FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7228, 595 aa 1>>>pF1KB7228 595 - 595 aa - 595 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7453+/-0.000525; mu= 16.1585+/- 0.032 mean_var=71.0114+/-14.047, 0's: 0 Z-trim(108.1): 51 B-trim: 0 in 0/51 Lambda= 0.152198 statistics sampled from 16117 (16168) to 16117 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.536), E-opt: 0.2 (0.19), width: 16 Scan time: 9.700 The best scores are: opt bits E(85289) NP_071889 (OMIM: 606193) solute carrier family 13 ( 595) 3932 873.4 0 NP_001311329 (OMIM: 606193) solute carrier family ( 471) 2549 569.7 7.5e-162 XP_011514819 (OMIM: 606193) PREDICTED: solute carr ( 587) 2543 568.4 2.3e-161 XP_016868043 (OMIM: 606193) PREDICTED: solute carr ( 608) 2543 568.4 2.3e-161 XP_011514817 (OMIM: 606193) PREDICTED: solute carr ( 651) 2543 568.5 2.5e-161 XP_011514821 (OMIM: 606193) PREDICTED: solute carr ( 340) 1437 325.5 1.8e-88 XP_011514820 (OMIM: 606193) PREDICTED: solute carr ( 346) 1437 325.5 1.8e-88 XP_016868044 (OMIM: 606193) PREDICTED: solute carr ( 352) 1437 325.5 1.9e-88 XP_011514818 (OMIM: 606193) PREDICTED: solute carr ( 617) 1437 325.6 3e-88 NP_036582 (OMIM: 604309) solute carrier family 13 ( 626) 1404 318.4 4.7e-86 NP_001305121 (OMIM: 604309) solute carrier family ( 627) 1395 316.4 1.8e-85 XP_016867451 (OMIM: 604309) PREDICTED: solute carr ( 575) 1394 316.1 2e-85 XP_006722228 (OMIM: 604148) PREDICTED: solute carr ( 549) 1214 276.6 1.5e-73 XP_011523754 (OMIM: 604148) PREDICTED: solute carr ( 593) 1214 276.6 1.6e-73 XP_011523753 (OMIM: 604148) PREDICTED: solute carr ( 598) 1214 276.6 1.6e-73 XP_011523752 (OMIM: 604148) PREDICTED: solute carr ( 642) 1214 276.6 1.7e-73 NP_003975 (OMIM: 604148) solute carrier family 13 ( 592) 1213 276.4 1.9e-73 NP_001139447 (OMIM: 604148) solute carrier family ( 641) 1213 276.4 2e-73 NP_001271438 (OMIM: 608305,615905) solute carrier ( 551) 1166 266.1 2.2e-70 NP_001271439 (OMIM: 608305,615905) solute carrier ( 525) 1162 265.2 4e-70 NP_808218 (OMIM: 608305,615905) solute carrier fam ( 568) 1162 265.2 4.2e-70 NP_001180271 (OMIM: 606411) solute carrier family ( 504) 1076 246.3 1.8e-64 NP_001011554 (OMIM: 606411) solute carrier family ( 555) 1076 246.3 2e-64 NP_073740 (OMIM: 606411) solute carrier family 13 ( 602) 1076 246.3 2.2e-64 NP_001180268 (OMIM: 606411) solute carrier family ( 552) 880 203.3 1.8e-51 XP_011523755 (OMIM: 604148) PREDICTED: solute carr ( 569) 738 172.1 4.5e-42 NP_001180269 (OMIM: 606411) solute carrier family ( 520) 636 149.7 2.3e-35 XP_016867452 (OMIM: 604309) PREDICTED: solute carr ( 374) 622 146.6 1.5e-34 XP_011514326 (OMIM: 604309) PREDICTED: solute carr ( 581) 622 146.6 2.1e-34 XP_011523756 (OMIM: 604148) PREDICTED: solute carr ( 471) 560 133.0 2.2e-30 XP_011522097 (OMIM: 608305,615905) PREDICTED: solu ( 498) 538 128.2 6.7e-29 NP_001137310 (OMIM: 608305,615905) solute carrier ( 522) 538 128.2 6.9e-29 XP_016877754 (OMIM: 203200,227220,611409) PREDICTE ( 676) 176 48.7 7.4e-05 XP_016877753 (OMIM: 203200,227220,611409) PREDICTE ( 780) 176 48.8 8.3e-05 XP_016877752 (OMIM: 203200,227220,611409) PREDICTE ( 791) 176 48.8 8.5e-05 XP_016877751 (OMIM: 203200,227220,611409) PREDICTE ( 793) 176 48.8 8.5e-05 XP_016877750 (OMIM: 203200,227220,611409) PREDICTE ( 795) 176 48.8 8.5e-05 NP_001287913 (OMIM: 203200,227220,611409) P protei ( 814) 176 48.8 8.7e-05 XP_016877748 (OMIM: 203200,227220,611409) PREDICTE ( 822) 176 48.8 8.7e-05 XP_016877747 (OMIM: 203200,227220,611409) PREDICTE ( 835) 176 48.8 8.9e-05 XP_016877746 (OMIM: 203200,227220,611409) PREDICTE ( 836) 176 48.8 8.9e-05 NP_000266 (OMIM: 203200,227220,611409) P protein i ( 838) 176 48.8 8.9e-05 XP_016877745 (OMIM: 203200,227220,611409) PREDICTE ( 846) 176 48.8 9e-05 XP_011519942 (OMIM: 203200,227220,611409) PREDICTE ( 852) 176 48.8 9e-05 XP_016877744 (OMIM: 203200,227220,611409) PREDICTE ( 860) 176 48.8 9.1e-05 XP_016877749 (OMIM: 203200,227220,611409) PREDICTE ( 814) 165 46.3 0.00046 >>NP_071889 (OMIM: 606193) solute carrier family 13 memb (595 aa) initn: 3932 init1: 3932 opt: 3932 Z-score: 4666.3 bits: 873.4 E(85289): 0 Smith-Waterman score: 3932; 100.0% identity (100.0% similar) in 595 aa overlap (1-595:1-595) 10 20 30 40 50 60 pF1KB7 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 CLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 IWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 IWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 WFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 WFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 LITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 VTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVF 490 500 510 520 530 540 550 560 570 580 590 pF1KB7 SYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP 550 560 570 580 590 >>NP_001311329 (OMIM: 606193) solute carrier family 13 m (471 aa) initn: 2535 init1: 2535 opt: 2549 Z-score: 3026.7 bits: 569.7 E(85289): 7.5e-162 Smith-Waterman score: 2549; 88.7% identity (92.1% similar) in 441 aa overlap (158-595:37-471) 130 140 150 160 170 180 pF1KB7 MSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGS---TNHGLEID ..: : : :..:. :.:: : . NP_001 SLLMEKVGVFPQCPNPLPLVPSQSKEGKSLLLNKEEE-ESNQQRVFTGSWVRKRMKLLLA 10 20 30 40 50 60 190 200 210 220 230 240 pF1KB7 ESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLTCLCI ....: .:. .: : . : : ::::::::::::::::::::::::: NP_001 YTLESHLLNKTLTFGLVIPQV-----KPFQDVPLSKNSGMRTKYRTKKGHVTRKLTCLCI 70 80 90 100 110 120 250 260 270 280 290 300 pF1KB7 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ 130 140 150 160 170 180 310 320 330 340 350 360 pF1KB7 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR 190 200 210 220 230 240 370 380 390 400 410 420 pF1KB7 DPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITW 250 260 270 280 290 300 430 440 450 460 470 480 pF1KB7 KEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSL 310 320 330 340 350 360 490 500 510 520 530 540 pF1KB7 TEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGH 370 380 390 400 410 420 550 560 570 580 590 pF1KB7 LKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP 430 440 450 460 470 >>XP_011514819 (OMIM: 606193) PREDICTED: solute carrier (587 aa) initn: 2535 init1: 2535 opt: 2543 Z-score: 3018.1 bits: 568.4 E(85289): 2.3e-161 Smith-Waterman score: 3406; 90.5% identity (90.5% similar) in 587 aa overlap (65-595:1-587) 40 50 60 70 80 90 pF1KB7 AECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVIC :::::::::::::::::::::::::::::: XP_011 MLPMFGIMPSKKVASAYFKDFHLLLIGVIC 10 20 30 100 110 120 130 140 150 pF1KB7 LATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAV 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB7 VQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISS 100 110 120 130 140 150 220 pF1KB7 KVELEK------------------------------------------------------ :::::: XP_011 KVELEKEEEESNQQRVFTGSWVRKRMKLLLAYTLESHLLNKTLTFGLVIPQVKPFQDVPL 160 170 180 190 200 210 230 240 250 260 270 pF1KB7 --NSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKNSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRC 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB7 LNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQ 280 290 300 310 320 330 340 350 360 370 380 390 pF1KB7 KLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFL 340 350 360 370 380 390 400 410 420 430 440 450 pF1KB7 IPAKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPAKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWI 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB7 GNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIP 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB7 STLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFD 520 530 540 550 560 570 580 590 pF1KB7 LYTYPSWAPAMSNETMP ::::::::::::::::: XP_011 LYTYPSWAPAMSNETMP 580 >>XP_016868043 (OMIM: 606193) PREDICTED: solute carrier (608 aa) initn: 2732 init1: 2535 opt: 2543 Z-score: 3017.8 bits: 568.4 E(85289): 2.3e-161 Smith-Waterman score: 3435; 84.8% identity (84.8% similar) in 651 aa overlap (1-595:1-608) 10 20 30 40 50 60 pF1KB7 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL ::::::::::::::::::::::::::::::::: XP_016 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTK--------------------------- 10 20 30 70 80 90 100 110 120 pF1KB7 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP :::::::::::::::::::::::::::::::::::::::::::: XP_016 ----------------VASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 40 50 60 70 130 140 150 160 170 180 pF1KB7 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 80 90 100 110 120 130 190 200 210 220 pF1KB7 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEK-------------------- :::::::::::::::::::::::::::::::::::::::: XP_016 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKEEEESNQQRVFTGSWVRKRM 140 150 160 170 180 190 230 240 pF1KB7 ------------------------------------NSGMRTKYRTKKGHVTRKLTCLCI :::::::::::::::::::::::: XP_016 KLLLAYTLESHLLNKTLTFGLVIPQVKPFQDVPLSKNSGMRTKYRTKKGHVTRKLTCLCI 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB7 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB7 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR 320 330 340 350 360 370 370 380 390 400 410 420 pF1KB7 DPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITW 380 390 400 410 420 430 430 440 450 460 470 480 pF1KB7 KEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSL 440 450 460 470 480 490 490 500 510 520 530 540 pF1KB7 TEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGH 500 510 520 530 540 550 550 560 570 580 590 pF1KB7 LKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP 560 570 580 590 600 >>XP_011514817 (OMIM: 606193) PREDICTED: solute carrier (651 aa) initn: 2535 init1: 2535 opt: 2543 Z-score: 3017.4 bits: 568.5 E(85289): 2.5e-161 Smith-Waterman score: 3662; 91.1% identity (91.1% similar) in 627 aa overlap (25-595:25-651) 10 20 30 40 50 60 pF1KB7 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL :::::::::::::::::::::::::::::::::::: XP_011 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 130 140 150 160 170 180 190 200 210 220 pF1KB7 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEK-------------------- :::::::::::::::::::::::::::::::::::::::: XP_011 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKEEEESNQQRVFTGSWVRKRM 190 200 210 220 230 240 230 240 pF1KB7 ------------------------------------NSGMRTKYRTKKGHVTRKLTCLCI :::::::::::::::::::::::: XP_011 KLLLAYTLESHLLNKTLTFGLVIPQVKPFQDVPLSKNSGMRTKYRTKKGHVTRKLTCLCI 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB7 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB7 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB7 DPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITW 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB7 KEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSL 490 500 510 520 530 540 490 500 510 520 530 540 pF1KB7 TEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGH 550 560 570 580 590 600 550 560 570 580 590 pF1KB7 LKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP 610 620 630 640 650 >>XP_011514821 (OMIM: 606193) PREDICTED: solute carrier (340 aa) initn: 1437 init1: 1437 opt: 1437 Z-score: 1709.3 bits: 325.5 E(85289): 1.8e-88 Smith-Waterman score: 1616; 82.2% identity (82.2% similar) in 331 aa overlap (1-275:1-331) 10 20 30 40 50 60 pF1KB7 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 130 140 150 160 170 180 190 200 210 220 pF1KB7 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEK-------------------- :::::::::::::::::::::::::::::::::::::::: XP_011 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKEEEESNQQRVFTGSWVRKRM 190 200 210 220 230 240 230 240 pF1KB7 ------------------------------------NSGMRTKYRTKKGHVTRKLTCLCI :::::::::::::::::::::::: XP_011 KLLLAYTLESHLLNKTLTFGLVIPQVKPFQDVPLSKNSGMRTKYRTKKGHVTRKLTCLCI 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB7 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ ::::::::::::::::::::::::::: : XP_011 AYSSTIGGLTTITGTSTNLIFAEYFNTTSIDLQTFLYTEN 310 320 330 340 310 320 330 340 350 360 pF1KB7 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR >>XP_011514820 (OMIM: 606193) PREDICTED: solute carrier (346 aa) initn: 1763 init1: 1437 opt: 1437 Z-score: 1709.2 bits: 325.5 E(85289): 1.8e-88 Smith-Waterman score: 1625; 82.0% identity (82.3% similar) in 333 aa overlap (1-277:1-333) 10 20 30 40 50 60 pF1KB7 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 130 140 150 160 170 180 190 200 210 220 pF1KB7 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEK-------------------- :::::::::::::::::::::::::::::::::::::::: XP_011 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKEEEESNQQRVFTGSWVRKRM 190 200 210 220 230 240 230 240 pF1KB7 ------------------------------------NSGMRTKYRTKKGHVTRKLTCLCI :::::::::::::::::::::::: XP_011 KLLLAYTLESHLLNKTLTFGLVIPQVKPFQDVPLSKNSGMRTKYRTKKGHVTRKLTCLCI 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB7 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ ::::::::::::::::::::::::::: .: : XP_011 AYSSTIGGLTTITGTSTNLIFAEYFNTFHPHRRGDRTRHVHQEAEI 310 320 330 340 310 320 330 340 350 360 pF1KB7 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR >>XP_016868044 (OMIM: 606193) PREDICTED: solute carrier (352 aa) initn: 1437 init1: 1437 opt: 1437 Z-score: 1709.1 bits: 325.5 E(85289): 1.9e-88 Smith-Waterman score: 1614; 82.9% identity (82.9% similar) in 327 aa overlap (1-271:1-327) 10 20 30 40 50 60 pF1KB7 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 130 140 150 160 170 180 190 200 210 220 pF1KB7 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEK-------------------- :::::::::::::::::::::::::::::::::::::::: XP_016 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKEEEESNQQRVFTGSWVRKRM 190 200 210 220 230 240 230 240 pF1KB7 ------------------------------------NSGMRTKYRTKKGHVTRKLTCLCI :::::::::::::::::::::::: XP_016 KLLLAYTLESHLLNKTLTFGLVIPQVKPFQDVPLSKNSGMRTKYRTKKGHVTRKLTCLCI 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB7 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ ::::::::::::::::::::::::::: XP_016 AYSSTIGGLTTITGTSTNLIFAEYFNTSGRKGQSKMVEYRAPWIVPRARTPI 310 320 330 340 350 >>XP_011514818 (OMIM: 606193) PREDICTED: solute carrier (617 aa) initn: 2858 init1: 1437 opt: 1437 Z-score: 1705.3 bits: 325.6 E(85289): 3e-88 Smith-Waterman score: 3500; 86.2% identity (86.2% similar) in 651 aa overlap (1-595:1-617) 10 20 30 40 50 60 pF1KB7 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHG 130 140 150 160 170 180 190 200 210 220 pF1KB7 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEK-------------------- :::::::::::::::::::::::::::::::::::::::: XP_011 LEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKEEEESNQQRVFTGSWVRKRM 190 200 210 220 230 240 230 240 pF1KB7 ------------------------------------NSGMRTKYRTKKGHVTRKLTCLCI :::::::::::::::::::::::: XP_011 KLLLAYTLESHLLNKTLTFGLVIPQVKPFQDVPLSKNSGMRTKYRTKKGHVTRKLTCLCI 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB7 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQ 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB7 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSR ::::::::::::::::::::::::::::::::::::::::: XP_011 WLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRY------------------- 370 380 390 400 370 380 390 400 410 420 pF1KB7 DPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITW ::::::::::::::::::::::::::::::::::::::::::::: XP_011 ---------------PGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITW 410 420 430 440 430 440 450 460 470 480 pF1KB7 KEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSL 450 460 470 480 490 500 490 500 510 520 530 540 pF1KB7 TEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGH 510 520 530 540 550 560 550 560 570 580 590 pF1KB7 LKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP 570 580 590 600 610 >>NP_036582 (OMIM: 604309) solute carrier family 13 memb (626 aa) initn: 1797 init1: 763 opt: 1404 Z-score: 1666.0 bits: 318.4 E(85289): 4.7e-86 Smith-Waterman score: 1969; 48.7% identity (76.4% similar) in 618 aa overlap (1-586:1-617) 10 20 30 40 50 60 pF1KB7 MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTAL : ... .: :..:.:: . :.:::::.. ..:: :::.:.:.:..:..::.::...:: NP_036 MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 LPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNP .:... :.::.. :..::. :::. :::.::::.:...:::::::::::.::.:.:..: NP_036 VPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKP 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 AWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEV---------EATQMT . : : :: :..::::::::::.::::::.:::.:....:: : :: .. NP_036 GMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPIS 130 140 150 160 170 180 180 190 200 210 pF1KB7 YFNGSTNHGLEI----DES-------VNGHEINERKEKTKPVPGYNNDTGKISSKVELE- ... .::. .:: ......: :.:. :. :: . . . NP_036 LDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB7 -------KNSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTR ... . :::... .. : : :.::.:::::::: ::::.::: :.::.. NP_036 QVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB7 YPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQKACAEV :: . .:::.:: :::: .::.:..::.:..::::: :::: . .: : .... .: NP_036 YPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEK 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB7 -IKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALL :..::.::: : : :.:: .::.:..:::.:.:::::::...: : :. ::.::... NP_036 RIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFF-EKKGYRTDATVSVF 370 380 390 400 410 400 410 420 430 440 pF1KB7 IGLLFFLIPAKTLT---KTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADG .:.:.:::::: :. .. .. :.::::.::. :::.:.::::::.:::.: NP_036 LGFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASG 420 430 440 450 460 470 450 460 470 480 490 500 pF1KB7 CEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAI . :::: ::::.. :.::: : . :.. ..:. .:: .:::::::.::::: :.:.. NP_036 SKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETL 480 490 500 510 520 530 510 520 530 540 550 560 pF1KB7 HVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLG :.:::: ::: :.: ::: .:::.:::::::::::: .. ::::::::::..:...::.. NP_036 HINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVA 540 550 560 570 580 590 570 580 590 pF1KB7 ICTWIVPMFDLYTYPSWAPAMSNETMP : :: : .: : :::.:: NP_036 INTWGVSLFHLDTYPAWARVSNITDQA 600 610 620 595 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:44:50 2016 done: Sat Nov 5 09:44:51 2016 Total Scan time: 9.700 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]