FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7243, 458 aa 1>>>pF1KB7243 458 - 458 aa - 458 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4016+/-0.000373; mu= 17.3181+/- 0.023 mean_var=67.8470+/-13.776, 0's: 0 Z-trim(113.3): 87 B-trim: 0 in 0/54 Lambda= 0.155707 statistics sampled from 22435 (22523) to 22435 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.264), width: 16 Scan time: 9.680 The best scores are: opt bits E(85289) NP_940987 (OMIM: 616748) ectonucleoside triphospha ( 458) 3071 699.0 6.9e-201 XP_011516968 (OMIM: 616748) PREDICTED: ectonucleos ( 566) 3071 699.0 8.3e-201 NP_001028285 (OMIM: 616748) ectonucleoside triphos ( 495) 2329 532.3 1.1e-150 XP_011516967 (OMIM: 616748) PREDICTED: ectonucleos ( 603) 2329 532.4 1.3e-150 XP_011516970 (OMIM: 616748) PREDICTED: ectonucleos ( 368) 1531 353.0 8e-97 NP_982293 (OMIM: 602012) ectonucleoside triphospha ( 495) 1078 251.3 4.4e-66 NP_001237 (OMIM: 602012) ectonucleoside triphospha ( 472) 1069 249.3 1.7e-65 NP_001157651 (OMIM: 601752,615683) ectonucleoside ( 469) 1020 238.2 3.5e-62 XP_016872447 (OMIM: 601752,615683) PREDICTED: ecto ( 470) 999 233.5 9.2e-61 NP_001307845 (OMIM: 601752,615683) ectonucleoside ( 482) 999 233.5 9.4e-61 NP_001767 (OMIM: 601752,615683) ectonucleoside tri ( 510) 999 233.5 9.9e-61 XP_011538673 (OMIM: 601752,615683) PREDICTED: ecto ( 517) 999 233.5 1e-60 NP_001091645 (OMIM: 601752,615683) ectonucleoside ( 517) 999 233.5 1e-60 NP_001157650 (OMIM: 601752,615683) ectonucleoside ( 522) 999 233.6 1e-60 XP_011538678 (OMIM: 601752,615683) PREDICTED: ecto ( 430) 954 223.4 9.5e-58 XP_011538676 (OMIM: 601752,615683) PREDICTED: ecto ( 469) 954 223.4 1e-57 XP_011538675 (OMIM: 601752,615683) PREDICTED: ecto ( 481) 954 223.4 1e-57 XP_011538674 (OMIM: 601752,615683) PREDICTED: ecto ( 489) 954 223.4 1.1e-57 XP_011538672 (OMIM: 601752,615683) PREDICTED: ecto ( 529) 954 223.4 1.1e-57 NP_001278890 (OMIM: 603161) ectonucleoside triphos ( 452) 935 219.1 1.9e-56 NP_001239 (OMIM: 603161) ectonucleoside triphospha ( 529) 935 219.2 2.2e-56 NP_001278889 (OMIM: 603161) ectonucleoside triphos ( 529) 935 219.2 2.2e-56 XP_016872453 (OMIM: 601752,615683) PREDICTED: ecto ( 276) 775 183.1 8.3e-46 XP_016872452 (OMIM: 601752,615683) PREDICTED: ecto ( 288) 775 183.1 8.6e-46 XP_016872451 (OMIM: 601752,615683) PREDICTED: ecto ( 295) 730 173.0 9.7e-43 XP_016872449 (OMIM: 601752,615683) PREDICTED: ecto ( 362) 719 170.6 6.4e-42 NP_001299583 (OMIM: 601752,615683) ectonucleoside ( 402) 719 170.6 7e-42 XP_011538679 (OMIM: 601752,615683) PREDICTED: ecto ( 402) 719 170.6 7e-42 NP_001157653 (OMIM: 601752,615683) ectonucleoside ( 402) 719 170.6 7e-42 XP_011532568 (OMIM: 603161) PREDICTED: ectonucleos ( 283) 685 162.9 1e-39 XP_016872450 (OMIM: 601752,615683) PREDICTED: ecto ( 332) 601 144.0 5.7e-34 NP_001157655 (OMIM: 601752,615683) ectonucleoside ( 372) 601 144.1 6.2e-34 NP_001157654 (OMIM: 601752,615683) ectonucleoside ( 372) 601 144.1 6.2e-34 XP_016872448 (OMIM: 601752,615683) PREDICTED: ecto ( 372) 601 144.1 6.2e-34 NP_001308917 (OMIM: 603162) ectonucleoside triphos ( 428) 323 81.6 4.4e-15 NP_001308916 (OMIM: 603162) ectonucleoside triphos ( 428) 323 81.6 4.4e-15 NP_001240 (OMIM: 603162) ectonucleoside triphospha ( 428) 323 81.6 4.4e-15 NP_001308914 (OMIM: 603162) ectonucleoside triphos ( 428) 323 81.6 4.4e-15 NP_001308915 (OMIM: 603162) ectonucleoside triphos ( 428) 323 81.6 4.4e-15 XP_016877302 (OMIM: 603162) PREDICTED: ectonucleos ( 428) 323 81.6 4.4e-15 XP_005268281 (OMIM: 603162) PREDICTED: ectonucleos ( 428) 323 81.6 4.4e-15 XP_016877306 (OMIM: 603162) PREDICTED: ectonucleos ( 360) 296 75.5 2.6e-13 XP_006720389 (OMIM: 603162) PREDICTED: ectonucleos ( 381) 296 75.6 2.7e-13 XP_016877305 (OMIM: 603162) PREDICTED: ectonucleos ( 381) 296 75.6 2.7e-13 NP_001308913 (OMIM: 603162) ectonucleoside triphos ( 405) 296 75.6 2.8e-13 XP_006720388 (OMIM: 603162) PREDICTED: ectonucleos ( 407) 296 75.6 2.8e-13 XP_016877303 (OMIM: 603162) PREDICTED: ectonucleos ( 407) 296 75.6 2.8e-13 NP_001317118 (OMIM: 603162) ectonucleoside triphos ( 407) 296 75.6 2.8e-13 XP_011517514 (OMIM: 602012) PREDICTED: ectonucleos ( 392) 283 72.6 2.1e-12 NP_065087 (OMIM: 616753) ectonucleoside triphospha ( 604) 277 71.4 7.6e-12 >>NP_940987 (OMIM: 616748) ectonucleoside triphosphate d (458 aa) initn: 3071 init1: 3071 opt: 3071 Z-score: 3727.5 bits: 699.0 E(85289): 6.9e-201 Smith-Waterman score: 3071; 100.0% identity (100.0% similar) in 458 aa overlap (1-458:1-458) 10 20 30 40 50 60 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYVEASYPGQDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYVEASYPGQDR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 WLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_940 WLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAP 370 380 390 400 410 420 430 440 450 pF1KB7 AQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD :::::::::::::::::::::::::::::::::::::: NP_940 AQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD 430 440 450 >>XP_011516968 (OMIM: 616748) PREDICTED: ectonucleoside (566 aa) initn: 3071 init1: 3071 opt: 3071 Z-score: 3726.1 bits: 699.0 E(85289): 8.3e-201 Smith-Waterman score: 3071; 100.0% identity (100.0% similar) in 458 aa overlap (1-458:109-566) 10 20 30 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLV :::::::::::::::::::::::::::::: XP_011 GQPAQNCVRTPQRVPLSTCPGAPGTSTTCTMGLSRKEQVFLALLGASGVSGLTALILLLV 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB7 EATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTS 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB7 NAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVL 200 210 220 230 240 250 160 170 180 190 200 210 pF1KB7 GRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGAS 260 270 280 290 300 310 220 230 240 250 260 270 pF1KB7 TQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLR 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB7 HPCYLSGYQTTLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPCYLSGYQTTLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQ 380 390 400 410 420 430 340 350 360 370 380 390 pF1KB7 GQEDCAFDGVYQPPLRGQFYVEASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQEDCAFDGVYQPPLRGQFYVEASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSL 440 450 460 470 480 490 400 410 420 430 440 450 pF1KB7 EFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAAL 500 510 520 530 540 550 pF1KB7 VQLFWLQD :::::::: XP_011 VQLFWLQD 560 >>NP_001028285 (OMIM: 616748) ectonucleoside triphosphat (495 aa) initn: 3060 init1: 2329 opt: 2329 Z-score: 2826.2 bits: 532.3 E(85289): 1.1e-150 Smith-Waterman score: 2944; 92.4% identity (92.4% similar) in 490 aa overlap (1-453:1-490) 10 20 30 40 50 60 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS 250 260 270 280 290 300 310 320 330 340 350 pF1KB7 LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFY---------- :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFH 310 320 330 340 350 360 360 370 380 pF1KB7 ---------------------------VEASYPGQDRWLRDYCASGLYILTLLHEGYGFS ::::::::::::::::::::::::::::::::: NP_001 FLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFS 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB7 EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV 430 440 450 460 470 480 450 pF1KB7 AVVGAALVQLFWLQD :::::::::: NP_001 AVVGAALVQLFWLQD 490 >>XP_011516967 (OMIM: 616748) PREDICTED: ectonucleoside (603 aa) initn: 3060 init1: 2329 opt: 2329 Z-score: 2824.9 bits: 532.4 E(85289): 1.3e-150 Smith-Waterman score: 2944; 92.4% identity (92.4% similar) in 490 aa overlap (1-453:109-598) 10 20 30 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLV :::::::::::::::::::::::::::::: XP_011 GQPAQNCVRTPQRVPLSTCPGAPGTSTTCTMGLSRKEQVFLALLGASGVSGLTALILLLV 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB7 EATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTS 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB7 NAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVL 200 210 220 230 240 250 160 170 180 190 200 210 pF1KB7 GRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGAS 260 270 280 290 300 310 220 230 240 250 260 270 pF1KB7 TQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLR 320 330 340 350 360 370 280 290 300 310 320 330 pF1KB7 HPCYLSGYQTTLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPCYLSGYQTTLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQ 380 390 400 410 420 430 340 350 pF1KB7 GQEDCAFDGVYQPPLRGQFY-------------------------------------VEA :::::::::::::::::::: ::: XP_011 GQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPLSTVNATIWEFCQRPWKLVEA 440 450 460 470 480 490 360 370 380 390 400 410 pF1KB7 SYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTG 500 510 520 530 540 550 420 430 440 450 pF1KB7 MIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD :::::::::::::::::::::::::::::::::::::::: XP_011 MIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD 560 570 580 590 600 >>XP_011516970 (OMIM: 616748) PREDICTED: ectonucleoside (368 aa) initn: 2262 init1: 1531 opt: 1531 Z-score: 1859.3 bits: 353.0 E(85289): 8e-97 Smith-Waterman score: 2146; 89.8% identity (89.8% similar) in 363 aa overlap (128-453:1-363) 100 110 120 130 140 150 pF1KB7 SLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDF :::::::::::::::::::::::::::::: XP_011 MRLLSRKNSSQARDIFAAVTQVLGRSPVDF 10 20 30 160 170 180 190 200 210 pF1KB7 WGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVP 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB7 GGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSG 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB7 YQTTLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQTTLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAF 160 170 180 190 200 210 340 350 360 pF1KB7 DGVYQPPLRGQFY-------------------------------------VEASYPGQDR ::::::::::::: :::::::::: XP_011 DGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDR 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB7 WLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAP 280 290 300 310 320 330 430 440 450 pF1KB7 AQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD ::::::::::::::::::::::::::::::::: XP_011 AQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD 340 350 360 >>NP_982293 (OMIM: 602012) ectonucleoside triphosphate d (495 aa) initn: 1076 init1: 614 opt: 1078 Z-score: 1307.4 bits: 251.3 E(85289): 4.4e-66 Smith-Waterman score: 1252; 41.4% identity (70.0% similar) in 483 aa overlap (13-453:13-486) 10 20 30 40 50 60 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ ::.:.:..:: .:: : . .: : .:.:::.::::::::.:.:. NP_982 MAGKVRSLLPPLLLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYK 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT : :.::: ::.:.: .:.: : :::::..: . :..:: ::::.:: .:. .: :: NP_982 WPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL .::::::::::. : . ... :::..: . : :: ::..:.:: ::.:::.:.:: : NP_982 YLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY ...::...:.:..: . : ::.:.::::::::: .: :........:::. : :: NP_982 ENFIKYGWVGRWFRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVY 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS :::.::.::::.:.:::.. .:.. :::. :..: . :: .:.:::. : : . NP_982 THSFLCYGRDQVLQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQN 240 250 260 270 280 290 310 320 330 340 350 pF1KB7 LPQN--LTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFY-------- . .. ... :...: : . . ::.:::: .. :.:.::.:::. :.: NP_982 FNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYT 300 310 320 330 340 350 360 370 pF1KB7 --------------------------------VEASYPGQDRWLRDYCASGLYILTLLHE ..: ::: : ::::..... :: . NP_982 VDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSR 360 370 380 390 400 410 380 390 400 410 420 430 pF1KB7 GYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFM ::::.:... .. :.:.:. . .::.::::::::..:::: :. .. ... ::. .... NP_982 GYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLF 420 430 440 450 460 470 440 450 pF1KB7 VLALVAVVGAALVQLFWLQD . ::.:.. : :. NP_982 ASALLAALVLLLRQVHSAKLPSTI 480 490 >>NP_001237 (OMIM: 602012) ectonucleoside triphosphate d (472 aa) initn: 1246 init1: 614 opt: 1069 Z-score: 1296.8 bits: 249.3 E(85289): 1.7e-65 Smith-Waterman score: 1228; 42.4% identity (72.3% similar) in 462 aa overlap (13-453:13-463) 10 20 30 40 50 60 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ ::.:.:..:: .:: : . .: : .:.:::.::::::::.:.:. NP_001 MAGKVRSLLPPLLLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYK 10 20 30 40 50 70 80 90 100 110 120 pF1KB7 WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT : :.::: ::.:.: .:.: : :::::..: . :..:: ::::.:: .:. .: :: NP_001 WPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB7 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL .::::::::::. : . ... :::..: . : :: ::..:.:: ::.:::.:.:: : NP_001 YLGATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB7 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY ...::...:.:..: . : ::.:.::::::::: .: :........:::. : :: NP_001 ENFIKYGWVGRWFRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVY 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB7 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS :::.::.::::.:.:::.. .:.. :::. :..: . :: .:.:::. : : . NP_001 THSFLCYGRDQVLQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQN 240 250 260 270 280 290 310 320 330 340 350 pF1KB7 LPQN--LTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYVEASYPGQ . .. ... :...: : . . ::.:::: .. :.:.::.:::. :.: . ... NP_001 FNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYT 300 310 320 330 340 350 360 370 380 390 pF1KB7 DRWLRDYCASGLYILTL-------------------LHEGYGFSEETWPSLEFRKQAGGV .:: . :: . :: : .::::.:... .. :.:.:. . NP_001 VDFLR--TSMGLPVATLQQLEAAAVNVCNQTWAQQLLSRGYGFDERAFGGVIFQKKAADT 360 370 380 390 400 400 410 420 430 440 450 pF1KB7 DIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD .::.::::::::..:::: :. .. ... ::. ..... ::.:.. : :. NP_001 AVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLLRQVHSAKLP 410 420 430 440 450 460 NP_001 STI 470 >>NP_001157651 (OMIM: 601752,615683) ectonucleoside trip (469 aa) initn: 919 init1: 556 opt: 1020 Z-score: 1237.3 bits: 238.2 E(85289): 3.5e-62 Smith-Waterman score: 1020; 39.3% identity (67.2% similar) in 460 aa overlap (11-455:18-465) 10 20 30 40 50 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSH ::.:: :.. .. ::. . . ...: : ..:.:::.:::::: NP_001 MEDTKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKAL-PENVKYGIVLDAGSSH 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 TSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEA :::..:.: :.::: :::: :. :.:.:::::...... . : : :.:.: .::.. NP_001 TSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 QHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGW ::..::..:::::::::: .. : .. .: . :. : :: ::....:: :::.:: NP_001 QHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGW 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 ITVNYGLGTLVKYSFTGEW--IQPPE---EMLVGALDMGGASTQITFVPGGPILDKSTQA ::.:: :: :.: .: : : : . ::::.::::::.:::: . ... .: NP_001 ITINYLLG---KFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 -DFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPL .:::::.::.:::::.::.:.:: : . :. .:. . . : . .:. : : . NP_001 LQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQQFEIQGIGN--YQQCHQSILEL--F 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 YESPCVH---ATPPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPP : : . : . :: ..: . . . ...:..: . ... . . . . NP_001 NTSYCPYSQCAFNGIFLPP---LQGDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFC 300 310 320 330 340 350 360 370 380 390 400 pF1KB7 LRGQFYVEASYPG-QDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGW . ...:: : ....: .:: :: :::.:: .:: :. ..: ..: . : : :: NP_001 AQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGW 350 360 370 380 390 400 410 420 430 440 450 pF1KB7 TLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVF--MVLALVAVVGAALVQ---LFWLQD :::::::::.::::. : . :....: .:. .:: ::..: . . :: NP_001 TLGYMLNLTNMIPAEQPLS-TPLSHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDM 410 420 430 440 450 460 NP_001 V >>XP_016872447 (OMIM: 601752,615683) PREDICTED: ectonucl (470 aa) initn: 1011 init1: 524 opt: 999 Z-score: 1211.8 bits: 233.5 E(85289): 9.2e-61 Smith-Waterman score: 1048; 40.9% identity (66.8% similar) in 428 aa overlap (11-392:18-439) 10 20 30 40 50 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSH ::.:: :.. .. ::. . . ...: : ..:.:::.:::::: XP_016 MEDTKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKAL-PENVKYGIVLDAGSSH 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 TSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEA :::..:.: :.::: :::: :. :.:.:::::...... . : : :.:.: .::.. XP_016 TSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 QHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGW ::..::..:::::::::: .. : .. .: . :. : :: ::....:: :::.:: XP_016 QHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGW 120 130 140 150 160 170 180 190 200 210 220 pF1KB7 ITVNYGLGTLVKYSFTGEW--IQPPE---EMLVGALDMGGASTQITFVPGGPILDKSTQA ::.:: :: :.: .: : : : . ::::.::::::.:::: . ... .: XP_016 ITINYLLG---KFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB7 -DFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPL .:::::.::.:::::.::.:.:: : . :. .: .:: ::. ::. .. .. : XP_016 LQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDL 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 YESPCVHATPPLSLP-QNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLR :..::.. ..:: :.. ..: :: : ..: :::: : : .. :::.:.. :::. XP_016 YKTPCTKRFE-MTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQ-CAFNGIFLPPLQ 300 310 320 330 340 350 350 360 pF1KB7 GQF------Y--------------------------------VEASYPG-QDRWLRDYCA :.: : ...:: : ....: .:: XP_016 GDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCF 360 370 380 390 400 410 370 380 390 400 410 420 pF1KB7 SGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAES :: :::.:: .:: :. ..: ..: XP_016 SGTYILSLLLQGYHFTADSWEHIHFIGKSTEPSSWSTHEDGSLHGEYRMNPLCLLQ 420 430 440 450 460 470 >>NP_001307845 (OMIM: 601752,615683) ectonucleoside trip (482 aa) initn: 1011 init1: 524 opt: 999 Z-score: 1211.7 bits: 233.5 E(85289): 9.4e-61 Smith-Waterman score: 1048; 40.9% identity (66.8% similar) in 428 aa overlap (11-392:30-451) 10 20 30 40 pF1KB7 MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDI ::.:: :.. .. ::. . . ...: : .. NP_001 MGREELFLTFSFSSGFQESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKAL-PENV 10 20 30 40 50 50 60 70 80 90 100 pF1KB7 KFGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQG :.:::.:::::::::..:.: :.::: :::: :. :.:.:::::...... . : : NP_001 KYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTD 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB7 CLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAE :.:.: .::..::..::..:::::::::: .. : .. .: . :. : :: ::. NP_001 CMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGAR 120 130 140 150 160 170 170 180 190 200 210 pF1KB7 LLAGQAEGAFGWITVNYGLGTLVKYSFTGEW--IQPPE---EMLVGALDMGGASTQITFV ...:: :::.::::.:: :: :.: .: : : : . ::::.::::::.::: NP_001 IITGQEEGAYGWITINYLLG---KFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB7 PGGPILDKSTQA-DFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYL : . ... .: .:::::.::.:::::.::.:.:: : . :. .: .:: ::. NP_001 PQNQTIESPDNALQFRLYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFH 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB7 SGYQTTLALGPLYESPCVHATPPLSLP-QNLTVEGTGNPGACVSAIRELFNFSSCQGQED ::. .. .. ::..::.. ..:: :.. ..: :: : ..: :::: : : .. NP_001 PGYKKVVNVSDLYKTPCTKRFE-MTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQ- 300 310 320 330 340 350 340 350 pF1KB7 CAFDGVYQPPLRGQF------Y--------------------------------VEASYP :::.:.. :::.:.: : ...:: NP_001 CAFNGIFLPPLQGDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYA 360 370 380 390 400 410 360 370 380 390 400 410 pF1KB7 G-QDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMI : ....: .:: :: :::.:: .:: :. ..: ..: NP_001 GVKEKYLSEYCFSGTYILSLLLQGYHFTADSWEHIHFIGKSTEPSSWSTHEDGSLHGEYR 420 430 440 450 460 470 420 430 440 450 pF1KB7 PADAPAQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFWLQD NP_001 MNPLCLLQ 480 458 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:16:26 2016 done: Fri Nov 4 06:16:28 2016 Total Scan time: 9.680 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]