Result of FASTA (omim) for
pF1KB7195
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7195, 129 aa
1>>>pF1KB7195 129 - 129 aa - 129 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2619+/-0.000311; mu= 11.0049+/- 0.019
mean_var=68.7094+/-13.586, 0's: 0 Z-trim(117.4): 28 B-trim: 59 in 1/50
Lambda= 0.154727
statistics sampled from 29322 (29350) to 29322 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.344), width: 16
Scan time: 4.570
The best scores are: opt bits E(85289)
NP_000501 (OMIM: 136530,229070) follitropin subuni ( 129) 954 221.2 3.7e-58
NP_001018090 (OMIM: 136530,229070) follitropin sub ( 129) 954 221.2 3.7e-58
NP_000540 (OMIM: 188540,275100) thyrotropin subuni ( 138) 378 92.6 2e-19
XP_011540367 (OMIM: 188540,275100) PREDICTED: thyr ( 138) 378 92.6 2e-19
NP_000885 (OMIM: 152780,228300) lutropin subunit b ( 141) 310 77.5 7.5e-15
XP_011525277 (OMIM: 152780,228300) PREDICTED: lutr ( 157) 310 77.5 8.2e-15
NP_001305994 (OMIM: 608824) choriogonadotropin sub ( 151) 294 73.9 9.4e-14
NP_203695 (OMIM: 608823) choriogonadotropin subuni ( 155) 294 73.9 9.6e-14
NP_203696 (OMIM: 608824) choriogonadotropin subuni ( 163) 294 73.9 1e-13
NP_149439 (OMIM: 608827) chorionic gonadotropin, b ( 165) 294 73.9 1e-13
NP_149133 (OMIM: 608826) choriogonadotropin subuni ( 165) 294 73.9 1e-13
XP_016882991 (OMIM: 608826) PREDICTED: choriogonad ( 165) 294 73.9 1e-13
NP_000728 (OMIM: 118860) choriogonadotropin subuni ( 165) 294 73.9 1e-13
NP_149032 (OMIM: 608825) chorionic gonadotropin, b ( 165) 294 73.9 1e-13
XP_016881722 (OMIM: 608823) PREDICTED: choriogonad ( 173) 294 73.9 1.1e-13
XP_005258536 (OMIM: 608824) PREDICTED: choriogonad ( 181) 294 73.9 1.1e-13
NP_001264920 (OMIM: 188540,275100) thyrotropin sub ( 93) 231 59.7 1.1e-09
NP_660154 (OMIM: 609652) glycoprotein hormone beta ( 130) 225 58.5 3.6e-09
>>NP_000501 (OMIM: 136530,229070) follitropin subunit be (129 aa)
initn: 954 init1: 954 opt: 954 Z-score: 1165.1 bits: 221.2 E(85289): 3.7e-58
Smith-Waterman score: 954; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:1-129)
10 20 30 40 50 60
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPS
70 80 90 100 110 120
pF1KB7 YCSFGEMKE
:::::::::
NP_000 YCSFGEMKE
>>NP_001018090 (OMIM: 136530,229070) follitropin subunit (129 aa)
initn: 954 init1: 954 opt: 954 Z-score: 1165.1 bits: 221.2 E(85289): 3.7e-58
Smith-Waterman score: 954; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:1-129)
10 20 30 40 50 60
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 ARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPS
70 80 90 100 110 120
pF1KB7 YCSFGEMKE
:::::::::
NP_001 YCSFGEMKE
>>NP_000540 (OMIM: 188540,275100) thyrotropin subunit be (138 aa)
initn: 402 init1: 224 opt: 378 Z-score: 469.8 bits: 92.6 E(85289): 2e-19
Smith-Waterman score: 378; 40.2% identity (72.1% similar) in 122 aa overlap (4-123:7-126)
10 20 30 40 50
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVY
....: . : .:. . : :. :. ::..:: .:..:::: :::::.:::.
NP_000 MTALFLMSMLFGLTCGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDING
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 KD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVR
: : : .::.....:.::..::: :. ..:::: .:.::::..: .:: .
NP_000 KLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHE
60 70 80 90 100 110
120
pF1KB7 GLGPSYCSFGEMKE
.. .::.
NP_000 AIKTNYCTKPQKSYLVGFSV
120 130
>>XP_011540367 (OMIM: 188540,275100) PREDICTED: thyrotro (138 aa)
initn: 402 init1: 224 opt: 378 Z-score: 469.8 bits: 92.6 E(85289): 2e-19
Smith-Waterman score: 378; 40.2% identity (72.1% similar) in 122 aa overlap (4-123:7-126)
10 20 30 40 50
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVY
....: . : .:. . : :. :. ::..:: .:..:::: :::::.:::.
XP_011 MTALFLMSMLFGLTCGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDING
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 KD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVR
: : : .::.....:.::..::: :. ..:::: .:.::::..: .:: .
XP_011 KLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHE
60 70 80 90 100 110
120
pF1KB7 GLGPSYCSFGEMKE
.. .::.
XP_011 AIKTNYCTKPQKSYLVGFSV
120 130
>>NP_000885 (OMIM: 152780,228300) lutropin subunit beta (141 aa)
initn: 299 init1: 299 opt: 310 Z-score: 387.6 bits: 77.5 E(85289): 7.5e-15
Smith-Waterman score: 310; 37.4% identity (63.6% similar) in 107 aa overlap (21-127:29-135)
10 20 30 40 50
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYT
:. : .:.::: : ::..::: ::::: :
NP_000 MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 RDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDC
: . : : .::.... .:..:.::: . .: . ..::: .:.:: : ...::
NP_000 MMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDC
70 80 90 100 110 120
120
pF1KB7 TVRGLGPSYCSFGEMKE
: :. ..
NP_000 GGPKDHPLTCDHPQLSGLLFL
130 140
>>XP_011525277 (OMIM: 152780,228300) PREDICTED: lutropin (157 aa)
initn: 299 init1: 299 opt: 310 Z-score: 386.9 bits: 77.5 E(85289): 8.2e-15
Smith-Waterman score: 310; 37.4% identity (63.6% similar) in 107 aa overlap (21-127:45-151)
10 20 30 40 50
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYC
:. : .:.::: : ::..::: :::::
XP_011 EAVSLSQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYC
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB7 YTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDST
: : . : : .::.... .:..:.::: . .: . ..::: .:.:: : ...
XP_011 PTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTS
80 90 100 110 120 130
120
pF1KB7 DCTVRGLGPSYCSFGEMKE
:: : :. ..
XP_011 DCGGPKDHPLTCDHPQLSGLLFL
140 150
>>NP_001305994 (OMIM: 608824) choriogonadotropin subunit (151 aa)
initn: 274 init1: 274 opt: 294 Z-score: 367.9 bits: 73.9 E(85289): 9.4e-14
Smith-Waterman score: 294; 38.5% identity (65.4% similar) in 104 aa overlap (21-122:15-116)
10 20 30 40 50
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKD-
:. : :.:.::: : ::..::: ::::: : : .
NP_001 MGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGV
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 -PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLG
:: :.. .:..... .:..:.::: . .. . .: :: .:.:. : ..:::
NP_001 LPALPQV--VCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDCGGPKDH
60 70 80 90 100 110
120
pF1KB7 PSYCSFGEMKE
: :
NP_001 PLTCDDPRFQASSSSKAPPPSLPSPSRLPGPSDTPILPQ
120 130 140 150
>>NP_203695 (OMIM: 608823) choriogonadotropin subunit be (155 aa)
initn: 274 init1: 274 opt: 294 Z-score: 367.7 bits: 73.9 E(85289): 9.6e-14
Smith-Waterman score: 294; 38.5% identity (65.4% similar) in 104 aa overlap (21-122:27-128)
10 20 30 40 50
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRD
:. : :.:.::: : ::..::: ::::: :
NP_203 MSKRLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 LVYKD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDC
: . :: :.. .:..... .:..:.::: . .. . .: :: .:.:. : ..:::
NP_203 RVLQGVLPALPQV--VCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC
70 80 90 100 110
120
pF1KB7 TVRGLGPSYCSFGEMKE
: :
NP_203 GGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGP
120 130 140 150
>>NP_203696 (OMIM: 608824) choriogonadotropin subunit be (163 aa)
initn: 274 init1: 274 opt: 294 Z-score: 367.4 bits: 73.9 E(85289): 1e-13
Smith-Waterman score: 294; 38.5% identity (65.4% similar) in 104 aa overlap (21-122:27-128)
10 20 30 40 50
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRD
:. : :.:.::: : ::..::: ::::: :
NP_203 MSKGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 LVYKD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDC
: . :: :.. .:..... .:..:.::: . .. . .: :: .:.:. : ..:::
NP_203 RVLQGVLPALPQV--VCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC
70 80 90 100 110
120
pF1KB7 TVRGLGPSYCSFGEMKE
: :
NP_203 GGPKDHPLTCDDPRFQASSSSKAPPPSLPSPSRLPGPSDTPILPQ
120 130 140 150 160
>>NP_149439 (OMIM: 608827) chorionic gonadotropin, beta (165 aa)
initn: 274 init1: 274 opt: 294 Z-score: 367.3 bits: 73.9 E(85289): 1e-13
Smith-Waterman score: 294; 38.5% identity (65.4% similar) in 104 aa overlap (21-122:29-130)
10 20 30 40 50
pF1KB7 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYT
:. : :.:.::: : ::..::: ::::: :
NP_149 MEMFQGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 RDLVYKD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDST
: . :: :.. .:..... .:..:.::: . .. . .: :: .:.:. : ..:
NP_149 MTRVLQGVLPALPQV--VCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTT
70 80 90 100 110
120
pF1KB7 DCTVRGLGPSYCSFGEMKE
:: : :
NP_149 DCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ
120 130 140 150 160
129 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:49:56 2016 done: Fri Nov 4 05:49:57 2016
Total Scan time: 4.570 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]