FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7234, 388 aa 1>>>pF1KB7234 388 - 388 aa - 388 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7524+/-0.000537; mu= -1.5621+/- 0.032 mean_var=279.5519+/-58.310, 0's: 0 Z-trim(113.5): 317 B-trim: 539 in 1/55 Lambda= 0.076708 statistics sampled from 22449 (22875) to 22449 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.268), width: 16 Scan time: 7.750 The best scores are: opt bits E(85289) NP_660339 (OMIM: 609744) cell adhesion molecule 4 ( 388) 2575 299.3 1e-80 XP_016881941 (OMIM: 609744) PREDICTED: cell adhesi ( 369) 2421 282.2 1.3e-75 XP_005258677 (OMIM: 609744) PREDICTED: cell adhesi ( 345) 2054 241.6 2.2e-63 NP_001091987 (OMIM: 605686) cell adhesion molecule ( 414) 1003 125.4 2.5e-28 NP_001161147 (OMIM: 609938) cell adhesion molecule ( 404) 876 111.3 4.2e-24 XP_006713145 (OMIM: 609938) PREDICTED: cell adhesi ( 395) 868 110.4 7.6e-24 XP_016861552 (OMIM: 609938) PREDICTED: cell adhesi ( 397) 868 110.4 7.7e-24 NP_055148 (OMIM: 605686) cell adhesion molecule 1 ( 442) 844 107.8 5.2e-23 NP_001287973 (OMIM: 605686) cell adhesion molecule ( 453) 844 107.8 5.3e-23 NP_001287972 (OMIM: 605686) cell adhesion molecule ( 471) 844 107.8 5.4e-23 XP_005271551 (OMIM: 605686) PREDICTED: cell adhesi ( 425) 841 107.4 6.4e-23 NP_001287974 (OMIM: 605686) cell adhesion molecule ( 443) 836 106.9 9.6e-23 XP_016872947 (OMIM: 605686) PREDICTED: cell adhesi ( 402) 822 105.3 2.6e-22 XP_016872946 (OMIM: 605686) PREDICTED: cell adhesi ( 477) 823 105.5 2.7e-22 NP_001120645 (OMIM: 609743) cell adhesion molecule ( 398) 804 103.3 1e-21 NP_067012 (OMIM: 609743) cell adhesion molecule 3 ( 432) 790 101.8 3.2e-21 XP_006713144 (OMIM: 609938) PREDICTED: cell adhesi ( 435) 717 93.7 8.7e-19 NP_001161146 (OMIM: 609938) cell adhesion molecule ( 435) 717 93.7 8.7e-19 NP_694854 (OMIM: 609938) cell adhesion molecule 2 ( 437) 717 93.7 8.8e-19 XP_016861551 (OMIM: 609938) PREDICTED: cell adhesi ( 449) 717 93.7 8.9e-19 XP_016872950 (OMIM: 605686) PREDICTED: cell adhesi ( 267) 650 86.1 1.1e-16 NP_001243433 (OMIM: 609938) cell adhesion molecule ( 287) 624 83.2 8.3e-16 NP_001243434 (OMIM: 609938) cell adhesion molecule ( 287) 624 83.2 8.3e-16 XP_016872949 (OMIM: 605686) PREDICTED: cell adhesi ( 295) 491 68.5 2.3e-11 XP_016872948 (OMIM: 605686) PREDICTED: cell adhesi ( 324) 491 68.6 2.4e-11 NP_115499 (OMIM: 607762) kin of IRRE-like protein ( 633) 377 56.3 2.4e-07 XP_016882837 (OMIM: 607762) PREDICTED: kin of IRRE ( 673) 377 56.3 2.5e-07 XP_011525665 (OMIM: 607762) PREDICTED: kin of IRRE ( 708) 377 56.3 2.6e-07 XP_011525664 (OMIM: 607762) PREDICTED: kin of IRRE ( 708) 377 56.3 2.6e-07 NP_954649 (OMIM: 607762) kin of IRRE-like protein ( 708) 377 56.3 2.6e-07 NP_060710 (OMIM: 607428) kin of IRRE-like protein ( 757) 368 55.4 5.4e-07 XP_005245362 (OMIM: 607428) PREDICTED: kin of IRRE ( 773) 368 55.4 5.4e-07 NP_001333439 (OMIM: 609743) cell adhesion molecule ( 352) 338 51.7 3.2e-06 NP_001155179 (OMIM: 607761,612581) kin of IRRE-lik ( 600) 342 52.4 3.4e-06 NP_954648 (OMIM: 607762) kin of IRRE-like protein ( 583) 341 52.3 3.6e-06 NP_001316459 (OMIM: 607762) kin of IRRE-like prote ( 658) 341 52.3 3.9e-06 XP_011525667 (OMIM: 607762) PREDICTED: kin of IRRE ( 658) 341 52.3 3.9e-06 XP_011541335 (OMIM: 607761,612581) PREDICTED: kin ( 766) 342 52.5 4e-06 NP_001288026 (OMIM: 607761,612581) kin of IRRE-lik ( 766) 342 52.5 4e-06 XP_011541334 (OMIM: 607761,612581) PREDICTED: kin ( 772) 342 52.5 4e-06 NP_115920 (OMIM: 607761,612581) kin of IRRE-like p ( 778) 342 52.5 4e-06 XP_016873909 (OMIM: 607761,612581) PREDICTED: kin ( 778) 342 52.5 4e-06 XP_011541333 (OMIM: 607761,612581) PREDICTED: kin ( 778) 342 52.5 4e-06 XP_011541332 (OMIM: 607761,612581) PREDICTED: kin ( 784) 342 52.5 4e-06 XP_016873908 (OMIM: 607761,612581) PREDICTED: kin ( 791) 342 52.5 4.1e-06 XP_011541329 (OMIM: 607761,612581) PREDICTED: kin ( 803) 342 52.5 4.1e-06 XP_016873907 (OMIM: 607761,612581) PREDICTED: kin ( 803) 342 52.5 4.1e-06 XP_011541330 (OMIM: 607761,612581) PREDICTED: kin ( 803) 342 52.5 4.1e-06 XP_011541328 (OMIM: 607761,612581) PREDICTED: kin ( 809) 342 52.5 4.1e-06 NP_002846 (OMIM: 225060,600644) nectin-1 isoform 1 ( 517) 300 47.7 7.7e-05 >>NP_660339 (OMIM: 609744) cell adhesion molecule 4 prec (388 aa) initn: 2575 init1: 2575 opt: 2575 Z-score: 1570.1 bits: 299.3 E(85289): 1e-80 Smith-Waterman score: 2575; 100.0% identity (100.0% similar) in 388 aa overlap (1-388:1-388) 10 20 30 40 50 60 pF1KB7 MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 RQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LVAPENPVVEVREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LVAPENPVVEVREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 ASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 RALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 RALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEA 310 320 330 340 350 360 370 380 pF1KB7 SGLDEQGEAREAFLNGSDGHKRKEEFFI :::::::::::::::::::::::::::: NP_660 SGLDEQGEAREAFLNGSDGHKRKEEFFI 370 380 >>XP_016881941 (OMIM: 609744) PREDICTED: cell adhesion m (369 aa) initn: 2421 init1: 2421 opt: 2421 Z-score: 1478.2 bits: 282.2 E(85289): 1.3e-75 Smith-Waterman score: 2421; 100.0% identity (100.0% similar) in 367 aa overlap (22-388:3-369) 10 20 30 40 50 60 pF1KB7 MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPA ::::::::::::::::::::::::::::::::::::::: XP_016 MTGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPA 10 20 30 40 70 80 90 100 110 120 pF1KB7 RQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTV 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB7 LVAPENPVVEVREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVAPENPVVEVREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSV 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB7 ASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDT 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB7 LVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB7 RALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEA 290 300 310 320 330 340 370 380 pF1KB7 SGLDEQGEAREAFLNGSDGHKRKEEFFI :::::::::::::::::::::::::::: XP_016 SGLDEQGEAREAFLNGSDGHKRKEEFFI 350 360 >>XP_005258677 (OMIM: 609744) PREDICTED: cell adhesion m (345 aa) initn: 2279 init1: 2054 opt: 2054 Z-score: 1259.1 bits: 241.6 E(85289): 2.2e-63 Smith-Waterman score: 2197; 88.9% identity (88.9% similar) in 388 aa overlap (1-388:1-345) 10 20 30 40 50 60 pF1KB7 MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 LVAPENPVVEVREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVAPENPVVEVREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 ASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 RALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEA ::::::::: :::::::: XP_005 RALYVLVVY-------------------------------------------GSYLTHEA 310 370 380 pF1KB7 SGLDEQGEAREAFLNGSDGHKRKEEFFI :::::::::::::::::::::::::::: XP_005 SGLDEQGEAREAFLNGSDGHKRKEEFFI 320 330 340 >>NP_001091987 (OMIM: 605686) cell adhesion molecule 1 i (414 aa) initn: 984 init1: 362 opt: 1003 Z-score: 629.5 bits: 125.4 E(85289): 2.5e-28 Smith-Waterman score: 1003; 40.8% identity (73.5% similar) in 392 aa overlap (6-388:25-414) 10 20 30 40 pF1KB7 MGRARRFQWPLLLLWAAAAGP-GAGQEVQTENVTVAEGGVA :.. :::. ::: : : ::.. :..::: :: :: NP_001 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 EITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEG :.:.... : :.. . :: :::..: : ::: :::: .:: .... :... . ::: NP_001 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 70 80 90 100 110 120 110 120 130 140 150 pF1KB7 GYFCQLYTEDTHHQIATLTVLVAPENPVVEV-REQAVEGGEVELSCLVPRSRPAATLRWY :::::::. ... .:.:::: :.: .... .. :::: :.:..: . :.::.:.::. NP_001 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 RDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLD . :::: : .: . ...:.: . ..: ..::: .::.... :. .:. ::: :. NP_001 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV-TGNL-QTQRYLE 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 VQYSPTARIHAS---QAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETL :::.: ..:. . :...::::.: ::: . :.:.: .. : : .. .:..: : .: NP_001 VQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNL 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 TLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVEAQT-SVPYAIVGGILALLVF . .: ..::::: ::::: :.:.. :.: ::: : :.. .: .:..::..:..:: NP_001 FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVF 300 310 320 330 340 350 340 350 360 370 380 pF1KB7 LIICVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLN---GSDGHKRKEEFFI ..:.:. . .:.::.:.::::.: :. ..: :..: :... ..:.:.:: NP_001 AMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 360 370 380 390 400 410 >>NP_001161147 (OMIM: 609938) cell adhesion molecule 2 i (404 aa) initn: 668 init1: 291 opt: 876 Z-score: 553.7 bits: 111.3 E(85289): 4.2e-24 Smith-Waterman score: 876; 39.5% identity (70.8% similar) in 390 aa overlap (12-388:17-404) 10 20 30 40 50 pF1KB7 MGRARRFQWPLLLLWAAAAG---PGA-GQEVQTENVTVAEGGVAEITCRLHQYDG ::: :::. :. :: :.::::.:::.: .:::. : :. NP_001 MIWKRSAVLRFYSVCGLLLQAAASKNKVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 SIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDT . . .:::.:::.:. .::.:.:..: . : ... : .::. : ::: : :.:.: . NP_001 TSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 HHQIATLTVLVAPENPVVE-VREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSS . . : :::: .::.: . ..:: ..:.: . :.::: .::... ::.: :. NP_001 KTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKY 130 140 150 160 170 180 180 190 200 210 220 pF1KB7 SQE---NGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTAR .: : :...:.::. :::::.::: .::......: . . : ::...:.:... NP_001 LKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQ-VLEIHYTPSVK 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 IHASQAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPE--RAEAVGETLTLPGLVSAD : : .::. :.::: :.: :. . :.. . ::. : . :. :.. : ..: NP_001 IIPSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTD 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 NGTYTCEASNKHGHARALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMV :::: :::.: :.. : :::.:.::.:.. .:.. .:..:::.:..::. .: . . NP_001 NGTYRCEATNTIGQSSAEYVLIVHDPNALA-GQNGPDHALIGGIVAVVVFVTLCSIFLLG 300 310 320 330 340 350 350 360 370 380 pF1KB7 WCSVRQKGSYLTHEASGLDEQGEAREAFLN--GSD-GHKRKEEFFI .:.::.:::.::.: .. .: :..: ::. . ..:.:.:: NP_001 RYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 360 370 380 390 400 >>XP_006713145 (OMIM: 609938) PREDICTED: cell adhesion m (395 aa) initn: 668 init1: 291 opt: 868 Z-score: 549.0 bits: 110.4 E(85289): 7.6e-24 Smith-Waterman score: 868; 39.3% identity (71.4% similar) in 374 aa overlap (24-388:24-395) 10 20 30 40 50 60 pF1KB7 MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPA :: :.::::.:::.: .:::. : :.. . .::: XP_006 MIWKRSAVLRFYSVCGLLLQGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 RQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTV .:::.:. .::.:.:..: . : ... : .::. : ::: : :.:.: .. . : ::: XP_006 QQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTV 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 LVAPENPVVE-VREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQE---NGK : .::.: . ..:: ..:.: . :.::: .::... ::.: :. .: : : XP_006 LGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 VWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVR ...:.::. :::::.::: .::......: . . : ::...:.:...: : . XP_006 TFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQ-VLEIHYTPSVKIIPSTPFPQ 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 EGDTLVLTCAVTGNPRPNQIRWNRGNESLPE--RAEAVGETLTLPGLVSADNGTYTCEAS ::. :.::: :.: :. . :.. . ::. : . :. :.. : ..::::: :::. XP_006 EGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEAT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 NKHGHARALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGS : :.. : :::.:.::.:.. .:.. .:..:::.:..::. .: . . .:.::. XP_006 NTIGQSSAEYVLIVHDPNALA-GQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARHKGT 300 310 320 330 340 350 360 370 380 pF1KB7 YLTHEASGLDEQGEAREAFLN--GSD-GHKRKEEFFI :::.::.: .. .: :..: ::. . ..:.:.:: XP_006 YLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 360 370 380 390 >>XP_016861552 (OMIM: 609938) PREDICTED: cell adhesion m (397 aa) initn: 668 init1: 291 opt: 868 Z-score: 549.0 bits: 110.4 E(85289): 7.7e-24 Smith-Waterman score: 868; 39.3% identity (71.4% similar) in 374 aa overlap (24-388:26-397) 10 20 30 40 50 pF1KB7 MGRARRFQWPLLLLWAAAAGPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQN :: :.::::.:::.: .:::. : :.. . .: XP_016 MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 PARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATL ::.:::.:. .::.:.:..: . : ... : .::. : ::: : :.:.: .. . : : XP_016 PAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 TVLVAPENPVVE-VREQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQE---N ::: .::.: . ..:: ..:.: . :.::: .::... ::.: :. .: : XP_016 TVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDAN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 GKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAV :...:.::. :::::.::: .::......: . . : ::...:.:...: : XP_016 RKTFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQ-VLEIHYTPSVKIIPSTPF 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 VREGDTLVLTCAVTGNPRPNQIRWNRGNESLPE--RAEAVGETLTLPGLVSADNGTYTCE .::. :.::: :.: :. . :.. . ::. : . :. :.. : ..::::: :: XP_016 PQEGQPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 ASNKHGHARALYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQK :.: :.. : :::.:.::.:.. .:.. .:..:::.:..::. .: . . .:.: XP_016 ATNTIGQSSAEYVLIVHDPNALA-GQNGPDHALIGGIVAVVVFVTLCSIFLLGRYLARHK 300 310 320 330 340 350 360 370 380 pF1KB7 GSYLTHEASGLDEQGEAREAFLN--GSD-GHKRKEEFFI :.:::.::.: .. .: :..: ::. . ..:.:.:: XP_016 GTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 360 370 380 390 >>NP_055148 (OMIM: 605686) cell adhesion molecule 1 isof (442 aa) initn: 839 init1: 362 opt: 844 Z-score: 534.1 bits: 107.8 E(85289): 5.2e-23 Smith-Waterman score: 957; 38.2% identity (68.6% similar) in 414 aa overlap (6-385:25-436) 10 20 30 40 pF1KB7 MGRARRFQWPLLLLWAAAAGP-GAGQEVQTENVTVAEGGVA :.. :::. ::: : : ::.. :..::: :: :: NP_055 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 EITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEG :.:.... : :.. . :: :::..: : ::: :::: .:: .... :... . ::: NP_055 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 70 80 90 100 110 120 110 120 130 140 150 pF1KB7 GYFCQLYTEDTHHQIATLTVLVAPENPVVEV-REQAVEGGEVELSCLVPRSRPAATLRWY :::::::. ... .:.:::: :.: .... .. :::: :.:..: . :.::.:.::. NP_055 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 RDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLD . :::: : .: . ...:.: . ..: ..::: .::.... :. .:. ::: :. NP_055 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV-TGNL-QTQRYLE 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 VQYSPTARIHAS---QAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETL :::.: ..:. . :...::::.: ::: . :.:.: .. : : .. .:..: : .: NP_055 VQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNL 240 250 260 270 280 290 280 290 300 310 320 pF1KB7 TLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVEAQTS---------------- . .: ..::::: ::::: :.:.. :.: :::: ... :. NP_055 FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTII 300 310 320 330 340 350 330 340 350 360 pF1KB7 -------------VPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEASGLDEQG : .:..::..:..:: ..:.:. . .:.::.:.::::.: :. . NP_055 TDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAA 360 370 380 390 400 410 370 380 pF1KB7 EAREAFLNGSDGHKRKEEFFI .: :..:. :.. .:: NP_055 DADTAIINAEGGQNNSEEKKEYFI 420 430 440 >>NP_001287973 (OMIM: 605686) cell adhesion molecule 1 i (453 aa) initn: 999 init1: 362 opt: 844 Z-score: 534.0 bits: 107.8 E(85289): 5.3e-23 Smith-Waterman score: 917; 37.3% identity (66.7% similar) in 415 aa overlap (6-375:25-437) 10 20 30 40 pF1KB7 MGRARRFQWPLLLLWAAAAGP-GAGQEVQTENVTVAEGGVA :.. :::. ::: : : ::.. :..::: :: :: NP_001 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 EITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEG :.:.... : :.. . :: :::..: : ::: :::: .:: .... :... . ::: NP_001 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 70 80 90 100 110 120 110 120 130 140 150 pF1KB7 GYFCQLYTEDTHHQIATLTVLVAPENPVVEV-REQAVEGGEVELSCLVPRSRPAATLRWY :::::::. ... .:.:::: :.: .... .. :::: :.:..: . :.::.:.::. NP_001 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 RDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLD . :::: : .: . ...:.: . ..: ..::: .::.... :. .:. ::: :. NP_001 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV-TGNL-QTQRYLE 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 VQYSPTARIHAS---QAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETL :::.: ..:. . :...::::.: ::: . :.:.: .. : : .. .:..: : .: NP_001 VQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNL 240 250 260 270 280 290 280 290 300 310 320 pF1KB7 TLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVEAQTS---------------- . .: ..::::: ::::: :.:.. :.: :::: ... :. NP_001 FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTII 300 310 320 330 340 350 330 340 350 pF1KB7 ------------------------VPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYL : .:..::..:..:: ..:.:. . .:.::.:. NP_001 TDTTATTEPAVHDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYF 360 370 380 390 400 410 360 370 380 pF1KB7 THEASGLDEQGEAREAFLNGSDGHKRKEEFFI ::::.: :. ..: :..: NP_001 THEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 420 430 440 450 >>NP_001287972 (OMIM: 605686) cell adhesion molecule 1 i (471 aa) initn: 999 init1: 362 opt: 844 Z-score: 533.8 bits: 107.8 E(85289): 5.4e-23 Smith-Waterman score: 848; 35.9% identity (63.6% similar) in 418 aa overlap (6-360:25-440) 10 20 30 40 pF1KB7 MGRARRFQWPLLLLWAAAAGP-GAGQEVQTENVTVAEGGVA :.. :::. ::: : : ::.. :..::: :: :: NP_001 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB7 EITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSDARLEDEG :.:.... : :.. . :: :::..: : ::: :::: .:: .... :... . ::: NP_001 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 70 80 90 100 110 120 110 120 130 140 150 pF1KB7 GYFCQLYTEDTHHQIATLTVLVAPENPVVEV-REQAVEGGEVELSCLVPRSRPAATLRWY :::::::. ... .:.:::: :.: .... .. :::: :.:..: . :.::.:.::. NP_001 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB7 RDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLD . :::: : .: . ...:.: . ..: ..::: .::.... :. .:. ::: :. NP_001 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV-TGNL-QTQRYLE 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 VQYSPTARIHAS---QAVVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETL :::.: ..:. . :...::::.: ::: . :.:.: .. : : .. .:..: : .: NP_001 VQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNL 240 250 260 270 280 290 280 290 300 310 320 pF1KB7 TLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVEAQTS---------------- . .: ..::::: ::::: :.:.. :.: :::: ... :. NP_001 FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTII 300 310 320 330 340 350 330 pF1KB7 ------------------------------------------VPYAIVGGILALLVFLII : .:..::..:..:: .. NP_001 TDTTATTEPAVHGLTQLPNSAEELDSEDLSDSRAGEEGSIRAVDHAVIGGVVAVVVFAML 360 370 380 390 400 410 340 350 360 370 380 pF1KB7 CVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLNGSDGHKRKEEFFI :.:. . .:.::.:.:::: NP_001 CLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 420 430 440 450 460 470 388 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:45:27 2016 done: Sat Nov 5 09:45:28 2016 Total Scan time: 7.750 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]