Result of FASTA (omim) for
pF1KB7177
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7177, 482 aa
1>>>pF1KB7177 482 - 482 aa - 482 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7901+/-0.00039; mu= 8.8778+/- 0.024
mean_var=190.1599+/-38.718, 0's: 0 Z-trim(119.2): 137 B-trim: 462 in 1/55
Lambda= 0.093007
statistics sampled from 32844 (32984) to 32844 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.387), width: 16
Scan time: 8.940
The best scores are: opt bits E(85289)
NP_055971 (OMIM: 607675) REST corepressor 1 [Homo ( 485) 3141 433.8 5e-121
NP_775858 (OMIM: 616019) REST corepressor 2 [Homo ( 523) 1458 208.0 5.1e-53
XP_005273989 (OMIM: 616019) PREDICTED: REST corepr ( 477) 1187 171.6 4.2e-42
NP_001070729 (OMIM: 600848) nuclear receptor corep (2458) 327 56.9 7.5e-07
NP_001193583 (OMIM: 600848) nuclear receptor corep (2504) 327 56.9 7.6e-07
NP_006303 (OMIM: 600848) nuclear receptor corepres (2514) 327 56.9 7.6e-07
NP_001177367 (OMIM: 600849) nuclear receptor corep ( 914) 318 55.3 8.4e-07
NP_001177369 (OMIM: 600849) nuclear receptor corep (2337) 318 55.7 1.7e-06
XP_011522388 (OMIM: 600849) PREDICTED: nuclear rec (2337) 318 55.7 1.7e-06
NP_006302 (OMIM: 600849) nuclear receptor corepres (2440) 318 55.7 1.7e-06
XP_016880905 (OMIM: 600849) PREDICTED: nuclear rec (2456) 318 55.7 1.7e-06
XP_006721667 (OMIM: 600849) PREDICTED: nuclear rec (2456) 318 55.7 1.7e-06
XP_016880902 (OMIM: 600849) PREDICTED: nuclear rec (2514) 318 55.7 1.8e-06
XP_016880899 (OMIM: 600849) PREDICTED: nuclear rec (2514) 318 55.7 1.8e-06
XP_016880901 (OMIM: 600849) PREDICTED: nuclear rec (2514) 318 55.7 1.8e-06
XP_016880903 (OMIM: 600849) PREDICTED: nuclear rec (2514) 318 55.7 1.8e-06
XP_016880898 (OMIM: 600849) PREDICTED: nuclear rec (2514) 318 55.7 1.8e-06
XP_005256929 (OMIM: 600849) PREDICTED: nuclear rec (2514) 318 55.7 1.8e-06
XP_016880900 (OMIM: 600849) PREDICTED: nuclear rec (2514) 318 55.7 1.8e-06
XP_016880889 (OMIM: 600849) PREDICTED: nuclear rec (2523) 318 55.7 1.8e-06
XP_016880891 (OMIM: 600849) PREDICTED: nuclear rec (2523) 318 55.7 1.8e-06
XP_016880890 (OMIM: 600849) PREDICTED: nuclear rec (2523) 318 55.7 1.8e-06
XP_005256925 (OMIM: 600849) PREDICTED: nuclear rec (2523) 318 55.7 1.8e-06
XP_006721665 (OMIM: 600849) PREDICTED: nuclear rec (2523) 318 55.7 1.8e-06
XP_016880909 (OMIM: 600849) PREDICTED: nuclear rec (2331) 316 55.4 2e-06
XP_016880908 (OMIM: 600849) PREDICTED: nuclear rec (2347) 316 55.4 2e-06
XP_016880907 (OMIM: 600849) PREDICTED: nuclear rec (2404) 316 55.4 2.1e-06
XP_011522387 (OMIM: 600849) PREDICTED: nuclear rec (2405) 316 55.4 2.1e-06
XP_005256932 (OMIM: 600849) PREDICTED: nuclear rec (2448) 316 55.4 2.1e-06
XP_016880906 (OMIM: 600849) PREDICTED: nuclear rec (2450) 316 55.4 2.1e-06
XP_016880904 (OMIM: 600849) PREDICTED: nuclear rec (2465) 316 55.4 2.1e-06
XP_005256931 (OMIM: 600849) PREDICTED: nuclear rec (2466) 316 55.4 2.1e-06
XP_005256930 (OMIM: 600849) PREDICTED: nuclear rec (2508) 316 55.4 2.1e-06
XP_006721666 (OMIM: 600849) PREDICTED: nuclear rec (2511) 316 55.4 2.1e-06
XP_016880895 (OMIM: 600849) PREDICTED: nuclear rec (2515) 316 55.4 2.1e-06
XP_016880892 (OMIM: 600849) PREDICTED: nuclear rec (2515) 316 55.4 2.1e-06
XP_016880896 (OMIM: 600849) PREDICTED: nuclear rec (2515) 316 55.4 2.1e-06
XP_005256928 (OMIM: 600849) PREDICTED: nuclear rec (2515) 316 55.4 2.1e-06
XP_016880893 (OMIM: 600849) PREDICTED: nuclear rec (2515) 316 55.4 2.1e-06
XP_016880897 (OMIM: 600849) PREDICTED: nuclear rec (2515) 316 55.4 2.1e-06
XP_016880894 (OMIM: 600849) PREDICTED: nuclear rec (2515) 316 55.4 2.1e-06
XP_011522386 (OMIM: 600849) PREDICTED: nuclear rec (2523) 316 55.4 2.1e-06
XP_016880885 (OMIM: 600849) PREDICTED: nuclear rec (2524) 316 55.4 2.1e-06
XP_016880886 (OMIM: 600849) PREDICTED: nuclear rec (2524) 316 55.4 2.1e-06
XP_016880887 (OMIM: 600849) PREDICTED: nuclear rec (2524) 316 55.4 2.1e-06
XP_011522385 (OMIM: 600849) PREDICTED: nuclear rec (2524) 316 55.4 2.1e-06
XP_016880888 (OMIM: 600849) PREDICTED: nuclear rec (2524) 316 55.4 2.1e-06
XP_005256923 (OMIM: 600849) PREDICTED: nuclear rec (2524) 316 55.4 2.1e-06
XP_006721664 (OMIM: 600849) PREDICTED: nuclear rec (2524) 316 55.4 2.1e-06
>>NP_055971 (OMIM: 607675) REST corepressor 1 [Homo sapi (485 aa)
initn: 3141 init1: 3141 opt: 3141 Z-score: 2293.8 bits: 433.8 E(85289): 5e-121
Smith-Waterman score: 3141; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:4-485)
10 20 30 40 50
pF1KB7 MVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAAS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 AAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 AKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 SLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 HSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 ALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 KNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
430 440 450 460 470 480
480
pF1KB7 YASAS
:::::
NP_055 YASAS
>>NP_775858 (OMIM: 616019) REST corepressor 2 [Homo sapi (523 aa)
initn: 1309 init1: 726 opt: 1458 Z-score: 1072.9 bits: 208.0 E(85289): 5.1e-53
Smith-Waterman score: 1458; 54.3% identity (76.8% similar) in 435 aa overlap (57-476:3-425)
30 40 50 60 70 80
pF1KB7 ASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQ---NKSLAAAAPNGNSSSNS
:. :. :. ..: : ..:::.
NP_775 MPSVMEKPSAGSGILSRSRAKTVPNGG-----
10 20
90 100 110 120 130 140
pF1KB7 WEEGSSGSSSDEEHGGGGM-RVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLS
. : .::.:::. .: ::: .::::.:. : . :: :. .. ::::::::. .:
NP_775 -QPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSN-KELKGMLVWSPNHCVS
30 40 50 60 70 80
150 160 170 180 190 200
pF1KB7 EAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQ
.::::.:::.::::::::.:::::::.::::..::::::: :::::::::::::::::::
NP_775 DAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQ
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB7 AFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQK-REREESEDEL
::.:::: :.::::::::: : ::::.::::::::..::::::.::. :. .:. :::
NP_775 AFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDEL
150 160 170 180 190 200
270 280 290 300 310
pF1KB7 EEANGNNPIDIEVDQNKESKKEVP--PTETVPQV-KKEKHSTQAKN---RAKRKPPKGMF
::. :. . : : ... .: : .. : ::: . .: .. :..:.:::::.
NP_775 EEGRGGVS-EGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRHHPLRTRRRPPKGMY
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB7 LSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEV
:: : . :::.. :. .:: :: .:.:.:::.:..:::::.:.. :.:::.: : ::.
NP_775 LSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEA
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB7 IQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQ
: :.::::.::::::::::.::.:: ::..:::::...:::.:::.::::::..::::
NP_775 NTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQ
330 340 350 360 370 380
440 450 460 470 480
pF1KB7 EWEAEHGKEETNGPSNQKPVKSPDNSIKMP----EEEDEAPVLDVRYASAS
::::: . ..:. :.. . .: ::.::. . .:
NP_775 EWEAE----QDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPP
390 400 410 420 430 440
NP_775 PPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHS
450 460 470 480 490 500
>>XP_005273989 (OMIM: 616019) PREDICTED: REST corepresso (477 aa)
initn: 1144 init1: 709 opt: 1187 Z-score: 876.9 bits: 171.6 E(85289): 4.2e-42
Smith-Waterman score: 1187; 54.3% identity (75.8% similar) in 359 aa overlap (57-404:3-353)
30 40 50 60 70 80
pF1KB7 ASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQ---NKSLAAAAPNGNSSSNS
:. :. :. ..: : ..:::.
XP_005 MPSVMEKPSAGSGILSRSRAKTVPNGG-----
10 20
90 100 110 120 130 140
pF1KB7 WEEGSSGSSSDEEHGGGGM-RVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLS
. : .::.:::. .: ::: .::::.:. : . :: :. .. ::::::::. .:
XP_005 -QPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSN-KELKGMLVWSPNHCVS
30 40 50 60 70 80
150 160 170 180 190 200
pF1KB7 EAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQ
.::::.:::.::::::::.:::::::.::::..::::::: :::::::::::::::::::
XP_005 DAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQ
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB7 AFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQK-REREESEDEL
::.:::: :.::::::::: : ::::.::::::::..::::::.::. :. .:. :::
XP_005 AFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDEL
150 160 170 180 190 200
270 280 290 300 310
pF1KB7 EEANGNNPIDIEVDQNKESKKEVP--PTETVPQV-KKEKHSTQAKN---RAKRKPPKGMF
::. :. . : : ... .: : .. : ::: . .: .. :..:.:::::.
XP_005 EEGRGGVS-EGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRHHPLRTRRRPPKGMY
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB7 LSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEV
:: : . :::.. :. .:: :: .:.:.:::.:..:::::.:.. :.:::.: : ::.
XP_005 LSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEA
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB7 IQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQ
: :.::::.:::::::. : .:
XP_005 NTKFNSRWTTDEQLLAVQGPDYIGLHVRAPISAPCATTPSTSHLAVPATPAAEATFAHGS
330 340 350 360 370 380
>>NP_001070729 (OMIM: 600848) nuclear receptor corepress (2458 aa)
initn: 194 init1: 194 opt: 327 Z-score: 244.0 bits: 56.9 E(85289): 7.5e-07
Smith-Waterman score: 344; 25.6% identity (62.1% similar) in 285 aa overlap (192-470:431-702)
170 180 190 200 210 220
pF1KB7 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDK
:. ..: :.. : : :.: : ..: :
NP_001 ADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERK
410 420 430 440 450 460
230 240 250 260 270
pF1KB7 SIASLVKFYYSWKKTRTKTSVMDRHARK--QKREREESEDELEEANGNNPI---DIEVDQ
..: : .:: ::... :.. : :. ........... .. . ..:. . : .
NP_001 TVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKD
470 480 490 500 510 520
280 290 300 310 320 330
pF1KB7 NKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLR
.::..::. : :.:...:.. . : .: ..... : .. :: . :
NP_001 EKEKEKEAEKEEEKPEVENDKEDLL---KEKTDDTSGEDNDEKEAVASKGRKTANSQGRR
530 540 550 560 570
340 350 360 370 380 390
pF1KB7 QLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIR
. . :.. : ... :. . .. . ..: : ..::: ::. : ...
NP_001 KG-----RITRSMANEANSEEAITPQQSAELASMELNE-----SSRWTEEEMETAKKGLL
580 590 600 610 620
400 410 420 430 440 450
pF1KB7 KYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQK-PV
..::...::. ..:.:.: : :::. ::..: :.::.::. . . ::.. ...: :.
NP_001 EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA
630 640 650 660 670 680
460 470 480
pF1KB7 KSPDNSIKMPEEEDEAPVLDVRYASAS
. ... : :::
NP_001 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQN
690 700 710 720 730 740
>>NP_001193583 (OMIM: 600848) nuclear receptor corepress (2504 aa)
initn: 194 init1: 194 opt: 327 Z-score: 243.9 bits: 56.9 E(85289): 7.6e-07
Smith-Waterman score: 344; 25.6% identity (62.1% similar) in 285 aa overlap (192-470:431-702)
170 180 190 200 210 220
pF1KB7 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDK
:. ..: :.. : : :.: : ..: :
NP_001 ADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERK
410 420 430 440 450 460
230 240 250 260 270
pF1KB7 SIASLVKFYYSWKKTRTKTSVMDRHARK--QKREREESEDELEEANGNNPI---DIEVDQ
..: : .:: ::... :.. : :. ........... .. . ..:. . : .
NP_001 TVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKD
470 480 490 500 510 520
280 290 300 310 320 330
pF1KB7 NKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLR
.::..::. : :.:...:.. . : .: ..... : .. :: . :
NP_001 EKEKEKEAEKEEEKPEVENDKEDLL---KEKTDDTSGEDNDEKEAVASKGRKTANSQGRR
530 540 550 560 570
340 350 360 370 380 390
pF1KB7 QLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIR
. . :.. : ... :. . .. . ..: : ..::: ::. : ...
NP_001 KG-----RITRSMANEANSEEAITPQQSAELASMELNE-----SSRWTEEEMETAKKGLL
580 590 600 610 620
400 410 420 430 440 450
pF1KB7 KYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQK-PV
..::...::. ..:.:.: : :::. ::..: :.::.::. . . ::.. ...: :.
NP_001 EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA
630 640 650 660 670 680
460 470 480
pF1KB7 KSPDNSIKMPEEEDEAPVLDVRYASAS
. ... : :::
NP_001 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQN
690 700 710 720 730 740
>>NP_006303 (OMIM: 600848) nuclear receptor corepressor (2514 aa)
initn: 194 init1: 194 opt: 327 Z-score: 243.9 bits: 56.9 E(85289): 7.6e-07
Smith-Waterman score: 344; 25.6% identity (62.1% similar) in 285 aa overlap (192-470:432-703)
170 180 190 200 210 220
pF1KB7 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDK
:. ..: :.. : : :.: : ..: :
NP_006 ADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERK
410 420 430 440 450 460
230 240 250 260 270
pF1KB7 SIASLVKFYYSWKKTRTKTSVMDRHARK--QKREREESEDELEEANGNNPI---DIEVDQ
..: : .:: ::... :.. : :. ........... .. . ..:. . : .
NP_006 TVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKD
470 480 490 500 510 520
280 290 300 310 320 330
pF1KB7 NKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLR
.::..::. : :.:...:.. . : .: ..... : .. :: . :
NP_006 EKEKEKEAEKEEEKPEVENDKEDLL---KEKTDDTSGEDNDEKEAVASKGRKTANSQGRR
530 540 550 560 570
340 350 360 370 380 390
pF1KB7 QLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIR
. . :.. : ... :. . .. . ..: : ..::: ::. : ...
NP_006 KG-----RITRSMANEANSEEAITPQQSAELASMELNE-----SSRWTEEEMETAKKGLL
580 590 600 610 620
400 410 420 430 440 450
pF1KB7 KYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQK-PV
..::...::. ..:.:.: : :::. ::..: :.::.::. . . ::.. ...: :.
NP_006 EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA
630 640 650 660 670 680
460 470 480
pF1KB7 KSPDNSIKMPEEEDEAPVLDVRYASAS
. ... : :::
NP_006 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDT
690 700 710 720 730 740
>>NP_001177367 (OMIM: 600849) nuclear receptor corepress (914 aa)
initn: 271 init1: 184 opt: 318 Z-score: 243.1 bits: 55.3 E(85289): 8.4e-07
Smith-Waterman score: 318; 25.8% identity (57.4% similar) in 291 aa overlap (188-469:327-604)
160 170 180 190 200 210
pF1KB7 GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM
: . :: ..: .:.. : : :.: : ..
NP_001 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY
300 310 320 330 340 350
220 230 240 250 260 270
pF1KB7 LPDKSIASLVKFYYSWKKTRTKTSVMDRH-----ARKQKREREESEDELEEANGNNPIDI
: ::. . : .:: ::... ... :. .:.:. : .:...:: . ..
NP_001 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKT
360 370 380 390 400 410
280 290 300 310 320 330
pF1KB7 EVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAAT
: ...: ::. . : ::.... ... : : ..: .:. . .:.
NP_001 E--KKEEEKKD-------EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN
420 430 440 450 460
340 350 360 370 380 390
pF1KB7 TVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCN-ARWTTEEQLLA
. :. :. . . . .: :. . : : . . .::: ::. .:
NP_001 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVA
470 480 490 500 510 520
400 410 420 430 440 450
pF1KB7 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN
... ..::.. ::. ..:.:: .: :::. ::.:: :.:..::. : .. . : .
NP_001 KKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ----HKQKTSRKPRE
530 540 550 560 570 580
460 470 480
pF1KB7 QKPV---KSPDNSIKMPEEEDEAPVLDVRYASAS
.. : .: .... :.::
NP_001 ERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSED
590 600 610 620 630 640
>>NP_001177369 (OMIM: 600849) nuclear receptor corepress (2337 aa)
initn: 355 init1: 184 opt: 318 Z-score: 237.8 bits: 55.7 E(85289): 1.7e-06
Smith-Waterman score: 318; 25.8% identity (57.4% similar) in 291 aa overlap (188-469:436-713)
160 170 180 190 200 210
pF1KB7 GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM
: . :: ..: .:.. : : :.: : ..
NP_001 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY
410 420 430 440 450 460
220 230 240 250 260 270
pF1KB7 LPDKSIASLVKFYYSWKKTRTKTSVMDRH-----ARKQKREREESEDELEEANGNNPIDI
: ::. . : .:: ::... ... :. .:.:. : .:...:: . ..
NP_001 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKT
470 480 490 500 510 520
280 290 300 310 320 330
pF1KB7 EVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAAT
: ...: ::. . : ::.... ... : : ..: .:. . .:.
NP_001 E--KKEEEKKD-------EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN
530 540 550 560 570
340 350 360 370 380 390
pF1KB7 TVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCN-ARWTTEEQLLA
. :. :. . . . .: :. . : : . . .::: ::. .:
NP_001 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVA
580 590 600 610 620 630
400 410 420 430 440 450
pF1KB7 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN
... ..::.. ::. ..:.:: .: :::. ::.:: :.:..::. : .. . : .
NP_001 KKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ----HKQKTSRKPRE
640 650 660 670 680 690
460 470 480
pF1KB7 QKPV---KSPDNSIKMPEEEDEAPVLDVRYASAS
.. : .: .... :.::
NP_001 ERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSED
700 710 720 730 740 750
>>XP_011522388 (OMIM: 600849) PREDICTED: nuclear recepto (2337 aa)
initn: 355 init1: 184 opt: 318 Z-score: 237.8 bits: 55.7 E(85289): 1.7e-06
Smith-Waterman score: 318; 25.8% identity (57.4% similar) in 291 aa overlap (188-469:436-713)
160 170 180 190 200 210
pF1KB7 GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM
: . :: ..: .:.. : : :.: : ..
XP_011 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY
410 420 430 440 450 460
220 230 240 250 260 270
pF1KB7 LPDKSIASLVKFYYSWKKTRTKTSVMDRH-----ARKQKREREESEDELEEANGNNPIDI
: ::. . : .:: ::... ... :. .:.:. : .:...:: . ..
XP_011 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKT
470 480 490 500 510 520
280 290 300 310 320 330
pF1KB7 EVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAAT
: ...: ::. . : ::.... ... : : ..: .:. . .:.
XP_011 E--KKEEEKKD-------EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN
530 540 550 560 570
340 350 360 370 380 390
pF1KB7 TVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCN-ARWTTEEQLLA
. :. :. . . . .: :. . : : . . .::: ::. .:
XP_011 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVA
580 590 600 610 620 630
400 410 420 430 440 450
pF1KB7 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN
... ..::.. ::. ..:.:: .: :::. ::.:: :.:..::. : .. . : .
XP_011 KKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ----HKQKTSRKPRE
640 650 660 670 680 690
460 470 480
pF1KB7 QKPV---KSPDNSIKMPEEEDEAPVLDVRYASAS
.. : .: .... :.::
XP_011 ERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAVKPSED
700 710 720 730 740 750
>>NP_006302 (OMIM: 600849) nuclear receptor corepressor (2440 aa)
initn: 355 init1: 184 opt: 318 Z-score: 237.5 bits: 55.7 E(85289): 1.7e-06
Smith-Waterman score: 318; 25.8% identity (57.4% similar) in 291 aa overlap (188-469:436-713)
160 170 180 190 200 210
pF1KB7 GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQM
: . :: ..: .:.. : : :.: : ..
NP_006 MMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASY
410 420 430 440 450 460
220 230 240 250 260 270
pF1KB7 LPDKSIASLVKFYYSWKKTRTKTSVMDRH-----ARKQKREREESEDELEEANGNNPIDI
: ::. . : .:: ::... ... :. .:.:. : .:...:: . ..
NP_006 LERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKT
470 480 490 500 510 520
280 290 300 310 320 330
pF1KB7 EVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAAT
: ...: ::. . : ::.... ... : : ..: .:. . .:.
NP_006 E--KKEEEKKD-------EEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKTAN
530 540 550 560 570
340 350 360 370 380 390
pF1KB7 TVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCN-ARWTTEEQLLA
. :. :. . . . .: :. . : : . . .::: ::. .:
NP_006 SQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVA
580 590 600 610 620 630
400 410 420 430 440 450
pF1KB7 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN
... ..::.. ::. ..:.:: .: :::. ::.:: :.:..::. : .. . : .
NP_006 KKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ----HKQKTSRKPRE
640 650 660 670 680 690
460 470 480
pF1KB7 QKPV---KSPDNSIKMPEEEDEAPVLDVRYASAS
.. : .: .... :.::
NP_006 ERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVE
700 710 720 730 740 750
482 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:38:10 2016 done: Fri Nov 4 05:38:11 2016
Total Scan time: 8.940 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]