FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7180, 420 aa 1>>>pF1KB7180 420 - 420 aa - 420 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8346+/-0.000272; mu= 17.6790+/- 0.017 mean_var=128.1831+/-26.591, 0's: 0 Z-trim(122.6): 211 B-trim: 1939 in 1/56 Lambda= 0.113281 statistics sampled from 40636 (40896) to 40636 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.479), width: 16 Scan time: 10.500 The best scores are: opt bits E(85289) NP_079512 (OMIM: 607524) RING finger protein 39 is ( 420) 2951 493.0 6.1e-139 NP_739575 (OMIM: 607524) RING finger protein 39 is ( 354) 2267 381.1 2.4e-105 XP_016866815 (OMIM: 607524) PREDICTED: RING finger ( 230) 1584 269.3 7.3e-72 XP_016866814 (OMIM: 607524) PREDICTED: RING finger ( 267) 1574 267.7 2.5e-71 NP_976040 (OMIM: 609315) tripartite motif-containi ( 303) 274 55.3 2.5e-07 NP_976041 (OMIM: 609315) tripartite motif-containi ( 303) 274 55.3 2.5e-07 NP_976039 (OMIM: 609315) tripartite motif-containi ( 303) 274 55.3 2.5e-07 XP_016865392 (OMIM: 609315) PREDICTED: tripartite ( 303) 274 55.3 2.5e-07 NP_976042 (OMIM: 609315) tripartite motif-containi ( 329) 274 55.3 2.6e-07 NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 271 55.0 4.7e-07 NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 271 55.1 4.9e-07 NP_001185574 (OMIM: 607564) tripartite motif-conta ( 313) 248 51.1 4.8e-06 NP_001185573 (OMIM: 607564) tripartite motif-conta ( 313) 248 51.1 4.8e-06 XP_016866752 (OMIM: 600830) PREDICTED: tripartite ( 462) 244 50.6 9.7e-06 XP_011513161 (OMIM: 600830) PREDICTED: tripartite ( 462) 244 50.6 9.7e-06 XP_005249434 (OMIM: 600830) PREDICTED: tripartite ( 539) 244 50.7 1.1e-05 NP_001229712 (OMIM: 600830) tripartite motif-conta ( 539) 244 50.7 1.1e-05 XP_006715243 (OMIM: 600830) PREDICTED: tripartite ( 539) 244 50.7 1.1e-05 XP_005249432 (OMIM: 600830) PREDICTED: tripartite ( 539) 244 50.7 1.1e-05 XP_005249435 (OMIM: 600830) PREDICTED: tripartite ( 539) 244 50.7 1.1e-05 XP_005249431 (OMIM: 600830) PREDICTED: tripartite ( 539) 244 50.7 1.1e-05 XP_005249433 (OMIM: 600830) PREDICTED: tripartite ( 539) 244 50.7 1.1e-05 NP_003440 (OMIM: 600830) tripartite motif-containi ( 539) 244 50.7 1.1e-05 XP_016865393 (OMIM: 609315) PREDICTED: tripartite ( 221) 236 48.9 1.5e-05 NP_203128 (OMIM: 609315) tripartite motif-containi ( 221) 236 48.9 1.5e-05 XP_011542587 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 391) 236 49.2 2.2e-05 XP_016857901 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 467) 236 49.3 2.4e-05 NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 236 49.3 2.4e-05 NP_976038 (OMIM: 609315) tripartite motif-containi ( 511) 236 49.3 2.6e-05 NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 234 49.0 3.2e-05 NP_001008275 (OMIM: 613288) tripartite motif-conta ( 477) 232 48.7 3.9e-05 XP_011512533 (OMIM: 613591) PREDICTED: butyrophili ( 313) 226 47.5 5.8e-05 NP_001184168 (OMIM: 613591) butyrophilin subfamily ( 313) 226 47.5 5.8e-05 NP_001184162 (OMIM: 613590) butyrophilin subfamily ( 466) 227 47.8 6.7e-05 XP_005248855 (OMIM: 613591) PREDICTED: butyrophili ( 407) 226 47.6 6.9e-05 NP_853509 (OMIM: 613591) butyrophilin subfamily 2 ( 407) 226 47.6 6.9e-05 XP_016865656 (OMIM: 613591) PREDICTED: butyrophili ( 407) 226 47.6 6.9e-05 NP_008980 (OMIM: 613590) butyrophilin subfamily 2 ( 527) 227 47.9 7.3e-05 NP_291027 (OMIM: 610530) E3 ubiquitin-protein liga ( 630) 228 48.1 7.3e-05 XP_011512531 (OMIM: 613591) PREDICTED: butyrophili ( 461) 226 47.7 7.5e-05 XP_016865655 (OMIM: 613591) PREDICTED: butyrophili ( 461) 226 47.7 7.5e-05 NP_001184166 (OMIM: 613591) butyrophilin subfamily ( 523) 226 47.7 8.1e-05 XP_005248854 (OMIM: 613591) PREDICTED: butyrophili ( 523) 226 47.7 8.1e-05 XP_011512530 (OMIM: 613591) PREDICTED: butyrophili ( 523) 226 47.7 8.1e-05 XP_006715016 (OMIM: 613591) PREDICTED: butyrophili ( 523) 226 47.7 8.1e-05 NP_008926 (OMIM: 613591) butyrophilin subfamily 2 ( 523) 226 47.7 8.1e-05 NP_001723 (OMIM: 601610) butyrophilin subfamily 1 ( 526) 218 46.4 0.0002 XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626) 218 46.5 0.00023 XP_006714995 (OMIM: 610530) PREDICTED: E3 ubiquiti ( 520) 216 46.1 0.00025 XP_006714992 (OMIM: 610530) PREDICTED: E3 ubiquiti ( 543) 216 46.1 0.00026 >>NP_079512 (OMIM: 607524) RING finger protein 39 isofor (420 aa) initn: 2951 init1: 2951 opt: 2951 Z-score: 2615.5 bits: 493.0 E(85289): 6.1e-139 Smith-Waterman score: 2951; 100.0% identity (100.0% similar) in 420 aa overlap (1-420:1-420) 10 20 30 40 50 60 pF1KB7 MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 AASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GEDADDEESHYAVGAAGESVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPEPTLLGGVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 GEDADDEESHYAVGAAGESVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPEPTLLGGVEP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 PPRRIRVDLDWERGRVAFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 PPRRIRVDLDWERGRVAFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES 370 380 390 400 410 420 >>NP_739575 (OMIM: 607524) RING finger protein 39 isofor (354 aa) initn: 2467 init1: 2267 opt: 2267 Z-score: 2012.2 bits: 381.1 E(85289): 2.4e-105 Smith-Waterman score: 2339; 84.3% identity (84.3% similar) in 420 aa overlap (1-420:1-354) 10 20 30 40 50 60 pF1KB7 MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_739 MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_739 AASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_739 ATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_739 MGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_739 LLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 GEDADDEESHYAVGAAGESVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPEPTLLGGVEP ::::::::::::::::::::::::: NP_739 GEDADDEESHYAVGAAGESVQRKGC----------------------------------- 310 320 370 380 390 400 410 420 pF1KB7 PPRRIRVDLDWERGRVAFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES ::::::::::::::::::::::::::::: NP_739 -------------------------------APGPLGERIFPLFCTCDPRAPLRIVPAES 330 340 350 >>XP_016866815 (OMIM: 607524) PREDICTED: RING finger pro (230 aa) initn: 1584 init1: 1584 opt: 1584 Z-score: 1411.2 bits: 269.3 E(85289): 7.3e-72 Smith-Waterman score: 1584; 100.0% identity (100.0% similar) in 227 aa overlap (1-227:1-227) 10 20 30 40 50 60 pF1KB7 MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWWRDLTRLRLWLKREAIPGEGRKAAKVNAGVGEKGIYTASSRGGPPSARSKAVTVVAEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AASRSWLSMDAPELGPGLVERLEQLATCPLCGGSFEDPVLLACEHSFCRACLARRWGTPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATGTEASPTACPCCGLPCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 MGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRR ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTVAF 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 LLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSS >>XP_016866814 (OMIM: 607524) PREDICTED: RING finger pro (267 aa) initn: 1609 init1: 1571 opt: 1574 Z-score: 1401.6 bits: 267.7 E(85289): 2.5e-71 Smith-Waterman score: 1574; 90.6% identity (91.7% similar) in 254 aa overlap (167-420:22-267) 140 150 160 170 180 190 pF1KB7 PCPRRSLRSNVRLAVEVRISRELREKLAEPGARAGRRRGGRIPTMGCLDLPGEDMRKTWR : : .:: : . : . XP_016 MCGWRWRCESAASCERSWLSLGPVRGDAEGGASPPWAAWTCP--------E 10 20 30 40 200 210 220 230 240 250 pF1KB7 RFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPG 50 60 70 80 90 100 260 270 280 290 300 310 pF1KB7 TPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAA 110 120 130 140 150 160 320 330 340 350 360 370 pF1KB7 GESVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPEPTLLGGVEPPPRRIRVDLDWERGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GESVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPEPTLLGGVEPPPRRIRVDLDWERGRV 170 180 190 200 210 220 380 390 400 410 420 pF1KB7 AFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES :::::::::::::::::::::::::::::::::::::::::::: XP_016 AFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES 230 240 250 260 >>NP_976040 (OMIM: 609315) tripartite motif-containing p (303 aa) initn: 404 init1: 128 opt: 274 Z-score: 252.7 bits: 55.3 E(85289): 2.5e-07 Smith-Waterman score: 384; 39.8% identity (62.8% similar) in 191 aa overlap (229-417:135-303) 200 210 220 230 240 250 pF1KB7 EVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPGTP .::::: ::. ::..: : ..:.:. . NP_976 NVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQD 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB7 APPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAAGE : . : ::: ::.. ::..::: ::::... .:. .: :.: : NP_976 LP-NHPCRFDTNTRVLASCGFSSGRHHWEVEVGS----KDG-----------WAFGVARE 170 180 190 200 320 330 340 350 360 370 pF1KB7 SVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPE--PTLLGGVEPPPRRIRVDLDWERGRV ::.::: . . : .:::.. ::. ::.:.:: : : . :.:: :: : : : NP_976 SVRRKGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLS----RVRVALDLEVGAV 210 220 230 240 250 260 380 390 400 410 420 pF1KB7 AFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES .:: ... ::.:.. . ::.:::: .:. . ::: : NP_976 SFYAVEDMRHLYTFRVN--FQERVFPLFSVCSTGTYLRIWP 270 280 290 300 >>NP_976041 (OMIM: 609315) tripartite motif-containing p (303 aa) initn: 404 init1: 128 opt: 274 Z-score: 252.7 bits: 55.3 E(85289): 2.5e-07 Smith-Waterman score: 384; 39.8% identity (62.8% similar) in 191 aa overlap (229-417:135-303) 200 210 220 230 240 250 pF1KB7 EVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPGTP .::::: ::. ::..: : ..:.:. . NP_976 NVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQD 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB7 APPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAAGE : . : ::: ::.. ::..::: ::::... .:. .: :.: : NP_976 LP-NHPCRFDTNTRVLASCGFSSGRHHWEVEVGS----KDG-----------WAFGVARE 170 180 190 200 320 330 340 350 360 370 pF1KB7 SVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPE--PTLLGGVEPPPRRIRVDLDWERGRV ::.::: . . : .:::.. ::. ::.:.:: : : . :.:: :: : : : NP_976 SVRRKGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLS----RVRVALDLEVGAV 210 220 230 240 250 260 380 390 400 410 420 pF1KB7 AFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES .:: ... ::.:.. . ::.:::: .:. . ::: : NP_976 SFYAVEDMRHLYTFRVN--FQERVFPLFSVCSTGTYLRIWP 270 280 290 300 >>NP_976039 (OMIM: 609315) tripartite motif-containing p (303 aa) initn: 404 init1: 128 opt: 274 Z-score: 252.7 bits: 55.3 E(85289): 2.5e-07 Smith-Waterman score: 384; 39.8% identity (62.8% similar) in 191 aa overlap (229-417:135-303) 200 210 220 230 240 250 pF1KB7 EVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPGTP .::::: ::. ::..: : ..:.:. . NP_976 NVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQD 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB7 APPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAAGE : . : ::: ::.. ::..::: ::::... .:. .: :.: : NP_976 LP-NHPCRFDTNTRVLASCGFSSGRHHWEVEVGS----KDG-----------WAFGVARE 170 180 190 200 320 330 340 350 360 370 pF1KB7 SVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPE--PTLLGGVEPPPRRIRVDLDWERGRV ::.::: . . : .:::.. ::. ::.:.:: : : . :.:: :: : : : NP_976 SVRRKGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLS----RVRVALDLEVGAV 210 220 230 240 250 260 380 390 400 410 420 pF1KB7 AFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES .:: ... ::.:.. . ::.:::: .:. . ::: : NP_976 SFYAVEDMRHLYTFRVN--FQERVFPLFSVCSTGTYLRIWP 270 280 290 300 >>XP_016865392 (OMIM: 609315) PREDICTED: tripartite moti (303 aa) initn: 404 init1: 128 opt: 274 Z-score: 252.7 bits: 55.3 E(85289): 2.5e-07 Smith-Waterman score: 384; 39.8% identity (62.8% similar) in 191 aa overlap (229-417:135-303) 200 210 220 230 240 250 pF1KB7 EVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPGTP .::::: ::. ::..: : ..:.:. . XP_016 NVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQD 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB7 APPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAAGE : . : ::: ::.. ::..::: ::::... .:. .: :.: : XP_016 LP-NHPCRFDTNTRVLASCGFSSGRHHWEVEVGS----KDG-----------WAFGVARE 170 180 190 200 320 330 340 350 360 370 pF1KB7 SVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPE--PTLLGGVEPPPRRIRVDLDWERGRV ::.::: . . : .:::.. ::. ::.:.:: : : . :.:: :: : : : XP_016 SVRRKGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLS----RVRVALDLEVGAV 210 220 230 240 250 260 380 390 400 410 420 pF1KB7 AFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES .:: ... ::.:.. . ::.:::: .:. . ::: : XP_016 SFYAVEDMRHLYTFRVN--FQERVFPLFSVCSTGTYLRIWP 270 280 290 300 >>NP_976042 (OMIM: 609315) tripartite motif-containing p (329 aa) initn: 404 init1: 128 opt: 274 Z-score: 252.3 bits: 55.3 E(85289): 2.6e-07 Smith-Waterman score: 384; 39.8% identity (62.8% similar) in 191 aa overlap (229-417:161-329) 200 210 220 230 240 250 pF1KB7 EVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRRLLISADRRSVQLAPPGTP .::::: ::. ::..: : ..:.:. . NP_976 NVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQD 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB7 APPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSSGEDADDEESHYAVGAAGE : . : ::: ::.. ::..::: ::::... .:. .: :.: : NP_976 LP-NHPCRFDTNTRVLASCGFSSGRHHWEVEVGS----KDG-----------WAFGVARE 200 210 220 230 320 330 340 350 360 370 pF1KB7 SVQRKGCVRLCPAGAVWAVEGRGGRLWALTAPE--PTLLGGVEPPPRRIRVDLDWERGRV ::.::: . . : .:::.. ::. ::.:.:: : : . :.:: :: : : : NP_976 SVRRKGLTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLS----RVRVALDLEVGAV 240 250 260 270 280 290 380 390 400 410 420 pF1KB7 AFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAES .:: ... ::.:.. . ::.:::: .:. . ::: : NP_976 SFYAVEDMRHLYTFRVN--FQERVFPLFSVCSTGTYLRIWP 300 310 320 >>NP_742013 (OMIM: 605700) E3 ubiquitin-protein ligase T (488 aa) initn: 399 init1: 219 opt: 271 Z-score: 247.6 bits: 55.0 E(85289): 4.7e-07 Smith-Waterman score: 379; 35.4% identity (62.1% similar) in 195 aa overlap (211-404:290-465) 190 200 210 220 230 240 pF1KB7 MGCLDLPGEDMRKTWRRFEVPTSKSSNSEDDLPEDYPVVKKMLHRLTADLTLDPGTAHRR ..:..: ...:.:..: ::.:::: ::: NP_742 KDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPN 260 270 280 290 300 310 250 260 270 280 290 300 pF1KB7 LLISADRRSVQLAPPGTPAPPDGPKRFDQLPAVLGAQGFGAGRHCWEVETADAASCRDSS :..: ::.::... :: :.:: : ::...:: .::: ::::..: NP_742 LVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGD-------- 320 330 340 350 360 370 310 320 330 340 350 pF1KB7 GEDADDEESHYAVGAAGESVQRKGCVRLCPAGAVWAVE-GRGGRLWALTAPEPTLLGGVE ..:.:::. .::.::: . : . : :. : . : :.: : .. NP_742 -------KTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPL--HIK 380 390 400 410 420 360 370 380 390 400 410 pF1KB7 PPPRRIRVDLDWERGRVAFYDGRSLDLLYAFQAPGPLGERIFPLFCTCDPRAPLRIVPAE :.:. . ::.: : ..::. . . .:.: . :...::: NP_742 VKPKRVGIFLDYEAGTLSFYNVTDRSHIYTF--TDTFTEKLWPLFYPGIRAGRKNAAPLT 430 440 450 460 470 480 420 pF1KB7 S NP_742 IRPPTDWE 420 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:39:22 2016 done: Fri Nov 4 05:39:23 2016 Total Scan time: 10.500 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]