FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7205, 426 aa 1>>>pF1KB7205 426 - 426 aa - 426 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7598+/-0.000313; mu= 11.5998+/- 0.020 mean_var=116.8307+/-23.183, 0's: 0 Z-trim(119.9): 18 B-trim: 13 in 1/52 Lambda= 0.118658 statistics sampled from 34554 (34572) to 34554 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.405), width: 16 Scan time: 10.580 The best scores are: opt bits E(85289) NP_149059 (OMIM: 606362) testicular acid phosphata ( 426) 2922 510.8 2.6e-144 NP_001601 (OMIM: 171650,200950) lysosomal acid pho ( 423) 1112 201.0 4.9e-51 NP_001289418 (OMIM: 171650,200950) lysosomal acid ( 395) 1072 194.1 5.3e-49 NP_001090 (OMIM: 171790) prostatic acid phosphatas ( 386) 1034 187.6 4.7e-47 XP_011511248 (OMIM: 171790) PREDICTED: prostatic a ( 387) 1034 187.6 4.8e-47 NP_001127666 (OMIM: 171790) prostatic acid phospha ( 418) 1034 187.6 5.1e-47 NP_001289419 (OMIM: 171650,200950) lysosomal acid ( 391) 942 171.8 2.6e-42 NP_001289421 (OMIM: 171650,200950) lysosomal acid ( 236) 514 98.4 2e-20 NP_001289420 (OMIM: 171650,200950) lysosomal acid ( 360) 513 98.4 3.2e-20 NP_001278966 (OMIM: 171790) prostatic acid phospha ( 353) 479 92.6 1.8e-18 XP_011511249 (OMIM: 171790) PREDICTED: prostatic a ( 385) 479 92.6 1.9e-18 NP_057445 (OMIM: 611471) lysophosphatidic acid pho ( 428) 211 46.7 0.00013 XP_016856911 (OMIM: 611471) PREDICTED: lysophospha ( 386) 209 46.4 0.00015 XP_011507903 (OMIM: 611471) PREDICTED: lysophospha ( 401) 209 46.4 0.00016 NP_001310554 (OMIM: 611471) lysophosphatidic acid ( 403) 209 46.4 0.00016 >>NP_149059 (OMIM: 606362) testicular acid phosphatase p (426 aa) initn: 2922 init1: 2922 opt: 2922 Z-score: 2711.8 bits: 510.8 E(85289): 2.6e-144 Smith-Waterman score: 2922; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426) 10 20 30 40 50 60 pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 TLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 AGLFPEAAPGSPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 AGLFPEAAPGSPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 GWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISAL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 DIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLALQGALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 DIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLALQGALG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 LYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 RFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPGCLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 RFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPGCLR 370 380 390 400 410 420 pF1KB7 ALGGPV :::::: NP_149 ALGGPV >>NP_001601 (OMIM: 171650,200950) lysosomal acid phospha (423 aa) initn: 705 init1: 544 opt: 1112 Z-score: 1037.3 bits: 201.0 E(85289): 4.9e-51 Smith-Waterman score: 1112; 44.4% identity (68.9% similar) in 428 aa overlap (1-417:1-412) 10 20 30 40 50 pF1KB7 MAGL-GFWGHPAGPLLLLL---LLVLPP-RALPEGPLVFVALVFRHGDRAPLASYPMDPH ::: . :.. :. : ::: :.:.:: :: : ::.:..:::::.:. .:: ::. NP_001 MAGKRSGWSR-AALLQLLLGVNLVVMPPTRA---RSLRFVTLLYRHGDRSPVKTYPKDPY 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 KEVASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLES .: ::.:.:::: ::. :. :::. ::.::..::. :.:.:::.::::::::: : NP_001 QEEE---WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 AQANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAA :.:::::::: . .:. :.::::::::..::.::.::. ::::..: :. .. NP_001 AEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 EYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRT :::. . ::. . : :::. . :. .:.: :::.:.:.::: :: ::::.... NP_001 EYQNESSRNAQFLDMVANETGLTDL--TLETVWNVYDTLFCEQTHGLRLPPWASPQTMQR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 LAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLG-LPLKMVMYSAHDSTL :.... ... : . ::::.: ::.:: : :.. . . :: :...:::::.:: NP_001 LSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP-KLLVYSAHDTTL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LALQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPG .::: :: .:.:. :::.: ::. . .:.:: .: ...::.: . : :::::: NP_001 VALQMALDVYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPG 300 310 320 330 340 360 370 380 390 400 pF1KB7 CPAPCPLGRFYQLTAPARPPAHGVSCH---GPYEAAIPPAPVVPLLAGAVAVLVALSLGL :: ::: : .:: :. : :. :: .. . : .: . ... :.. . NP_001 CPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLF 350 360 370 380 390 400 410 420 pF1KB7 GLLAWRPGCLRALGGPV . : :: NP_001 RMQAQPPGYRHVADGEDHA 410 420 >>NP_001289418 (OMIM: 171650,200950) lysosomal acid phos (395 aa) initn: 787 init1: 543 opt: 1072 Z-score: 1000.7 bits: 194.1 E(85289): 5.3e-49 Smith-Waterman score: 1072; 44.4% identity (69.7% similar) in 390 aa overlap (34-417:8-384) 10 20 30 40 50 60 pF1KB7 LGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVASTLW .:.: .:::::.:. .:: ::..: : NP_001 MGVRMTEYVGL-YRHGDRSPVKTYPKDPYQE---EEW 10 20 30 70 80 90 100 110 120 pF1KB7 PRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANLAGL :.:.:::: ::. :. :::. ::.::..::. :.:.:::.::::::::: ::.:::::: NP_001 PQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 FPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALEG :: . .:. :.::::::::..::.::.::. ::::..: :. .. :::. NP_001 FPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSR 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 WTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISALD . ::. . : :::. . :. .:.: :::.:.:.::: :: ::::.... :.... .. NP_001 NAQFLDMVANETGLTDL--TLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 IGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLG-LPLKMVMYSAHDSTLLALQGALG . : . ::::.: ::.:: : :.. . . :: :...:::::.::.::: :: NP_001 FRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP-KLLVYSAHDTTLVALQMALD 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB7 LYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLG .:.:. :::.: ::. . .:.:: .: ...::.: . : :::::::: ::: NP_001 VYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQ 280 290 300 310 320 370 380 390 400 410 pF1KB7 RFYQLTAPARPPAHGVSCH---GPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPG : .:: :. : :. :: .. . : .: . ... :.. . . : :: NP_001 DFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPG 330 340 350 360 370 380 420 pF1KB7 CLRALGGPV NP_001 YRHVADGEDHA 390 >>NP_001090 (OMIM: 171790) prostatic acid phosphatase is (386 aa) initn: 972 init1: 307 opt: 1034 Z-score: 965.7 bits: 187.6 E(85289): 4.7e-47 Smith-Waterman score: 1034; 43.3% identity (70.6% similar) in 367 aa overlap (15-378:18-372) 10 20 30 40 50 pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE .:.::. :.. : ::.::::::::.:. ..: :: :: NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ . ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::. NP_001 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY .:::.::: . . .: :.::::::::..::.:: .:.:.:::..:: :. .. :. NP_001 TNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL :. :. . :.. : ...:: :. : : :: : :.:...:.. ::.::. :.. : NP_001 QKRLHPYKDFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA ..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. . NP_001 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP :: :: .:.: ::::.: :: . . :. : ..:::.. : : :: :::: NP_001 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW ::: :: .:..:. : .. : NP_001 PSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD 350 360 370 380 >>XP_011511248 (OMIM: 171790) PREDICTED: prostatic acid (387 aa) initn: 972 init1: 307 opt: 1034 Z-score: 965.7 bits: 187.6 E(85289): 4.8e-47 Smith-Waterman score: 1034; 43.3% identity (70.6% similar) in 367 aa overlap (15-378:18-372) 10 20 30 40 50 pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE .:.::. :.. : ::.::::::::.:. ..: :: :: XP_011 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ . ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::. XP_011 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY .:::.::: . . .: :.::::::::..::.:: .:.:.:::..:: :. .. :. XP_011 TNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL :. :. . :.. : ...:: :. : : :: : :.:...:.. ::.::. :.. : XP_011 QKRLHPYKDFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA ..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. . XP_011 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP :: :: .:.: ::::.: :: . . :. : ..:::.. : : :: :::: XP_011 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW ::: :: .:..:. : .. : XP_011 PSCPLERFAELVGPVIPQDWSTECMTTNSHQGSSFHIQY 350 360 370 380 >>NP_001127666 (OMIM: 171790) prostatic acid phosphatase (418 aa) initn: 950 init1: 307 opt: 1034 Z-score: 965.2 bits: 187.6 E(85289): 5.1e-47 Smith-Waterman score: 1034; 43.3% identity (70.6% similar) in 367 aa overlap (15-378:18-372) 10 20 30 40 50 pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE .:.::. :.. : ::.::::::::.:. ..: :: :: NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ . ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::. NP_001 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY .:::.::: . . .: :.::::::::..::.:: .:.:.:::..:: :. .. :. NP_001 TNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL :. :. . :.. : ...:: :. : : :: : :.:...:.. ::.::. :.. : NP_001 QKRLHPYKDFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA ..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. . NP_001 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP :: :: .:.: ::::.: :: . . :. : ..:::.. : : :: :::: NP_001 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW ::: :: .:..:. : .. : NP_001 PSCPLERFAELVGPVIPQDWSTECMTTNSHQVLKVIFAVAFCLISAVLMVLLFIHIRRGL 350 360 370 380 390 400 >>NP_001289419 (OMIM: 171650,200950) lysosomal acid phos (391 aa) initn: 650 init1: 489 opt: 942 Z-score: 880.5 bits: 171.8 E(85289): 2.6e-42 Smith-Waterman score: 942; 42.1% identity (66.8% similar) in 385 aa overlap (40-417:5-380) 10 20 30 40 50 60 pF1KB7 PAGPLLLLLLLVLPPRALPEGPLVFVALVFRHG-DRAPLASYPMDPHKEVASTLWPRGLG : : .:: : . . . : :.: NP_001 MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLR 10 20 30 70 80 90 100 110 120 pF1KB7 QLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANLAGLFPEAA .: ::. :. :::. ::.::..::. :.:.:::.::::::::: ::.:::::::: . NP_001 FVTLEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNG 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 PG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALEGWTGFL .:. :.::::::::..::.::.::. ::::..: :. .. :::. . :: NP_001 MQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 SRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISALDIGAHV . . : :::. . :. .:.: :::.:.:.::: :: ::::.... :.... ... NP_001 DMVANETGLTDL--TLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLF 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 GPPRAAEKAQLTGGILLNAILANFSRVQRLG-LPLKMVMYSAHDSTLLALQGALGLYDGH : . ::::.: ::.:: : :.. . . :: :...:::::.::.::: :: .:.:. NP_001 GIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP-KLLVYSAHDTTLVALQMALDVYNGE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB7 TPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLGRFYQL :::.: ::. . .:.:: .: ...::.: . : :::::::: ::: : .: NP_001 QAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRL 280 290 300 310 320 370 380 390 400 410 420 pF1KB7 TAPARPPAHGVSCH---GPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPGCLRAL : :. : :. :: .. . : .: . ... :.. . . : :: NP_001 TEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVA 330 340 350 360 370 380 pF1KB7 GGPV NP_001 DGEDHA 390 >>NP_001289421 (OMIM: 171650,200950) lysosomal acid phos (236 aa) initn: 493 init1: 332 opt: 514 Z-score: 487.7 bits: 98.4 E(85289): 2e-20 Smith-Waterman score: 514; 39.0% identity (64.9% similar) in 231 aa overlap (191-417:4-225) 170 180 190 200 210 220 pF1KB7 RYHELLREATEAAEYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGL : :::. . :. .:.: :::.:.:.::: NP_001 MVANETGLTDL--TLETVWNVYDTLFCEQTHGL 10 20 30 230 240 250 260 270 pF1KB7 PLPAWASPDVLRTLAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLG-LP :: ::::.... :.... ... : . ::::.: ::.:: : :.. . . :: NP_001 RLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP 40 50 60 70 80 90 280 290 300 310 320 330 pF1KB7 LKMVMYSAHDSTLLALQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRN :...:::::.::.::: :: .:.:. :::.: ::. . .:.:: .: ...:: NP_001 -KLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRN 100 110 120 130 140 340 350 360 370 380 390 pF1KB7 DSAHLPLPLSLPGCPAPCPLGRFYQLTAPARPPAHGVSCH---GPYEAAIPPAPVVPLLA .: . : :::::::: ::: : .:: :. : :. :: .. . : .: NP_001 ESDKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSI 150 160 170 180 190 200 400 410 420 pF1KB7 GAVAVLVALSLGLGLLAWRPGCLRALGGPV . ... :.. . . : :: NP_001 LFLLIVLLLTVLFRMQAQPPGYRHVADGEDHA 210 220 230 >>NP_001289420 (OMIM: 171650,200950) lysosomal acid phos (360 aa) initn: 719 init1: 295 opt: 513 Z-score: 484.1 bits: 98.4 E(85289): 3.2e-20 Smith-Waterman score: 814; 38.3% identity (58.6% similar) in 428 aa overlap (1-417:1-349) 10 20 30 40 50 pF1KB7 MAGL-GFWGHPAGPLLLLL---LLVLPP-RALPEGPLVFVALVFRHGDRAPLASYPMDPH ::: . :.. :. : ::: :.:.:: :: : ::.:..:::::.:. .:: ::. NP_001 MAGKRSGWSR-AALLQLLLGVNLVVMPPTRARS---LRFVTLLYRHGDRSPVKTYPKDPY 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 KEVASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLES .: ::.:.:::: ::. :. :::. ::.::..::. :.:.:::.::::::::: : NP_001 QE---EEWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 AQANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAA :.:::::::: . .:. :.::::::::..::. NP_001 AEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDR----------------------- 120 130 140 150 180 190 200 210 220 230 pF1KB7 EYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRT :.::: :: ::::.... NP_001 ------------------------------------------QTHGLRLPPWASPQTMQR 160 240 250 260 270 280 290 pF1KB7 LAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLG-LPLKMVMYSAHDSTL :.... ... : . ::::.: ::.:: : :.. . . :: :...:::::.:: NP_001 LSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP-KLLVYSAHDTTL 170 180 190 200 210 220 300 310 320 330 340 350 pF1KB7 LALQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPG .::: :: .:.:. :::.: ::. . .:.:: .: ...::.: . : :::::: NP_001 VALQMALDVYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPG 230 240 250 260 270 280 360 370 380 390 400 pF1KB7 CPAPCPLGRFYQLTAPARPPAHGVSCH---GPYEAAIPPAPVVPLLAGAVAVLVALSLGL :: ::: : .:: :. : :. :: .. . : .: . ... :.. . NP_001 CPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLF 290 300 310 320 330 340 410 420 pF1KB7 GLLAWRPGCLRALGGPV . : :: NP_001 RMQAQPPGYRHVADGEDHA 350 360 >>NP_001278966 (OMIM: 171790) prostatic acid phosphatase (353 aa) initn: 833 init1: 307 opt: 479 Z-score: 452.8 bits: 92.6 E(85289): 1.8e-18 Smith-Waterman score: 862; 39.8% identity (63.8% similar) in 367 aa overlap (15-378:18-339) 10 20 30 40 50 pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE .:.::. :.. : ::.::::::::.:. ..: :: :: NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ . ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::. NP_001 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY .:::.::: . . .: :.::::::::..::. NP_001 TNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQ------------------------- 120 130 140 150 180 190 200 210 220 230 pF1KB7 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL :.. : ...:: :. : : :: : :.:...:.. ::.::. :.. : NP_001 --------DFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKL 160 170 180 190 200 240 250 260 270 280 290 pF1KB7 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA ..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. . NP_001 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB7 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP :: :: .:.: ::::.: :: . . :. : ..:::.. : : :: :::: NP_001 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS 270 280 290 300 310 360 370 380 390 400 410 pF1KB7 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW ::: :: .:..:. : .. : NP_001 PSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD 320 330 340 350 426 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:57:10 2016 done: Fri Nov 4 05:57:12 2016 Total Scan time: 10.580 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]