FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7156, 359 aa 1>>>pF1KB7156 359 - 359 aa - 359 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8252+/-0.000486; mu= 13.2816+/- 0.030 mean_var=103.3362+/-26.567, 0's: 0 Z-trim(109.9): 737 B-trim: 1744 in 2/47 Lambda= 0.126168 statistics sampled from 17324 (18160) to 17324 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.562), E-opt: 0.2 (0.213), width: 16 Scan time: 7.740 The best scores are: opt bits E(85289) NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 2369 442.6 6.4e-124 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 2369 442.6 6.4e-124 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 2369 442.6 6.8e-124 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 2369 442.6 6.9e-124 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 2369 442.6 6.9e-124 XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 759 149.5 1.1e-35 NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 759 149.5 1.1e-35 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 689 136.8 7.2e-32 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 689 136.8 7.2e-32 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 689 136.8 7.4e-32 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 689 136.8 7.4e-32 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 658 131.2 3.6e-30 NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 652 130.1 8.1e-30 NP_000701 (OMIM: 600337) B1 bradykinin receptor [H ( 353) 645 128.8 1.8e-29 NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 632 126.4 9.9e-29 NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 632 126.4 9.9e-29 NP_064707 (OMIM: 610376) atypical chemokine recept ( 362) 624 125.0 2.7e-28 XP_005246155 (OMIM: 610376) PREDICTED: atypical ch ( 362) 624 125.0 2.7e-28 XP_016860005 (OMIM: 610376) PREDICTED: atypical ch ( 362) 624 125.0 2.7e-28 XP_005246154 (OMIM: 610376) PREDICTED: atypical ch ( 362) 624 125.0 2.7e-28 NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 614 123.2 9.5e-28 XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 614 123.2 9.7e-28 NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 614 123.2 1e-27 XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 614 123.2 1e-27 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 612 122.8 1.2e-27 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 612 122.8 1.2e-27 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 611 122.6 1.4e-27 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 611 122.6 1.4e-27 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 611 122.6 1.4e-27 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 611 122.6 1.4e-27 NP_001248381 (OMIM: 600239) G-protein coupled rece ( 355) 609 122.2 1.7e-27 NP_001248384 (OMIM: 600239) G-protein coupled rece ( 355) 609 122.2 1.7e-27 XP_005246528 (OMIM: 600239) PREDICTED: G-protein c ( 355) 609 122.2 1.7e-27 NP_005270 (OMIM: 600239) G-protein coupled recepto ( 355) 609 122.2 1.7e-27 NP_001248383 (OMIM: 600239) G-protein coupled rece ( 355) 609 122.2 1.7e-27 XP_016859321 (OMIM: 600239) PREDICTED: G-protein c ( 355) 609 122.2 1.7e-27 NP_001248382 (OMIM: 600239) G-protein coupled rece ( 355) 609 122.2 1.7e-27 NP_001091669 (OMIM: 600239) G-protein coupled rece ( 355) 609 122.2 1.7e-27 NP_000614 (OMIM: 113503) B2 bradykinin receptor [H ( 391) 605 121.5 3.1e-27 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 597 120.1 8.4e-27 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 596 119.9 9e-27 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 592 119.1 1.5e-26 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 592 119.1 1.5e-26 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 592 119.1 1.5e-26 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 592 119.1 1.5e-26 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 592 119.1 1.5e-26 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 592 119.1 1.5e-26 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 592 119.2 1.5e-26 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 592 119.2 1.6e-26 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 592 119.2 1.7e-26 >>NP_000676 (OMIM: 106165,145500,267430) type-1 angioten (359 aa) initn: 2369 init1: 2369 opt: 2369 Z-score: 2345.7 bits: 442.6 E(85289): 6.4e-124 Smith-Waterman score: 2369; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB7 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE 310 320 330 340 350 >>NP_033611 (OMIM: 106165,145500,267430) type-1 angioten (359 aa) initn: 2369 init1: 2369 opt: 2369 Z-score: 2345.7 bits: 442.6 E(85289): 6.4e-124 Smith-Waterman score: 2369; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB7 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_033 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_033 TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_033 CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_033 AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_033 IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_033 FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE 310 320 330 340 350 >>NP_114438 (OMIM: 106165,145500,267430) type-1 angioten (388 aa) initn: 2369 init1: 2369 opt: 2369 Z-score: 2345.3 bits: 442.6 E(85289): 6.8e-124 Smith-Waterman score: 2369; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:30-388) 10 20 30 pF1KB7 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMI ::::::::::::::::::::::::::::::: NP_114 MLTFTSECGCTTFGVFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVMI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 PTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAME 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 YRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 YRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCII 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 IWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 IWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLII 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 LTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 LTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGII 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 RDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 RDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLS 310 320 330 340 350 360 340 350 pF1KB7 TKMSTLSYRPSDNVSSSTKKPAPCFEVE :::::::::::::::::::::::::::: NP_114 TKMSTLSYRPSDNVSSSTKKPAPCFEVE 370 380 >>NP_114038 (OMIM: 106165,145500,267430) type-1 angioten (394 aa) initn: 2369 init1: 2369 opt: 2369 Z-score: 2345.2 bits: 442.6 E(85289): 6.9e-124 Smith-Waterman score: 2369; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:36-394) 10 20 30 pF1KB7 MILNSSTEDGIKRIQDDCPKAGRHNYIFVM :::::::::::::::::::::::::::::: NP_114 HKSTDSPKAPQLRGGVFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVM 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 ILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 ILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 IRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 IRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNL 310 320 330 340 350 360 340 350 pF1KB7 STKMSTLSYRPSDNVSSSTKKPAPCFEVE ::::::::::::::::::::::::::::: NP_114 STKMSTLSYRPSDNVSSSTKKPAPCFEVE 370 380 390 >>NP_004826 (OMIM: 106165,145500,267430) type-1 angioten (394 aa) initn: 2369 init1: 2369 opt: 2369 Z-score: 2345.2 bits: 442.6 E(85289): 6.9e-124 Smith-Waterman score: 2369; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:36-394) 10 20 30 pF1KB7 MILNSSTEDGIKRIQDDCPKAGRHNYIFVM :::::::::::::::::::::::::::::: NP_004 HKSTDSPKAPQLRGGVFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVM 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 ILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGI 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 IRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNL 310 320 330 340 350 360 340 350 pF1KB7 STKMSTLSYRPSDNVSSSTKKPAPCFEVE ::::::::::::::::::::::::::::: NP_004 STKMSTLSYRPSDNVSSSTKKPAPCFEVE 370 380 390 >>XP_011535835 (OMIM: 300034) PREDICTED: type-2 angioten (363 aa) initn: 723 init1: 627 opt: 759 Z-score: 761.9 bits: 149.5 E(85289): 1.1e-35 Smith-Waterman score: 759; 36.5% identity (72.1% similar) in 312 aa overlap (31-337:47-355) 10 20 30 40 50 pF1KB7 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL- :: :: ::::.:.. : .::.... .: XP_011 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB7 KTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL : :.:....:::.::: .: ::::::.: ...: : :: .::. .. ...:..::.:.. XP_011 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB7 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV ::.:.::: ....:. :. ::. :. ..: .: :.:::.. :.: :: .... XP_011 TCMSVDRYQSVIYPFLSQ-RRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB7 CAFHYESQN-STLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDI : . . .. . :..: ::::::..:...: : : : : : :. ::. :.. XP_011 CIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQV 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB7 FKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLN .:. :.:: :.. :.: ...::::.: .:.: .:.. ..: :.:..: ... :.:.: XP_011 LKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVN 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB7 PLFYGFLGKKFKRYFLQLLKYIPP---KAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPC :..: :.:..:.. . .... .: ..: .: : :.: XP_011 PFLYCFVGNRFQQKLRSVFR-VPITWLQGKRESMSCRKSSSLREMETFVS 320 330 340 350 360 pF1KB7 FEVE >>NP_000677 (OMIM: 300034) type-2 angiotensin II recepto (363 aa) initn: 723 init1: 627 opt: 759 Z-score: 761.9 bits: 149.5 E(85289): 1.1e-35 Smith-Waterman score: 759; 36.5% identity (72.1% similar) in 312 aa overlap (31-337:47-355) 10 20 30 40 50 pF1KB7 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL- :: :: ::::.:.. : .::.... .: NP_000 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB7 KTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL : :.:....:::.::: .: ::::::.: ...: : :: .::. .. ...:..::.:.. NP_000 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB7 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV ::.:.::: ....:. :. ::. :. ..: .: :.:::.. :.: :: .... NP_000 TCMSVDRYQSVIYPFLSQ-RRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB7 CAFHYESQN-STLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDI : . . .. . :..: ::::::..:...: : : : : : :. ::. :.. NP_000 CIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQV 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB7 FKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLN .:. :.:: :.. :.: ...::::.: .:.: .:.. ..: :.:..: ... :.:.: NP_000 LKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVN 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB7 PLFYGFLGKKFKRYFLQLLKYIPP---KAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPC :..: :.:..:.. . .... .: ..: .: : :.: NP_000 PFLYCFVGNRFQQKLRSVFR-VPITWLQGKRESMSCRKSSSLREMETFVS 320 330 340 350 360 pF1KB7 FEVE >>NP_006632 (OMIM: 604738) C-C chemokine receptor type 9 (357 aa) initn: 467 init1: 264 opt: 689 Z-score: 693.1 bits: 136.8 E(85289): 7.2e-32 Smith-Waterman score: 689; 33.8% identity (70.6% similar) in 320 aa overlap (5-318:11-321) 10 20 30 40 50 pF1KB7 MILNSSTEDGIKRIQDD--CPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIV :: :: .. : : : . ... ..: :: ..:.:: .:::::..: NP_006 MADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 IYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNL .. ..::....::::::.::: ::.:::.::. .: . : : ...::.... ..:. NP_006 YWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQ--WKFQTFMCKVVNSMYKMNF 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YASVFLLTCLSIDRYLAIVHPMKSRLRRT--MLVAKVTCIIIWLLAGLASLPAIIHRNVF :. :.:. :.:.:::.::.. :... : .: .:..:. ::.::. .: :.. .. NP_006 YSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQI- 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 FIENTNITVCAFHYESQNST-LPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQ :...:..:.. : :..:: : .. : ::::..::... ::.: ..: :: NP_006 -KEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTL-----IQ 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 KNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGI-IRDCRIADIVDTAMPITI .: . .:. .... : .: .:.. . ..... .. : .: .. .: . .: NP_006 AKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQ 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 CIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSS ::.:..::::..: :.:..:.: ... :: NP_006 TIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETT 300 310 320 330 340 350 >>NP_001243298 (OMIM: 604738) C-C chemokine receptor typ (357 aa) initn: 467 init1: 264 opt: 689 Z-score: 693.1 bits: 136.8 E(85289): 7.2e-32 Smith-Waterman score: 689; 33.8% identity (70.6% similar) in 320 aa overlap (5-318:11-321) 10 20 30 40 50 pF1KB7 MILNSSTEDGIKRIQDD--CPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIV :: :: .. : : : . ... ..: :: ..:.:: .:::::..: NP_001 MADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 IYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNL .. ..::....::::::.::: ::.:::.::. .: . : : ...::.... ..:. NP_001 YWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQ--WKFQTFMCKVVNSMYKMNF 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 YASVFLLTCLSIDRYLAIVHPMKSRLRRT--MLVAKVTCIIIWLLAGLASLPAIIHRNVF :. :.:. :.:.:::.::.. :... : .: .:..:. ::.::. .: :.. .. NP_001 YSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQI- 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 FIENTNITVCAFHYESQNST-LPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQ :...:..:.. : :..:: : .. : ::::..::... ::.: ..: :: NP_001 -KEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTL-----IQ 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 KNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGI-IRDCRIADIVDTAMPITI .: . .:. .... : .: .:.. . ..... .. : .: .. .: . .: NP_001 AKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQ 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 CIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSS ::.:..::::..: :.:..:.: ... :: NP_001 TIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETT 300 310 320 330 340 350 >>XP_011531614 (OMIM: 604738) PREDICTED: C-C chemokine r (369 aa) initn: 467 init1: 264 opt: 689 Z-score: 692.9 bits: 136.8 E(85289): 7.4e-32 Smith-Waterman score: 689; 33.8% identity (70.6% similar) in 320 aa overlap (5-318:23-333) 10 20 30 40 pF1KB7 MILNSSTEDGIKRIQDD--CPKAGRHNYIFVMIPTLYSIIFV :: :: .. : : : . ... ..: :: ..:. XP_011 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 VGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYL :: .:::::..: .. ..::....::::::.::: ::.:::.::. .: . : : ... XP_011 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQ--WKFQTFM 70 80 90 100 110 110 120 130 140 150 pF1KB7 CKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRT--MLVAKVTCIIIWLLAGL ::.... ..:.:. :.:. :.:.:::.::.. :... : .: .:..:. ::.::. XP_011 CKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAA 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 ASLPAIIHRNVFFIENTNITVCAFHYESQNST-LPIGLGLTKNILGFLFPFLIILTSYTL .: :.. .. :...:..:.. : :..:: : .. : ::::..::... ::. XP_011 LCIPEILYSQI--KEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTI 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 IWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGI-IRDCRI : ..: :: .: . .:. .... : .: .:.. . ..... .. : .: . XP_011 IIHTL-----IQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAV 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 ADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMST . .: . .: ::.:..::::..: :.:..:.: ... :: XP_011 STNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREG 300 310 320 330 340 350 340 350 pF1KB7 LSYRPSDNVSSSTKKPAPCFEVE XP_011 SLKLSSMLLETTSGALSL 360 359 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:20:54 2016 done: Fri Nov 4 05:20:56 2016 Total Scan time: 7.740 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]