FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7206, 575 aa 1>>>pF1KB7206 575 - 575 aa - 575 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3924+/-0.00104; mu= 9.4408+/- 0.062 mean_var=143.7980+/-30.058, 0's: 0 Z-trim(108.4): 46 B-trim: 90 in 1/49 Lambda= 0.106954 statistics sampled from 10152 (10181) to 10152 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.313), width: 16 Scan time: 3.300 The best scores are: opt bits E(32554) CCDS13213.2 BPIFB4 gene_id:149954|Hs108|chr20 ( 614) 3733 588.2 1e-167 CCDS13212.1 BPIFB3 gene_id:359710|Hs108|chr20 ( 476) 843 142.2 1.4e-33 CCDS13211.1 BPIFB6 gene_id:128859|Hs108|chr20 ( 453) 742 126.6 6.8e-29 CCDS13210.1 BPIFB2 gene_id:80341|Hs108|chr20 ( 458) 477 85.7 1.4e-16 CCDS13906.1 BPIFC gene_id:254240|Hs108|chr22 ( 507) 367 68.7 1.9e-11 >>CCDS13213.2 BPIFB4 gene_id:149954|Hs108|chr20 (614 aa) initn: 3733 init1: 3733 opt: 3733 Z-score: 3124.6 bits: 588.2 E(32554): 1e-167 Smith-Waterman score: 3733; 100.0% identity (100.0% similar) in 575 aa overlap (1-575:40-614) 10 20 30 pF1KB7 MLQQSDALHSALREVPLGVGDIPYNDFHVR :::::::::::::::::::::::::::::: CCDS13 LSVVAVCGTSHETNTVLRVTKDVLSNAISGMLQQSDALHSALREVPLGVGDIPYNDFHVR 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB7 GPPPVYTNGKKLDGIYQYGHIETNDNTAQLGGKYRYGEILESEGSIRDLRNSGYRSAENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GPPPVYTNGKKLDGIYQYGHIETNDNTAQLGGKYRYGEILESEGSIRDLRNSGYRSAENA 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB7 YGGHRGLGRYRAAPVGRLHRRELQPGEIPPGVATGAVGPGGLLGTGGMLAADGILAGQGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YGGHRGLGRYRAAPVGRLHRRELQPGEIPPGVATGAVGPGGLLGTGGMLAADGILAGQGG 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 LLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGVYL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 SLYTRVAINGKSLIGFLDIAVEVNITAKVRLTMDRTGYPRLVIERCDTLLGGIKVKLLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SLYTRVAINGKSLIGFLDIAVEVNITAKVRLTMDRTGYPRLVIERCDTLLGGIKVKLLRG 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 LLPNLVDNLVNRVLADVLPDLLCPIVDVVLGLVNDQLGLVDSLIPLGILGSVQYTFSSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LLPNLVDNLVNRVLADVLPDLLCPIVDVVLGLVNDQLGLVDSLIPLGILGSVQYTFSSLP 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB7 LVTGEFLELDLNTLVGEAGGGLIDYPLGWPAVSPKPMPELPPMGDNTKSQLAMSANFLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LVTGEFLELDLNTLVGEAGGGLIDYPLGWPAVSPKPMPELPPMGDNTKSQLAMSANFLGS 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB7 VLTLLQKQHALDLDITNGMFEELPPLTTATLGALIPKVFQQYPESCPLIIRIQVLNPPSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VLTLLQKQHALDLDITNGMFEELPPLTTATLGALIPKVFQQYPESCPLIIRIQVLNPPSV 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB7 MLQKDKALVKVLATAEVMVSQPKDLETTICLIDVDTEFLASFSTEGDKLMIDAKLEKTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MLQKDKALVKVLATAEVMVSQPKDLETTICLIDVDTEFLASFSTEGDKLMIDAKLEKTSL 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB7 NLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPKILNIDFSNADIDVLEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPKILNIDFSNADIDVLEDL 550 560 570 580 590 600 pF1KB7 LVLSA ::::: CCDS13 LVLSA 610 >>CCDS13212.1 BPIFB3 gene_id:359710|Hs108|chr20 (476 aa) initn: 937 init1: 347 opt: 843 Z-score: 716.2 bits: 142.2 E(32554): 1.4e-33 Smith-Waterman score: 988; 37.8% identity (69.4% similar) in 471 aa overlap (105-574:28-473) 80 90 100 110 120 130 pF1KB7 SIRDLRNSGYRSAENAYGGHRGLGRYRAAPVGRLHRRELQPGEIPPGVATGAVGPGGLLG :: : : .. :. .. .. :: : . CCDS13 MQPVMLALWSLLLLWGLATPCQELLETVGTLAR--IDKDELGKAIQNSLVGEPILQN 10 20 30 40 50 140 150 160 170 180 190 pF1KB7 TGGMLAADGILAGQGGLLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELT . : .. : . ::::.::::: ::::: :::.::. : ..::.: ::: CCDS13 VLG-----SVTAVNRGLLGSGGLLGGGGLLGHGGVFGVVEE---------LSGLKIEELT 60 70 80 90 100 200 210 220 230 240 250 pF1KB7 LPRVSVRLLPGVGVYLSLYTRVAINGKS-LIGFLDIAVEVNITAKVRLTMDRTGYPRLVI ::.: ..:::: :: :::.:.:... .. : :.:..:.:::.:..: :... : : :.. CCDS13 LPKVLLKLLPGFGVQLSLHTKVGMHCSGPLGGLLQLAAEVNVTSRVALAVSSRGTPILIL 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB7 ERCDTLLGGIKVKLLRGLLPNLVDNLVNRVLADVLPDLLCPIVDVVLGLVNDQLGLVDSL .::.:::: ...:. ::::. . ..:...: ::: ::::.:: :::.::. :: : .: CCDS13 KRCSTLLG--HISLFSGLLPTPLFGVVEQMLFKVLPGLLCPVVDSVLGVVNELLGAVLGL 170 180 190 200 210 320 330 340 350 360 370 pF1KB7 IPLGILGSVQYTFSSLPLVTGEFLELDLNTLVGEAGGGLIDYPLGWPAVSPKPMPELPPM . :: ::::......:::......:::.: .: ..: .::.: . .: ..:: CCDS13 VSLGALGSVEFSLATLPLISNQYIELDINPIVKSVAGDIIDFP---KSRAPA---KVPPK 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB7 GDNTKSQLAMSANFLGSVLTLLQKQHALDLDITNGMFEELPPLTTATLGALIPKVFQQYP :.: ::. . ...... ::: . :::.::: . ::::. :.::.:... . : CCDS13 KDHT-SQVMVPLYLFNTTFGLLQTNGALDMDITPELVPSDVPLTTTDLAALLPEALGKLP 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB7 ESCPLIIRIQVLNPPSVMLQKDKALVKVLATAEVMVSQPKDLETTICLIDVDTEFLASFS :.. ..: . :.: :.. ::::.. :. .:. :: .. .. :... CCDS13 LHQQLLLFLRVREAPTVTLHNKKALVSLPANIHVLFYVPKGTPESLFELNSVMTVRAQLA 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB7 TEGDKLMIDAKLEKTSLNLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPK . :: :. .::. :... .: . :: . .: . .. .. : .:..: :.:::: CCDS13 PSATKLHISLSLERLSVKVASSFTHAFDGSRLEEWLSHVVGAVYAPKLNVALDVGIPLPK 400 410 420 430 440 450 560 570 pF1KB7 ILNIDFSNADIDVLEDLLVLSA .:::.:::. ....:. .::. CCDS13 VLNINFSNSVLEIVENAVVLTVAS 460 470 >>CCDS13211.1 BPIFB6 gene_id:128859|Hs108|chr20 (453 aa) initn: 654 init1: 240 opt: 742 Z-score: 632.3 bits: 126.6 E(32554): 6.8e-29 Smith-Waterman score: 742; 31.8% identity (70.4% similar) in 399 aa overlap (179-573:58-448) 150 160 170 180 190 200 pF1KB7 GGLLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGV .. ..:::.:.. .. :: ... ..::::. CCDS13 MDIMNQVQSAMDESHILEKMAAEAGKKQPGMKPIKGITNLKVKDVQLPVITLNFVPGVGI 30 40 50 60 70 80 210 220 230 240 250 260 pF1KB7 YLSLYTRVAINGKSLIGF-LDIAVEVNITAKVRLTMDR-TGYPRLVIERCDTLLGGIKVK . . : ....:::..: ..: : .:::: :: :. :: : . : :...: ..:.. CCDS13 FQCVSTGMTVTGKSFMGGNMEIIVALNITATNRLLRDEETGLPVFKSEGCEVILVNVKTN 90 100 110 120 130 140 270 280 290 300 310 320 pF1KB7 LLRGLLPNLVDNLVNRVLADVLPDLLCPIVDVVLGLVNDQLGLVDSLIPLGILGSVQYTF : ..::..:..... .: ::: :.:: .:.:: :: . ... .:.: .:.:.:.. CCDS13 LPSNMLPKMVNKFLDSTLHKVLPGLMCPAIDAVLVYVNRKWTNLSDPMPVGQMGTVKYVL 150 160 170 180 190 200 330 340 350 360 370 380 pF1KB7 SSLPLVTGEFLELDLNTLVGEAGGGLIDYPLGWPAVSPKPMPELPPMGDNTKSQLAMSAN : : .:. ...::.. .: . : : . :.. .:: :. ::: . :. CCDS13 MSAPATTASYIQLDFSPVVQQQKGKTIKLADAGEALT---FPEGYAKGS---SQLLLPAT 210 220 230 240 250 260 390 400 410 420 430 440 pF1KB7 FLGSVLTLLQKQHALDLDITNGMFEELPPLTTATLGALIPKVFQQYPESCPLIIRIQVLN ::.. :.:::: .. ..: . :. :::: :: ::. .::.: ::.: :: .:.. . CCDS13 FLSAELALLQK--SFHVNIQDTMIGELPPQTTKTLARFIPEVAVAYPKSKPLTTQIKIKK 270 280 290 300 310 450 460 470 480 490 500 pF1KB7 PPSVMLQKDKALVKVLATAEVMVSQPKD-LETTICLIDVDTEFLASFSTEGDKLMIDAKL ::.: .. :.:... .: :..... .. .. :..: .. ...:.. ..:.. ..: CCDS13 PPKVTMKTGKSLLHLHSTLEMFAARWRSKAPMSLFLLEVHFNLKVQYSVHENQLQMATSL 320 330 340 350 360 370 510 520 530 540 550 560 pF1KB7 EKT-SLNLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPKILNIDFSNADI .. ::. ..:..:::. . .. . .. :..:..: :: :.::: .: .... :.. CCDS13 DRLLSLSRKSSSIGNFNERELTGFITSYLEEAYIPVVNDVLQVGLPLPDFLAMNYNLAEL 380 390 400 410 420 430 570 pF1KB7 DVLEDLLVLSA :..:. :.: CCDS13 DIVENALMLDLKLG 440 450 >>CCDS13210.1 BPIFB2 gene_id:80341|Hs108|chr20 (458 aa) initn: 460 init1: 204 opt: 477 Z-score: 411.2 bits: 85.7 E(32554): 1.4e-16 Smith-Waterman score: 477; 26.8% identity (61.4% similar) in 396 aa overlap (186-575:67-452) 160 170 180 190 200 210 pF1KB7 GLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGVYLSLYTR : .::... .::. .... : :: : . CCDS13 VSEIGKAPLQRALQVTVPHFLDWSGEALQPTRIRILNVHVPRLHLKFIAGFGVRLLAAAN 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB7 VAINGKSLIGFLDIAVEVNITAKVRLTMDRTGYPRLVIERCDTLLGGIKVKLLRGLLPNL ... :.... :.. : .:.:.. : . : :. . : . . . CCDS13 FTFKVFRAPEPLELTLPVELLADTRVTQSSIRTPVVSISACSLFSGHANEFDGSNSTSHA 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB7 VDNLVNRVLADVLPDLLC-PIVDVVLGLVNDQLGLVDSLIPLGILGSVQYTFSSLPLVTG . ::.. . :: . :: : ..: : :: .:: . .: :.: ....:.. :.: ::. CCDS13 LLVLVQKHIKAVLSNKLCLSISNLVQG-VNVHLGTLIGLNPVGPESQIRYSMVSVPTVTS 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB7 EFLELDLNTLVGEAGGGLIDYPLGWPAVSPKPM-PELPPMGDNTKSQLA---MSANFLGS ... :..:... . :: : . : : . : .:....: .: ... : CCDS13 DYISLEVNAVL---------FLLGKPIILPTDATPFVLPRHVGTEGSMATVGLSQQLFDS 220 230 240 250 260 400 410 420 430 440 450 pF1KB7 VLTLLQKQHALDLDITNGMFEELPPLTTATLGALIPKVFQQYPESCPLIIRIQVLNPPSV .: :::: ::.::::. . . :.:..:: :::.: .:.:: :....... : . CCDS13 ALLLLQKAGALNLDITGQLRSDDNLLNTSALGRLIPEVARQFPEPMPVVLKVRLGATPVA 270 280 290 300 310 320 460 470 480 490 500 pF1KB7 MLQKDKALVKVLATAEVMVSQPKDLETTICLIDVDTEFLASFSTEGDKLM-IDAKLEKTS ::. ..: ... .::... .. .. .:: ... ..:. ::. . : .. CCDS13 MLHTNNATLRLQPFVEVLATASNSAFQSLFSLDVVVNLRLQLSVSKVKLQGTTSVLGDVQ 330 340 350 360 370 380 510 520 530 540 550 560 pF1KB7 LNLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPKILNIDFSNADIDVLED :.. .:::: .: ...:. .:. .. .::.:. :. :: ..:. . .: : : CCDS13 LTVASSNVGFIDTDQVRTLMGTVFEKPLLDHLNALLAMGIALPGVVNLHYVAPEIFVYEG 390 400 410 420 430 440 570 pF1KB7 LLVLSA .:.:. CCDS13 YVVISSGLFYQS 450 >>CCDS13906.1 BPIFC gene_id:254240|Hs108|chr22 (507 aa) initn: 263 init1: 214 opt: 367 Z-score: 318.8 bits: 68.7 E(32554): 1.9e-11 Smith-Waterman score: 367; 24.8% identity (58.3% similar) in 408 aa overlap (186-574:81-473) 160 170 180 190 200 210 pF1KB7 GLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGVYLSLYTR ....: ...: .:. ..::::. .: .. CCDS13 EQMLKEKKLPDLSGSESLEFLKVDYVNYNFSNIKISAFSFPNTSLAFVPGVGIK-ALTNH 60 70 80 90 100 220 230 240 250 260 pF1KB7 VAINGKSLIGF----------LDIAVE-VNITAKVRLTMDRTGYPRLVIERCDTLLGGIK . : .. :: :. . : .:. . :: . :.: : .. : . :. . CCDS13 GTANISTDWGFESPLFQDTGGADLFLSGVYFTGIIILTRNDFGHPTLKLQDCYAQLSHAH 110 120 130 140 150 160 270 280 290 300 310 320 pF1KB7 VKLLRGLLPNLVDNLVNRVLADVLPDL---LCPIVDVVLGLVNDQLGLVDSLIPLGILGS :.. : : : ..... . .: .: ::::. . .: .:. .. : . CCDS13 VSF-SGELSVLYNSFAEPMEKPILKNLNEMLCPIIASEVKALNANLSTLEVLTKIDNYTL 170 180 190 200 210 220 330 340 350 360 370 380 pF1KB7 VQYTFSSLPLVTGEFLELDLNTLVGEAGGGLIDYPLGWPAVSP-KPMPELPPMGDNTKSQ ..:.. : : .: ..:.:.:. :.. ::: . : .:.: . : .:. CCDS13 LDYSLISSPEITENYLDLNLK--------GVF-YPLENLTDPPFSPVPFVLPERSNSMLY 230 240 250 260 270 390 400 410 420 430 440 pF1KB7 LAMSANFLGSVLTLLQKQHALDLDITNGMFEELPPLTTATLGALIPKVFQQYPESCPLII .... :. :. .... ... . . .. :: .. .. . : : :... CCDS13 IGIAEYFFKSASFAHFTAGVFNVTLSTEEISNHFVQNSQGLGNVLSRIAEIYILSQPFMV 280 290 300 310 320 330 450 460 470 480 490 pF1KB7 RIQVLNPPSVMLQKDKALVKVLATAEVMVSQPKDLETTICLIDVDTEFLASFSTE----G ::.. .:: . :: . . . :. .:..:::. .:. : :. .:.:: :. : CCDS13 RIMATEPPIINLQPGNFTLDIPASI-MMLTQPKN--STVETI-VSMDFVASTSVGLVILG 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB7 DKLMIDAKLEKTSLNLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPKILN ..:. . .:.. : : :: .:... .: .. .:. .. .: :: : .: :: . . CCDS13 QRLVCSLSLNRFRLALPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLSNPHK 400 410 420 430 440 450 560 570 pF1KB7 IDFSNADIDVLEDLLVLSA . : :.::.::: .:..: CCDS13 FLFVNSDIEVLEGFLLISTDLKYETSSKQQPSFHVWEGLNLISRQWRGKSAP 460 470 480 490 500 575 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 05:57:46 2016 done: Fri Nov 4 05:57:46 2016 Total Scan time: 3.300 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]