FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7231, 434 aa
1>>>pF1KB7231 434 - 434 aa - 434 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9417+/-0.000409; mu= 19.1423+/- 0.025
mean_var=63.3169+/-12.487, 0's: 0 Z-trim(111.4): 65 B-trim: 0 in 0/55
Lambda= 0.161181
statistics sampled from 19970 (20040) to 19970 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.235), width: 16
Scan time: 7.410
The best scores are: opt bits E(85289)
NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 2691 634.8 1.3e-181
NP_006079 (OMIM: 602660) tubulin beta-4B chain [Ho ( 445) 2533 598.0 1.6e-170
NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 2515 593.8 2.8e-169
NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 2513 593.4 3.9e-169
NP_001276058 (OMIM: 602662) tubulin beta-4A chain ( 444) 2512 593.2 4.6e-169
NP_006078 (OMIM: 602662) tubulin beta-4A chain iso ( 444) 2512 593.2 4.6e-169
NP_001276056 (OMIM: 602662) tubulin beta-4A chain ( 489) 2512 593.2 4.9e-169
NP_001276052 (OMIM: 602662) tubulin beta-4A chain ( 495) 2512 593.2 5e-169
NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 2498 589.9 4.4e-168
NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 2423 572.5 7.8e-163
NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 2417 571.1 2.1e-162
NP_001290453 (OMIM: 615103) tubulin beta-6 chain i ( 446) 2407 568.7 1e-161
NP_115914 (OMIM: 615103) tubulin beta-6 chain isof ( 446) 2407 568.7 1e-161
XP_011517761 (OMIM: 616768,616780) PREDICTED: tubu ( 372) 2244 530.8 2.3e-150
NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 2225 526.4 5.2e-149
NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 2154 509.9 5.3e-144
NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 2126 503.3 4.2e-142
NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 2126 503.3 4.2e-142
NP_001276060 (OMIM: 602662) tubulin beta-4A chain ( 372) 2116 501.0 2.1e-141
NP_001276059 (OMIM: 602662) tubulin beta-4A chain ( 372) 2116 501.0 2.1e-141
NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 2063 488.7 1.1e-137
NP_001290456 (OMIM: 615103) tubulin beta-6 chain i ( 374) 2053 486.4 5.4e-137
XP_016883574 (OMIM: 612901,613112) PREDICTED: tubu ( 429) 2022 479.2 8.9e-135
XP_016871682 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 1983 470.1 3.9e-132
XP_016871681 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 1983 470.1 3.9e-132
NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 1983 470.1 4.1e-132
NP_001290455 (OMIM: 615103) tubulin beta-6 chain i ( 409) 1929 457.6 2.8e-128
NP_001290457 (OMIM: 615103) tubulin beta-6 chain i ( 381) 1927 457.1 3.6e-128
XP_011517762 (OMIM: 616768,616780) PREDICTED: tubu ( 291) 1630 387.9 1.8e-107
NP_001290458 (OMIM: 615103) tubulin beta-6 chain i ( 300) 1608 382.8 6.4e-106
NP_001290459 (OMIM: 615103) tubulin beta-6 chain i ( 300) 1608 382.8 6.4e-106
NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 957 231.6 3.3e-60
NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 952 230.4 7.3e-60
NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 949 229.7 1.2e-59
NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 949 229.7 1.2e-59
NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain ( 450) 946 229.0 1.9e-59
NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 935 226.4 1.1e-58
NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 916 222.0 2.4e-57
NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 912 221.1 4.6e-57
NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 906 219.7 1.2e-56
NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 868 210.8 5.2e-54
NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 810 197.3 5.6e-50
NP_001280142 (OMIM: 156610,191130,615771) tubulin ( 242) 689 169.1 1.1e-41
NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 575 142.7 1.8e-33
XP_016860313 (OMIM: 191110,616208) PREDICTED: tubu ( 295) 534 133.1 9.5e-31
NP_057346 (OMIM: 607345) tubulin epsilon chain [Ho ( 475) 512 128.1 4.8e-29
NP_001290454 (OMIM: 615103) tubulin beta-6 chain i ( 104) 486 121.6 9.5e-28
XP_016879942 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 480 120.5 5.8e-27
XP_011522916 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 480 120.5 5.8e-27
XP_016880205 (OMIM: 607344) PREDICTED: tubulin del ( 375) 466 117.3 6.6e-26
>>NP_817124 (OMIM: 616768,616780) tubulin beta-8 chain [ (444 aa)
initn: 2359 init1: 2359 opt: 2691 Z-score: 3381.2 bits: 634.8 E(85289): 1.3e-181
Smith-Waterman score: 2691; 93.5% identity (96.5% similar) in 431 aa overlap (1-430:1-431)
10 20 30 40 50 60
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV
:::.:::: ::::::::::::::::::::::::::::::::::::::::...::::::::
NP_817 MREIVLTQIGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVYYNEASGGRYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SRAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGAELTESVMDVV
:::::::::::::::::::::::::::::: :::::::::::.::::::: :::::::
NP_817 PRAVLVDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGAELMESVMDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSILLLPKVSDTVV
:::::::::::::::::::::::::::::::.::: ::::::::::.::: ::::::::
NP_817 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_817 EPYNATLSVHQLIENADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CFPDQLNADLRKLAMNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
:: ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_817 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AARDPRHGRYLTAAAIFQGRMPMREVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWG
:: ::::::::::::::.::::::::::::::::::::::::::.::::::::::::: :
NP_817 AACDPRHGRYLTAAAIFRGRMPMREVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 LKMSVTFTGNNTAVQEL-KRVSEQFTATFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
::::.:: :::::.::: ::::::::: ::::::::::::::::::::::::::::::::
NP_817 LKMSATFIGNNTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
420 430
pF1KB7 EYQQYQDATAEGGGV
:::::::::::
NP_817 EYQQYQDATAEEEEDEEYAEEEVA
430 440
>>NP_006079 (OMIM: 602660) tubulin beta-4B chain [Homo s (445 aa)
initn: 2200 init1: 2200 opt: 2533 Z-score: 3182.6 bits: 598.0 E(85289): 1.6e-170
Smith-Waterman score: 2533; 85.9% identity (94.5% similar) in 434 aa overlap (1-433:1-434)
10 20 30 40 50 60
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV
:::.: :.:::::::::::::::::::.:: .::::::: ::::::::...::.::.::
NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SRAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGAELTESVMDVV
::::::::::::::::::::::.::::::. : :::::::::.:::::::..::.:::
NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSILLLPKVSDTVV
::::::::::::::::::::::::::::::::::: :::::::.::.:.. ::::::::
NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL
::::::::::::.::.:::.::::::::::: ::::: ::::::::::::::::::::::
NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CFPDQLNADLRKLAMNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
:: ::::::::::.::::::::::::::::::::::::::::::: :::::::::::::
NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AARDPRHGRYLTAAAIFQGRMPMREVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWG
:: :::::::::.::.:.::: :.::::::.:.:.::::::..:.::::::::::::: :
NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 LKMSVTFTGNNTAVQEL-KRVSEQFTATFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
::::.:: ::.::.::: ::.:::::: ::::::::::::::::::::::::::::::::
NP_006 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
420 430
pF1KB7 EYQQYQDATAEGGGV
::::::::::: :
NP_006 EYQQYQDATAEEEGEFEEEAEEEVA
430 440
>>NP_821133 (OMIM: 156610,191130,615771) tubulin beta ch (444 aa)
initn: 2184 init1: 2184 opt: 2515 Z-score: 3160.0 bits: 593.8 E(85289): 2.8e-169
Smith-Waterman score: 2515; 85.4% identity (94.9% similar) in 431 aa overlap (1-430:1-431)
10 20 30 40 50 60
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV
:::.: :.:::::::::::::::::::.:: .::::::: :::.::.:...::.::.::
NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SRAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGAELTESVMDVV
::.:::::::::::::::::::.::::::. : :::::::::.:::::::..::.:::
NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSILLLPKVSDTVV
::::::::::::::::::::::::::::::::::: :::::::.::.:.. ::::::::
NP_821 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL
::::::::::::.::.:::.::::::::::: ::::: ::::::::::::::::::::::
NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CFPDQLNADLRKLAMNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
:: ::::::::::.::::::::::::::::::::::::::::::: :::::.:::::::
NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AARDPRHGRYLTAAAIFQGRMPMREVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWG
:: :::::::::.::.:.::: :.::::::.:.:.::::::..:.::::::::::::: :
NP_821 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 LKMSVTFTGNNTAVQEL-KRVSEQFTATFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
:::.::: ::.::.::: ::.:::::: ::::::::::::::::::::::::::::::::
NP_821 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
420 430
pF1KB7 EYQQYQDATAEGGGV
:::::::::::
NP_821 EYQQYQDATAEEEEDFGEEAEEEA
430 440
>>NP_821080 (OMIM: 610031,612850) tubulin beta-2B chain (445 aa)
initn: 2508 init1: 2183 opt: 2513 Z-score: 3157.5 bits: 593.4 E(85289): 3.9e-169
Smith-Waterman score: 2513; 84.8% identity (94.5% similar) in 434 aa overlap (1-433:1-434)
10 20 30 40 50 60
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV
:::.: :.:::::::::::::::::::.:: .:.::::: ::::::::...::.:..::
NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SRAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGAELTESVMDVV
::.:::::::::::::::::::.::::::. : :::::::::.:::::::..::.:::
NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSILLLPKVSDTVV
:::.::::::::::::::::::::::::::::::: :::::::.::.:.. ::::::::
NP_821 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL
::::::::::::.::.:::.::::::::::: ::::: ::::::::::::::::::::::
NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CFPDQLNADLRKLAMNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
:: ::::::::::.::::::::::::::::::::::::::::::: ::::::::.::::
NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AARDPRHGRYLTAAAIFQGRMPMREVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWG
:: :::::::::.::::.::: :.::::::.:.:.::::::..:.::::::::::::: :
NP_821 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 LKMSVTFTGNNTAVQEL-KRVSEQFTATFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
::::.:: ::.::.::: ::.:::::: ::::::::::::::::::::::::::::::::
NP_821 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
420 430
pF1KB7 EYQQYQDATAEGGGV
::::::::::. :
NP_821 EYQQYQDATADEQGEFEEEEGEDEA
430 440
>>NP_001276058 (OMIM: 602662) tubulin beta-4A chain isof (444 aa)
initn: 2510 init1: 2176 opt: 2512 Z-score: 3156.3 bits: 593.2 E(85289): 4.6e-169
Smith-Waterman score: 2512; 85.2% identity (94.5% similar) in 433 aa overlap (1-432:1-433)
10 20 30 40 50 60
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV
:::.: :.:::::::::::::::::::.:: .::::::: ::::::::...::.:: ::
NP_001 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SRAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGAELTESVMDVV
::::::::::::::::::::::.::::::. : :::::::::.:::::::...:.:::
NP_001 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSILLLPKVSDTVV
::::::::::::::::::::::::::::::::::: ::.::::.::.:.. ::::::::
NP_001 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL
::::::::::::.::.:::.::::::::::: ::::: ::::::::::::::::::::::
NP_001 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CFPDQLNADLRKLAMNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
:: ::::::::::.::::::::::::::::::::::::::::::: :::::::::::::
NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AARDPRHGRYLTAAAIFQGRMPMREVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWG
:: :::::::::.::.:.::: :.::::::...:.::::::..:.::::::::::::: :
NP_001 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 LKMSVTFTGNNTAVQEL-KRVSEQFTATFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
:::..:: ::.::.::: ::.:::::: ::::::::::::::::::::::::::::::::
NP_001 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
420 430
pF1KB7 EYQQYQDATAEGGGV
::::::::::: :
NP_001 EYQQYQDATAEEGEFEEEAEEEVA
430 440
>>NP_006078 (OMIM: 602662) tubulin beta-4A chain isoform (444 aa)
initn: 2510 init1: 2176 opt: 2512 Z-score: 3156.3 bits: 593.2 E(85289): 4.6e-169
Smith-Waterman score: 2512; 85.2% identity (94.5% similar) in 433 aa overlap (1-432:1-433)
10 20 30 40 50 60
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV
:::.: :.:::::::::::::::::::.:: .::::::: ::::::::...::.:: ::
NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SRAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGAELTESVMDVV
::::::::::::::::::::::.::::::. : :::::::::.:::::::...:.:::
NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSILLLPKVSDTVV
::::::::::::::::::::::::::::::::::: ::.::::.::.:.. ::::::::
NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL
::::::::::::.::.:::.::::::::::: ::::: ::::::::::::::::::::::
NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CFPDQLNADLRKLAMNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
:: ::::::::::.::::::::::::::::::::::::::::::: :::::::::::::
NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AARDPRHGRYLTAAAIFQGRMPMREVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWG
:: :::::::::.::.:.::: :.::::::...:.::::::..:.::::::::::::: :
NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 LKMSVTFTGNNTAVQEL-KRVSEQFTATFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
:::..:: ::.::.::: ::.:::::: ::::::::::::::::::::::::::::::::
NP_006 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
420 430
pF1KB7 EYQQYQDATAEGGGV
::::::::::: :
NP_006 EYQQYQDATAEEGEFEEEAEEEVA
430 440
>>NP_001276056 (OMIM: 602662) tubulin beta-4A chain isof (489 aa)
initn: 2510 init1: 2176 opt: 2512 Z-score: 3155.7 bits: 593.2 E(85289): 4.9e-169
Smith-Waterman score: 2512; 85.2% identity (94.5% similar) in 433 aa overlap (1-432:46-478)
10 20 30
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAI
:::.: :.:::::::::::::::::::.:
NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB7 DSAGTYHGDSHLQLERINVHHHEASGGRYVSRAVLVDLEPGTMDSVRSGPFGQVFRPDNF
: .::::::: ::::::::...::.:: :: ::::::::::::::::::::::.::::::
NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB7 ISRQCGAGNNWAKGRYTEGAELTESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
. : :::::::::.:::::::...:.:::::::::::::::::::::::::::::::::
NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB7 LISKIWEEYPDRIINTLSILLLPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDI
::::: ::.::::.::.:.. ::::::::::::::::::::.::.:::.::::::::::
NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB7 CSRTLKLPTPTYGDLNHLVSATMSGVTTCLCFPDQLNADLRKLAMNMVPFPRLHFFMPGF
: ::::: :::::::::::::::::::::: :: ::::::::::.:::::::::::::::
NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB7 APLTSRGSQQYRALTVAELTQQMFDAKNMMAARDPRHGRYLTAAAIFQGRMPMREVDEQM
:::::::::::::::: ::::::::::::::: :::::::::.::.:.::: :.::::::
NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM
320 330 340 350 360 370
340 350 360 370 380
pF1KB7 FNIQDKNSSYFADWFPNNVKTAVCDIPPWGLKMSVTFTGNNTAVQEL-KRVSEQFTATFR
...:.::::::..:.::::::::::::: ::::..:: ::.::.::: ::.:::::: ::
NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR
380 390 400 410 420 430
390 400 410 420 430
pF1KB7 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEGGGV
::::::::::::::::::::::::::::::::::::::::: :
NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGEFEEEAEEEVA
440 450 460 470 480
>>NP_001276052 (OMIM: 602662) tubulin beta-4A chain isof (495 aa)
initn: 2510 init1: 2176 opt: 2512 Z-score: 3155.6 bits: 593.2 E(85289): 5e-169
Smith-Waterman score: 2512; 85.2% identity (94.5% similar) in 433 aa overlap (1-432:52-484)
10 20 30
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAI
:::.: :.:::::::::::::::::::.:
NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB7 DSAGTYHGDSHLQLERINVHHHEASGGRYVSRAVLVDLEPGTMDSVRSGPFGQVFRPDNF
: .::::::: ::::::::...::.:: :: ::::::::::::::::::::::.::::::
NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB7 ISRQCGAGNNWAKGRYTEGAELTESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
. : :::::::::.:::::::...:.:::::::::::::::::::::::::::::::::
NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB7 LISKIWEEYPDRIINTLSILLLPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDI
::::: ::.::::.::.:.. ::::::::::::::::::::.::.:::.::::::::::
NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB7 CSRTLKLPTPTYGDLNHLVSATMSGVTTCLCFPDQLNADLRKLAMNMVPFPRLHFFMPGF
: ::::: :::::::::::::::::::::: :: ::::::::::.:::::::::::::::
NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB7 APLTSRGSQQYRALTVAELTQQMFDAKNMMAARDPRHGRYLTAAAIFQGRMPMREVDEQM
:::::::::::::::: ::::::::::::::: :::::::::.::.:.::: :.::::::
NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM
330 340 350 360 370 380
340 350 360 370 380
pF1KB7 FNIQDKNSSYFADWFPNNVKTAVCDIPPWGLKMSVTFTGNNTAVQEL-KRVSEQFTATFR
...:.::::::..:.::::::::::::: ::::..:: ::.::.::: ::.:::::: ::
NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR
390 400 410 420 430 440
390 400 410 420 430
pF1KB7 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEGGGV
::::::::::::::::::::::::::::::::::::::::: :
NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGEFEEEAEEEVA
450 460 470 480 490
>>NP_001060 (OMIM: 615101,615763) tubulin beta-2A chain (445 aa)
initn: 2493 init1: 2168 opt: 2498 Z-score: 3138.7 bits: 589.9 E(85289): 4.4e-168
Smith-Waterman score: 2498; 84.6% identity (94.2% similar) in 434 aa overlap (1-433:1-434)
10 20 30 40 50 60
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV
:::.: :.:::::::::::::::::::.:: .:.::::: ::::::::...::.:..::
NP_001 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SRAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGAELTESVMDVV
::.:::::::::::::::::::.::::::. : :::::::::.:::::::..::.:::
NP_001 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSILLLPKVSDTVV
:::.::::::::::::::::::::::::::::::: :::::::.::.:.. ::::::::
NP_001 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL
::::::::::::.::.:::. :::::::::: ::::: ::::::::::::::::::::::
NP_001 EPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CFPDQLNADLRKLAMNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
:: ::::::::::.::::::::::::::::::::::::::::::: ::::::::.::::
NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AARDPRHGRYLTAAAIFQGRMPMREVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWG
:: :::::::::.::::.::: :.::::::.:.:.::::::..:.::::::::::::: :
NP_001 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 LKMSVTFTGNNTAVQEL-KRVSEQFTATFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
::::.:: ::.::.::: ::.:::::: ::::::::::::::::::::::::::::::::
NP_001 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
420 430
pF1KB7 EYQQYQDATAEGGGV
::::::::::. :
NP_001 EYQQYQDATADEQGEFEEEEGEDEA
430 440
>>NP_006077 (OMIM: 600638,602661,614039) tubulin beta-3 (450 aa)
initn: 2090 init1: 2090 opt: 2423 Z-score: 3044.3 bits: 572.5 E(85289): 7.8e-163
Smith-Waterman score: 2423; 82.7% identity (92.9% similar) in 434 aa overlap (1-433:1-434)
10 20 30 40 50 60
pF1KB7 MRELVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV
:::.: :.:::::::::::::::::::.:: .:.: ::: ::::::.:...:::. .::
NP_006 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 SRAVLVDLEPGTMDSVRSGPFGQVFRPDNFISRQCGAGNNWAKGRYTEGAELTESVMDVV
::.::::::::::::::: ::..::::::: : :::::::::.:::::::..::.:::
NP_006 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIWEEYPDRIINTLSILLLPKVSDTVV
::: :.::::::::::::::::::::::::::::. :::::::.::.:.. ::::::::
NP_006 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL
::::::::.:::.::.:::.::::::::::: ::::: :::::::::::::::::::: :
NP_006 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CFPDQLNADLRKLAMNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM
:: ::::::::::.:::::::::::::::::::.::::::::::: :::::::::::::
NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AARDPRHGRYLTAAAIFQGRMPMREVDEQMFNIQDKNSSYFADWFPNNVKTAVCDIPPWG
:: :::::::::.:..:.::: :.::::::. ::.::::::..:.:::::.::::::: :
NP_006 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 LKMSVTFTGNNTAVQEL-KRVSEQFTATFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
:::: :: ::.::.::: ::.:::::: ::::::::::::::::::::::::::::::::
NP_006 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
420 430
pF1KB7 EYQQYQDATAEGGGV
::::::::::: :
NP_006 EYQQYQDATAEEEGEMYEDDEEESEAQGPK
430 440 450
434 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:08:46 2016 done: Fri Nov 4 06:08:47 2016
Total Scan time: 7.410 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]