FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7202, 241 aa 1>>>pF1KB7202 241 - 241 aa - 241 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8569+/-0.000264; mu= 13.8230+/- 0.017 mean_var=105.8079+/-21.428, 0's: 0 Z-trim(122.6): 17 B-trim: 2155 in 1/53 Lambda= 0.124685 statistics sampled from 41016 (41035) to 41016 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.481), width: 16 Scan time: 8.010 The best scores are: opt bits E(85289) NP_612116 (OMIM: 606520) protein G6b isoform G6b-B ( 241) 1669 309.7 3e-84 XP_011513222 (OMIM: 606520) PREDICTED: protein G6b ( 257) 1540 286.5 3e-77 NP_612121 (OMIM: 606520) protein G6b isoform G6b-G ( 222) 1277 239.1 4.7e-63 NP_079536 (OMIM: 606520) protein G6b isoform G6b-A ( 237) 1277 239.2 5e-63 XP_011513223 (OMIM: 606520) PREDICTED: protein G6b ( 253) 1148 216.0 5e-56 NP_612117 (OMIM: 606520) protein G6b isoform G6b-C ( 217) 965 183.0 3.7e-46 XP_016866820 (OMIM: 606520) PREDICTED: protein G6b ( 246) 965 183.0 4e-46 NP_612118 (OMIM: 606520) protein G6b isoform G6b-D ( 193) 959 181.9 7.1e-46 NP_612119 (OMIM: 606520) protein G6b isoform G6b-E ( 197) 956 181.3 1e-45 XP_016866822 (OMIM: 606520) PREDICTED: protein G6b ( 169) 836 159.7 2.9e-39 XP_016866821 (OMIM: 606520) PREDICTED: protein G6b ( 233) 836 159.8 3.7e-39 XP_016866819 (OMIM: 606520) PREDICTED: protein G6b ( 262) 836 159.9 4.1e-39 >>NP_612116 (OMIM: 606520) protein G6b isoform G6b-B pre (241 aa) initn: 1669 init1: 1669 opt: 1669 Z-score: 1633.6 bits: 309.7 E(85289): 3e-84 Smith-Waterman score: 1669; 100.0% identity (100.0% similar) in 241 aa overlap (1-241:1-241) 10 20 30 40 50 60 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 APLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADPADASTIYAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 APLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADPADASTIYAVV 190 200 210 220 230 240 pF1KB7 V : NP_612 V >>XP_011513222 (OMIM: 606520) PREDICTED: protein G6b iso (257 aa) initn: 1540 init1: 1540 opt: 1540 Z-score: 1507.8 bits: 286.5 E(85289): 3e-77 Smith-Waterman score: 1540; 100.0% identity (100.0% similar) in 221 aa overlap (21-241:37-257) 10 20 30 40 50 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSF :::::::::::::::::::::::::::::: XP_011 EGGTPSFLLQLIQGLGRQDLVTQGPRVEEPASLDGRPGDRVNLSCGGVSHPIRWVWAPSF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 PACKGLSKGRRPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PACKGLSKGRRPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 RHEDESRTVLHVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHEDESRTVLHVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 PQPIRPLPRFAPLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPIRPLPRFAPLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADP 190 200 210 220 230 240 240 pF1KB7 ADASTIYAVVV ::::::::::: XP_011 ADASTIYAVVV 250 >>NP_612121 (OMIM: 606520) protein G6b isoform G6b-G pre (222 aa) initn: 1277 init1: 1277 opt: 1277 Z-score: 1253.0 bits: 239.1 E(85289): 4.7e-63 Smith-Waterman score: 1277; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 APLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADPADASTIYAVV : NP_612 ALSPPHSSTCENRAPEASKGGRAQDSRGPGPGTGKGMGMGRG 190 200 210 220 >>NP_079536 (OMIM: 606520) protein G6b isoform G6b-A pre (237 aa) initn: 1277 init1: 1277 opt: 1277 Z-score: 1252.6 bits: 239.2 E(85289): 5e-63 Smith-Waterman score: 1280; 86.7% identity (90.4% similar) in 218 aa overlap (1-209:1-217) 10 20 30 40 50 60 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 A---PLVKT------EPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADPA : : .: : .. . .. . :: ::.: NP_079 ALSPPHSSTCENRAPEASKGGRAQDSRGPGP-GTEPALCGSGPSSPQQAPPAVHSGPC 190 200 210 220 230 240 pF1KB7 DASTIYAVVV >>XP_011513223 (OMIM: 606520) PREDICTED: protein G6b iso (253 aa) initn: 1148 init1: 1148 opt: 1148 Z-score: 1126.8 bits: 216.0 E(85289): 5e-56 Smith-Waterman score: 1151; 85.4% identity (89.4% similar) in 198 aa overlap (21-209:37-233) 10 20 30 40 50 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSF :::::::::::::::::::::::::::::: XP_011 EGGTPSFLLQLIQGLGRQDLVTQGPRVEEPASLDGRPGDRVNLSCGGVSHPIRWVWAPSF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 PACKGLSKGRRPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PACKGLSKGRRPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 RHEDESRTVLHVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHEDESRTVLHVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLP 130 140 150 160 170 180 180 190 200 210 220 pF1KB7 PQPIRPLPRFA---PLVKT------EPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSR ::::::::::: : .: : .. . .. . :: ::.: XP_011 PQPIRPLPRFALSPPHSSTCENRAPEASKGGRAQDSRGPGP-GTEPALCGSGPSSPQQAP 190 200 210 220 230 240 230 240 pF1KB7 PRRLSTADPADASTIYAVVV XP_011 PAVHSGPC 250 >>NP_612117 (OMIM: 606520) protein G6b isoform G6b-C pre (217 aa) initn: 1377 init1: 965 opt: 965 Z-score: 949.8 bits: 183.0 E(85289): 3.7e-46 Smith-Waterman score: 1305; 84.6% identity (87.1% similar) in 241 aa overlap (1-241:1-217) 10 20 30 40 50 60 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF :::::::::::::::::. :. . .: : : : :.. NP_612 HVLGDRTYCKAPGPTHGAC-PRNRFD----------HSLDL-------LCP------PHI 130 140 150 190 200 210 220 230 240 pF1KB7 APLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADPADASTIYAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 APLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADPADASTIYAVV 160 170 180 190 200 210 pF1KB7 V : NP_612 V >>XP_016866820 (OMIM: 606520) PREDICTED: protein G6b iso (246 aa) initn: 965 init1: 965 opt: 965 Z-score: 949.1 bits: 183.0 E(85289): 4e-46 Smith-Waterman score: 965; 99.3% identity (100.0% similar) in 138 aa overlap (1-138:1-138) 10 20 30 40 50 60 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF :::::::::::::::::. XP_016 HVLGDRTYCKAPGPTHGACPRNRFDHSLDLVRLIPPHFLSPTCPLPTPQFLSLSPCWEQT 130 140 150 160 170 180 >>NP_612118 (OMIM: 606520) protein G6b isoform G6b-D pre (193 aa) initn: 956 init1: 956 opt: 959 Z-score: 944.6 bits: 181.9 E(85289): 7.1e-46 Smith-Waterman score: 959; 96.5% identity (97.9% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF ::::::::::::::::. :. NP_612 HVLGDRTYCKAPGPTHALSPPHSSTCENRAPEASKGGRAQDSRGPGPGTEPALCGSGPSS 130 140 150 160 170 180 >>NP_612119 (OMIM: 606520) protein G6b isoform G6b-E pre (197 aa) initn: 956 init1: 956 opt: 956 Z-score: 941.6 bits: 181.3 E(85289): 1e-45 Smith-Waterman score: 1255; 81.7% identity (81.7% similar) in 241 aa overlap (1-241:1-197) 10 20 30 40 50 60 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 RPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 HVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLPPQPIRPLPRF :::::::::::::::: NP_612 HVLGDRTYCKAPGPTH-------------------------------------------- 130 190 200 210 220 230 240 pF1KB7 APLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADPADASTIYAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 APLVKTEPQRPVKEEEPKIPGDLDQEPSLLYADLDHLALSRPRRLSTADPADASTIYAVV 140 150 160 170 180 190 pF1KB7 V : NP_612 V >>XP_016866822 (OMIM: 606520) PREDICTED: protein G6b iso (169 aa) initn: 836 init1: 836 opt: 836 Z-score: 825.8 bits: 159.7 E(85289): 2.9e-39 Smith-Waterman score: 836; 99.2% identity (100.0% similar) in 118 aa overlap (21-138:37-154) 10 20 30 40 50 pF1KB7 MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSF :::::::::::::::::::::::::::::: XP_016 EGGTPSFLLQLIQGLGRQDLVTQGPRVEEPASLDGRPGDRVNLSCGGVSHPIRWVWAPSF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 PACKGLSKGRRPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PACKGLSKGRRPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 RHEDESRTVLHVLGDRTYCKAPGPTHGSVYPQLLIPLLGAGLVLGLGALGLVWWLHRRLP :::::::::::::::::::::::::::. XP_016 RHEDESRTVLHVLGDRTYCKAPGPTHGACPRNRFDHSLDLLHL 130 140 150 160 241 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:54:39 2016 done: Fri Nov 4 05:54:41 2016 Total Scan time: 8.010 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]