FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7197, 372 aa 1>>>pF1KB7197 372 - 372 aa - 372 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3697+/-0.000345; mu= 17.7399+/- 0.022 mean_var=110.7753+/-24.939, 0's: 0 Z-trim(116.7): 749 B-trim: 1468 in 1/53 Lambda= 0.121858 statistics sampled from 27262 (28125) to 27262 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.33), width: 16 Scan time: 8.540 The best scores are: opt bits E(85289) NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 2482 447.1 2.9e-125 NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 1499 274.4 3.2e-73 NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 1499 274.4 3.2e-73 NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 1499 274.4 3.2e-73 NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 1499 274.4 3.2e-73 NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 1499 274.4 3.2e-73 NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 1499 274.4 3.3e-73 NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 1499 274.4 3.3e-73 NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 1499 274.4 3.3e-73 NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 1499 274.4 3.3e-73 NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 1499 274.4 3.5e-73 NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 1499 274.5 3.7e-73 NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 1499 274.5 3.7e-73 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 1395 256.1 1e-67 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 1395 256.1 1e-67 NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 1344 247.0 4.4e-65 NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 1318 242.4 1e-63 XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 1318 242.4 1e-63 NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 1318 242.4 1e-63 NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 1318 242.4 1e-63 NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 1318 242.4 1e-63 NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 1318 242.4 1e-63 XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1318 242.5 1.1e-63 XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1318 242.5 1.1e-63 XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1318 242.5 1.1e-63 XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1318 242.5 1.1e-63 XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1318 242.5 1.1e-63 XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1318 242.5 1.1e-63 XP_016866392 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 1318 242.5 1.1e-63 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 1250 230.6 4.6e-60 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 1250 230.6 4.6e-60 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 1250 230.6 4.6e-60 XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 1250 230.6 4.6e-60 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 1250 230.6 4.8e-60 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 1250 230.6 4.8e-60 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 1250 230.6 4.8e-60 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 1250 230.6 4.9e-60 NP_001269833 (OMIM: 165196) kappa-type opioid rece ( 291) 1237 228.2 1.9e-59 XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 1217 224.7 2.6e-58 NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 1217 224.7 2.6e-58 NP_001305784 (OMIM: 602548) nociceptin receptor is ( 341) 1155 213.8 4.7e-55 XP_011527132 (OMIM: 602548) PREDICTED: nociceptin ( 289) 1128 209.0 1.1e-53 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 930 174.3 4.1e-43 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 890 167.3 5.4e-41 NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 827 156.1 1e-37 NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 806 152.4 1.3e-36 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 806 152.5 1.5e-36 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 800 151.5 3.3e-36 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 800 151.5 3.3e-36 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 800 151.5 3.3e-36 >>NP_000902 (OMIM: 165195) delta-type opioid receptor [H (372 aa) initn: 2482 init1: 2482 opt: 2482 Z-score: 2369.8 bits: 447.1 E(85289): 2.9e-125 Smith-Waterman score: 2482; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372) 10 20 30 40 50 60 pF1KB7 MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC 310 320 330 340 350 360 370 pF1KB7 TPSDGPGGGAAA :::::::::::: NP_000 TPSDGPGGGAAA 370 >>NP_001138757 (OMIM: 600018) mu-type opioid receptor is (389 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.6 bits: 274.4 E(85289): 3.2e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_001 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_001 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_001 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_001 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQS 360 370 380 >>NP_001008504 (OMIM: 600018) mu-type opioid receptor is (392 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.6 bits: 274.4 E(85289): 3.2e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_001 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_001 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_001 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_001 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQVRSL 360 370 380 390 >>NP_001138755 (OMIM: 600018) mu-type opioid receptor is (397 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.5 bits: 274.4 E(85289): 3.2e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_001 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_001 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_001 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_001 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQRERRQKSDW 360 370 380 390 >>NP_000905 (OMIM: 600018) mu-type opioid receptor isofo (400 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.5 bits: 274.4 E(85289): 3.2e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_000 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_000 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_000 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_000 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_000 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_000 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_000 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP 360 370 380 390 400 >>NP_001138756 (OMIM: 600018) mu-type opioid receptor is (403 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.4 bits: 274.4 E(85289): 3.2e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_001 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_001 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_001 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_001 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQGPPAKFVADQLAGSS 360 370 380 390 400 >>NP_001138754 (OMIM: 600018) mu-type opioid receptor is (406 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.4 bits: 274.4 E(85289): 3.3e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_001 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_001 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_001 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_001 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQKIDLFQKSSLLNCEHTKG 360 370 380 390 400 >>NP_001272452 (OMIM: 600018) mu-type opioid receptor is (414 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.3 bits: 274.4 E(85289): 3.3e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_001 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_001 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_001 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_001 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQNYYIIHRCCCNTPLISQKPVLLWFCD 360 370 380 390 400 410 >>NP_001008503 (OMIM: 600018) mu-type opioid receptor is (418 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.2 bits: 274.4 E(85289): 3.3e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_001 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_001 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_001 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_001 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQPPLAVSMAQIFTRYPPPTHREKTCNDYMK 360 370 380 390 400 410 >>NP_001138758 (OMIM: 600018) mu-type opioid receptor is (420 aa) initn: 1479 init1: 1258 opt: 1499 Z-score: 1435.2 bits: 274.4 E(85289): 3.3e-73 Smith-Waterman score: 1499; 63.2% identity (81.4% similar) in 361 aa overlap (3-361:24-381) 10 20 30 pF1KB7 MEPAPSAGAELQ-PPLFANASDAY-PSACPSAGANASGP :::: :. .. : .: :: :. .: .. : NP_001 MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 PGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADAL : .. :. ::.: :::: ::.:::.:: :::. :::::::::::::::::::::::: NP_001 P--TGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL 70 80 90 100 110 100 110 120 130 140 150 pF1KB7 ATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL :::::::::..::: ::::: .::: :.:::::::::::::: :::::::::::::::: NP_001 ATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKAL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB7 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV ::::: .::.::.: :.:.:..:.:.: ::.:. :.:.. : : : :.:::... :::: NP_001 DFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI :.:::..:.::::::::::.:::.:::.:::::::::.::::::::::::..:.:::.:: NP_001 FIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPI 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPC ::.::. .:: : . .:. :.::::::.:: ::::::::::::::::::..: NP_001 HIYVIIKALVTIPETTFQTVS-WHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTS 300 310 320 330 340 350 340 350 360 370 pF1KB7 GRPDPSSFSRAREATARERVTACTPSDGPGGGAAA . . .. .: :. : . :: : NP_001 SNIEQQNSTRIRQNTRDHPSTANTVDRTNHQVELNLDCHCENAKPWPLSYNAGQSPFPFP 360 370 380 390 400 410 372 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:52:07 2016 done: Fri Nov 4 05:52:08 2016 Total Scan time: 8.540 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]