FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7213, 142 aa 1>>>pF1KB7213 142 - 142 aa - 142 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7140+/-0.000691; mu= 15.0543+/- 0.041 mean_var=74.1098+/-14.378, 0's: 0 Z-trim(111.0): 20 B-trim: 43 in 1/50 Lambda= 0.148983 statistics sampled from 12030 (12040) to 12030 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.37), width: 16 Scan time: 1.520 The best scores are: opt bits E(32554) CCDS200.1 PLA2G2E gene_id:30814|Hs108|chr1 ( 142) 1058 235.7 7.3e-63 CCDS201.1 PLA2G2A gene_id:5320|Hs108|chr1 ( 144) 487 113.0 6.5e-26 CCDS202.1 PLA2G5 gene_id:5322|Hs108|chr1 ( 138) 428 100.3 4.1e-22 CCDS203.1 PLA2G2D gene_id:26279|Hs108|chr1 ( 145) 427 100.1 4.9e-22 CCDS204.2 PLA2G2F gene_id:64600|Hs108|chr1 ( 211) 422 99.2 1.4e-21 CCDS10555.1 PLA2G10 gene_id:8399|Hs108|chr16 ( 165) 397 93.7 4.7e-20 CCDS9195.1 PLA2G1B gene_id:5319|Hs108|chr12 ( 148) 308 74.5 2.5e-14 CCDS47919.1 OC90 gene_id:729330|Hs108|chr8 ( 477) 277 68.4 5.8e-12 >>CCDS200.1 PLA2G2E gene_id:30814|Hs108|chr1 (142 aa) initn: 1058 init1: 1058 opt: 1058 Z-score: 1242.1 bits: 235.7 E(32554): 7.3e-63 Smith-Waterman score: 1058; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 CCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNL 70 80 90 100 110 120 130 140 pF1KB7 GTYNRKYAHYPNKLCTGPTPPC :::::::::::::::::::::: CCDS20 GTYNRKYAHYPNKLCTGPTPPC 130 140 >>CCDS201.1 PLA2G2A gene_id:5320|Hs108|chr1 (144 aa) initn: 500 init1: 440 opt: 487 Z-score: 578.8 bits: 113.0 E(32554): 6.5e-26 Smith-Waterman score: 487; 53.6% identity (67.4% similar) in 138 aa overlap (6-142:9-144) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGK-SALQYNDYGCYCGIGGSHWPVD :.... :: : ::::.: ::. ::: .::.:. :::.::.:: : : CCDS20 MKTLLLLAVIMIFGLLQA--HGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 QTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCF :: :: .::::: :::: :: :. .: :: : : :: . .:. ::::: :: :: CCDS20 ATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCF 60 70 80 90 100 110 120 130 140 pF1KB7 RRNLGTYNRKYAHYPNKLCTGPTPPC :: :::.:: .: :: : : :: : CCDS20 ARNKTTYNKKYQYYSNKHCRGSTPRC 120 130 140 >>CCDS202.1 PLA2G5 gene_id:5322|Hs108|chr1 (138 aa) initn: 445 init1: 358 opt: 428 Z-score: 510.5 bits: 100.3 E(32554): 4.1e-22 Smith-Waterman score: 428; 45.7% identity (66.7% similar) in 129 aa overlap (9-136:10-138) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSAL-QYNDYGCYCGIGGSHWPVDQT :: : : :.:... ::::.:::.:: .:. :::::: :: : : : CCDS20 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRR :::: ::: ::::::. ::. . ..: . . . : :. : ::.. . :..: CCDS20 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 120 130 140 pF1KB7 NLGTYNRKYAHYPNKLCTGPTPPC :: .:: .: ..:: ::. CCDS20 NLRSYNPQYQYFPNILCS 130 >>CCDS203.1 PLA2G2D gene_id:26279|Hs108|chr1 (145 aa) initn: 351 init1: 210 opt: 427 Z-score: 509.0 bits: 100.1 E(32554): 4.9e-22 Smith-Waterman score: 427; 39.2% identity (67.1% similar) in 143 aa overlap (7-142:3-145) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVAL-----VTGNLVQFGVMIEKMTGK-SALQYNDYGCYCGIGGSHWP :..:: ::.. . :...... :....::: :.: :::.::.:: : CCDS20 MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQP 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 VDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTT-CQRLTCECDKRAA : :::::..::::: .:. :: . : .. :. .: :. . . :.. : :::..: CCDS20 KDATDWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVA 60 70 80 90 100 110 120 130 140 pF1KB7 LCFRRNLGTYNRKYAHYPNKLCTGPTPPC .:..::: ::... : : : :: : CCDS20 FCLKRNLDTYQKRLRFYWRPHCRGQTPGC 120 130 140 >>CCDS204.2 PLA2G2F gene_id:64600|Hs108|chr1 (211 aa) initn: 413 init1: 242 opt: 422 Z-score: 501.2 bits: 99.2 E(32554): 1.4e-21 Smith-Waterman score: 422; 43.8% identity (69.5% similar) in 128 aa overlap (19-142:63-188) 10 20 30 40 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSA-LQYNDYGCYCG :.:... .:.: .::.:: :.. :::::: CCDS20 CPSRTSRSSLGMKKFFTVAILAGSVLSTAHGSLLNLKAMVEAVTGRSAILSFVGYGCYCG 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB7 IGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSV-SERGIFCA--GRTTCQRL .:: : :..::::::::::: .: ::.: ...: .. .. : :. ..: :.. CCDS20 LGGRGQPKDEVDWCCHAHDCCYQELFDQGCHPYVDHYDHTIENNTEIVCSDLNKTECDKQ 100 110 120 130 140 150 110 120 130 140 pF1KB7 TCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC :: ::: .::. . :: ..: . : : :::: : CCDS20 TCMCDKNMVLCLMNQ--TYREEYRGFLNVYCQGPTPNCSIYEPPPEEVTCSHQSPAPPAP 160 170 180 190 200 210 CCDS20 P >>CCDS10555.1 PLA2G10 gene_id:8399|Hs108|chr16 (165 aa) initn: 396 init1: 252 opt: 397 Z-score: 473.5 bits: 93.7 E(32554): 4.7e-20 Smith-Waterman score: 397; 42.7% identity (68.2% similar) in 110 aa overlap (34-142:57-164) 10 20 30 40 50 60 pF1KB7 PHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCH .. . : :::.::.:: : : ::::: CCDS10 GPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCH 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB7 AHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCA-GRTTCQRLTCECDKRAALCFRRNLGT .::::: : :. :: :: :.: .. .....:. ... ::.: :.::.. : :. .. CCDS10 GHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQT--E 90 100 110 120 130 140 130 140 pF1KB7 YNRKYAHYPNKLCTGPTPPC :: :: ::. :: .: : CCDS10 YNLKYLFYPQFLCEPDSPKCD 150 160 >>CCDS9195.1 PLA2G1B gene_id:5319|Hs108|chr12 (148 aa) initn: 258 init1: 202 opt: 308 Z-score: 370.7 bits: 74.5 E(32554): 2.5e-14 Smith-Waterman score: 308; 39.2% identity (64.2% similar) in 120 aa overlap (23-133:26-143) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSA--LQYNDYGCYCGIGGSHWPV :: ::. . : :.::.::::::.::: :: CCDS91 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV 10 20 30 40 50 60 60 70 80 90 100 pF1KB7 DQTDWCCHAHDCCYGRLEKL-GCE-----PKLEKYLFSVSERGIFCAGRTT-CQRLTCEC :. : ::..:: :: . .:: .:. : . : .: : .: :.... :. . :.: CCDS91 DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC 70 80 90 100 110 120 110 120 130 140 pF1KB7 DKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC :. ::.:: . . ::. . . .: CCDS91 DRNAAICFSK--APYNKAHKNLDTKKYCQS 130 140 >>CCDS47919.1 OC90 gene_id:729330|Hs108|chr8 (477 aa) initn: 203 init1: 165 opt: 277 Z-score: 328.3 bits: 68.4 E(32554): 5.8e-12 Smith-Waterman score: 277; 33.1% identity (60.5% similar) in 124 aa overlap (23-142:307-425) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSH :.: :. .:.. ....:::::: : CCDS47 ENDPEETTEKACDRFTFLHLGSGDNMQVMPQLGEMLFCLTSRCPEEFESYGCYCGQEGRG 280 290 300 310 320 330 60 70 80 90 100 pF1KB7 WPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFS---VSERGIFCAGRTTCQRLTCECD : :. : :: .: :: ....::: ::. .: .. :.:.. :..: : :: CCDS47 EPRDDLDRCCLSHHCCLEQVRRLGCL--LERLPWSPVVCVDHTPKCGGQSLCEKLLCACD 340 350 360 370 380 390 110 120 130 140 pF1KB7 KRAALCFRRNLGTYNRKYAHYPNKL-CTGPTPPC . :: :. ...:.. . :..: : : : CCDS47 QTAAECMTS--ASFNQSL-KSPSRLGCPGQPAACEDSLHPVPAAPTLGSSSEEDSEEDPP 400 410 420 430 440 450 CCDS47 QEDLGRAKRFLRKSLGPLGIGPLHGR 460 470 142 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:01:15 2016 done: Fri Nov 4 06:01:16 2016 Total Scan time: 1.520 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]