FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7192, 317 aa 1>>>pF1KB7192 317 - 317 aa - 317 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0824+/-0.000386; mu= -0.5472+/- 0.024 mean_var=239.7299+/-49.451, 0's: 0 Z-trim(121.0): 8 B-trim: 1815 in 2/56 Lambda= 0.082835 statistics sampled from 36919 (36931) to 36919 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.433), width: 16 Scan time: 8.530 The best scores are: opt bits E(85289) NP_004958 (OMIM: 147563) bone sialoprotein 2 precu ( 317) 2090 262.2 9.8e-70 NP_001030025 (OMIM: 300029,300455,300834,304020,31 (1152) 251 42.9 0.0037 >>NP_004958 (OMIM: 147563) bone sialoprotein 2 precursor (317 aa) initn: 2090 init1: 2090 opt: 2090 Z-score: 1372.9 bits: 262.2 E(85289): 9.8e-70 Smith-Waterman score: 2090; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317) 10 20 30 40 50 60 pF1KB7 MKTALILLSILGMACAFSMKNLHRRVKIEDSEENGVFKYRPRYYLYKHAYFYPHLKRFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MKTALILLSILGMACAFSMKNLHRRVKIEDSEENGVFKYRPRYYLYKHAYFYPHLKRFPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 QGSSDSSEENGDDSSEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QGSSDSSEENGDDSSEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDATP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GTGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGINGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GTGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGINGTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TNSTEAENGNGSSGGDNGEEGEEESVTGANAEDTTETGRQGKGTSKTTTSPNGGFEPTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TNSTEAENGNGSSGGDNGEEGEEESVTGANAEDTTETGRQGKGTSKTTTSPNGGFEPTTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 PQVYRTTSPPFGKTTTVEYEGEYEYTGANEYDNGYEIYESENGEPRGDNYRAYEDEYSYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PQVYRTTSPPFGKTTTVEYEGEYEYTGANEYDNGYEIYESENGEPRGDNYRAYEDEYSYF 250 260 270 280 290 300 310 pF1KB7 KGQGYDGYDGQNYYHHQ ::::::::::::::::: NP_004 KGQGYDGYDGQNYYHHQ 310 >>NP_001030025 (OMIM: 300029,300455,300834,304020,312610 (1152 aa) initn: 358 init1: 143 opt: 251 Z-score: 177.6 bits: 42.9 E(85289): 0.0037 Smith-Waterman score: 260; 30.7% identity (55.8% similar) in 251 aa overlap (65-307:737-986) 40 50 60 70 80 90 pF1KB7 GVFKYRPRYYLYKHAYFYPHLKRFPVQGSSDSSEENGDDSSEEEEEEEETSNEGENNEES .. ::.:: ::::.: : ..:::..: NP_001 GEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD-REEEEEKEGEGKEEGEGEEVE 710 720 730 740 750 760 100 110 120 130 140 150 pF1KB7 NEDEDSEAE-NTTLSATTLGYGED-ATPGTGYTGLAAIQLPKK--AGDITNKATKEKESD .: : :.: . : ::. . : : . . .: .:.. . ..: ... NP_001 GEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE 770 780 790 800 810 820 160 170 180 190 200 pF1KB7 EEEEEEEEGNENEESEAEVDENE-QGINGTSTNSTEAENGNGSSGGDNGE-EGEEESVTG .:::::: .:.::.:.: .:.: . .: . . :.:.:.: :..:: ::::: : NP_001 REEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG 830 840 850 860 870 880 210 220 230 240 250 260 pF1KB7 ANAEDTTETGRQGKGTSKTTTSPNG-GFEPTTPPQVYRTTSPPFGKTTTVEYEGEYEY-T . :. :.. .: .. .: : : . . :. : ::: : NP_001 EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGE 890 900 910 920 930 940 270 280 290 300 310 pF1KB7 GANEYDNGYEIYESENGEPRGDNYRAYEDEYSYFKGQGYDGYDGQNYYHHQ : .: ..: : :.:: .:.. : : . .:. .: NP_001 GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEG 950 960 970 980 990 1000 NP_001 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE 1010 1020 1030 1040 1050 1060 317 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:46:57 2016 done: Fri Nov 4 05:46:59 2016 Total Scan time: 8.530 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]