Result of FASTA (omim) for
pF1KB7166
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7166, 396 aa
1>>>pF1KB7166 396 - 396 aa - 396 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8657+/-0.000333; mu= 15.2656+/- 0.021
mean_var=87.3560+/-17.003, 0's: 0 Z-trim(116.7): 47 B-trim: 0 in 0/56
Lambda= 0.137223
statistics sampled from 28016 (28065) to 28016 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.329), width: 16
Scan time: 8.200
The best scores are: opt bits E(85289)
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 2689 542.1 8.8e-154
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 2689 542.1 8.8e-154
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 2689 542.1 8.8e-154
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 2689 542.1 8.8e-154
NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 663 141.0 5.3e-33
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 464 101.6 3.7e-21
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 464 101.6 3.8e-21
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 464 101.6 3.8e-21
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 462 101.2 5e-21
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 462 101.2 5e-21
NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 449 98.6 2.5e-20
NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 449 98.6 2.5e-20
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 449 98.6 2.5e-20
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 449 98.6 2.5e-20
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 438 96.4 1.1e-19
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 438 96.4 1.1e-19
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 438 96.4 1.1e-19
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 438 96.5 1.6e-19
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 432 95.3 3.5e-19
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 416 92.0 2.2e-18
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 405 89.9 1.1e-17
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 388 86.4 9e-17
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 386 86.0 1.2e-16
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 386 86.0 1.2e-16
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 386 86.0 1.2e-16
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 386 86.0 1.2e-16
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 384 85.7 1.6e-16
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 377 84.2 3.4e-16
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 377 84.2 3.4e-16
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 377 84.3 4e-16
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 374 83.7 5.9e-16
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 374 83.7 5.9e-16
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 369 82.7 1.2e-15
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 369 82.7 1.2e-15
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 369 82.7 1.2e-15
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 369 82.7 1.2e-15
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 369 82.7 1.2e-15
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 369 82.7 1.2e-15
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 369 82.7 1.2e-15
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 369 82.7 1.2e-15
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 354 79.6 8e-15
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 354 79.6 8e-15
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 343 77.5 4.2e-14
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 343 77.5 4.2e-14
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 342 77.3 4.8e-14
NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 342 77.3 4.8e-14
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 327 74.4 4.9e-13
>>NP_001073852 (OMIM: 608655) gap junction gamma-1 prote (396 aa)
initn: 2689 init1: 2689 opt: 2689 Z-score: 2881.8 bits: 542.1 E(85289): 8.8e-154
Smith-Waterman score: 2689; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQN
310 320 330 340 350 360
370 380 390
pF1KB7 NPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
::::::::::::::::::::::::::::::::::::
NP_001 NPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
370 380 390
>>NP_005488 (OMIM: 608655) gap junction gamma-1 protein (396 aa)
initn: 2689 init1: 2689 opt: 2689 Z-score: 2881.8 bits: 542.1 E(85289): 8.8e-154
Smith-Waterman score: 2689; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQN
310 320 330 340 350 360
370 380 390
pF1KB7 NPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
::::::::::::::::::::::::::::::::::::
NP_005 NPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
370 380 390
>>XP_005256978 (OMIM: 608655) PREDICTED: gap junction ga (396 aa)
initn: 2689 init1: 2689 opt: 2689 Z-score: 2881.8 bits: 542.1 E(85289): 8.8e-154
Smith-Waterman score: 2689; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQN
310 320 330 340 350 360
370 380 390
pF1KB7 NPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
::::::::::::::::::::::::::::::::::::
XP_005 NPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
370 380 390
>>XP_005256977 (OMIM: 608655) PREDICTED: gap junction ga (396 aa)
initn: 2689 init1: 2689 opt: 2689 Z-score: 2881.8 bits: 542.1 E(85289): 8.8e-154
Smith-Waterman score: 2689; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQN
310 320 330 340 350 360
370 380 390
pF1KB7 NPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
::::::::::::::::::::::::::::::::::::
XP_005 NPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
370 380 390
>>NP_065168 (OMIM: 608803,608804,613206,613480) gap junc (439 aa)
initn: 1211 init1: 631 opt: 663 Z-score: 713.5 bits: 141.0 E(85289): 5.3e-33
Smith-Waterman score: 1174; 46.5% identity (68.8% similar) in 432 aa overlap (1-386:4-431)
10 20 30 40 50
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQ
::::::::::::::::::::::.:::::.::::::::::::.:: :::.::.:::.:
NP_065 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 PGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPY
:::.::::::::::::::::::::....::::::::::.:..:. . : ..: : .:
NP_065 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQER-RRALRRRPG
70 80 90 100 110
120 130 140 150
pF1KB7 AMRWKQ------HRALEETEEDNEEDPMM-YPEMELESDK--------------------
: . : . : . .::.::. : : : .
NP_065 PRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACT
120 130 140 150 160 170
160 170 180 190 200
pF1KB7 -----ENKEQSQPKP--KHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQV
..: . : : .:::::::...:::..:: ::.::..:::.::.:::.::::.:
NP_065 KAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 HPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLN
.::. ::: :::: .:::.:::::::.:::.:: :. ::::::. :: :::.:. .:..
NP_065 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
240 250 260 270 280 290
270 280 290 300 310
pF1KB7 SKRRELED-PGAYNYPFTWNTPSA------PPGYNIAVKPDQ---IQYTELSNAKIAYKQ
..: . :. : :.: :: :...:. . . .:.: . .
NP_065 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB7 NKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYS--HQNNPHGPREKKAK
. : ...... .: .::: .. : :. : :..: . .:. : : .:. .
NP_065 DGAAAGDRDRDSSPCVGLPAASRGPPRAGAPAS-RTGSATSAGTVGEQGRP-GTHERPG-
360 370 380 390 400 410
380 390
pF1KB7 VGSKAGSNKSTASSKSGDGKTSVWI
. .:::.:..:::.
NP_065 AKPRAGSEKGSASSRDGKTTVWI
420 430
>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g (427 aa)
initn: 817 init1: 454 opt: 464 Z-score: 500.8 bits: 101.6 E(85289): 3.7e-21
Smith-Waterman score: 799; 44.6% identity (72.3% similar) in 271 aa overlap (3-272:4-243)
10 20 30 40 50
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPG
:::: .:::...::: .:..:::::..:::.. ....: .. :::: :::::.:::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 CENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAM
::::::: :.::.:.::.:::.:.:::.::.:.:.: . .:: .:. .:
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV-RME----EKRKSR------
70 80 90 100
120 130 140 150 160 170
pF1KB7 RWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYV
: : .. :.. :..: : : ...: .: :.. :.
XP_011 --------EAEELGQQAGTNGGPDQ-----GSVKKSSGSK----GTKKFRLEGTLLRTYI
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 LQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGV
... .:.:::::..:.::::::.. :.: ::: :::. .:::.:::::::::.:.: .:
XP_011 CHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 TGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQ
... :.::. :. :::. ::..: .: .:.:
XP_011 ASVSLFLNVMELGHLGLKGIRSAL---KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLL
220 230 240 250 260
300 310 320 330 340 350
pF1KB7 IQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSH
XP_011 EEEKIVSHYFPLTEVGMVETSPLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQ
270 280 290 300 310 320
>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g (433 aa)
initn: 817 init1: 454 opt: 464 Z-score: 500.7 bits: 101.6 E(85289): 3.8e-21
Smith-Waterman score: 799; 44.6% identity (72.3% similar) in 271 aa overlap (3-272:4-243)
10 20 30 40 50
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPG
:::: .:::...::: .:..:::::..:::.. ....: .. :::: :::::.:::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 CENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAM
::::::: :.::.:.::.:::.:.:::.::.:.:.: . .:: .:. .:
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV-RME----EKRKSR------
70 80 90 100
120 130 140 150 160 170
pF1KB7 RWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYV
: : .. :.. :..: : : ...: .: :.. :.
XP_011 --------EAEELGQQAGTNGGPDQ-----GSVKKSSGSK----GTKKFRLEGTLLRTYI
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 LQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGV
... .:.:::::..:.::::::.. :.: ::: :::. .:::.:::::::::.:.: .:
XP_011 CHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 TGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQ
... :.::. :. :::. ::..: .: .:.:
XP_011 ASVSLFLNVMELGHLGLKGIRSAL---KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLL
220 230 240 250 260
300 310 320 330 340 350
pF1KB7 IQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSH
XP_011 EEEKIVSHYFPLTEVGMVETSPLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQ
270 280 290 300 310 320
>>NP_005258 (OMIM: 116200,600897,612474) gap junction al (433 aa)
initn: 817 init1: 454 opt: 464 Z-score: 500.7 bits: 101.6 E(85289): 3.8e-21
Smith-Waterman score: 799; 44.6% identity (72.3% similar) in 271 aa overlap (3-272:4-243)
10 20 30 40 50
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPG
:::: .:::...::: .:..:::::..:::.. ....: .. :::: :::::.:::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 CENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAM
::::::: :.::.:.::.:::.:.:::.::.:.:.: . .:: .:. .:
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV-RME----EKRKSR------
70 80 90 100
120 130 140 150 160 170
pF1KB7 RWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYV
: : .. :.. :..: : : ...: .: :.. :.
NP_005 --------EAEELGQQAGTNGGPDQ-----GSVKKSSGSK----GTKKFRLEGTLLRTYI
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 LQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGV
... .:.:::::..:.::::::.. :.: ::: :::. .:::.:::::::::.:.: .:
NP_005 CHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 TGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQ
... :.::. :. :::. ::..: .: .:.:
NP_005 ASVSLFLNVMELGHLGLKGIRSAL---KRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLL
220 230 240 250 260
300 310 320 330 340 350
pF1KB7 IQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSH
NP_005 EEEKIVSHYFPLTEVGMVETSPLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQ
270 280 290 300 310 320
>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p (435 aa)
initn: 823 init1: 443 opt: 462 Z-score: 498.5 bits: 101.2 E(85289): 5e-21
Smith-Waterman score: 834; 38.2% identity (64.3% similar) in 398 aa overlap (3-376:4-359)
10 20 30 40 50
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPG
:::: ::::. ..::: .::.:::::..:::.. ....:... :::: :.:::.:::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 CENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAM
::::::: :.::.:::..:::.:.::...:::...: :..:: .:: :
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLH-IVRME----EKKKER------
70 80 90 100
120 130 140 150 160 170
pF1KB7 RWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYV
:: :. ..:.: : :: :..:. . : : :.: : :.. ::
NP_068 --------EEEEQLKRESP---------SPKE-PPQDNPSSRDD-RGRVRMAGALLRTYV
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 LQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGV
.... .:.:::::. ::::::::...:.: :.: :::. .:::::::::::::...: .:
NP_068 FNIIFKTLFEVGFIAGQYFLYGFELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 TGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTP------SAPPGYNI
. ::::. :. :::. ......:. : : . :. : : ::. :
NP_068 ACASLLLNMLEIYHLGWKKLKQGVTSRL----GPDASEAPLGTADPPPLPPSSRPPAVAI
220 230 240 250 260
300 310 320 330
pF1KB7 AVKPDQIQYTE-LSNAK----------------IAYKQNKANTAQEQQYGSHEENLPADL
. : . . :..:. .: . ... . . :..:.. : ..
NP_068 GFPPYYAHTAAPLGQARAVGYPGAPPPAADFKLLALTEARGKGQSAKLYNGHHHLLMTE-
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB7 EALQREIRMAQERLDLAVQAYSHQNNPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVW
: .: :: :..:: ..: .: . :::..
NP_068 ---QNWANQAAERQPPALKAYPAASTPAAP----SPVGSSSPPLAHEAEAGAAPLLLDGS
330 340 350 360 370
pF1KB7 I
NP_068 GSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKASRASSGRARPEDLAI
380 390 400 410 420 430
>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc (435 aa)
initn: 823 init1: 443 opt: 462 Z-score: 498.5 bits: 101.2 E(85289): 5e-21
Smith-Waterman score: 834; 38.2% identity (64.3% similar) in 398 aa overlap (3-376:4-359)
10 20 30 40 50
pF1KB7 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPG
:::: ::::. ..::: .::.:::::..:::.. ....:... :::: :.:::.:::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 CENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAM
::::::: :.::.:::..:::.:.::...:::...: :..:: .:: :
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLH-IVRME----EKKKER------
70 80 90 100
120 130 140 150 160 170
pF1KB7 RWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYV
:: :. ..:.: : :: :..:. . : : :.: : :.. ::
XP_011 --------EEEEQLKRESP---------SPKE-PPQDNPSSRDD-RGRVRMAGALLRTYV
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 LQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGV
.... .:.:::::. ::::::::...:.: :.: :::. .:::::::::::::...: .:
XP_011 FNIIFKTLFEVGFIAGQYFLYGFELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 TGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTP------SAPPGYNI
. ::::. :. :::. ......:. : : . :. : : ::. :
XP_011 ACASLLLNMLEIYHLGWKKLKQGVTSRL----GPDASEAPLGTADPPPLPPSSRPPAVAI
220 230 240 250 260
300 310 320 330
pF1KB7 AVKPDQIQYTE-LSNAK----------------IAYKQNKANTAQEQQYGSHEENLPADL
. : . . :..:. .: . ... . . :..:.. : ..
XP_011 GFPPYYAHTAAPLGQARAVGYPGAPPPAADFKLLALTEARGKGQSAKLYNGHHHLLMTE-
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB7 EALQREIRMAQERLDLAVQAYSHQNNPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVW
: .: :: :..:: ..: .: . :::..
XP_011 ---QNWANQAAERQPPALKAYPAASTPAAP----SPVGSSSPPLAHEAEAGAAPLLLDGS
330 340 350 360 370
pF1KB7 I
XP_011 GSSLEGSALAGTPEEEEQAVTTAAQMHQPPLPLGDPGRASKASRASSGRARPEDLAI
380 390 400 410 420 430
396 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:25:22 2016 done: Fri Nov 4 05:25:23 2016
Total Scan time: 8.200 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]