FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7157, 360 aa 1>>>pF1KB7157 360 - 360 aa - 360 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5783+/-0.000391; mu= 21.4091+/- 0.024 mean_var=106.5881+/-27.575, 0's: 0 Z-trim(112.6): 404 B-trim: 1300 in 1/51 Lambda= 0.124228 statistics sampled from 21000 (21559) to 21000 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.253), width: 16 Scan time: 7.330 The best scores are: opt bits E(85289) XP_016855750 (OMIM: 605051) PREDICTED: cannabinoid ( 360) 2411 443.2 4.1e-124 NP_001832 (OMIM: 605051) cannabinoid receptor 2 [H ( 360) 2411 443.2 4.1e-124 XP_011538931 (OMIM: 605051) PREDICTED: cannabinoid ( 360) 2411 443.2 4.1e-124 NP_149421 (OMIM: 114610) cannabinoid receptor 1 is ( 439) 666 130.6 6.4e-30 XP_011533727 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 666 130.7 6.7e-30 XP_011533728 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 666 130.7 6.7e-30 XP_011533730 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 666 130.7 6.7e-30 XP_016865727 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 666 130.7 6.7e-30 XP_006715393 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 666 130.7 6.7e-30 XP_011533726 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 666 130.7 6.7e-30 NP_001153698 (OMIM: 114610) cannabinoid receptor 1 ( 472) 666 130.7 6.7e-30 XP_016865728 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 666 130.7 6.7e-30 NP_001153730 (OMIM: 114610) cannabinoid receptor 1 ( 472) 666 130.7 6.7e-30 NP_001153731 (OMIM: 114610) cannabinoid receptor 1 ( 472) 666 130.7 6.7e-30 NP_057167 (OMIM: 114610) cannabinoid receptor 1 is ( 472) 666 130.7 6.7e-30 XP_016865729 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 666 130.7 6.7e-30 NP_005279 (OMIM: 600752) G-protein coupled recepto ( 334) 412 84.9 2.8e-16 NP_001159687 (OMIM: 605146) sphingosine 1-phosphat ( 398) 385 80.2 8.8e-15 NP_110387 (OMIM: 605146) sphingosine 1-phosphate r ( 398) 385 80.2 8.8e-15 NP_005275 (OMIM: 600553) G-protein coupled recepto ( 362) 382 79.6 1.2e-14 NP_001273028 (OMIM: 600553) G-protein coupled rece ( 377) 382 79.6 1.2e-14 NP_005272 (OMIM: 600241) G-protein coupled recepto ( 330) 381 79.4 1.3e-14 NP_003766 (OMIM: 603751) sphingosine 1-phosphate r ( 384) 374 78.2 3.4e-14 XP_016869895 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869874 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869876 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_005251839 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869891 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869890 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869875 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869883 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869881 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869873 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869878 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869877 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 NP_001392 (OMIM: 602282) lysophosphatidic acid rec ( 364) 373 78.0 3.7e-14 XP_016869889 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869872 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869894 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869896 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869893 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 NP_476500 (OMIM: 602282) lysophosphatidic acid rec ( 364) 373 78.0 3.7e-14 XP_016869882 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869885 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869888 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869879 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_005251838 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869884 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869892 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 XP_016869887 (OMIM: 602282) PREDICTED: lysophospha ( 364) 373 78.0 3.7e-14 >>XP_016855750 (OMIM: 605051) PREDICTED: cannabinoid rec (360 aa) initn: 2411 init1: 2411 opt: 2411 Z-score: 2349.2 bits: 443.2 E(85289): 4.1e-124 Smith-Waterman score: 2411; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC 310 320 330 340 350 360 >>NP_001832 (OMIM: 605051) cannabinoid receptor 2 [Homo (360 aa) initn: 2411 init1: 2411 opt: 2411 Z-score: 2349.2 bits: 443.2 E(85289): 4.1e-124 Smith-Waterman score: 2411; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC 310 320 330 340 350 360 >>XP_011538931 (OMIM: 605051) PREDICTED: cannabinoid rec (360 aa) initn: 2411 init1: 2411 opt: 2411 Z-score: 2349.2 bits: 443.2 E(85289): 4.1e-124 Smith-Waterman score: 2411; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC 310 320 330 340 350 360 >>NP_149421 (OMIM: 114610) cannabinoid receptor 1 isofor (439 aa) initn: 951 init1: 508 opt: 666 Z-score: 658.1 bits: 130.6 E(85289): 6.4e-30 Smith-Waterman score: 929; 48.7% identity (75.0% similar) in 300 aa overlap (25-307:75-372) 10 20 30 40 50 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAV .:.:. :. :.::: :: ...:::. : NP_149 ITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLV 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB7 LYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVT : .:: :..:: .::: :::::: ::.:.::.:. ::..::::: ::. :::.:.:.:: NP_149 LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVT 110 120 130 140 150 160 120 130 140 150 160 170 pF1KB7 MTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTC .::::::::.:::::::. .. : .:: ..:: .:.:.. .::... ... :::.::.: NP_149 ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC 170 180 190 200 210 220 180 190 200 210 220 pF1KB7 --CPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASL--SGHQ--- ::..:: : . ::. :. . :. :.:.: ..:::::.:.. . : : NP_149 EKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSI 230 240 250 260 270 280 230 240 250 260 270 pF1KB7 ------DRQV----PGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQV : .: : .::: :.:::::: :.:.::.::: :.::.:.... .. . NP_149 IIHTSEDGKVQVTRPDQARM--DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLI 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB7 KKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSV : .:::::::::.:: :::.:::::: ..: NP_149 KTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKH 350 360 370 380 390 400 >>XP_011533727 (OMIM: 114610) PREDICTED: cannabinoid rec (472 aa) initn: 951 init1: 508 opt: 666 Z-score: 657.8 bits: 130.7 E(85289): 6.7e-30 Smith-Waterman score: 929; 48.7% identity (75.0% similar) in 300 aa overlap (25-307:108-405) 10 20 30 40 50 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAV .:.:. :. :.::: :: ...:::. : XP_011 ITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLV 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB7 LYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVT : .:: :..:: .::: :::::: ::.:.::.:. ::..::::: ::. :::.:.:.:: XP_011 LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVT 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB7 MTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTC .::::::::.:::::::. .. : .:: ..:: .:.:.. .::... ... :::.::.: XP_011 ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC 200 210 220 230 240 250 180 190 200 210 220 pF1KB7 --CPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASL--SGHQ--- ::..:: : . ::. :. . :. :.:.: ..:::::.:.. . : : XP_011 EKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSI 260 270 280 290 300 310 230 240 250 260 270 pF1KB7 ------DRQV----PGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQV : .: : .::: :.:::::: :.:.::.::: :.::.:.... .. . XP_011 IIHTSEDGKVQVTRPDQARM--DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLI 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB7 KKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSV : .:::::::::.:: :::.:::::: ..: XP_011 KTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKH 380 390 400 410 420 430 >>XP_011533728 (OMIM: 114610) PREDICTED: cannabinoid rec (472 aa) initn: 951 init1: 508 opt: 666 Z-score: 657.8 bits: 130.7 E(85289): 6.7e-30 Smith-Waterman score: 929; 48.7% identity (75.0% similar) in 300 aa overlap (25-307:108-405) 10 20 30 40 50 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAV .:.:. :. :.::: :: ...:::. : XP_011 ITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLV 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB7 LYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVT : .:: :..:: .::: :::::: ::.:.::.:. ::..::::: ::. :::.:.:.:: XP_011 LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVT 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB7 MTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTC .::::::::.:::::::. .. : .:: ..:: .:.:.. .::... ... :::.::.: XP_011 ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC 200 210 220 230 240 250 180 190 200 210 220 pF1KB7 --CPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASL--SGHQ--- ::..:: : . ::. :. . :. :.:.: ..:::::.:.. . : : XP_011 EKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSI 260 270 280 290 300 310 230 240 250 260 270 pF1KB7 ------DRQV----PGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQV : .: : .::: :.:::::: :.:.::.::: :.::.:.... .. . XP_011 IIHTSEDGKVQVTRPDQARM--DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLI 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB7 KKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSV : .:::::::::.:: :::.:::::: ..: XP_011 KTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKH 380 390 400 410 420 430 >>XP_011533730 (OMIM: 114610) PREDICTED: cannabinoid rec (472 aa) initn: 951 init1: 508 opt: 666 Z-score: 657.8 bits: 130.7 E(85289): 6.7e-30 Smith-Waterman score: 929; 48.7% identity (75.0% similar) in 300 aa overlap (25-307:108-405) 10 20 30 40 50 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAV .:.:. :. :.::: :: ...:::. : XP_011 ITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLV 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB7 LYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVT : .:: :..:: .::: :::::: ::.:.::.:. ::..::::: ::. :::.:.:.:: XP_011 LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVT 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB7 MTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTC .::::::::.:::::::. .. : .:: ..:: .:.:.. .::... ... :::.::.: XP_011 ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC 200 210 220 230 240 250 180 190 200 210 220 pF1KB7 --CPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASL--SGHQ--- ::..:: : . ::. :. . :. :.:.: ..:::::.:.. . : : XP_011 EKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSI 260 270 280 290 300 310 230 240 250 260 270 pF1KB7 ------DRQV----PGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQV : .: : .::: :.:::::: :.:.::.::: :.::.:.... .. . XP_011 IIHTSEDGKVQVTRPDQARM--DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLI 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB7 KKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSV : .:::::::::.:: :::.:::::: ..: XP_011 KTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKH 380 390 400 410 420 430 >>XP_016865727 (OMIM: 114610) PREDICTED: cannabinoid rec (472 aa) initn: 951 init1: 508 opt: 666 Z-score: 657.8 bits: 130.7 E(85289): 6.7e-30 Smith-Waterman score: 929; 48.7% identity (75.0% similar) in 300 aa overlap (25-307:108-405) 10 20 30 40 50 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAV .:.:. :. :.::: :: ...:::. : XP_016 ITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLV 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB7 LYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVT : .:: :..:: .::: :::::: ::.:.::.:. ::..::::: ::. :::.:.:.:: XP_016 LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVT 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB7 MTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTC .::::::::.:::::::. .. : .:: ..:: .:.:.. .::... ... :::.::.: XP_016 ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC 200 210 220 230 240 250 180 190 200 210 220 pF1KB7 --CPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASL--SGHQ--- ::..:: : . ::. :. . :. :.:.: ..:::::.:.. . : : XP_016 EKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSI 260 270 280 290 300 310 230 240 250 260 270 pF1KB7 ------DRQV----PGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQV : .: : .::: :.:::::: :.:.::.::: :.::.:.... .. . XP_016 IIHTSEDGKVQVTRPDQARM--DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLI 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB7 KKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSV : .:::::::::.:: :::.:::::: ..: XP_016 KTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKH 380 390 400 410 420 430 >>XP_006715393 (OMIM: 114610) PREDICTED: cannabinoid rec (472 aa) initn: 951 init1: 508 opt: 666 Z-score: 657.8 bits: 130.7 E(85289): 6.7e-30 Smith-Waterman score: 929; 48.7% identity (75.0% similar) in 300 aa overlap (25-307:108-405) 10 20 30 40 50 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAV .:.:. :. :.::: :: ...:::. : XP_006 ITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLV 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB7 LYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVT : .:: :..:: .::: :::::: ::.:.::.:. ::..::::: ::. :::.:.:.:: XP_006 LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVT 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB7 MTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTC .::::::::.:::::::. .. : .:: ..:: .:.:.. .::... ... :::.::.: XP_006 ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC 200 210 220 230 240 250 180 190 200 210 220 pF1KB7 --CPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASL--SGHQ--- ::..:: : . ::. :. . :. :.:.: ..:::::.:.. . : : XP_006 EKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSI 260 270 280 290 300 310 230 240 250 260 270 pF1KB7 ------DRQV----PGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQV : .: : .::: :.:::::: :.:.::.::: :.::.:.... .. . XP_006 IIHTSEDGKVQVTRPDQARM--DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLI 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB7 KKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSV : .:::::::::.:: :::.:::::: ..: XP_006 KTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKH 380 390 400 410 420 430 >>XP_011533726 (OMIM: 114610) PREDICTED: cannabinoid rec (472 aa) initn: 951 init1: 508 opt: 666 Z-score: 657.8 bits: 130.7 E(85289): 6.7e-30 Smith-Waterman score: 929; 48.7% identity (75.0% similar) in 300 aa overlap (25-307:108-405) 10 20 30 40 50 pF1KB7 MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAV .:.:. :. :.::: :: ...:::. : XP_011 ITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLV 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB7 LYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVT : .:: :..:: .::: :::::: ::.:.::.:. ::..::::: ::. :::.:.:.:: XP_011 LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVT 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB7 MTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTC .::::::::.:::::::. .. : .:: ..:: .:.:.. .::... ... :::.::.: XP_011 ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC 200 210 220 230 240 250 180 190 200 210 220 pF1KB7 --CPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASL--SGHQ--- ::..:: : . ::. :. . :. :.:.: ..:::::.:.. . : : XP_011 EKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSI 260 270 280 290 300 310 230 240 250 260 270 pF1KB7 ------DRQV----PGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQV : .: : .::: :.:::::: :.:.::.::: :.::.:.... .. . XP_011 IIHTSEDGKVQVTRPDQARM--DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLI 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB7 KKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSV : .:::::::::.:: :::.:::::: ..: XP_011 KTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKH 380 390 400 410 420 430 360 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:21:34 2016 done: Fri Nov 4 05:21:36 2016 Total Scan time: 7.330 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]