FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7158, 363 aa 1>>>pF1KB7158 363 - 363 aa - 363 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7164+/-0.000535; mu= 20.3752+/- 0.033 mean_var=110.2201+/-26.571, 0's: 0 Z-trim(109.1): 715 B-trim: 1796 in 2/45 Lambda= 0.122164 statistics sampled from 16438 (17238) to 16438 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.534), E-opt: 0.2 (0.202), width: 16 Scan time: 7.180 The best scores are: opt bits E(85289) XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 2449 443.3 4.1e-124 NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 2449 443.3 4.1e-124 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 759 145.4 1.9e-34 NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 759 145.4 1.9e-34 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 759 145.5 1.9e-34 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 759 145.5 2e-34 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 759 145.5 2e-34 NP_000614 (OMIM: 113503) B2 bradykinin receptor [H ( 391) 658 127.7 4.5e-29 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 641 124.6 3.4e-28 NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 594 116.4 1.1e-25 XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 594 116.4 1.1e-25 XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 594 116.4 1.1e-25 NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 594 116.4 1.1e-25 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 591 115.8 1.6e-25 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 590 115.7 1.8e-25 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 590 115.7 1.9e-25 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 590 115.7 1.9e-25 NP_000701 (OMIM: 600337) B1 bradykinin receptor [H ( 353) 588 115.3 2.2e-25 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 585 114.7 3.2e-25 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 585 114.7 3.2e-25 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 585 114.7 3.2e-25 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 585 114.7 3.2e-25 NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 585 114.8 3.3e-25 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 569 111.9 2.2e-24 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 569 111.9 2.2e-24 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 569 112.0 2.3e-24 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 566 111.4 3.2e-24 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 566 111.4 3.2e-24 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 566 111.4 3.2e-24 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 566 111.4 3.3e-24 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 561 110.6 6.5e-24 XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 561 110.6 6.5e-24 NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 561 110.6 6.5e-24 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 561 110.6 6.5e-24 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 561 110.6 6.5e-24 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 561 110.6 6.5e-24 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 561 110.6 6.5e-24 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 560 110.3 6.7e-24 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 560 110.3 6.7e-24 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 560 110.3 6.7e-24 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 560 110.3 6.7e-24 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 560 110.3 6.7e-24 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 560 110.3 6.7e-24 NP_064707 (OMIM: 610376) atypical chemokine recept ( 362) 558 110.0 8.6e-24 XP_016860005 (OMIM: 610376) PREDICTED: atypical ch ( 362) 558 110.0 8.6e-24 XP_005246154 (OMIM: 610376) PREDICTED: atypical ch ( 362) 558 110.0 8.6e-24 XP_005246155 (OMIM: 610376) PREDICTED: atypical ch ( 362) 558 110.0 8.6e-24 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 556 109.6 1.1e-23 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 556 109.6 1.1e-23 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 556 109.7 1.1e-23 >>XP_011535835 (OMIM: 300034) PREDICTED: type-2 angioten (363 aa) initn: 2449 init1: 2449 opt: 2449 Z-score: 2349.3 bits: 443.3 E(85289): 4.1e-124 Smith-Waterman score: 2449; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363) 10 20 30 40 50 60 pF1KB7 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET 310 320 330 340 350 360 pF1KB7 FVS ::: XP_011 FVS >>NP_000677 (OMIM: 300034) type-2 angiotensin II recepto (363 aa) initn: 2449 init1: 2449 opt: 2449 Z-score: 2349.3 bits: 443.3 E(85289): 4.1e-124 Smith-Waterman score: 2449; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363) 10 20 30 40 50 60 pF1KB7 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET 310 320 330 340 350 360 pF1KB7 FVS ::: NP_000 FVS >>NP_033611 (OMIM: 106165,145500,267430) type-1 angioten (359 aa) initn: 723 init1: 627 opt: 759 Z-score: 739.6 bits: 145.4 E(85289): 1.9e-34 Smith-Waterman score: 759; 36.5% identity (72.1% similar) in 312 aa overlap (47-355:31-337) 20 30 40 50 60 70 pF1KB7 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP :: :: ::::.:.. : .::.... .: NP_033 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL- 10 20 30 40 50 80 90 100 110 120 130 pF1KB7 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI : :.:....:::.::: .: ::::::.: ...: : :: .::. .. ...:..::.:.. NP_033 KTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL 60 70 80 90 100 110 140 150 160 170 180 190 pF1KB7 TCMSVDRYQSVIYPFLSQ-RRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA ::.:.::: ....:. :. ::. :. ..: .: :.:::.. :.: :: .... NP_033 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV 120 130 140 150 160 170 200 210 220 230 240 250 pF1KB7 CIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQV : . . .. . :..: ::::::..:...: : : : : : :. ::. :.. NP_033 CAFHYESQN-STLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDI 180 190 200 210 220 230 260 270 280 290 300 310 pF1KB7 LKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVN .:. :.:: :.. :.: ...::::.: .:.: .:.. ..: :.:..: ... :.:.: NP_033 FKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLN 240 250 260 270 280 290 320 330 340 350 360 pF1KB7 PFLYCFVGNRFQQKLRSVFR-VPITWLQGKRESMSCRKSSSLREMETFVS :..: :.:..:.. . .... .: ..: .: : :.: NP_033 PLFYGFLGKKFKRYFLQLLKYIPP---KAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPC 300 310 320 330 340 350 NP_033 FEVE >>NP_000676 (OMIM: 106165,145500,267430) type-1 angioten (359 aa) initn: 723 init1: 627 opt: 759 Z-score: 739.6 bits: 145.4 E(85289): 1.9e-34 Smith-Waterman score: 759; 36.5% identity (72.1% similar) in 312 aa overlap (47-355:31-337) 20 30 40 50 60 70 pF1KB7 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP :: :: ::::.:.. : .::.... .: NP_000 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL- 10 20 30 40 50 80 90 100 110 120 130 pF1KB7 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI : :.:....:::.::: .: ::::::.: ...: : :: .::. .. ...:..::.:.. NP_000 KTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL 60 70 80 90 100 110 140 150 160 170 180 190 pF1KB7 TCMSVDRYQSVIYPFLSQ-RRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA ::.:.::: ....:. :. ::. :. ..: .: :.:::.. :.: :: .... NP_000 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV 120 130 140 150 160 170 200 210 220 230 240 250 pF1KB7 CIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQV : . . .. . :..: ::::::..:...: : : : : : :. ::. :.. NP_000 CAFHYESQN-STLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDI 180 190 200 210 220 230 260 270 280 290 300 310 pF1KB7 LKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVN .:. :.:: :.. :.: ...::::.: .:.: .:.. ..: :.:..: ... :.:.: NP_000 FKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLN 240 250 260 270 280 290 320 330 340 350 360 pF1KB7 PFLYCFVGNRFQQKLRSVFR-VPITWLQGKRESMSCRKSSSLREMETFVS :..: :.:..:.. . .... .: ..: .: : :.: NP_000 PLFYGFLGKKFKRYFLQLLKYIPP---KAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPC 300 310 320 330 340 350 NP_000 FEVE >>NP_114438 (OMIM: 106165,145500,267430) type-1 angioten (388 aa) initn: 723 init1: 627 opt: 759 Z-score: 739.2 bits: 145.5 E(85289): 1.9e-34 Smith-Waterman score: 759; 36.5% identity (72.1% similar) in 312 aa overlap (47-355:60-366) 20 30 40 50 60 70 pF1KB7 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP :: :: ::::.:.. : .::.... .: NP_114 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL- 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB7 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI : :.:....:::.::: .: ::::::.: ...: : :: .::. .. ...:..::.:.. NP_114 KTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL 90 100 110 120 130 140 140 150 160 170 180 190 pF1KB7 TCMSVDRYQSVIYPFLSQ-RRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA ::.:.::: ....:. :. ::. :. ..: .: :.:::.. :.: :: .... NP_114 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV 150 160 170 180 190 200 200 210 220 230 240 250 pF1KB7 CIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQV : . . .. . :..: ::::::..:...: : : : : : :. ::. :.. NP_114 CAFHYESQN-STLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDI 210 220 230 240 250 260 260 270 280 290 300 310 pF1KB7 LKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVN .:. :.:: :.. :.: ...::::.: .:.: .:.. ..: :.:..: ... :.:.: NP_114 FKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLN 270 280 290 300 310 320 320 330 340 350 360 pF1KB7 PFLYCFVGNRFQQKLRSVFR-VPITWLQGKRESMSCRKSSSLREMETFVS :..: :.:..:.. . .... .: ..: .: : :.: NP_114 PLFYGFLGKKFKRYFLQLLKYIPP---KAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPC 330 340 350 360 370 380 NP_114 FEVE >>NP_004826 (OMIM: 106165,145500,267430) type-1 angioten (394 aa) initn: 723 init1: 627 opt: 759 Z-score: 739.2 bits: 145.5 E(85289): 2e-34 Smith-Waterman score: 759; 36.5% identity (72.1% similar) in 312 aa overlap (47-355:66-372) 20 30 40 50 60 70 pF1KB7 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP :: :: ::::.:.. : .::.... .: NP_004 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL- 40 50 60 70 80 90 80 90 100 110 120 130 pF1KB7 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI : :.:....:::.::: .: ::::::.: ...: : :: .::. .. ...:..::.:.. NP_004 KTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL 100 110 120 130 140 150 140 150 160 170 180 190 pF1KB7 TCMSVDRYQSVIYPFLSQ-RRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA ::.:.::: ....:. :. ::. :. ..: .: :.:::.. :.: :: .... NP_004 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV 160 170 180 190 200 210 200 210 220 230 240 250 pF1KB7 CIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQV : . . .. . :..: ::::::..:...: : : : : : :. ::. :.. NP_004 CAFHYESQN-STLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDI 220 230 240 250 260 270 260 270 280 290 300 310 pF1KB7 LKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVN .:. :.:: :.. :.: ...::::.: .:.: .:.. ..: :.:..: ... :.:.: NP_004 FKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLN 280 290 300 310 320 330 320 330 340 350 360 pF1KB7 PFLYCFVGNRFQQKLRSVFR-VPITWLQGKRESMSCRKSSSLREMETFVS :..: :.:..:.. . .... .: ..: .: : :.: NP_004 PLFYGFLGKKFKRYFLQLLKYIPP---KAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPC 340 350 360 370 380 390 NP_004 FEVE >>NP_114038 (OMIM: 106165,145500,267430) type-1 angioten (394 aa) initn: 723 init1: 627 opt: 759 Z-score: 739.2 bits: 145.5 E(85289): 2e-34 Smith-Waterman score: 759; 36.5% identity (72.1% similar) in 312 aa overlap (47-355:66-372) 20 30 40 50 60 70 pF1KB7 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP :: :: ::::.:.. : .::.... .: NP_114 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL- 40 50 60 70 80 90 80 90 100 110 120 130 pF1KB7 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI : :.:....:::.::: .: ::::::.: ...: : :: .::. .. ...:..::.:.. NP_114 KTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL 100 110 120 130 140 150 140 150 160 170 180 190 pF1KB7 TCMSVDRYQSVIYPFLSQ-RRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA ::.:.::: ....:. :. ::. :. ..: .: :.:::.. :.: :: .... NP_114 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV 160 170 180 190 200 210 200 210 220 230 240 250 pF1KB7 CIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQV : . . .. . :..: ::::::..:...: : : : : : :. ::. :.. NP_114 CAFHYESQN-STLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDI 220 230 240 250 260 270 260 270 280 290 300 310 pF1KB7 LKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVN .:. :.:: :.. :.: ...::::.: .:.: .:.. ..: :.:..: ... :.:.: NP_114 FKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLN 280 290 300 310 320 330 320 330 340 350 360 pF1KB7 PFLYCFVGNRFQQKLRSVFR-VPITWLQGKRESMSCRKSSSLREMETFVS :..: :.:..:.. . .... .: ..: .: : :.: NP_114 PLFYGFLGKKFKRYFLQLLKYIPP---KAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPC 340 350 360 370 380 390 NP_114 FEVE >>NP_000614 (OMIM: 113503) B2 bradykinin receptor [Homo (391 aa) initn: 531 init1: 304 opt: 658 Z-score: 643.0 bits: 127.7 E(85289): 4.5e-29 Smith-Waterman score: 658; 33.7% identity (65.3% similar) in 323 aa overlap (35-350:47-357) 10 20 30 40 50 60 pF1KB7 STLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAI-PILYYIIFVIGFLVNI : : :..: : . ...::.. : :: NP_000 SVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENI 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB7 VVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSF :...:: .:. :. ::. :::.:::.: ::.:: : .::::: ..:.: ... NP_000 FVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAI 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB7 LTLNMFASIFFITCMSVDRYQSVIYPF-LSQRRNPWQASYIVPLVW-CMACLSSLPTFYF ...:...:: :. .:.::: ... . ... :. :. ..: : ::: : . : NP_000 ISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSS-PMLVF 140 150 160 170 180 190 190 200 210 220 230 pF1KB7 RDVRTIEYLG--VNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLL : .. : :.::....: : . .. :..::..:: :. : . : . .: NP_000 RTMKEYSDEGHNVTACVISYPS---LIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQ-VL 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB7 KTNSYGKNR--ITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVID ..: . : . :. .. .. .:.: ::::::::.. ::::.: .:...::. .:: NP_000 RNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIID 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB7 LALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLRE . .: .....:::.::..: .::.::..: :. :: .. .:: NP_000 VITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVY-------QGVCQKGGCRSEPIQME 320 330 340 350 360 360 pF1KB7 METFVS NP_000 NSMGTLRTSISVERQIHKLQDWAGSRQ 370 380 390 >>NP_001286 (OMIM: 601159) C-C chemokine receptor type 1 (355 aa) initn: 437 init1: 192 opt: 641 Z-score: 627.2 bits: 124.6 E(85289): 3.4e-28 Smith-Waterman score: 641; 32.8% identity (65.3% similar) in 314 aa overlap (35-340:24-328) 10 20 30 40 50 60 pF1KB7 STLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDA--IPILYYIIFVIGFLVN : :: ... . : .: :: ..::::.. : NP_001 METPNTTEDYDTTTEFDYGDATPC-QKVNERAFGAQLLPPLYSLVFVIGLVGN 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 IVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGS :.:: .. : :...:::..:::..:::.: :::.: : . . ::.:: .:::.... NP_001 ILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDY-KLKDDWVFGDAMCKILSG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 FLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLV-WCMACLSSLPTFYF : .... :::: ...::: .... .. : . :. .. : .: :.:.: .:: NP_001 FYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 RDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKT .: . ..: . :: :. .:. :: :..:...::. . :: :: : ::. NP_001 S--KTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRR 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 NSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALP . :.. .: . .... :.. : :... ..... . . :: .:::. NP_001 PNEKKSKAVR-----LIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQ 230 240 250 260 270 280 310 320 330 340 350 pF1KB7 FAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF--RVPI---TWLQGKRESMSCRKSSSLR . ....:. :::: .: :::.::.. ::..: :: . :: NP_001 VTEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSP 290 300 310 320 330 340 360 pF1KB7 EMETFVS NP_001 STGEHELSAGF 350 >>NP_001495 (OMIM: 300574) C-X-C chemokine receptor type (368 aa) initn: 502 init1: 149 opt: 594 Z-score: 582.3 bits: 116.4 E(85289): 1.1e-25 Smith-Waterman score: 594; 30.2% identity (63.9% similar) in 341 aa overlap (27-357:30-359) 10 20 30 40 50 pF1KB7 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDA------IPILY :.::: :.. : . .. .: :: NP_001 MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 YIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWL ..:..:.: : .:.... .. . .. ....::::: ::. ::::::. . . :. NP_001 SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQ--WV 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 FGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL-VWCM :: .::: :.....:..:. ....:.: ::: .... ::.: .. : :: . NP_001 FGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 ACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATC : .:: : : ... : :... : . :: . .. ... . ::..::. .: : NP_001 CLLFALPDFIFLSAHHDERLNATHCQYNFPQVGRT----ALRVLQLVAGFLLPLLVMAYC 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 YFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVIN-S : : :: : :. :. ........::.:: .:: :.:.....: : .:.. . NP_001 YAHILAVLLV--SRGQRRL---RAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARN 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 CEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVF-RVPITWLQG-KRESM : . .:.: . ::. . :.::.:: ::: .:.... .. :. .: .:. NP_001 CGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPS 290 300 310 320 330 340 350 360 pF1KB7 SCRKSSSLREMETFVS : :..:: : NP_001 SSRRDSSWSETSEASYSGL 350 360 363 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:22:06 2016 done: Fri Nov 4 05:22:07 2016 Total Scan time: 7.180 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]