 pF1KB7 QKSPSRPSSSASKKQYV .:: : .:.: XP_011 PAAPS-PVGSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQP 350 360 370 380 390 400 >>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc (358 aa) initn: 944 init1: 579 opt: 935 Z-score: 895.6 bits: 174.2 E(85289): 3.8e-43 Smith-Waterman score: 935; 45.8% identity (71.9% similar) in 334 aa overlap (1-324:1-325) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG ::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: ::: NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD : :::::::::::::::::::..:::::.:::.::... : .:. . .:.: :: .. NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG 70 80 90 100 110 130 140 150 160 170 pF1KB7 P-QVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY . : .: . :..: :.: :. ..:.:..::: :.: ....:.::. ::. .: NP_859 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL- : . . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: :: . . NP_859 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN .: .. :: : . :. : : : : : . .::.. ... .:.:: NP_859 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN 240 250 260 270 280 290 300 310 320 330 pF1KB7 WANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV ::.::. .. . : . ::: : :. NP_859 TDNLVTEQVRGQEQTPGEGFIQVRYGQK-PEVPNGVSPGHRLPHGYHSDKRRLSKASSKA 300 310 320 330 340 350 NP_859 RSDDLSV >>NP_005257 (OMIM: 108770,121013,612474,614049) gap junc (358 aa) initn: 944 init1: 579 opt: 935 Z-score: 895.6 bits: 174.2 E(85289): 3.8e-43 Smith-Waterman score: 935; 45.8% identity (71.9% similar) in 334 aa overlap (1-324:1-325) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG ::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: ::: NP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD : :::::::::::::::::::..:::::.:::.::... : .:. . .:.: :: .. NP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG 70 80 90 100 110 130 140 150 160 170 pF1KB7 P-QVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY . : .: . :..: :.: :. ..:.:..::: :.: ....:.::. ::. .: NP_005 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL- : . . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: :: . . NP_005 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN .: .. :: : . :. : : : : : . .::.. ... .:.:: NP_005 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN 240 250 260 270 280 290 300 310 320 330 pF1KB7 WANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV ::.::. .. . : . ::: : :. NP_005 TDNLVTEQVRGQEQTPGEGFIQVRYGQK-PEVPNGVSPGHRLPHGYHSDKRRLSKASSKA 300 310 320 330 340 350 NP_005 RSDDLSV >>XP_016856533 (OMIM: 108770,121013,612474,614049) PREDI (358 aa) initn: 944 init1: 579 opt: 935 Z-score: 895.6 bits: 174.2 E(85289): 3.8e-43 Smith-Waterman score: 935; 45.8% identity (71.9% similar) in 334 aa overlap (1-324:1-325) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG ::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: ::: XP_016 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD : :::::::::::::::::::..:::::.:::.::... : .:. . .:.: :: .. XP_016 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG 70 80 90 100 110 130 140 150 160 170 pF1KB7 P-QVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY . : .: . :..: :.: :. ..:.:..::: :.: ....:.::. ::. .: XP_016 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL- : . . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: :: . . XP_016 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN .: .. :: : . :. : : : : : . .::.. ... .:.:: XP_016 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN 240 250 260 270 280 290 300 310 320 330 pF1KB7 WANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV ::.::. .. . : . ::: : :. XP_016 TDNLVTEQVRGQEQTPGEGFIQVRYGQK-PEVPNGVSPGHRLPHGYHSDKRRLSKASSKA 300 310 320 330 340 350 XP_016 RSDDLSV >>XP_005273008 (OMIM: 108770,121013,612474,614049) PREDI (358 aa) initn: 944 init1: 579 opt: 935 Z-score: 895.6 bits: 174.2 E(85289): 3.8e-43 Smith-Waterman score: 935; 45.8% identity (71.9% similar) in 334 aa overlap (1-324:1-325) 10 20 30 40 50 60 pF1KB7 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG ::::.:: ..:..:..:::::::.:::::::::.:.:: :.:: :::::.::.:.: ::: XP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD : :::::::::::::::::::..:::::.:::.::... : .:. . .:.: :: .. XP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE-RAKEVRG 70 80 90 100 110 130 140 150 160 170 pF1KB7 P-QVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY . : .: . :..: :.: :. ..:.:..::: :.: ....:.::. ::. .: XP_005 SGSYEYPVA----EKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL- : . . ::.:.:::. :.:.:::::::..::.:::.:. .::.:.: :: :: . . XP_005 GIFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 SRGMRARQG----QDAPPTQGT--SSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQN .: .. :: : . :. : : : : : . .::.. ... .:.:: XP_005 QRFVKPRQHMAKCQLSGPSVGIVQSCTPPPD---FNQCLENGPGGKFFNPFSNNMASQQN 240 250 260 270 280 290 300 310 320 330 pF1KB7 WANLTTEERLASSRPPLFLDPPPQNGQKSPSRPSSSASKKQYV ::.::. .. . : . ::: : :. XP_005 TDNLVTEQVRGQEQTPGEGFIQVRYGQK-PEVPNGVSPGHRLPHGYHSDKRRLSKASSKA 300 310 320 330 340 350 XP_005 RSDDLSV 333 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:12:35 2016 done: Fri Nov 4 05:12:36 2016 Total Scan time: 8.190 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]