FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7187, 539 aa 1>>>pF1KB7187 539 - 539 aa - 539 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8895+/-0.00033; mu= 4.4539+/- 0.021 mean_var=248.8759+/-50.117, 0's: 0 Z-trim(123.9): 11 B-trim: 1941 in 1/59 Lambda= 0.081299 statistics sampled from 44519 (44540) to 44519 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.522), width: 16 Scan time: 12.700 The best scores are: opt bits E(85289) NP_006565 (OMIM: 606775) chondroitin sulfate prote ( 539) 3723 449.5 1.2e-125 NP_001193872 (OMIM: 606775) chondroitin sulfate pr ( 566) 3368 407.9 4.3e-113 NP_001193873 (OMIM: 606775) chondroitin sulfate pr ( 477) 3190 386.9 7.2e-107 NP_001193871 (OMIM: 606775) chondroitin sulfate pr ( 401) 2802 341.4 3.2e-93 NP_001193874 (OMIM: 606775) chondroitin sulfate pr ( 428) 2447 299.8 1.1e-80 >>NP_006565 (OMIM: 606775) chondroitin sulfate proteogly (539 aa) initn: 3723 init1: 3723 opt: 3723 Z-score: 2376.7 bits: 449.5 E(85289): 1.2e-125 Smith-Waterman score: 3723; 100.0% identity (100.0% similar) in 539 aa overlap (1-539:1-539) 10 20 30 40 50 60 pF1KB7 MGRAGGGGPGRGPPPLLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPAWEPPANDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MGRAGGGGPGRGPPPLLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPAWEPPANDTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EEAGPPAAGEDEASWTAPGGELAGPEEVLQESAAVTGTAWLEADSPGLGGVTAEAGSGDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EEAGPPAAGEDEASWTAPGGELAGPEEVLQESAAVTGTAWLEADSPGLGGVTAEAGSGDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 QALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSFPGSPGTSENHPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSFPGSPGTSENHPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDAVGGGDLEDENEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDAVGGGDLEDENEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSENGTECR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSENGTECR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 VMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIA 430 440 450 460 470 480 490 500 510 520 530 pF1KB7 EGSHPNDDPSAPHKIQEVLKSCLKEEESFNIQNSMSPKLEGGKGDQADLDVNCLQNNLT ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EGSHPNDDPSAPHKIQEVLKSCLKEEESFNIQNSMSPKLEGGKGDQADLDVNCLQNNLT 490 500 510 520 530 >>NP_001193872 (OMIM: 606775) chondroitin sulfate proteo (566 aa) initn: 3709 init1: 3365 opt: 3368 Z-score: 2151.4 bits: 407.9 E(85289): 4.3e-113 Smith-Waterman score: 3659; 95.2% identity (95.2% similar) in 566 aa overlap (1-539:1-566) 10 20 30 40 50 60 pF1KB7 MGRAGGGGPGRGPPPLLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPAWEPPANDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRAGGGGPGRGPPPLLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPAWEPPANDTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EEAGPPAAGEDEASWTAPGGELAGPEEVLQESAAVTGTAWLEADSPGLGGVTAEAGSGDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEAGPPAAGEDEASWTAPGGELAGPEEVLQESAAVTGTAWLEADSPGLGGVTAEAGSGDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 QALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSFPGSPGTSENHPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSFPGSPGTSENHPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDAVGGGDLEDENEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDAVGGGDLEDENEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSENGTECR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSENGTECR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 VMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIA 430 440 450 460 470 480 490 500 510 pF1KB7 EGSHPN---------------------------DDPSAPHKIQEVLKSCLKEEESFNIQN :::::: ::::::::::::::::::::::::::: NP_001 EGSHPNVRKLCNTPRTSSPHARALAHYDNVICQDDPSAPHKIQEVLKSCLKEEESFNIQN 490 500 510 520 530 540 520 530 pF1KB7 SMSPKLEGGKGDQADLDVNCLQNNLT :::::::::::::::::::::::::: NP_001 SMSPKLEGGKGDQADLDVNCLQNNLT 550 560 >>NP_001193873 (OMIM: 606775) chondroitin sulfate proteo (477 aa) initn: 3190 init1: 3190 opt: 3190 Z-score: 2039.6 bits: 386.9 E(85289): 7.2e-107 Smith-Waterman score: 3190; 100.0% identity (100.0% similar) in 460 aa overlap (1-460:1-460) 10 20 30 40 50 60 pF1KB7 MGRAGGGGPGRGPPPLLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPAWEPPANDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGRAGGGGPGRGPPPLLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPAWEPPANDTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 EEAGPPAAGEDEASWTAPGGELAGPEEVLQESAAVTGTAWLEADSPGLGGVTAEAGSGDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEAGPPAAGEDEASWTAPGGELAGPEEVLQESAAVTGTAWLEADSPGLGGVTAEAGSGDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 QALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELPKESPLEVWLNLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSFPGSPGTSENHPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSFPGSPGTSENHPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 TEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDAVGGGDLEDENEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDAVGGGDLEDENEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSENGTECR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGRDLASSENGTECR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 VMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIA :::::::::::::::::::::::::::::::::::::::: NP_001 VMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTKMILVLPTKSRRFSSPA 430 440 450 460 470 490 500 510 520 530 pF1KB7 EGSHPNDDPSAPHKIQEVLKSCLKEEESFNIQNSMSPKLEGGKGDQADLDVNCLQNNLT >>NP_001193871 (OMIM: 606775) chondroitin sulfate proteo (401 aa) initn: 2802 init1: 2802 opt: 2802 Z-score: 1794.6 bits: 341.4 E(85289): 3.2e-93 Smith-Waterman score: 2802; 100.0% identity (100.0% similar) in 401 aa overlap (139-539:1-401) 110 120 130 140 150 160 pF1KB7 GGVTAEAGSGDAQALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELP :::::::::::::::::::::::::::::: NP_001 MPPAIPEATEASGPPSPTPGDKLSPASELP 10 20 30 170 180 190 200 210 220 pF1KB7 KESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSF 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB7 PGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDA 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB7 VGGGDLEDENELLVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGGGDLEDENELLVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGR 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB7 DLASSENGTECRSGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLASSENGTECRSGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHK 220 230 240 250 260 270 410 420 430 440 450 460 pF1KB7 GMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSE 280 290 300 310 320 330 470 480 490 500 510 520 pF1KB7 LHNDNFSLSTIAEGSHPNDDPSAPHKIQEVLKSCLKEEESFNIQNSMSPKLEGGKGDQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHNDNFSLSTIAEGSHPNDDPSAPHKIQEVLKSCLKEEESFNIQNSMSPKLEGGKGDQAD 340 350 360 370 380 390 530 pF1KB7 LDVNCLQNNLT ::::::::::: NP_001 LDVNCLQNNLT 400 >>NP_001193874 (OMIM: 606775) chondroitin sulfate proteo (428 aa) initn: 2788 init1: 2444 opt: 2447 Z-score: 1569.2 bits: 299.8 E(85289): 1.1e-80 Smith-Waterman score: 2738; 93.7% identity (93.7% similar) in 428 aa overlap (139-539:1-428) 110 120 130 140 150 160 pF1KB7 GGVTAEAGSGDAQALPATLQAPHEVLGQSIMPPAIPEATEASGPPSPTPGDKLSPASELP :::::::::::::::::::::::::::::: NP_001 MPPAIPEATEASGPPSPTPGDKLSPASELP 10 20 30 170 180 190 200 210 220 pF1KB7 KESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KESPLEVWLNLGGSTPDPQGPELTYPFQGTLEPQPASDIIDIDYFEGLDGEGRGADLGSF 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB7 PGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLDEEEEEEEDDKDA 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB7 VGGGDLEDENELLVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGGGDLEDENELLVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSIALRPRPGEPGR 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB7 DLASSENGTECRSGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLASSENGTECRSGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHK 220 230 240 250 260 270 410 420 430 440 450 460 pF1KB7 GMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSE 280 290 300 310 320 330 470 480 490 500 pF1KB7 LHNDNFSLSTIAEGSHPN---------------------------DDPSAPHKIQEVLKS :::::::::::::::::: ::::::::::::::: NP_001 LHNDNFSLSTIAEGSHPNVRKLCNTPRTSSPHARALAHYDNVICQDDPSAPHKIQEVLKS 340 350 360 370 380 390 510 520 530 pF1KB7 CLKEEESFNIQNSMSPKLEGGKGDQADLDVNCLQNNLT :::::::::::::::::::::::::::::::::::::: NP_001 CLKEEESFNIQNSMSPKLEGGKGDQADLDVNCLQNNLT 400 410 420 539 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:43:02 2016 done: Fri Nov 4 05:43:04 2016 Total Scan time: 12.700 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]