FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7204, 189 aa 1>>>pF1KB7204 189 - 189 aa - 189 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3202+/-0.000908; mu= 12.4376+/- 0.054 mean_var=58.5301+/-11.811, 0's: 0 Z-trim(104.5): 18 B-trim: 4 in 1/49 Lambda= 0.167643 statistics sampled from 7895 (7912) to 7895 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.243), width: 16 Scan time: 1.940 The best scores are: opt bits E(32554) CCDS34996.1 IFNA16 gene_id:3449|Hs108|chr9 ( 189) 1242 308.6 1.4e-84 CCDS6498.1 IFNA4 gene_id:3441|Hs108|chr9 ( 189) 1106 275.7 1.1e-74 CCDS6500.1 IFNA17 gene_id:3451|Hs108|chr9 ( 189) 1082 269.9 6.4e-73 CCDS6499.1 IFNA10 gene_id:3446|Hs108|chr9 ( 189) 1081 269.7 7.6e-73 CCDS34995.1 IFNA7 gene_id:3444|Hs108|chr9 ( 189) 1061 264.9 2.2e-71 CCDS6497.1 IFNA21 gene_id:3452|Hs108|chr9 ( 189) 1053 262.9 8.3e-71 CCDS6501.1 IFNA14 gene_id:3448|Hs108|chr9 ( 189) 1040 259.8 7.3e-70 CCDS6502.1 IFNA5 gene_id:3442|Hs108|chr9 ( 189) 1039 259.5 8.7e-70 CCDS6506.1 IFNA2 gene_id:3440|Hs108|chr9 ( 188) 991 247.9 2.7e-66 CCDS6504.1 IFNA6 gene_id:3443|Hs108|chr9 ( 189) 975 244.1 4e-65 CCDS6507.1 IFNA8 gene_id:3445|Hs108|chr9 ( 189) 973 243.6 5.5e-65 CCDS6505.2 IFNA13 gene_id:3447|Hs108|chr9 ( 190) 944 236.6 7.2e-63 CCDS6508.1 IFNA1 gene_id:3439|Hs108|chr9 ( 189) 939 235.3 1.7e-62 CCDS6496.1 IFNW1 gene_id:3467|Hs108|chr9 ( 195) 681 173.0 1e-43 CCDS6495.1 IFNB1 gene_id:3456|Hs108|chr9 ( 187) 347 92.2 2.1e-19 CCDS34997.1 IFNE gene_id:338376|Hs108|chr9 ( 208) 340 90.5 7.4e-19 >>CCDS34996.1 IFNA16 gene_id:3449|Hs108|chr9 (189 aa) initn: 1242 init1: 1242 opt: 1242 Z-score: 1631.7 bits: 308.6 E(32554): 1.4e-84 Smith-Waterman score: 1242; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN 130 140 150 160 170 180 pF1KB7 LQKGLRRKD ::::::::: CCDS34 LQKGLRRKD >>CCDS6498.1 IFNA4 gene_id:3441|Hs108|chr9 (189 aa) initn: 1106 init1: 1106 opt: 1106 Z-score: 1454.0 bits: 275.7 E(32554): 1.1e-74 Smith-Waterman score: 1106; 88.9% identity (95.2% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: CCDS64 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE ::.: :::.:::::::::..:::::::::::::.::::::...::.:: ::.::::::: CCDS64 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::: ::::::: ::::::::::::::::::::: ::::::::::::::::::.::::: CCDS64 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN 130 140 150 160 170 180 pF1KB7 LQKGLRRKD ::: ::::: CCDS64 LQKRLRRKD >>CCDS6500.1 IFNA17 gene_id:3451|Hs108|chr9 (189 aa) initn: 1082 init1: 1082 opt: 1082 Z-score: 1422.6 bits: 269.9 E(32554): 6.4e-73 Smith-Waterman score: 1082; 87.3% identity (94.7% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG :::::::::::::::::::::::::::::::::::::::::::::::: :::::::.::: CCDS65 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE .::: ::::::::.::::..:::::::::::::.::::::...::.:: ::.::::.:: CCDS65 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::: ::::.:: ::::::::::::::::::::: ::::::::::::::::::.::::: CCDS65 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN 130 140 150 160 170 180 pF1KB7 LQKGLRRKD ::: ::::: CCDS65 LQKILRRKD >>CCDS6499.1 IFNA10 gene_id:3446|Hs108|chr9 (189 aa) initn: 1081 init1: 1081 opt: 1081 Z-score: 1421.3 bits: 269.7 E(32554): 7.6e-73 Smith-Waterman score: 1081; 87.3% identity (94.7% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG :::::::::::::::::::::::::::::::::::::::::.:::::: :::::::.:: CCDS64 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE .::: :::::::::::::..:::::::::::::.::::::...::.:: ::.::::::: CCDS64 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::: ::::::: :::::::::::::::::::::. .:::::::::::::::::.::::: CCDS64 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN 130 140 150 160 170 180 pF1KB7 LQKGLRRKD ::: ::::: CCDS64 LQKRLRRKD >>CCDS34995.1 IFNA7 gene_id:3444|Hs108|chr9 (189 aa) initn: 1061 init1: 1061 opt: 1061 Z-score: 1395.2 bits: 264.9 E(32554): 2.2e-71 Smith-Waterman score: 1061; 85.7% identity (93.7% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG :: ::::::.:::::::::::::::::::::: ::::::::::::::: :::::::..: CCDS34 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE ::.: :::.::::.::::..:::::::::::::.::::::...::.:: ::.::::::: CCDS34 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::: ::::::: ::::: :::::::::::::::: :::::::::::::::::::::::: CCDS34 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN 130 140 150 160 170 180 pF1KB7 LQKGLRRKD :.::::::: CCDS34 LKKGLRRKD >>CCDS6497.1 IFNA21 gene_id:3452|Hs108|chr9 (189 aa) initn: 1074 init1: 1053 opt: 1053 Z-score: 1384.7 bits: 262.9 E(32554): 8.3e-71 Smith-Waterman score: 1053; 85.7% identity (92.6% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG :::::::::::::::::::::::::::::::::::::::::::::::: :::::::.::: CCDS64 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE :::: :::::::::::::..::::::::::::::::::.:...::.:: :: ::::::: CCDS64 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::: ::::::: ::: ::::::.:::::::::: ::::::::::::::::::::.: CCDS64 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI 130 140 150 160 170 180 pF1KB7 LQKGLRRKD .:. ::::. CCDS64 FQERLRRKE >>CCDS6501.1 IFNA14 gene_id:3448|Hs108|chr9 (189 aa) initn: 1040 init1: 1040 opt: 1040 Z-score: 1367.7 bits: 259.8 E(32554): 7.3e-70 Smith-Waterman score: 1040; 83.6% identity (93.1% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG ::: :.:.::..::: :: :::::.: :::::.:::.:.:.::: ::: :::::::.:: CCDS65 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE :::: :::::::::::::..:::.::::::::::.::::::::::.:::::::::.:::: CCDS65 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::: ::::::: ::::::::::.::::::::::: ::::::::::::::::::.::::: CCDS65 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN 130 140 150 160 170 180 pF1KB7 LQKGLRRKD ::: ::::: CCDS65 LQKRLRRKD >>CCDS6502.1 IFNA5 gene_id:3442|Hs108|chr9 (189 aa) initn: 1039 init1: 1039 opt: 1039 Z-score: 1366.4 bits: 259.5 E(32554): 8.7e-70 Smith-Waterman score: 1039; 82.5% identity (93.1% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG ::: : ::::..::. ::::::::::::::::.:::.:...::::::: :::::::.::: CCDS65 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE :::: :::::::::::::..::::::::::::::::::.:::::::::: ::.::::::: CCDS65 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::. ::::::. ::: ::::.:::::::::::: ::::::::::::::::::::.:.: CCDS65 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN 130 140 150 160 170 180 pF1KB7 LQKGLRRKD ::. ::::. CCDS65 LQERLRRKE >>CCDS6506.1 IFNA2 gene_id:3440|Hs108|chr9 (188 aa) initn: 989 init1: 654 opt: 991 Z-score: 1303.7 bits: 247.9 E(32554): 2.7e-66 Smith-Waterman score: 991; 81.0% identity (91.0% similar) in 189 aa overlap (1-189:1-188) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG :::.:.::.:.:::: :: ::.:::::::::::.::.:.::::: ::: :::::::.::: CCDS65 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE :::: : :::::::..: ..:::::: :::::::::::::::::::::: ::.::::::: CCDS65 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::: : ::: : ::.:::::::::::::::::: ::::::::::::::::::::.::: CCDS65 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN 120 130 140 150 160 170 pF1KB7 LQKGLRRKD ::..:: :. CCDS65 LQESLRSKE 180 >>CCDS6504.1 IFNA6 gene_id:3443|Hs108|chr9 (189 aa) initn: 975 init1: 975 opt: 975 Z-score: 1282.7 bits: 244.1 E(32554): 4e-65 Smith-Waterman score: 975; 79.9% identity (88.9% similar) in 189 aa overlap (1-189:1-189) 10 20 30 40 50 60 pF1KB7 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG ::: :.::::..::: :: ::: ::::::::::.::...::::: ::: :::::::.:: CCDS65 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE :::: :::::::::.:::..::.::::::::::::::.:::: ::::.: ::.::::::: CCDS65 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN ::: ::: : ::::::::::::::::::::: :::::::::::::::::::: : : CCDS65 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN 130 140 150 160 170 180 pF1KB7 LQKGLRRKD ::. ::::. CCDS65 LQERLRRKE 189 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:56:36 2016 done: Fri Nov 4 05:56:36 2016 Total Scan time: 1.940 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]