FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7229, 373 aa 1>>>pF1KB7229 373 - 373 aa - 373 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2411+/-0.000379; mu= 17.1015+/- 0.023 mean_var=66.9267+/-13.790, 0's: 0 Z-trim(113.9): 48 B-trim: 1365 in 2/51 Lambda= 0.156774 statistics sampled from 23475 (23524) to 23475 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.276), width: 16 Scan time: 8.000 The best scores are: opt bits E(85289) NP_009086 (OMIM: 182889) zona pellucida sperm-bind ( 373) 2540 583.4 2.9e-166 NP_001103824 (OMIM: 182889) zona pellucida sperm-b ( 424) 2540 583.4 3.2e-166 XP_016868075 (OMIM: 182889) PREDICTED: zona pelluc ( 226) 1538 356.6 3.2e-98 NP_036362 (OMIM: 600587) POM121 and ZP3 fusion pro ( 187) 759 180.4 3e-45 NP_694537 (OMIM: 600587) POM121 and ZP3 fusion pro ( 115) 269 69.4 4.6e-12 NP_003451 (OMIM: 182888) zona pellucida sperm-bind ( 745) 225 60.0 2.1e-08 XP_011544244 (OMIM: 182888) PREDICTED: zona pelluc ( 756) 225 60.0 2.1e-08 NP_689848 (OMIM: 609330) oncoprotein-induced trans ( 545) 213 57.2 1.1e-07 NP_001277033 (OMIM: 182888) zona pellucida sperm-b ( 736) 191 52.3 4.3e-06 NP_997224 (OMIM: 195000,615774) zona pellucida spe ( 638) 176 48.8 4e-05 NP_071317 (OMIM: 616644) CUB and zona pellucida-li ( 607) 175 48.6 4.5e-05 XP_011537717 (OMIM: 601969) PREDICTED: deleted in (1766) 177 49.3 8e-05 XP_011537716 (OMIM: 601969) PREDICTED: deleted in (1783) 177 49.3 8e-05 NP_004397 (OMIM: 601969) deleted in malignant brai (1785) 177 49.3 8e-05 XP_011543154 (OMIM: 195000,615774) PREDICTED: zona ( 345) 168 46.9 8.6e-05 XP_011543155 (OMIM: 195000,615774) PREDICTED: zona ( 345) 168 46.9 8.6e-05 XP_016871287 (OMIM: 601969) PREDICTED: deleted in (1990) 177 49.4 8.8e-05 XP_011537715 (OMIM: 601969) PREDICTED: deleted in (2282) 177 49.4 9.8e-05 NP_060049 (OMIM: 601969) deleted in malignant brai (2403) 177 49.4 0.0001 XP_011537713 (OMIM: 601969) PREDICTED: deleted in (2403) 177 49.4 0.0001 XP_011537712 (OMIM: 601969) PREDICTED: deleted in (2411) 177 49.4 0.0001 XP_011537709 (OMIM: 601969) PREDICTED: deleted in (2411) 177 49.4 0.0001 XP_011537711 (OMIM: 601969) PREDICTED: deleted in (2411) 177 49.4 0.0001 XP_011537710 (OMIM: 601969) PREDICTED: deleted in (2411) 177 49.4 0.0001 NP_001307573 (OMIM: 601969) deleted in malignant b (2412) 177 49.4 0.0001 XP_011537705 (OMIM: 601969) PREDICTED: deleted in (2413) 177 49.4 0.0001 XP_011537704 (OMIM: 601969) PREDICTED: deleted in (2413) 177 49.4 0.0001 NP_015568 (OMIM: 601969) deleted in malignant brai (2413) 177 49.4 0.0001 XP_011537707 (OMIM: 601969) PREDICTED: deleted in (2413) 177 49.4 0.0001 XP_011537703 (OMIM: 601969) PREDICTED: deleted in (2413) 177 49.4 0.0001 XP_011537702 (OMIM: 601969) PREDICTED: deleted in (2434) 177 49.4 0.0001 XP_011537701 (OMIM: 601969) PREDICTED: deleted in (2510) 177 49.4 0.00011 XP_006717728 (OMIM: 601969) PREDICTED: deleted in (2510) 177 49.4 0.00011 XP_011537700 (OMIM: 601969) PREDICTED: deleted in (2521) 177 49.4 0.00011 XP_011537698 (OMIM: 601969) PREDICTED: deleted in (2526) 177 49.4 0.00011 XP_006717723 (OMIM: 601969) PREDICTED: deleted in (2526) 177 49.4 0.00011 XP_011537694 (OMIM: 601969) PREDICTED: deleted in (2532) 177 49.4 0.00011 XP_011537695 (OMIM: 601969) PREDICTED: deleted in (2532) 177 49.4 0.00011 XP_011537696 (OMIM: 601969) PREDICTED: deleted in (2532) 177 49.4 0.00011 XP_011537697 (OMIM: 601969) PREDICTED: deleted in (2532) 177 49.4 0.00011 XP_011537692 (OMIM: 601969) PREDICTED: deleted in (2532) 177 49.4 0.00011 XP_011537693 (OMIM: 601969) PREDICTED: deleted in (2532) 177 49.4 0.00011 XP_011537691 (OMIM: 601969) PREDICTED: deleted in (2541) 177 49.4 0.00011 XP_011537690 (OMIM: 601969) PREDICTED: deleted in (2542) 177 49.4 0.00011 >>NP_009086 (OMIM: 182889) zona pellucida sperm-binding (373 aa) initn: 2540 init1: 2540 opt: 2540 Z-score: 3106.0 bits: 583.4 E(85289): 2.9e-166 Smith-Waterman score: 2540; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373) 10 20 30 40 50 60 pF1KB7 MVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 YSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 YSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 FSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 TIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 DPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 DPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 RHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSVVLLGVGLAVVVSLTLTAVILVLTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSVVLLGVGLAVVVSLTLTAVILVLTR 310 320 330 340 350 360 370 pF1KB7 RCRTASHPVSASE ::::::::::::: NP_009 RCRTASHPVSASE 370 >>NP_001103824 (OMIM: 182889) zona pellucida sperm-bindi (424 aa) initn: 2540 init1: 2540 opt: 2540 Z-score: 3105.2 bits: 583.4 E(85289): 3.2e-166 Smith-Waterman score: 2540; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:52-424) 10 20 30 pF1KB7 MVMVSKDLFGTGKLIRAADLTLGPEACEPL :::::::::::::::::::::::::::::: NP_001 PQPLWLLQGGASHPETSVQPVLVECQEATLMVMVSKDLFGTGKLIRAADLTLGPEACEPL 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB7 VSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECR 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB7 YPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAE 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB7 IHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB7 QFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQC 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB7 CNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWAL 330 340 350 360 370 380 340 350 360 370 pF1KB7 PSDTSVVLLGVGLAVVVSLTLTAVILVLTRRCRTASHPVSASE ::::::::::::::::::::::::::::::::::::::::::: NP_001 PSDTSVVLLGVGLAVVVSLTLTAVILVLTRRCRTASHPVSASE 390 400 410 420 >>XP_016868075 (OMIM: 182889) PREDICTED: zona pellucida (226 aa) initn: 1538 init1: 1538 opt: 1538 Z-score: 1884.4 bits: 356.6 E(85289): 3.2e-98 Smith-Waterman score: 1538; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KB7 MVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 YSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 TIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQ :::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNM 190 200 210 220 250 260 270 280 290 300 pF1KB7 DPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNR >>NP_036362 (OMIM: 600587) POM121 and ZP3 fusion protein (187 aa) initn: 759 init1: 759 opt: 759 Z-score: 933.4 bits: 180.4 E(85289): 3e-45 Smith-Waterman score: 759; 96.4% identity (98.2% similar) in 110 aa overlap (188-297:77-186) 160 170 180 190 200 210 pF1KB7 PLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVF :::::::::::::::::::::::::::::: NP_036 VLSALKEKKKKRTVEEEDQIFLDGQENKRSCLVDGLTDASSAFKVPRPGPDTLQFTVDVF 50 60 70 80 90 100 220 230 240 250 260 270 pF1KB7 HFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCG :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: NP_036 HFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGLADICQCCNKGDCG 110 120 130 140 150 160 280 290 300 310 320 330 pF1KB7 TPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSVV :::::::::.:.:::: ::: NP_036 TPSHSRRQPRVVSQWSTSASL 170 180 >>NP_694537 (OMIM: 600587) POM121 and ZP3 fusion protein (115 aa) initn: 269 init1: 269 opt: 269 Z-score: 337.6 bits: 69.4 E(85289): 4.6e-12 Smith-Waterman score: 269; 100.0% identity (100.0% similar) in 39 aa overlap (188-226:77-115) 160 170 180 190 200 210 pF1KB7 PLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVF :::::::::::::::::::::::::::::: NP_694 VLSALKEKKKKRTVEEEDQIFLDGQENKRSCLVDGLTDASSAFKVPRPGPDTLQFTVDVF 50 60 70 80 90 100 220 230 240 250 260 270 pF1KB7 HFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCG ::::::::: NP_694 HFANDSRNM 110 >>NP_003451 (OMIM: 182888) zona pellucida sperm-binding (745 aa) initn: 112 init1: 112 opt: 225 Z-score: 271.8 bits: 60.0 E(85289): 2.1e-08 Smith-Waterman score: 225; 21.8% identity (55.6% similar) in 252 aa overlap (20-257:396-638) 10 20 30 40 pF1KB7 MVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECG : .: .:.:. ... .:::.. :. :: NP_003 IVTGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIPLNGCG 370 380 390 400 410 420 50 60 70 80 90 100 pF1KB7 NSMQVTDDALVYSTFL--LHDPRPVGNLSIVRTNRAEIPIECRYPRQG---NVSSQAILP . .. :: .:: . . : : ...: : .. .. ..: : :. :.. ... : NP_003 TRYKFEDDKVVYENEIHALWTDFPPSKIS--RDSEFRMTVKCSYSRNDMLLNINVESLTP 430 440 450 460 470 480 110 120 130 140 150 160 pF1KB7 TWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVD . :. .. ... .. .. . : . ...... . . ..: .: NP_003 PVASVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLD 490 500 510 520 530 540 170 180 190 200 210 pF1KB7 HCVATPTPDQNASP-YHTIVDFHGCLVDGLTDASSAFKVPRPG----PDTLQ-FTVDVFH : :: : : .. : ....:: :: : : . ...:. : . :: : : . .: NP_003 DCWATSTMDPDSFPQWNVVVD--GCAYD-LDNYQTTFH-PVGSSVTHPDHYQRFDMKAFA 550 560 570 580 590 220 230 240 250 260 270 pF1KB7 FANDSR---NMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGD :..... ...:. : . . .:: . :: . : .: NP_003 FVSEAHVLSSLVYFHCSALIC-NRLSPD--SPLCSVTCPVSSRHRRATGATEAEKMTVSL 600 610 620 630 640 650 280 290 300 310 320 330 pF1KB7 CGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTS NP_003 PGPILLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGSRGAMDTKGHKTAGDVGSKA 660 670 680 690 700 710 >>XP_011544244 (OMIM: 182888) PREDICTED: zona pellucida (756 aa) initn: 112 init1: 112 opt: 225 Z-score: 271.7 bits: 60.0 E(85289): 2.1e-08 Smith-Waterman score: 225; 21.8% identity (55.6% similar) in 252 aa overlap (20-257:396-638) 10 20 30 40 pF1KB7 MVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECG : .: .:.:. ... .:::.. :. :: XP_011 IVTGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIPLNGCG 370 380 390 400 410 420 50 60 70 80 90 100 pF1KB7 NSMQVTDDALVYSTFL--LHDPRPVGNLSIVRTNRAEIPIECRYPRQG---NVSSQAILP . .. :: .:: . . : : ...: : .. .. ..: : :. :.. ... : XP_011 TRYKFEDDKVVYENEIHALWTDFPPSKIS--RDSEFRMTVKCSYSRNDMLLNINVESLTP 430 440 450 460 470 480 110 120 130 140 150 160 pF1KB7 TWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVD . :. .. ... .. .. . : . ...... . . ..: .: XP_011 PVASVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLD 490 500 510 520 530 540 170 180 190 200 210 pF1KB7 HCVATPTPDQNASP-YHTIVDFHGCLVDGLTDASSAFKVPRPG----PDTLQ-FTVDVFH : :: : : .. : ....:: :: : : . ...:. : . :: : : . .: XP_011 DCWATSTMDPDSFPQWNVVVD--GCAYD-LDNYQTTFH-PVGSSVTHPDHYQRFDMKAFA 550 560 570 580 590 220 230 240 250 260 270 pF1KB7 FANDSR---NMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGD :..... ...:. : . . .:: . :: . : .: XP_011 FVSEAHVLSSLVYFHCSALIC-NRLSPD--SPLCSVTCPVSSRHRREAKHKLDHLSPATG 600 610 620 630 640 650 280 290 300 310 320 330 pF1KB7 CGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTS XP_011 ATEAEKMTVSLPGPILLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGSRGAMDTKG 660 670 680 690 700 710 >>NP_689848 (OMIM: 609330) oncoprotein-induced transcrip (545 aa) initn: 72 init1: 72 opt: 213 Z-score: 259.1 bits: 57.2 E(85289): 1.1e-07 Smith-Waterman score: 213; 25.2% identity (59.6% similar) in 250 aa overlap (13-249:280-513) 10 20 30 40 pF1KB7 MVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFE .:. . .: : .:. :: :. . : NP_689 PRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRG-VSNGTHVNILF- 250 260 270 280 290 300 50 60 70 80 90 pF1KB7 VGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLS---IVRTNRAEIPIECRYPRQGNVSS .:. ::. ..:..: .: :... :. . . : :.::.. ::. :..:: ..: NP_689 -SLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTIS- 310 320 330 340 350 360 100 110 120 130 140 150 pF1KB7 QAILPTWLPFRTTVFSEEK--LTFSLRLMEENWNAEKRS---PTFHLGDAAHLQAE--IH .. .:. ..:... . :.:.....: : ::..: :. .. : .: NP_689 EGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVH 370 380 390 400 410 420 160 170 180 190 200 210 pF1KB7 TGSHVPLRLFVDHCVATPTPD-QNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTL- ... :. .:. : :::: ... :. : : ::. : :. . . . : : : NP_689 VSG---LESLVESCFATPTSKIDEVLKYYLIRD--GCVSD---DSVKQY-TSR---DHLA 430 440 450 460 470 220 230 240 250 260 pF1KB7 -QFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQ .: : ::.:.. ... ... :.. : . .. .. ..: NP_689 KHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQT 480 490 500 510 520 530 270 280 290 300 310 320 pF1KB7 CCNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWA NP_689 LTGGPIRIDWED 540 >>NP_001277033 (OMIM: 182888) zona pellucida sperm-bindi (736 aa) initn: 112 init1: 112 opt: 191 Z-score: 230.3 bits: 52.3 E(85289): 4.3e-06 Smith-Waterman score: 191; 21.7% identity (53.4% similar) in 249 aa overlap (20-257:396-629) 10 20 30 40 pF1KB7 MVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECG : .: .:.:. ... .:::.. :. :: NP_001 IVTGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIPLNGCG 370 380 390 400 410 420 50 60 70 80 90 100 pF1KB7 NSMQVTDDALVYSTFL--LHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWL . .. :: .:: . . : : ...: : . : : :.. ... : NP_001 TRYKFEDDKVVYENEIHALWTDFPPSKIS--RDS------EFRNDMLLNINVESLTPPVA 430 440 450 460 470 110 120 130 140 150 160 pF1KB7 PFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCV . :. .. ... .. .. . : . ...... . . ..: .: : NP_001 SVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCW 480 490 500 510 520 530 170 180 190 200 210 220 pF1KB7 ATPTPDQNASP-YHTIVDFHGCLVDGLTDASSAFKVPRPG----PDTLQ-FTVDVFHFAN :: : : .. : ....:: :: : : . ...:. : . :: : : . .: :.. NP_001 ATSTMDPDSFPQWNVVVD--GCAYD-LDNYQTTFH-PVGSSVTHPDHYQRFDMKAFAFVS 540 550 560 570 580 590 230 240 250 260 270 pF1KB7 DSR---NMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGT ... ...:. : . . .:: . :: . : .: NP_001 EAHVLSSLVYFHCSALIC-NRLSPD--SPLCSVTCPVSSRHRRATGATEAEKMTVSLPGP 600 610 620 630 640 650 280 290 300 310 320 330 pF1KB7 PSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSVVL NP_001 ILLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGSRGAMDTKGHKTAGDVGSKAVAA 660 670 680 690 700 710 >>NP_997224 (OMIM: 195000,615774) zona pellucida sperm-b (638 aa) initn: 87 init1: 87 opt: 176 Z-score: 212.9 bits: 48.8 E(85289): 4e-05 Smith-Waterman score: 190; 24.2% identity (53.2% similar) in 252 aa overlap (1-231:287-529) 10 20 pF1KB7 MVMVSKDLFGTGKLIRAA-DLTLGPEACEP ...::... : .. : :. .: .: : NP_997 QAGCCYDNTREVPCYYGNTATVQCFRDGYFVLVVSQEMALTHRITLANIHLAYAPTSCSP 260 270 280 290 300 310 30 40 50 60 70 80 pF1KB7 LVSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFL---LHDPR-PVGNLSIVRTNRAEI .. :: : : : .::..:::. : :.: ..: .: . : : ::.: . .. NP_997 --TQHTEAFVVFYFPLTHCGTTMQVAGDQLIYENWLVSGIHIQKGPQG--SITRDSTFQL 320 330 340 350 360 370 90 100 110 120 130 140 pF1KB7 PIECRYPRQGNVSSQA-ILPTWLPFRTTVFSEEKLTFSLRLMEE----NWNAEKRSPTFH ..: . . . :: :.: : . . . : . ::. .. .. .: : . NP_997 HVRCVFNASDFLPIQASIFPP--PSPAPMTQPGPLRLELRIAKDETFSSYYGEDDYPIVR 380 390 400 410 420 430 150 160 170 180 190 pF1KB7 L-GDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSA : . .:..... . : :.. .: ..:. . .: :.. :: : :. . NP_997 LLREPVHVEVRLLQRTDPNLVLLLHQCWGAPSANPFQQPQWPILS-DGCPFKG--DSYRT 440 450 460 470 480 200 210 220 230 240 pF1KB7 FKVPRPGPDTLQ-----FTVDVFHFANDS-----RNMIYITCHLKVTLAEQDPDELNKAC : : .: ::: .: . ... :...:. : NP_997 QMVALDGATPFQSHYQRFTVATFALLDSGSQRALRGLVYLFCSTSACHTSGLETCSTACS 490 500 510 520 530 540 250 260 270 280 290 300 pF1KB7 SFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADV NP_997 TGTTRQRRSSGHRNDTARPQDIVSSPGPVGFEDSYGQEPTLGPTDSNGNSSLRPLLWAVL 550 560 570 580 590 600 373 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:07:19 2016 done: Fri Nov 4 06:07:20 2016 Total Scan time: 8.000 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]