FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7186, 437 aa 1>>>pF1KB7186 437 - 437 aa - 437 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6453+/-0.000317; mu= 13.0853+/- 0.020 mean_var=129.8534+/-25.879, 0's: 0 Z-trim(120.5): 18 B-trim: 718 in 1/58 Lambda= 0.112551 statistics sampled from 35835 (35853) to 35835 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.42), width: 16 Scan time: 10.310 The best scores are: opt bits E(85289) NP_003107 (OMIM: 603038) sperm-associated antigen ( 437) 2951 490.1 4.7e-138 XP_011527311 (OMIM: 603038) PREDICTED: sperm-assoc ( 393) 2274 380.1 5.4e-105 XP_005260577 (OMIM: 603038) PREDICTED: sperm-assoc ( 344) 2254 376.8 4.6e-104 NP_001304860 (OMIM: 603038) sperm-associated antig ( 360) 2252 376.5 6e-104 NP_542406 (OMIM: 613942) SUN domain-containing pro ( 379) 770 135.9 1.7e-31 XP_011526877 (OMIM: 613942) PREDICTED: SUN domain- ( 289) 762 134.5 3.4e-31 XP_011526876 (OMIM: 613942) PREDICTED: SUN domain- ( 354) 763 134.8 3.6e-31 XP_011526875 (OMIM: 613942) PREDICTED: SUN domain- ( 402) 763 134.8 3.9e-31 XP_011528406 (OMIM: 613569) PREDICTED: SUN domain- ( 671) 543 99.3 3.3e-20 XP_011528407 (OMIM: 613569) PREDICTED: SUN domain- ( 706) 543 99.3 3.4e-20 NP_056189 (OMIM: 613569) SUN domain-containing pro ( 717) 543 99.3 3.4e-20 NP_001186509 (OMIM: 613569) SUN domain-containing ( 717) 543 99.3 3.4e-20 NP_001186508 (OMIM: 613569) SUN domain-containing ( 738) 543 99.3 3.5e-20 NP_001165415 (OMIM: 607723) SUN domain-containing ( 682) 490 90.7 1.3e-17 NP_079430 (OMIM: 607723) SUN domain-containing pro ( 702) 490 90.7 1.3e-17 NP_001124437 (OMIM: 607723) SUN domain-containing ( 785) 490 90.7 1.4e-17 XP_016884237 (OMIM: 613569) PREDICTED: SUN domain- ( 683) 410 77.7 1.1e-13 >>NP_003107 (OMIM: 603038) sperm-associated antigen 4 pr (437 aa) initn: 2951 init1: 2951 opt: 2951 Z-score: 2599.5 bits: 490.1 E(85289): 4.7e-138 Smith-Waterman score: 2951; 100.0% identity (100.0% similar) in 437 aa overlap (1-437:1-437) 10 20 30 40 50 60 pF1KB7 MRRSSRPGSASSSRKHTPNFFSENSSMSITSEDSKGLRSAEPGPGEPEGRRARGPSCGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MRRSSRPGSASSSRKHTPNFFSENSSMSITSEDSKGLRSAEPGPGEPEGRRARGPSCGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ALSAGVPGGTTWAGSSQQKPAPRSHNWQTACGAATVRGGASEPTGSPVVSEEPLDLLPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ALSAGVPGGTTWAGSSQQKPAPRSHNWQTACGAATVRGGASEPTGSPVVSEEPLDLLPTL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 DLRQEMPPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DLRQEMPPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 FWLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FWLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSER 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 VAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 LQVYDETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LQVYDETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRA 370 380 390 400 410 420 430 pF1KB7 HGVRTSEGAEGSAQGPH ::::::::::::::::: NP_003 HGVRTSEGAEGSAQGPH 430 >>XP_011527311 (OMIM: 603038) PREDICTED: sperm-associate (393 aa) initn: 2267 init1: 2267 opt: 2274 Z-score: 2006.0 bits: 380.1 E(85289): 5.4e-105 Smith-Waterman score: 2542; 89.9% identity (89.9% similar) in 437 aa overlap (1-437:1-393) 10 20 30 40 50 60 pF1KB7 MRRSSRPGSASSSRKHTPNFFSENSSMSITSEDSKGLRSAEPGPGEPEGRRARGPSCGEP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRRSSRPGSASSSRKHTPNFFSENSSMSITSEDSKGLRSAEPGPGEPEGRRARGPSC--- 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 ALSAGVPGGTTWAGSSQQKPAPRSHNWQTACGAATVRGGASEPTGSPVVSEEPLDLLPTL ::::::::::::::::::: XP_011 -----------------------------------------EPTGSPVVSEEPLDLLPTL 60 70 130 140 150 160 170 180 pF1KB7 DLRQEMPPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLRQEMPPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSA 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB7 FWLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FWLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSER 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB7 VAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTV 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB7 ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFG 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB7 LQVYDETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQVYDETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRA 320 330 340 350 360 370 430 pF1KB7 HGVRTSEGAEGSAQGPH ::::::::::::::::: XP_011 HGVRTSEGAEGSAQGPH 380 390 >>XP_005260577 (OMIM: 603038) PREDICTED: sperm-associate (344 aa) initn: 2254 init1: 2254 opt: 2254 Z-score: 1989.2 bits: 376.8 E(85289): 4.6e-104 Smith-Waterman score: 2254; 100.0% identity (100.0% similar) in 336 aa overlap (102-437:9-344) 80 90 100 110 120 130 pF1KB7 WAGSSQQKPAPRSHNWQTACGAATVRGGASEPTGSPVVSEEPLDLLPTLDLRQEMPPPRV :::::::::::::::::::::::::::::: XP_005 MISGHLLQEPTGSPVVSEEPLDLLPTLDLRQEMPPPRV 10 20 30 140 150 160 170 180 190 pF1KB7 FKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSAFWLGLLYLVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSAFWLGLLYLVSP 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB7 LENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSERVAKLVFQRLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSERVAKLVFQRLNE 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB7 DFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHVFPGNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHVFPGNC 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB7 WAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQVYDETEVSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQVYDETEVSL 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB7 GKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTSEGAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTSEGAEG 280 290 300 310 320 330 pF1KB7 SAQGPH :::::: XP_005 SAQGPH 340 >>NP_001304860 (OMIM: 603038) sperm-associated antigen 4 (360 aa) initn: 2251 init1: 2251 opt: 2252 Z-score: 1987.2 bits: 376.5 E(85289): 6e-104 Smith-Waterman score: 2252; 98.8% identity (99.4% similar) in 341 aa overlap (97-437:22-360) 70 80 90 100 110 120 pF1KB7 PGGTTWAGSSQQKPAPRSHNWQTACGAATVRGGASEPTGSPVVSEEPLDLLPTLDLRQEM :: ..:::::::::::::::::::::::: NP_001 MGRKLSAEASASEPQLADSLWRG--NQPTGSPVVSEEPLDLLPTLDLRQEM 10 20 30 40 130 140 150 160 170 180 pF1KB7 PPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSAFWLGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSAFWLGLL 50 60 70 80 90 100 190 200 210 220 230 240 pF1KB7 YLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSERVAKLVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSERVAKLVF 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB7 QRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHV 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB7 FPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQVYDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQVYDE 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB7 TEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTS 290 300 310 320 330 340 430 pF1KB7 EGAEGSAQGPH ::::::::::: NP_001 EGAEGSAQGPH 350 360 >>NP_542406 (OMIM: 613942) SUN domain-containing protein (379 aa) initn: 657 init1: 479 opt: 770 Z-score: 686.4 bits: 135.9 E(85289): 1.7e-31 Smith-Waterman score: 770; 37.1% identity (64.9% similar) in 385 aa overlap (63-437:7-375) 40 50 60 70 80 90 pF1KB7 DSKGLRSAEPGPGEPEGRRARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQTACG : : ::. . ..: :: . : NP_542 MPRSSRSPGDPGALL--EDVAHNPRPRRIAQR---G 10 20 30 100 110 120 130 140 150 pF1KB7 AATVRGGASEPTGSPVVSEEPLDLLPTLDLRQEMPPPRVFKSFLSLLFQGLSVLLSLAGD : : .: : :: .... : ::. . : . . . . .: . : . : . NP_542 RNTSR--MAEDT-SPNMNDNIL--LPVRNNDQALGLTQCMLGCVSWFTCFACSLRTQAQQ 40 50 60 70 80 160 170 180 190 200 pF1KB7 VLVSMYRE--VCSIRFLFTAVSLLSLFLSAFWLGLLYLVSPLE-------NEPKEMLTLS :: . : .:. . :.. :: : .::. ..: : .. : : . : : NP_542 VLFNTCRCKLLCQKLMEKTGILLLCAF--GFWMFSIHLPSKMKVWQDDSINGPLQSLRL- 90 100 110 120 130 140 210 220 230 240 250 260 pF1KB7 EYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSE-RVAKLVFQRLNEDFVRKPDYALS :.:.:: .. ..:.:.. ...: ... ..: ..: ..:. ... .. :...:::.::. NP_542 -YQEKVRHHSGEIQDLRGSMNQLIAKLQEMEAMSDEQKMAQKIMKMIHGDYIEKPDFALK 150 160 170 180 190 200 270 280 290 300 310 320 pF1KB7 SVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHVFPGNCWAFEGDQGQVV :.:::::...:: : ... .:: ...::::.:: :::::.: ::::::::::.:::. NP_542 SIGASIDFEHTSVTYNHEKAHSYWNWIQLWNYAQPPDVILEPNVTPGNCWAFEGDRGQVT 210 220 230 240 250 260 330 340 350 360 370 380 pF1KB7 IQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQVYDETEVSLGKFTFDVEKSE ::: .: ::..:::: : .. .:. ..::.::...:.. . :: :: : :. :. NP_542 IQLAQKVYLSNLTLQHIPKTISLSGSLDTAPKDFVIYGMEGSPKEEVFLGAFQFQPENI- 270 280 290 300 310 320 390 400 410 420 430 pF1KB7 IQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTSEGAEGSAQGPH :: : :::.: :: ::..: ::::.: ::::::::.:: .. : :.:. NP_542 IQMFPLQNQPARAFSAVKVKISSNWGNPGFTCLYRVRVHG-SVAPPREQPHQNPYPKRD 330 340 350 360 370 >>XP_011526877 (OMIM: 613942) PREDICTED: SUN domain-cont (289 aa) initn: 657 init1: 479 opt: 762 Z-score: 680.9 bits: 134.5 E(85289): 3.4e-31 Smith-Waterman score: 762; 41.8% identity (71.9% similar) in 285 aa overlap (161-437:7-285) 140 150 160 170 180 190 pF1KB7 VFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSAFWLGLLYLVS .:. . :.. :: : .::. ..: : XP_011 MCVCKLLCQKLMEKTGILLLCAF--GFWMFSIHLPS 10 20 30 200 210 220 230 240 pF1KB7 PLE-------NEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSE-RVA .. : : . : : :.:.:: .. ..:.:.. ...: ... ..: ..: ..: XP_011 KMKVWQDDSINGPLQSLRL--YQEKVRHHSGEIQDLRGSMNQLIAKLQEMEAMSDEQKMA 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB7 KLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVIL . ... .. :...:::.::.:.:::::...:: : ... .:: ...::::.:: ::: XP_011 QKIMKMIHGDYIEKPDFALKSIGASIDFEHTSVTYNHEKAHSYWNWIQLWNYAQPPDVIL 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB7 EPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQ ::.: ::::::::::.:::.::: .: ::..:::: : .. .:. ..::.::...:.. XP_011 EPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKTISLSGSLDTAPKDFVIYGME 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB7 VYDETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHG . :: :: : :. :. :: : :::.: :: ::..: ::::.: ::::::::.:: XP_011 GSPKEEVFLGAFQFQPENI-IQMFPLQNQPARAFSAVKVKISSNWGNPGFTCLYRVRVHG 220 230 240 250 260 270 430 pF1KB7 VRTSEGAEGSAQGPH .. : :.:. XP_011 -SVAPPREQPHQNPYPKRD 280 >>XP_011526876 (OMIM: 613942) PREDICTED: SUN domain-cont (354 aa) initn: 657 init1: 479 opt: 763 Z-score: 680.6 bits: 134.8 E(85289): 3.6e-31 Smith-Waterman score: 763; 41.1% identity (70.5% similar) in 302 aa overlap (146-437:55-350) 120 130 140 150 160 170 pF1KB7 LLPTLDLRQEMPPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYRE--VCSIRFLFTAVSL : . : .:: . : .:. . :.. : XP_011 RRIAQRGRNTSRMAEDTSPNMTWFTCFACSLRTQAQQVLFNTCRCKLLCQKLMEKTGILL 30 40 50 60 70 80 180 190 200 210 220 pF1KB7 LSLFLSAFWLGLLYLVSPLE-------NEPKEMLTLSEYHERVRSQGQQLQQLQAELDKL : : .::. ..: : .. : : . : : :.:.:: .. ..:.:.. ...: XP_011 LCAF--GFWMFSIHLPSKMKVWQDDSINGPLQSLRL--YQEKVRHHSGEIQDLRGSMNQL 90 100 110 120 130 140 230 240 250 260 270 280 pF1KB7 HKEVSTVRAANSE-RVAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYF ... ..: ..: ..:. ... .. :...:::.::.:.:::::...:: : ... . XP_011 IAKLQEMEAMSDEQKMAQKIMKMIHGDYIEKPDFALKSIGASIDFEHTSVTYNHEKAHSY 150 160 170 180 190 200 290 300 310 320 330 340 pF1KB7 WNRFSFWNYARPPTVILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEH :: ...::::.:: :::::.: ::::::::::.:::.::: .: ::..:::: : .. XP_011 WNWIQLWNYAQPPDVILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKTISL 210 220 230 240 250 260 350 360 370 380 390 400 pF1KB7 TGGANSAPRDFAVFGLQVYDETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILS .:. ..::.::...:.. . :: :: : :. : . :: : :::.: :: ::..: : XP_011 SGSLDTAPKDFVIYGMEGSPKEEVFLGAFQFQPE-NIIQMFPLQNQPARAFSAVKVKISS 270 280 290 300 310 410 420 430 pF1KB7 NWGHPRFTCLYRVRAHGVRTSEGAEGSAQGPH :::.: ::::::::.:: .. : :.:. XP_011 NWGNPGFTCLYRVRVHG-SVAPPREQPHQNPYPKRD 320 330 340 350 >>XP_011526875 (OMIM: 613942) PREDICTED: SUN domain-cont (402 aa) initn: 657 init1: 479 opt: 763 Z-score: 679.9 bits: 134.8 E(85289): 3.9e-31 Smith-Waterman score: 764; 39.3% identity (67.7% similar) in 331 aa overlap (122-437:74-398) 100 110 120 130 140 pF1KB7 GAATVRGGASEPTGSPVVSEEPLDLLPTLDLRQEMPPPRVFKS-----FLSLLFQGLSVL : . . :: : : :.. . : XP_011 NMNDNILLPVRNNDQALGLTQCMLGCVFWLLVSPIHPPVEFISSPRPYFIAWFTCFACSL 50 60 70 80 90 100 150 160 170 180 190 pF1KB7 LSLAGDVLVSMYRE--VCSIRFLFTAVSLLSLFLSAFWLGLLYLVSPLE-------NEPK . : .:: . : .:. . :.. :: : .::. ..: : .. : : XP_011 RTQAQQVLFNTCRCKLLCQKLMEKTGILLLCAF--GFWMFSIHLPSKMKVWQDDSINGPL 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB7 EMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSE-RVAKLVFQRLNEDFVRK . : : :.:.:: .. ..:.:.. ...: ... ..: ..: ..:. ... .. :...: XP_011 QSLRL--YQEKVRHHSGEIQDLRGSMNQLIAKLQEMEAMSDEQKMAQKIMKMIHGDYIEK 170 180 190 200 210 260 270 280 290 300 310 pF1KB7 PDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHVFPGNCWAFEG ::.::.:.:::::...:: : ... .:: ...::::.:: :::::.: ::::::::: XP_011 PDFALKSIGASIDFEHTSVTYNHEKAHSYWNWIQLWNYAQPPDVILEPNVTPGNCWAFEG 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB7 DQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQVYDETEVSLGKFTF :.:::.::: .: ::..:::: : .. .:. ..::.::...:.. . :: :: : : XP_011 DRGQVTIQLAQKVYLSNLTLQHIPKTISLSGSLDTAPKDFVIYGMEGSPKEEVFLGAFQF 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB7 DVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTSEGAEGSAQGP . : . :: : :::.: :: ::..: ::::.: ::::::::.:: .. : :.: XP_011 QPE-NIIQMFPLQNQPARAFSAVKVKISSNWGNPGFTCLYRVRVHG-SVAPPREQPHQNP 340 350 360 370 380 390 pF1KB7 H . XP_011 YPKRD 400 >>XP_011528406 (OMIM: 613569) PREDICTED: SUN domain-cont (671 aa) initn: 520 init1: 319 opt: 543 Z-score: 483.8 bits: 99.3 E(85289): 3.3e-20 Smith-Waterman score: 543; 39.7% identity (68.2% similar) in 214 aa overlap (212-422:454-667) 190 200 210 220 230 pF1KB7 WLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELD-KLHKE-VSTVRAANSE ::.. .. : :. :.:: : : . . XP_011 GGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVH 430 440 450 460 470 480 240 250 260 270 280 290 pF1KB7 RVAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPT ...: ..:: .:: . :::: : :::. . :. : ... . .: ... : XP_011 HIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPR 490 500 510 520 530 540 300 310 320 330 340 350 pF1KB7 VILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVF :::.: : :::::::.: :: .:..: .:.. . .::.: : .. .. .:::.:::.: XP_011 VILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIF 550 560 570 580 590 600 360 370 380 390 400 410 pF1KB7 GLQVYDETEVSL-GKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRV :.. . : .: ::::.: . :::::.: :.. :...::.:::::..::.:: XP_011 GFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRF 610 620 630 640 650 660 420 430 pF1KB7 RAHGVRTSEGAEGSAQGPH :.:: XP_011 RVHGEPAH 670 >>XP_011528407 (OMIM: 613569) PREDICTED: SUN domain-cont (706 aa) initn: 520 init1: 319 opt: 543 Z-score: 483.5 bits: 99.3 E(85289): 3.4e-20 Smith-Waterman score: 543; 39.7% identity (68.2% similar) in 214 aa overlap (212-422:489-702) 190 200 210 220 230 pF1KB7 WLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELD-KLHKE-VSTVRAANSE ::.. .. : :. :.:: : : . . XP_011 GGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVH 460 470 480 490 500 510 240 250 260 270 280 290 pF1KB7 RVAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPT ...: ..:: .:: . :::: : :::. . :. : ... . .: ... : XP_011 HIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPR 520 530 540 550 560 570 300 310 320 330 340 350 pF1KB7 VILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVF :::.: : :::::::.: :: .:..: .:.. . .::.: : .. .. .:::.:::.: XP_011 VILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIF 580 590 600 610 620 630 360 370 380 390 400 410 pF1KB7 GLQVYDETEVSL-GKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRV :.. . : .: ::::.: . :::::.: :.. :...::.:::::..::.:: XP_011 GFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRF 640 650 660 670 680 690 420 430 pF1KB7 RAHGVRTSEGAEGSAQGPH :.:: XP_011 RVHGEPAH 700 437 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:41:39 2016 done: Fri Nov 4 05:41:40 2016 Total Scan time: 10.310 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]