FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7213, 142 aa 1>>>pF1KB7213 142 - 142 aa - 142 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6947+/-0.000322; mu= 14.8591+/- 0.020 mean_var=70.6638+/-13.913, 0's: 0 Z-trim(117.1): 37 B-trim: 114 in 1/51 Lambda= 0.152572 statistics sampled from 28728 (28767) to 28728 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.337), width: 16 Scan time: 4.160 The best scores are: opt bits E(85289) NP_001155201 (OMIM: 172411) phospholipase A2, memb ( 144) 487 115.5 2.9e-26 NP_001155199 (OMIM: 172411) phospholipase A2, memb ( 144) 487 115.5 2.9e-26 NP_001155200 (OMIM: 172411) phospholipase A2, memb ( 144) 487 115.5 2.9e-26 NP_000291 (OMIM: 172411) phospholipase A2, membran ( 144) 487 115.5 2.9e-26 XP_011539893 (OMIM: 228980,601192) PREDICTED: calc ( 138) 428 102.5 2.3e-22 XP_011539894 (OMIM: 228980,601192) PREDICTED: calc ( 138) 428 102.5 2.3e-22 XP_011539891 (OMIM: 228980,601192) PREDICTED: calc ( 138) 428 102.5 2.3e-22 NP_000920 (OMIM: 228980,601192) calcium-dependent ( 138) 428 102.5 2.3e-22 XP_011539889 (OMIM: 228980,601192) PREDICTED: calc ( 138) 428 102.5 2.3e-22 XP_011539892 (OMIM: 228980,601192) PREDICTED: calc ( 138) 428 102.5 2.3e-22 XP_011539890 (OMIM: 228980,601192) PREDICTED: calc ( 138) 428 102.5 2.3e-22 XP_005245950 (OMIM: 228980,601192) PREDICTED: calc ( 138) 428 102.5 2.3e-22 XP_005245949 (OMIM: 228980,601192) PREDICTED: calc ( 169) 428 102.6 2.7e-22 XP_005245948 (OMIM: 228980,601192) PREDICTED: calc ( 169) 428 102.6 2.7e-22 XP_011539888 (OMIM: 228980,601192) PREDICTED: calc ( 169) 428 102.6 2.7e-22 NP_036532 (OMIM: 605630) group IID secretory phosp ( 145) 427 102.3 2.8e-22 NP_073730 (OMIM: 616793) group IIF secretory phosp ( 211) 422 101.4 7.9e-22 XP_011540258 (OMIM: 616793) PREDICTED: group IIF s ( 211) 422 101.4 7.9e-22 NP_003552 (OMIM: 603603) group 10 secretory phosph ( 165) 397 95.8 3e-20 NP_000919 (OMIM: 172410) phospholipase A2 precurso ( 148) 308 76.1 2.2e-14 XP_011540257 (OMIM: 616793) PREDICTED: group IIF s ( 219) 296 73.6 1.8e-13 XP_011521000 (OMIM: 603603) PREDICTED: group 10 se ( 120) 276 69.0 2.5e-12 XP_011520999 (OMIM: 603603) PREDICTED: group 10 se ( 124) 276 69.0 2.5e-12 XP_011520998 (OMIM: 603603) PREDICTED: group 10 se ( 131) 276 69.0 2.6e-12 XP_011520997 (OMIM: 603603) PREDICTED: group 10 se ( 133) 276 69.0 2.7e-12 NP_001073868 (OMIM: 601658) otoconin-90 precursor ( 477) 277 69.8 5.7e-12 NP_001258743 (OMIM: 605630) group IID secretory ph ( 62) 147 40.3 0.00054 >>NP_001155201 (OMIM: 172411) phospholipase A2, membrane (144 aa) initn: 500 init1: 440 opt: 487 Z-score: 592.4 bits: 115.5 E(85289): 2.9e-26 Smith-Waterman score: 487; 53.6% identity (67.4% similar) in 138 aa overlap (6-142:9-144) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGK-SALQYNDYGCYCGIGGSHWPVD :.... :: : ::::.: ::. ::: .::.:. :::.::.:: : : NP_001 MKTLLLLAVIMIFGLLQA--HGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 QTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCF :: :: .::::: :::: :: :. .: :: : : :: . .:. ::::: :: :: NP_001 ATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCF 60 70 80 90 100 110 120 130 140 pF1KB7 RRNLGTYNRKYAHYPNKLCTGPTPPC :: :::.:: .: :: : : :: : NP_001 ARNKTTYNKKYQYYSNKHCRGSTPRC 120 130 140 >>NP_001155199 (OMIM: 172411) phospholipase A2, membrane (144 aa) initn: 500 init1: 440 opt: 487 Z-score: 592.4 bits: 115.5 E(85289): 2.9e-26 Smith-Waterman score: 487; 53.6% identity (67.4% similar) in 138 aa overlap (6-142:9-144) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGK-SALQYNDYGCYCGIGGSHWPVD :.... :: : ::::.: ::. ::: .::.:. :::.::.:: : : NP_001 MKTLLLLAVIMIFGLLQA--HGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 QTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCF :: :: .::::: :::: :: :. .: :: : : :: . .:. ::::: :: :: NP_001 ATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCF 60 70 80 90 100 110 120 130 140 pF1KB7 RRNLGTYNRKYAHYPNKLCTGPTPPC :: :::.:: .: :: : : :: : NP_001 ARNKTTYNKKYQYYSNKHCRGSTPRC 120 130 140 >>NP_001155200 (OMIM: 172411) phospholipase A2, membrane (144 aa) initn: 500 init1: 440 opt: 487 Z-score: 592.4 bits: 115.5 E(85289): 2.9e-26 Smith-Waterman score: 487; 53.6% identity (67.4% similar) in 138 aa overlap (6-142:9-144) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGK-SALQYNDYGCYCGIGGSHWPVD :.... :: : ::::.: ::. ::: .::.:. :::.::.:: : : NP_001 MKTLLLLAVIMIFGLLQA--HGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 QTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCF :: :: .::::: :::: :: :. .: :: : : :: . .:. ::::: :: :: NP_001 ATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCF 60 70 80 90 100 110 120 130 140 pF1KB7 RRNLGTYNRKYAHYPNKLCTGPTPPC :: :::.:: .: :: : : :: : NP_001 ARNKTTYNKKYQYYSNKHCRGSTPRC 120 130 140 >>NP_000291 (OMIM: 172411) phospholipase A2, membrane as (144 aa) initn: 500 init1: 440 opt: 487 Z-score: 592.4 bits: 115.5 E(85289): 2.9e-26 Smith-Waterman score: 487; 53.6% identity (67.4% similar) in 138 aa overlap (6-142:9-144) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGK-SALQYNDYGCYCGIGGSHWPVD :.... :: : ::::.: ::. ::: .::.:. :::.::.:: : : NP_000 MKTLLLLAVIMIFGLLQA--HGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKD 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 QTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCF :: :: .::::: :::: :: :. .: :: : : :: . .:. ::::: :: :: NP_000 ATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCF 60 70 80 90 100 110 120 130 140 pF1KB7 RRNLGTYNRKYAHYPNKLCTGPTPPC :: :::.:: .: :: : : :: : NP_000 ARNKTTYNKKYQYYSNKHCRGSTPRC 120 130 140 >>XP_011539893 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 445 init1: 358 opt: 428 Z-score: 522.4 bits: 102.5 E(85289): 2.3e-22 Smith-Waterman score: 428; 45.7% identity (66.7% similar) in 129 aa overlap (9-136:10-138) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSAL-QYNDYGCYCGIGGSHWPVDQT :: : : :.:... ::::.:::.:: .:. :::::: :: : : : XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRR :::: ::: ::::::. ::. . ..: . . . : :. : ::.. . :..: XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 120 130 140 pF1KB7 NLGTYNRKYAHYPNKLCTGPTPPC :: .:: .: ..:: ::. XP_011 NLRSYNPQYQYFPNILCS 130 >>XP_011539894 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 445 init1: 358 opt: 428 Z-score: 522.4 bits: 102.5 E(85289): 2.3e-22 Smith-Waterman score: 428; 45.7% identity (66.7% similar) in 129 aa overlap (9-136:10-138) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSAL-QYNDYGCYCGIGGSHWPVDQT :: : : :.:... ::::.:::.:: .:. :::::: :: : : : XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRR :::: ::: ::::::. ::. . ..: . . . : :. : ::.. . :..: XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 120 130 140 pF1KB7 NLGTYNRKYAHYPNKLCTGPTPPC :: .:: .: ..:: ::. XP_011 NLRSYNPQYQYFPNILCS 130 >>XP_011539891 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 445 init1: 358 opt: 428 Z-score: 522.4 bits: 102.5 E(85289): 2.3e-22 Smith-Waterman score: 428; 45.7% identity (66.7% similar) in 129 aa overlap (9-136:10-138) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSAL-QYNDYGCYCGIGGSHWPVDQT :: : : :.:... ::::.:::.:: .:. :::::: :: : : : XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRR :::: ::: ::::::. ::. . ..: . . . : :. : ::.. . :..: XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 120 130 140 pF1KB7 NLGTYNRKYAHYPNKLCTGPTPPC :: .:: .: ..:: ::. XP_011 NLRSYNPQYQYFPNILCS 130 >>NP_000920 (OMIM: 228980,601192) calcium-dependent phos (138 aa) initn: 445 init1: 358 opt: 428 Z-score: 522.4 bits: 102.5 E(85289): 2.3e-22 Smith-Waterman score: 428; 45.7% identity (66.7% similar) in 129 aa overlap (9-136:10-138) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSAL-QYNDYGCYCGIGGSHWPVDQT :: : : :.:... ::::.:::.:: .:. :::::: :: : : : NP_000 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRR :::: ::: ::::::. ::. . ..: . . . : :. : ::.. . :..: NP_000 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 120 130 140 pF1KB7 NLGTYNRKYAHYPNKLCTGPTPPC :: .:: .: ..:: ::. NP_000 NLRSYNPQYQYFPNILCS 130 >>XP_011539889 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 445 init1: 358 opt: 428 Z-score: 522.4 bits: 102.5 E(85289): 2.3e-22 Smith-Waterman score: 428; 45.7% identity (66.7% similar) in 129 aa overlap (9-136:10-138) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSAL-QYNDYGCYCGIGGSHWPVDQT :: : : :.:... ::::.:::.:: .:. :::::: :: : : : XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRR :::: ::: ::::::. ::. . ..: . . . : :. : ::.. . :..: XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 120 130 140 pF1KB7 NLGTYNRKYAHYPNKLCTGPTPPC :: .:: .: ..:: ::. XP_011 NLRSYNPQYQYFPNILCS 130 >>XP_011539892 (OMIM: 228980,601192) PREDICTED: calcium- (138 aa) initn: 445 init1: 358 opt: 428 Z-score: 522.4 bits: 102.5 E(85289): 2.3e-22 Smith-Waterman score: 428; 45.7% identity (66.7% similar) in 129 aa overlap (9-136:10-138) 10 20 30 40 50 pF1KB7 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSAL-QYNDYGCYCGIGGSHWPVDQT :: : : :.:... ::::.:::.:: .:. :::::: :: : : : XP_011 MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 DWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRR :::: ::: ::::::. ::. . ..: . . . : :. : ::.. . :..: XP_011 DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR 70 80 90 100 110 120 120 130 140 pF1KB7 NLGTYNRKYAHYPNKLCTGPTPPC :: .:: .: ..:: ::. XP_011 NLRSYNPQYQYFPNILCS 130 142 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:01:16 2016 done: Fri Nov 4 06:01:17 2016 Total Scan time: 4.160 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]