FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7184, 221 aa 1>>>pF1KB7184 221 - 221 aa - 221 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4651+/-0.000724; mu= 12.4916+/- 0.044 mean_var=61.3416+/-12.185, 0's: 0 Z-trim(109.1): 21 B-trim: 5 in 1/51 Lambda= 0.163756 statistics sampled from 10633 (10648) to 10633 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.327), width: 16 Scan time: 2.180 The best scores are: opt bits E(32554) CCDS4652.1 GPX5 gene_id:2880|Hs108|chr6 ( 221) 1517 366.5 7.5e-102 CCDS43389.1 GPX3 gene_id:2878|Hs108|chr5 ( 226) 1082 263.7 6.6e-71 CCDS43432.1 GPX6 gene_id:257202|Hs108|chr6 ( 221) 1046 255.2 2.4e-68 CCDS43091.1 GPX1 gene_id:2876|Hs108|chr3 ( 203) 597 149.1 1.9e-36 CCDS4653.1 GPX5 gene_id:2880|Hs108|chr6 ( 100) 545 136.7 5e-33 CCDS41964.1 GPX2 gene_id:2877|Hs108|chr14 ( 190) 540 135.7 2e-32 CCDS569.1 GPX7 gene_id:2882|Hs108|chr1 ( 187) 283 74.9 3.7e-14 >>CCDS4652.1 GPX5 gene_id:2880|Hs108|chr6 (221 aa) initn: 1517 init1: 1517 opt: 1517 Z-score: 1942.0 bits: 366.5 E(32554): 7.5e-102 Smith-Waterman score: 1517; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221) 10 20 30 40 50 60 pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR 130 140 150 160 170 180 190 200 210 220 pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK ::::::::::::::::::::::::::::::::::::::::: CCDS46 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK 190 200 210 220 >>CCDS43389.1 GPX3 gene_id:2878|Hs108|chr5 (226 aa) initn: 1077 init1: 1077 opt: 1082 Z-score: 1386.4 bits: 263.7 E(32554): 6.6e-71 Smith-Waterman score: 1082; 70.5% identity (87.1% similar) in 217 aa overlap (1-217:1-217) 10 20 30 40 50 60 pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV :. :.. :: :::: ::. : ::: ::::: .::::.: :.... .::. ::::. CCDS43 MARLLQASCLLSLLLAGFVSQSRGQEKSKMDCHGGISGTIYEYGALTIDGEEYIPFKQYA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK ::..::::::.:::::.:: ::::::::: :.:::.::::::::::::::.:.:::: :: CCDS43 GKYVLFVNVASYCGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGENSEILPTLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR ::::::::::.:::::::::::::::: ..:::.::: ::.::: . :.:.:::::: CCDS43 YVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWEPMKVHDIR 130 140 150 160 170 180 190 200 210 220 pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK ::::::::::::::.::: ::.:::.:: :::.:... CCDS43 WNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK 190 200 210 220 >>CCDS43432.1 GPX6 gene_id:257202|Hs108|chr6 (221 aa) initn: 1028 init1: 1008 opt: 1046 Z-score: 1340.6 bits: 255.2 E(32554): 2.4e-68 Smith-Waterman score: 1046; 67.3% identity (88.2% similar) in 220 aa overlap (1-220:1-220) 10 20 30 40 50 60 pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV : :... :. ..:. :.: . : .. :.::.: ::::.: :..:: .::..:::.. CCDS43 MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK :::.::::::.::::.:::::::::::::: .:..::.:::::::::::: :.::: ::: CCDS43 GKHVLFVNVAAYCGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR :: ::.:::::::::::::::::::::::.:::.::: :..::. ... :.:.:::::: CCDS43 YVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIR 130 140 150 160 170 180 190 200 210 220 pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK ::::::::::::.:::.: :.: ::.::.::: :::::.: CCDS43 WNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH 190 200 210 220 >>CCDS43091.1 GPX1 gene_id:2876|Hs108|chr3 (203 aa) initn: 561 init1: 350 opt: 597 Z-score: 767.9 bits: 149.1 E(32554): 1.9e-36 Smith-Waterman score: 597; 50.0% identity (73.9% similar) in 184 aa overlap (39-217:15-198) 10 20 30 40 50 60 pF1KB7 HLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVN ..: . : : .: ::. . :: .:. : CCDS43 MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIEN 10 20 30 40 70 80 90 100 110 120 pF1KB7 VATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGG ::. :: :.. : ..: ::..: : :::::::::::::.:: . :.::: .::::::::: CCDS43 VASLCGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 FVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSE----ILGTFKSISWDPVKVHDIRWNF : :.:.:::: .::: . .:.::... : ::. .. : :.:.:: .:. ::: CCDS43 FEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNF 110 120 130 140 150 160 190 200 210 220 pF1KB7 EKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK :::::::::.:. :.:.: . ... :: : :.: CCDS43 EKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA 170 180 190 200 >>CCDS4653.1 GPX5 gene_id:2880|Hs108|chr6 (100 aa) initn: 560 init1: 545 opt: 545 Z-score: 706.5 bits: 136.7 E(32554): 5e-33 Smith-Waterman score: 545; 92.1% identity (96.6% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK :::::::::::::::::::: ... :.: CCDS46 GKHILFVNVATYCGLTAQYPGMSVQGEDLYLVSSFLRKGM 70 80 90 100 >>CCDS41964.1 GPX2 gene_id:2877|Hs108|chr14 (190 aa) initn: 482 init1: 313 opt: 540 Z-score: 695.6 bits: 135.7 E(32554): 2e-32 Smith-Waterman score: 540; 46.4% identity (72.1% similar) in 183 aa overlap (39-216:7-187) 10 20 30 40 50 60 pF1KB7 HLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVN ..:: ::.:. .: :.:. . :. .:. : CCDS41 MAFIAKSFYDLSAISLD-GEKVDFNTFRGRAVLIEN 10 20 30 70 80 90 100 110 120 pF1KB7 VATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGG ::. :: :.. . .:: :: .. : ::::::::::::.:: .:.::: .::::::::: CCDS41 VASLCGTTTRDFTQLNELQCRF-PRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGG 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 FVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSE----ILGTFKSISWDPVKVHDIRWNF . :.: : .: .:::..:. ::..:: . :.: . .. : : :.::. :. ::: CCDS41 YQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNF 100 110 120 130 140 150 190 200 210 220 pF1KB7 EKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK ::::.::.: : :.:. . ... :: :: CCDS41 EKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI 160 170 180 190 >>CCDS569.1 GPX7 gene_id:2882|Hs108|chr1 (187 aa) initn: 212 init1: 153 opt: 283 Z-score: 367.6 bits: 74.9 E(32554): 3.7e-14 Smith-Waterman score: 327; 34.6% identity (61.7% similar) in 188 aa overlap (32-218:18-179) 10 20 30 40 50 60 pF1KB7 TTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVG : ..:. .::..:. . ... ::...: : CCDS56 MVAATVAAAWLLLWAAACAQQEQD-FYDFKAVNI-RGKLVSLEKYRG 10 20 30 40 70 80 90 100 110 120 pF1KB7 KHILFVNVATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK . : ::::. ::.: : : :. ::..: :. . ::.:::::::.::: .:::: . CCDS56 SVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEI---ES 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR ..: . :: .: : :.: . .:..: .. . .:. CCDS56 FARR--TYSVSFPMFSKIAVTGTGAHPAFKYLAQTSGK-------------EPT------ 110 120 130 140 190 200 210 220 pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK ::: :.::.::: : :. ..: :. .: : .... CCDS56 WNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLILLKREDL 150 160 170 180 221 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:40:29 2016 done: Fri Nov 4 05:40:30 2016 Total Scan time: 2.180 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]