FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7170, 439 aa 1>>>pF1KB7170 439 - 439 aa - 439 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5998+/-0.000776; mu= 11.4452+/- 0.047 mean_var=207.2680+/-41.482, 0's: 0 Z-trim(116.2): 22 B-trim: 125 in 1/53 Lambda= 0.089086 statistics sampled from 16758 (16779) to 16758 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.515), width: 16 Scan time: 2.850 The best scores are: opt bits E(32554) CCDS1569.1 GJC2 gene_id:57165|Hs108|chr1 ( 439) 3014 399.3 3.9e-111 CCDS11487.1 GJC1 gene_id:10052|Hs108|chr17 ( 396) 663 97.1 3.3e-20 CCDS9289.1 GJA3 gene_id:2700|Hs108|chr13 ( 435) 471 72.5 9.6e-13 CCDS5025.1 GJA10 gene_id:84694|Hs108|chr6 ( 543) 455 70.5 4.6e-12 CCDS30834.1 GJA8 gene_id:2703|Hs108|chr1 ( 433) 452 70.0 5.2e-12 CCDS30669.1 GJA4 gene_id:2701|Hs108|chr1 ( 333) 449 69.5 5.7e-12 CCDS929.1 GJA5 gene_id:2702|Hs108|chr1 ( 358) 446 69.2 7.8e-12 CCDS432.1 GJA9 gene_id:81025|Hs108|chr1 ( 515) 434 67.8 2.9e-11 CCDS10040.1 GJD2 gene_id:57369|Hs108|chr15 ( 321) 417 65.4 9.6e-11 >>CCDS1569.1 GJC2 gene_id:57165|Hs108|chr1 (439 aa) initn: 3014 init1: 3014 opt: 3014 Z-score: 2108.6 bits: 399.3 E(32554): 3.9e-111 Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 439 aa overlap (1-439:1-439) 10 20 30 40 50 60 pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 AVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 PFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 RRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 RRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 GAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAKPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS15 GAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAKPR 370 380 390 400 410 420 430 pF1KB7 AGSEKGSASSRDGKTTVWI ::::::::::::::::::: CCDS15 AGSEKGSASSRDGKTTVWI 430 >>CCDS11487.1 GJC1 gene_id:10052|Hs108|chr17 (396 aa) initn: 1211 init1: 631 opt: 663 Z-score: 476.2 bits: 97.1 E(32554): 3.3e-20 Smith-Waterman score: 1214; 47.1% identity (68.8% similar) in 442 aa overlap (4-439:1-396) 10 20 30 40 50 60 pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ ::::::::::::::::::::::.:::::.::::::::::::.:: :::.::.:::.: CCDS11 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQ 10 20 30 40 50 70 80 90 100 110 pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQER-RRALRRRPG :::.::::::::::::::::::::....::::::::::.:..:. . : ..: : .: CCDS11 PGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACT : . : . : . .::.::. : : :. CCDS11 AMRWKQ------HRALEETEEDNEEDPMM---YPEMELESDK------------------ 120 130 140 150 180 190 200 210 220 230 pF1KB7 KAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEV ..: . : : .:::::::...:::..:: ::.::..:::.::.:::.::::.: CCDS11 -----ENKEQSQPKP--KHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQV 160 170 180 190 200 240 250 260 270 280 290 pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR .::. ::: :::: .:::.:::::::.:::.:: :. ::::::. :: :::.:. .:.. CCDS11 HPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLN 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR ..: :. : :.: :: :...:. . . .:.: . . CCDS11 SKRRE-LEDPGAYNYPFTWNTPSA------PPGYNIAVKPDQ---IQYTELSNAKIAYKQ 270 280 290 300 310 360 370 380 390 400 410 pF1KB7 DGAAAGDRDRDSSPCVGLPAASRGPPRAGAPAS-RTGSATSAGTVGEQGRP-GTHERPG- . : ...... .: .::: .. : :. : :..: . .:. : : .:. . CCDS11 NKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYS--HQNNPHGPREKKAK 320 330 340 350 360 370 420 430 pF1KB7 AKPRAGSEKGSASSR--DGKTTVWI . .:::.:..:::. ::::.::: CCDS11 VGSKAGSNKSTASSKSGDGKTSVWI 380 390 >>CCDS9289.1 GJA3 gene_id:2700|Hs108|chr13 (435 aa) initn: 865 init1: 438 opt: 471 Z-score: 342.3 bits: 72.5 E(32554): 9.6e-13 Smith-Waterman score: 839; 36.4% identity (59.3% similar) in 450 aa overlap (6-433:4-384) 10 20 30 40 50 60 pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ :::: ::::. ..::: .:::::::: .:::.. ....: ...:::. :::::.: CCDS92 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP :::.::::: :.::.:::..::. .:::...:::...: ..: :....: ... CCDS92 PGCENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLH-IVRMEEKKKERE-EEEQLK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK :..: . :: ...: CCDS92 RESPSPKEPP------------QDNP---------------------------------- 120 130 190 200 210 220 230 pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLYGFEV ...: : :.. : :.:.:: ... .. :::.:..:::.:::::. CCDS92 ---------------SSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFEL 140 150 160 170 240 250 260 270 280 290 pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR .:.. :.: :::..::::.:::::::.:.. : .:.: ::::. :. ::: . ...: CCDS92 KPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVT 180 190 200 210 220 230 300 310 320 330 340 pF1KB7 GRRGPPAS-APA----PAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARA-----HDQN .: :: :: :: : : :: ::.: :. :: :. .. .::: CCDS92 SRLGPDASEAPLGTADPPPLPPSSRPPAVAIGF--PPYYAHTAAPLGQARAVGYPGAPPP 240 250 260 270 280 290 350 360 370 380 390 pF1KB7 LANLALQALRDGAAAGDRDRDSSPCVGL---------PAASRGPPRAGA-PASRTGSATS :.. : :: .. . :. . . : :: : :: : ::. : .: : CCDS92 AADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPS 300 310 320 330 340 350 400 410 420 430 pF1KB7 AGTVGEQGRPGTHE-RPGAKPRAGSEKGSASSRDGKTTVWI :: .. : .:: . :: : . ::.:: .: CCDS92 P--VGSSSPPLAHEAEAGAAPLLLD--GSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPL 360 370 380 390 400 CCDS92 PLGDPGRASKASRASSGRARPEDLAI 410 420 430 >>CCDS5025.1 GJA10 gene_id:84694|Hs108|chr6 (543 aa) initn: 786 init1: 420 opt: 455 Z-score: 330.0 bits: 70.5 E(32554): 4.6e-12 Smith-Waterman score: 713; 36.9% identity (64.1% similar) in 309 aa overlap (6-305:4-258) 10 20 30 40 50 60 pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ :..: .:::.:.:::.:::.:::.: .::... :..: ...:::. :.::::: CCDS50 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP :::.:.::: :.: .::::.::. .:.::..:.:.:..:: :: :..:.: CCDS50 PGCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRL-RAFEKDRQRK------- 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK . ::.. : : . .: : . ::... . : : CCDS50 KSHLRAQMENPDLDLEEQQRIDRE-----LRRLEEQKRIHKVPLKG-----------C-- 120 130 140 150 190 200 210 220 230 240 pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVR :.:.:: ....:...::.:..:::.::::... CCDS50 ----------------------------LLRTYVLHILTRSVLEVGFMIGQYILYGFQMH 160 170 180 250 260 270 280 290 pF1KB7 PFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGL--------- :.. :.. :::..::::::::::::.:.: :. .. . ::::. :. :::. CCDS50 PLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYK 190 200 210 220 230 240 300 310 320 330 340 350 pF1KB7 GSAQDAVRGRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLA :...... . ::: CCDS50 KSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVPKSKTMWQ 250 260 270 280 290 300 >>CCDS30834.1 GJA8 gene_id:2703|Hs108|chr1 (433 aa) initn: 795 init1: 450 opt: 452 Z-score: 329.1 bits: 70.0 E(32554): 5.2e-12 Smith-Waterman score: 737; 33.6% identity (59.3% similar) in 425 aa overlap (6-428:4-353) 10 20 30 40 50 60 pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ :::: .:::...::: .:.:::::: .:::.. ....: ...:::. :.:::.: CCDS30 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP :::.::::: :.::.:.::.::. .::::.::.:.::: . : :... : CCDS30 PGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV-RMEEKRKSR-------- 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK : :: : :.. .: ... .: CCDS30 ----------------------------------EAEELGQQAGTN-----GGPDQGSVK 110 120 130 190 200 210 220 230 pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLYGFEV :..:. : .... :: :.:.:. ... .. :::.:.::.:.::::.. CCDS30 ------KSSGSKGT-------KKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRI 140 150 160 170 240 250 260 270 280 290 pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR :.. ::: :::.:::::::::::::.:.: : :. . :.::. :..:::: . ..:.. CCDS30 LPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALK 180 190 200 210 220 230 300 310 320 330 340 350 pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR : :. : . : :.... :.:. :. .: :..... CCDS30 -R---PVEQPL-GEIPEKSLHSIAVSSIQKAKGYQLL--EEEKIVSHYFPLTEVGMVETS 240 250 260 270 280 290 360 370 380 390 400 410 pF1KB7 DGAAAGDRDRDSSPCVG-LPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAK : . . . .: : ::: .. ...:. : .: :. . ::. CCDS30 PLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEG----EGPPA---EEGAE 300 310 320 330 340 420 430 pF1KB7 PRAGSEKGSASSRDGKTTVWI :..: .: : CCDS30 PEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPS 350 360 370 380 390 400 >>CCDS30669.1 GJA4 gene_id:2701|Hs108|chr1 (333 aa) initn: 784 init1: 422 opt: 449 Z-score: 328.4 bits: 69.5 E(32554): 5.7e-12 Smith-Waterman score: 724; 35.7% identity (60.1% similar) in 401 aa overlap (6-399:4-328) 10 20 30 40 50 60 pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ :.:: .::.....::: :::.::::: .:::.. ...::....:::. : ::: : CCDS30 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP ::: ::::: :.::.:.::.:.. .:::...:::.... :.: :.. ::.. : CCDS30 PGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIY-LSR-----REERLRQKEGE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK :: :: ..:.. : :..:. .: CCDS30 LRA----LPA-------------KDPQV-------------------ERALAAVERQMAK 120 130 190 200 210 220 230 240 pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVR :. ::: :: : .:: .:::... ....:..:: ::. :::. .. CCDS30 ISVAE-------------DGRLRI-RGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTME 140 150 160 170 180 250 260 270 280 290 300 pF1KB7 PFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRG : : :.: :::..::::::::::::.:.. : ::. . :.::: :..:: . ..:. CCDS30 PVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRA 190 200 210 220 230 240 310 320 330 340 350 pF1KB7 RRG---PPASAPAPAPRPPPCAF--PAAAAGLACP-PDYSLVVRAAERARAHDQNLANLA :.: ::... . : : :.. . . : : :. . . .:: :::. CCDS30 RQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGL-------SSSEQNWANLT 250 260 270 280 290 360 370 380 390 400 410 pF1KB7 LQALRDGAAAGDRDRDSSPCVGLPAASRGPPRAGA-PASRTGSATSAGTVGEQGRPGTHE . .: .: : : ::. : : :: .:..: CCDS30 TE---------ERLASSRP----PLFLDPPPQNGQKPPSRPSSSASKKQYV 300 310 320 330 420 430 pF1KB7 RPGAKPRAGSEKGSASSRDGKTTVWI >>CCDS929.1 GJA5 gene_id:2702|Hs108|chr1 (358 aa) initn: 715 init1: 433 opt: 446 Z-score: 326.0 bits: 69.2 E(32554): 7.8e-12 Smith-Waterman score: 684; 34.2% identity (57.5% similar) in 398 aa overlap (6-393:4-332) 10 20 30 40 50 60 pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ :::: .:::.:.::: ::::::::: .::... ....:. ..:::: : :.: : CCDS92 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP :::.::::: :.::.:.::.::. .::::..:.:.:.: . ::.:. CCDS92 PGCQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTV---RMQEKRKL------- 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK :.: :: .: :. :. : :: .: CCDS92 REAERA-----------------------------KEVRGS--GSYEYPVAEKAELSC-- 110 120 130 190 200 210 220 230 pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLYGFEV ..: :: .: :. .:: ... :...::.:.::::..::. . CCDS92 ----------------WEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFL 140 150 160 170 240 250 260 270 280 290 pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR . : :.:::: :.:.:::::::.::.. : .:. : :::.: :. ::: .: CCDS92 TTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLG----WKKIR 180 190 200 210 220 230 300 310 320 330 340 350 pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGL--AC--PPDYSLVVRAAERARAHDQNLANLAL : : . : : . . ..:. .: :::.. .. . .. . :.: CCDS92 QRFVKPRQHMAK------CQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMAS 240 250 260 270 280 360 370 380 390 400 410 pF1KB7 QALRDGAAAGD-RDRDSSPCVGLPAASRG--P--PRAGAPASRTGSATSAGTVGEQGRPG : :. .. . : ....: :. . : : : . .:. : CCDS92 QQNTDNLVTEQVRGQEQTPGEGFIQVRYGQKPEVPNGVSPGHRLPHGYHSDKRRLSKASS 290 300 310 320 330 340 420 430 pF1KB7 THERPGAKPRAGSEKGSASSRDGKTTVWI CCDS92 KARSDDLSV 350 >>CCDS432.1 GJA9 gene_id:81025|Hs108|chr1 (515 aa) initn: 743 init1: 404 opt: 434 Z-score: 315.7 bits: 67.8 E(32554): 2.9e-11 Smith-Waterman score: 667; 32.9% identity (60.6% similar) in 368 aa overlap (6-366:4-317) 10 20 30 40 50 60 pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ :..: :::.: :::..::.:::.: .::... .:..: ...:::. : :::.: CCDS43 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP ::: ::::: :.: .:.::.:.. .:.::..:.:.:..:: :. :.::.: CCDS43 PGCRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRL-RVLEEERQRM------- 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK .:.: ..: : : . ... :.: : .. .: CCDS43 ----KAQLR---------VELEEVEFEMPRDRRRLEQELCQLE-----------KRKLNK 120 130 140 190 200 210 220 230 240 pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVR : : : :. .:: .. .:.. ::.:..::::::::... CCDS43 A------------PL----------RGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLE 150 160 170 180 250 260 270 280 290 300 pF1KB7 PFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRG :.: : .:::...:::::::::::.::: : .. . :.::. :. :::. . . .. : CCDS43 PLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKRGLWG 190 200 210 220 230 240 310 320 330 340 350 pF1KB7 R---RGPPASAPAPAPRPPPCAFPAAAAG----LACPPDYSLVVRAAERARAHDQNLANL . . : . . ...:. : :::.:.:. .. .. . .. CCDS43 KYKLKKEHNEFHANKAKQNVAKYQSTSANSLKRLPSAPDYNLLVEKQTHTAVYPSLNSSS 250 260 270 280 290 300 360 370 380 390 400 410 pF1KB7 ALQALRDGAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHE ..: :. ...: CCDS43 VFQPNPDNHSVNDEKCILDEQETVLSNEISTLSTSCSHFQHISSNNNKDTHKIFGKELNG 310 320 330 340 350 360 >>CCDS10040.1 GJD2 gene_id:57369|Hs108|chr15 (321 aa) initn: 753 init1: 379 opt: 417 Z-score: 306.4 bits: 65.4 E(32554): 9.6e-11 Smith-Waterman score: 772; 42.1% identity (70.6% similar) in 299 aa overlap (6-300:4-286) 10 20 30 40 50 pF1KB7 MTNMSWSFLTRLLEE-IHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTR :..: :::: ...:::..:.. :::.:.:::...:. ::..:.:::. :.::: CCDS10 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTL 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 QPGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPG ::::...::: :.::.:.:::::... :::. .. :.::. :. ..::: . CCDS10 QPGCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAK--QRERRYSTVFLAL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 PRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGA-AEGAGEEAEEAGAEEAC : :: : : . : : :..:... .: ..:. ...:... : CCDS10 DRD------PPESIGGPGGTGGGGS----GGGKREDKKLQNAIVNGVLQNTENTSKE--- 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 TKAVGADGKAAGTPGPTGQHDGRR-RIQR-EGLMRVYVAQLVARAAFEVAFLVGQYLLYG :. . : :: :.: . . . ...: ::. : :. :.: : :.:..::::::.::: CCDS10 TEPDCLEVKEL-TPHPSGLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 FEVRPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQD : : .. :.: :: . :.:.:::::::::::. :..:: .:..::: :. ::: . . CCDS10 FSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 AVRGRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQ :::: CCDS10 AVRGAQAKRKSIYEIRNKDLPRVSVPNFGRTQSSDSAYV 290 300 310 320 439 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 19:55:09 2016 done: Mon Nov 7 19:55:09 2016 Total Scan time: 2.850 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]