FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7146, 346 aa 1>>>pF1KB7146 346 - 346 aa - 346 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6431+/-0.000424; mu= 14.9354+/- 0.026 mean_var=80.0982+/-15.622, 0's: 0 Z-trim(111.3): 128 B-trim: 0 in 0/55 Lambda= 0.143306 statistics sampled from 19794 (19922) to 19794 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.234), width: 16 Scan time: 7.820 The best scores are: opt bits E(85289) XP_011543816 (OMIM: 300152) PREDICTED: melanoma-as ( 346) 2234 471.8 9.9e-133 XP_011543815 (OMIM: 300152) PREDICTED: melanoma-as ( 346) 2234 471.8 9.9e-133 NP_002356 (OMIM: 300152) melanoma-associated antig ( 346) 2234 471.8 9.9e-133 NP_002358 (OMIM: 300153) melanoma-associated antig ( 346) 1148 247.2 3.8e-65 NP_796379 (OMIM: 300097) melanoma-associated antig ( 347) 1078 232.8 8.7e-61 NP_803134 (OMIM: 300097) melanoma-associated antig ( 347) 1078 232.8 8.7e-61 NP_002354 (OMIM: 300097) melanoma-associated antig ( 347) 1078 232.8 8.7e-61 NP_872312 (OMIM: 300761) melanoma-associated antig ( 347) 1029 222.6 9.8e-58 XP_011543869 (OMIM: 300763) PREDICTED: melanoma-as ( 336) 1015 219.7 7.1e-57 NP_001264236 (OMIM: 300763) melanoma-associated an ( 336) 1015 219.7 7.1e-57 NP_002355 (OMIM: 300098) melanoma-associated antig ( 319) 996 215.8 1e-55 XP_011543814 (OMIM: 300098) PREDICTED: melanoma-as ( 319) 996 215.8 1e-55 XP_011543755 (OMIM: 300762) PREDICTED: melanoma-as ( 324) 909 197.8 2.7e-50 NP_001093391 (OMIM: 300762) melanoma-associated an ( 324) 909 197.8 2.7e-50 XP_011543756 (OMIM: 300762) PREDICTED: melanoma-as ( 324) 909 197.8 2.7e-50 NP_001258681 (OMIM: 300466) melanoma-associated an ( 275) 877 191.1 2.3e-48 NP_001011543 (OMIM: 300343) melanoma-associated an ( 369) 843 184.2 3.9e-46 NP_066386 (OMIM: 300343) melanoma-associated antig ( 369) 843 184.2 3.9e-46 NP_001238757 (OMIM: 300343) melanoma-associated an ( 369) 843 184.2 3.9e-46 XP_016885011 (OMIM: 300344) PREDICTED: melanoma-as ( 394) 804 176.2 1.1e-43 NP_001011544 (OMIM: 300344) melanoma-associated an ( 400) 804 176.2 1.1e-43 XP_011529466 (OMIM: 300344) PREDICTED: melanoma-as ( 421) 804 176.2 1.2e-43 NP_005357 (OMIM: 300344) melanoma-associated antig ( 429) 804 176.2 1.2e-43 XP_016885010 (OMIM: 300344) PREDICTED: melanoma-as ( 429) 804 176.2 1.2e-43 NP_001011548 (OMIM: 300175) melanoma-associated an ( 317) 788 172.8 9.1e-43 NP_002353 (OMIM: 300175) melanoma-associated antig ( 317) 788 172.8 9.1e-43 XP_005274736 (OMIM: 300175) PREDICTED: melanoma-as ( 317) 788 172.8 9.1e-43 NP_001011549 (OMIM: 300175) melanoma-associated an ( 317) 788 172.8 9.1e-43 NP_001011550 (OMIM: 300175) melanoma-associated an ( 317) 788 172.8 9.1e-43 XP_005274735 (OMIM: 300175) PREDICTED: melanoma-as ( 317) 788 172.8 9.1e-43 XP_005274734 (OMIM: 300175) PREDICTED: melanoma-as ( 397) 788 172.8 1.1e-42 NP_004979 (OMIM: 300016) melanoma-associated antig ( 309) 780 171.1 2.8e-42 NP_001159872 (OMIM: 300341) melanoma-associated an ( 318) 766 168.2 2.1e-41 NP_005355 (OMIM: 300341) melanoma-associated antig ( 318) 766 168.2 2.1e-41 NP_001159873 (OMIM: 300341) melanoma-associated an ( 318) 766 168.2 2.1e-41 XP_016885009 (OMIM: 300341) PREDICTED: melanoma-as ( 318) 766 168.2 2.1e-41 NP_775794 (OMIM: 300467) melanoma-associated antig ( 407) 762 167.5 4.6e-41 NP_057333 (OMIM: 300468) melanoma-associated antig ( 373) 722 159.2 1.3e-38 XP_005278249 (OMIM: 300764) PREDICTED: melanoma-as ( 315) 720 158.7 1.5e-38 XP_005262392 (OMIM: 300342) PREDICTED: melanoma-as ( 315) 720 158.7 1.5e-38 NP_001074259 (OMIM: 300764) melanoma-associated an ( 315) 720 158.7 1.5e-38 NP_005356 (OMIM: 300342) melanoma-associated antig ( 315) 720 158.7 1.5e-38 XP_005262391 (OMIM: 300342) PREDICTED: melanoma-as ( 315) 720 158.7 1.5e-38 XP_005278250 (OMIM: 300764) PREDICTED: melanoma-as ( 315) 720 158.7 1.5e-38 NP_001308331 (OMIM: 300549) melanoma-associated an ( 314) 689 152.3 1.3e-36 NP_705692 (OMIM: 300549) melanoma-associated antig ( 314) 689 152.3 1.3e-36 NP_786884 (OMIM: 300173) melanoma-associated antig ( 314) 689 152.3 1.3e-36 NP_001308332 (OMIM: 300549) melanoma-associated an ( 314) 689 152.3 1.3e-36 NP_005352 (OMIM: 300173) melanoma-associated antig ( 314) 689 152.3 1.3e-36 NP_001269430 (OMIM: 300173) melanoma-associated an ( 314) 689 152.3 1.3e-36 >>XP_011543816 (OMIM: 300152) PREDICTED: melanoma-associ (346 aa) initn: 2234 init1: 2234 opt: 2234 Z-score: 2503.9 bits: 471.8 E(85289): 9.9e-133 Smith-Waterman score: 2234; 99.4% identity (99.7% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ALKKPQRALSTTTSVDVSYKKSYKGANSKIEKKQSFSQGLSSTVQSHTDPLTMKTNMLVQ ::::::::::::::::::::::::::::::::::::::::::::::.:::: :::::::: XP_011 ALKKPQRALSTTTSVDVSYKKSYKGANSKIEKKQSFSQGLSSTVQSRTDPLIMKTNMLVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTVP 250 260 270 280 290 300 310 320 330 340 pF1KB7 SAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA 310 320 330 340 >>XP_011543815 (OMIM: 300152) PREDICTED: melanoma-associ (346 aa) initn: 2234 init1: 2234 opt: 2234 Z-score: 2503.9 bits: 471.8 E(85289): 9.9e-133 Smith-Waterman score: 2234; 99.4% identity (99.7% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ALKKPQRALSTTTSVDVSYKKSYKGANSKIEKKQSFSQGLSSTVQSHTDPLTMKTNMLVQ ::::::::::::::::::::::::::::::::::::::::::::::.:::: :::::::: XP_011 ALKKPQRALSTTTSVDVSYKKSYKGANSKIEKKQSFSQGLSSTVQSRTDPLIMKTNMLVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTVP 250 260 270 280 290 300 310 320 330 340 pF1KB7 SAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA 310 320 330 340 >>NP_002356 (OMIM: 300152) melanoma-associated antigen B (346 aa) initn: 2234 init1: 2234 opt: 2234 Z-score: 2503.9 bits: 471.8 E(85289): 9.9e-133 Smith-Waterman score: 2234; 99.4% identity (99.7% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ALKKPQRALSTTTSVDVSYKKSYKGANSKIEKKQSFSQGLSSTVQSHTDPLTMKTNMLVQ ::::::::::::::::::::::::::::::::::::::::::::::.:::: :::::::: NP_002 ALKKPQRALSTTTSVDVSYKKSYKGANSKIEKKQSFSQGLSSTVQSRTDPLIMKTNMLVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHFI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 FGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTVP 250 260 270 280 290 300 310 320 330 340 pF1KB7 SAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA :::::::::::::::::::::::::::::::::::::::::::::: NP_002 SAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA 310 320 330 340 >>NP_002358 (OMIM: 300153) melanoma-associated antigen B (346 aa) initn: 1114 init1: 662 opt: 1148 Z-score: 1290.5 bits: 247.2 E(85289): 3.8e-65 Smith-Waterman score: 1148; 55.7% identity (76.7% similar) in 348 aa overlap (1-345:1-344) 10 20 30 40 50 60 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS ::::::: :.::::::.::::::: . .: ::..:.. :: .: : :.. . . NP_002 MPRGQKSKLRAREKRQRTRGQTQDLKVGQPTAAEKEESPSSSSSVLRDTA---SSSLAFG 10 20 30 40 50 70 80 90 100 110 pF1KB7 ALKKPQRALSTTTSVD-VSYKKSYKGANSKIEKKQSFSQGLSSTVQSHTDPLTMKTNMLV ..::: ::... .: : :: .:. :.. : ::. .:: .: : :: ::.::: NP_002 IPQEPQREPPTTSAAAAMSCTGSDKGDESQDEENASSSQASTSTERSLKDSLTRKTKMLV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 QFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYV :::. ::::.: ::.::::..:..:. ::::..:.: :.:::. ::.:. : ::. NP_002 QFLLYKYKMKEPTTKAEMLKIISKKYKEHFPEIFRKVSQRTELVFGLALKEVNPTTHSYI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHF ::: . ::.:. . . .:..:::. ::.:::..:::: ::.:::::: . :::::.:. NP_002 LVSMLG-PNDGNQSSAWTLPRNGLLMPLLSVIFLNGNCAREEEIWEFLNMLGIYDGKRHL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 IFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTV ::::::::::::::. :::::.:::::.: ::.::::::::::::::::::: :::: :. NP_002 IFGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDTT 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 PSAFQFWYEEALRDEEERVQAAAMLND--GSSAMGRKCSKAKASSSSHA :. : . :::::::::::. : . :..:: :.: .::::. NP_002 PNNFPLLYEEALRDEEERAGARPRVAARRGTTAMTSAYSRATSSSSSQPM 300 310 320 330 340 >>NP_796379 (OMIM: 300097) melanoma-associated antigen B (347 aa) initn: 1112 init1: 928 opt: 1078 Z-score: 1212.3 bits: 232.8 E(85289): 8.7e-61 Smith-Waterman score: 1078; 51.0% identity (77.4% similar) in 349 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS ::::::: :.:::::...: .:: . :. ::..:.. ::: .:: : .. :. . NP_796 MPRGQKSKLRAREKRRKAREETQGLKVAHATAAEKEECPSSSP-VLGDTPTSSPAA---G 10 20 30 40 50 70 80 90 100 110 pF1KB7 ALKKPQRALSTTTSVD-VSYKKSYKGANSKIEKKQSFSQGLSSTVQSHTDPLTMKTNMLV .::: : :::.. :: .: .::. . :.. ::::. .:: .: ::.. ...::. NP_796 IPQKPQGAPPTTTAAAAVSCTESDEGAKCQGEENASFSQATTSTESSVKDPVAWEAGMLM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 QFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYV .:... :::..:::::::::.:....:. : :::. :: .:.:::.:::. . . .:. NP_796 HFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGASRRLELVFGLDLKEDNPSGHTYT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHF ::::..: :.:... ::..:::. ::::::.::: ::::.::.:.: . :::..:. NP_796 LVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLKGNSATEEEIWKFMNVLGAYDGEEHL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 IFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTV :.:::::.::::::. :::.:.:::::.: ::.:::::::.:::.::::::: ::.: .. NP_796 IYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFLWGPRAYAETTKMKVLEFLAKMNGAT 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 PSAFQFWYEEALRDEEERVQAAAMLND---GSSAMGRKCSKAKASSSSHA : : :::::::::::.:. . . ... : :.: : ::: NP_796 PRDFPSHYEEALRDEEERAQVRSSVRARRRTTATTFRARSRAPFSRSSHPM 300 310 320 330 340 >>NP_803134 (OMIM: 300097) melanoma-associated antigen B (347 aa) initn: 1112 init1: 928 opt: 1078 Z-score: 1212.3 bits: 232.8 E(85289): 8.7e-61 Smith-Waterman score: 1078; 51.0% identity (77.4% similar) in 349 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS ::::::: :.:::::...: .:: . :. ::..:.. ::: .:: : .. :. . NP_803 MPRGQKSKLRAREKRRKAREETQGLKVAHATAAEKEECPSSSP-VLGDTPTSSPAA---G 10 20 30 40 50 70 80 90 100 110 pF1KB7 ALKKPQRALSTTTSVD-VSYKKSYKGANSKIEKKQSFSQGLSSTVQSHTDPLTMKTNMLV .::: : :::.. :: .: .::. . :.. ::::. .:: .: ::.. ...::. NP_803 IPQKPQGAPPTTTAAAAVSCTESDEGAKCQGEENASFSQATTSTESSVKDPVAWEAGMLM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 QFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYV .:... :::..:::::::::.:....:. : :::. :: .:.:::.:::. . . .:. NP_803 HFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGASRRLELVFGLDLKEDNPSGHTYT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHF ::::..: :.:... ::..:::. ::::::.::: ::::.::.:.: . :::..:. NP_803 LVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLKGNSATEEEIWKFMNVLGAYDGEEHL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 IFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTV :.:::::.::::::. :::.:.:::::.: ::.:::::::.:::.::::::: ::.: .. NP_803 IYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFLWGPRAYAETTKMKVLEFLAKMNGAT 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 PSAFQFWYEEALRDEEERVQAAAMLND---GSSAMGRKCSKAKASSSSHA : : :::::::::::.:. . . ... : :.: : ::: NP_803 PRDFPSHYEEALRDEEERAQVRSSVRARRRTTATTFRARSRAPFSRSSHPM 300 310 320 330 340 >>NP_002354 (OMIM: 300097) melanoma-associated antigen B (347 aa) initn: 1112 init1: 928 opt: 1078 Z-score: 1212.3 bits: 232.8 E(85289): 8.7e-61 Smith-Waterman score: 1078; 51.0% identity (77.4% similar) in 349 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS ::::::: :.:::::...: .:: . :. ::..:.. ::: .:: : .. :. . NP_002 MPRGQKSKLRAREKRRKAREETQGLKVAHATAAEKEECPSSSP-VLGDTPTSSPAA---G 10 20 30 40 50 70 80 90 100 110 pF1KB7 ALKKPQRALSTTTSVD-VSYKKSYKGANSKIEKKQSFSQGLSSTVQSHTDPLTMKTNMLV .::: : :::.. :: .: .::. . :.. ::::. .:: .: ::.. ...::. NP_002 IPQKPQGAPPTTTAAAAVSCTESDEGAKCQGEENASFSQATTSTESSVKDPVAWEAGMLM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 QFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSYV .:... :::..:::::::::.:....:. : :::. :: .:.:::.:::. . . .:. NP_002 HFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGASRRLELVFGLDLKEDNPSGHTYT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKHF ::::..: :.:... ::..:::. ::::::.::: ::::.::.:.: . :::..:. NP_002 LVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLKGNSATEEEIWKFMNVLGAYDGEEHL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 IFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKTV :.:::::.::::::. :::.:.:::::.: ::.:::::::.:::.::::::: ::.: .. NP_002 IYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFLWGPRAYAETTKMKVLEFLAKMNGAT 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 PSAFQFWYEEALRDEEERVQAAAMLND---GSSAMGRKCSKAKASSSSHA : : :::::::::::.:. . . ... : :.: : ::: NP_002 PRDFPSHYEEALRDEEERAQVRSSVRARRRTTATTFRARSRAPFSRSSHPM 300 310 320 330 340 >>NP_872312 (OMIM: 300761) melanoma-associated antigen B (347 aa) initn: 1049 init1: 1027 opt: 1029 Z-score: 1157.5 bits: 222.6 E(85289): 9.8e-58 Smith-Waterman score: 1029; 47.6% identity (74.6% similar) in 347 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKVSFSSPLILGATIQKKSAGRSRS ::::::: :.:::::.:.:: .: : .... :. : ..:.. : : . NP_872 MPRGQKSKLRAREKRRQARGGLEDLIDALDILEEEEESPPSASACLKDVFQSSLDGASNN 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 --ALKKPQRALSTTTSVDVSYKKSYKGANSKIEKKQSFSQGLSSTVQSHTDPLTMKTNML .:.. : ..:... .:. . .:.:...:.. .: : .: . :. :. .: NP_872 PHGLREAQS--TSTSATAASHTRHPEGVNDQMEERPICTQDLEATDSFPRGPVDEKVIIL 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDSY :..:. :.::.:: :::::. : . :. :: ::..:: ..:..::.:::.:. .: : NP_872 VHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLKEVEPNKHIY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 VLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKKH :::.:.:: .. .. : ::::::...::.:: .:::..::..:. .: : .::: .: NP_872 VLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNTMGLYDGIEH 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 FIFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNKT :.:::::::.:.:::: .::::.:::::.: ::.::::::::::::::::::: :::: : NP_872 FMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDT 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 VPSAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA .:: :. :: :::.:::::..: . . :: . ::.:.:.::. NP_872 APSEFSNWYTEALQDEEERARARVAAKARVSATAGARSKVKSSKSSQLQ 300 310 320 330 340 >>XP_011543869 (OMIM: 300763) PREDICTED: melanoma-associ (336 aa) initn: 1010 init1: 883 opt: 1015 Z-score: 1142.1 bits: 219.7 E(85289): 7.1e-57 Smith-Waterman score: 1015; 50.8% identity (77.2% similar) in 333 aa overlap (1-330:1-328) 10 20 30 40 50 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKV-SFSSPLILGATIQKKSAGRSR ::::: : .:::::.:.::. : ::: ::..:.:. : ::: . . .:: XP_011 MPRGQASKRRAREKRRQARGEDQCLGGAQATAAEKEKLPSSSSPACQSPPQSFPNAG--- 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 SALKKPQRA-LSTTTSVDVSYKKSYKGANS-KIEKKQSFSQGLSSTVQSHTDPLTMKTNM .. ::: .. . :: .: .::.. : :. .:: .: ::. .. : :. ::. XP_011 -IPQESQRASYPSSPASAVSLTSSDEGAKGQKGESPNSF-HGPSSSESTGRDLLNTKTGE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 LVQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDS :::::.. : :.:: . :::......:. :::::.... :.:::::. ::..: ...: XP_011 LVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYLKEMDPSRQS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 YVLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKK ::::.:.:.::.:... : ::: .:::. ::..:::.:: ::::..:: :: . .: :.: XP_011 YVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLNALGMYKGRK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 HFIFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNK :::.:::..:.:.:::. ::::.:::.:.: ::::::::::.::::::::::: ::.: XP_011 HFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMKVLEFVAKLND 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 TVPSAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA :: :... ::::::.:::...: :. :.. : XP_011 TVASTYKSRYEEALREEEEQARARAVARDSARARASRSFQP 300 310 320 330 >>NP_001264236 (OMIM: 300763) melanoma-associated antige (336 aa) initn: 1010 init1: 883 opt: 1015 Z-score: 1142.1 bits: 219.7 E(85289): 7.1e-57 Smith-Waterman score: 1015; 50.8% identity (77.2% similar) in 333 aa overlap (1-330:1-328) 10 20 30 40 50 pF1KB7 MPRGQKSTLHAREKRQQTRGQTQDHQGAQITATNKKKV-SFSSPLILGATIQKKSAGRSR ::::: : .:::::.:.::. : ::: ::..:.:. : ::: . . .:: NP_001 MPRGQASKRRAREKRRQARGEDQCLGGAQATAAEKEKLPSSSSPACQSPPQSFPNAG--- 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 SALKKPQRA-LSTTTSVDVSYKKSYKGANS-KIEKKQSFSQGLSSTVQSHTDPLTMKTNM .. ::: .. . :: .: .::.. : :. .:: .: ::. .. : :. ::. NP_001 -IPQESQRASYPSSPASAVSLTSSDEGAKGQKGESPNSF-HGPSSSESTGRDLLNTKTGE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 LVQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDSTKDS :::::.. : :.:: . :::......:. :::::.... :.:::::. ::..: ...: NP_001 LVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYLKEMDPSRQS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 YVLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIYDGKK ::::.:.:.::.:... : ::: .:::. ::..:::.:: ::::..:: :: . .: :.: NP_001 YVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLNALGMYKGRK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 HFIFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWAKVNK :::.:::..:.:.:::. ::::.:::.:.: ::::::::::.::::::::::: ::.: NP_001 HFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMKVLEFVAKLND 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 TVPSAFQFWYEEALRDEEERVQAAAMLNDGSSAMGRKCSKAKASSSSHA :: :... ::::::.:::...: :. :.. : NP_001 TVASTYKSRYEEALREEEEQARARAVARDSARARASRSFQP 300 310 320 330 346 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:16:28 2016 done: Fri Nov 4 05:16:29 2016 Total Scan time: 7.820 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]