FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7244, 364 aa 1>>>pF1KB7244 364 - 364 aa - 364 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9581+/-0.000345; mu= 19.3980+/- 0.022 mean_var=92.6812+/-21.207, 0's: 0 Z-trim(116.7): 790 B-trim: 2518 in 2/49 Lambda= 0.133223 statistics sampled from 27250 (28147) to 27250 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.33), width: 16 Scan time: 8.460 The best scores are: opt bits E(85289) NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 2421 475.4 8.7e-134 NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 2421 475.4 8.7e-134 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 1322 264.3 3.7e-70 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 1322 264.3 3.7e-70 XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 1322 264.3 3.7e-70 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 1322 264.3 3.7e-70 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 1322 264.3 3.7e-70 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 1322 264.3 3.7e-70 NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 1322 264.3 3.7e-70 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 1289 257.9 2.7e-68 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 1146 230.4 5.3e-60 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 1087 219.1 1.4e-56 NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 821 167.9 3.1e-41 NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 817 167.2 5.8e-41 NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 817 167.2 5.8e-41 NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 817 167.2 5.9e-41 NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 817 167.2 5.9e-41 NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 817 167.2 5.9e-41 NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 817 167.2 5.9e-41 NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 817 167.2 6e-41 NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 817 167.2 6.1e-41 NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 817 167.2 6.1e-41 NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 817 167.2 6.3e-41 NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 817 167.3 6.8e-41 NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 817 167.3 6.8e-41 NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 796 163.1 9.2e-40 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 789 161.8 2.3e-39 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 789 161.8 2.3e-39 XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 789 161.8 2.3e-39 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 789 161.8 2.3e-39 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 789 161.8 2.4e-39 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 789 161.8 2.4e-39 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 789 161.8 2.4e-39 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 789 161.8 2.5e-39 NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 775 159.1 1.5e-38 XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 775 159.1 1.5e-38 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 746 153.5 7.3e-37 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 746 153.5 7.7e-37 NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 740 152.3 1.5e-36 NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 716 147.7 3.5e-35 NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 699 144.3 3.2e-34 NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 699 144.4 3.3e-34 NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 699 144.4 3.3e-34 XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 699 144.4 3.3e-34 NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 699 144.4 3.3e-34 NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 699 144.4 3.4e-34 XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 699 144.4 3.6e-34 XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 699 144.4 3.6e-34 XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 699 144.4 3.6e-34 XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 699 144.4 3.6e-34 >>NP_001044 (OMIM: 182455) somatostatin receptor type 5 (364 aa) initn: 2421 init1: 2421 opt: 2421 Z-score: 2522.9 bits: 475.4 E(85289): 8.7e-134 Smith-Waterman score: 2421; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364) 10 20 30 40 50 60 pF1KB7 MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ 310 320 330 340 350 360 pF1KB7 TSKL :::: NP_001 TSKL >>NP_001166031 (OMIM: 182455) somatostatin receptor type (364 aa) initn: 2421 init1: 2421 opt: 2421 Z-score: 2522.9 bits: 475.4 E(85289): 8.7e-134 Smith-Waterman score: 2421; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364) 10 20 30 40 50 60 pF1KB7 MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ 310 320 330 340 350 360 pF1KB7 TSKL :::: NP_001 TSKL >>XP_016884413 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1380.6 bits: 264.3 E(85289): 3.7e-70 Smith-Waterman score: 1322; 56.5% identity (79.6% similar) in 368 aa overlap (1-357:1-365) 10 20 30 40 50 pF1KB7 MEPLFPASTPSWNASSP-GAASGGGDNRTL----VGPAPSAGA-RAVLVPVLYLLVCAAG :. : :.:. . .: : .:.:. . :: .::.:.. : .::.:..::.::..: XP_016 MDMLHPSSVST--TSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRL : ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..::: XP_016 LLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPL ::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . ::. XP_016 VMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV .::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: XP_016 VVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGR 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 RV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFV :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::.: XP_016 RVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 VILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPP : : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: XP_016 VALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEED 300 310 320 330 340 350 350 360 pF1KB7 AHRAAANGLMQTSKL .... .: XP_016 GEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISY 360 370 380 390 400 410 >>XP_016884412 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1380.6 bits: 264.3 E(85289): 3.7e-70 Smith-Waterman score: 1322; 56.5% identity (79.6% similar) in 368 aa overlap (1-357:1-365) 10 20 30 40 50 pF1KB7 MEPLFPASTPSWNASSP-GAASGGGDNRTL----VGPAPSAGA-RAVLVPVLYLLVCAAG :. : :.:. . .: : .:.:. . :: .::.:.. : .::.:..::.::..: XP_016 MDMLHPSSVST--TSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRL : ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..::: XP_016 LLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPL ::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . ::. XP_016 VMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV .::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: XP_016 VVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGR 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 RV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFV :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::.: XP_016 RVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 VILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPP : : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: XP_016 VALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEED 300 310 320 330 340 350 350 360 pF1KB7 AHRAAANGLMQTSKL .... .: XP_016 GEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISY 360 370 380 390 400 410 >>XP_011528651 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1380.6 bits: 264.3 E(85289): 3.7e-70 Smith-Waterman score: 1322; 56.5% identity (79.6% similar) in 368 aa overlap (1-357:1-365) 10 20 30 40 50 pF1KB7 MEPLFPASTPSWNASSP-GAASGGGDNRTL----VGPAPSAGA-RAVLVPVLYLLVCAAG :. : :.:. . .: : .:.:. . :: .::.:.. : .::.:..::.::..: XP_011 MDMLHPSSVST--TSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRL : ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..::: XP_011 LLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPL ::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . ::. XP_011 VMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV .::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: XP_011 VVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGR 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 RV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFV :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::.: XP_011 RVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 VILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPP : : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: XP_011 VALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEED 300 310 320 330 340 350 350 360 pF1KB7 AHRAAANGLMQTSKL .... .: XP_011 GEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISY 360 370 380 390 400 410 >>NP_001265616 (OMIM: 182453) somatostatin receptor type (418 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1380.6 bits: 264.3 E(85289): 3.7e-70 Smith-Waterman score: 1322; 56.5% identity (79.6% similar) in 368 aa overlap (1-357:1-365) 10 20 30 40 50 pF1KB7 MEPLFPASTPSWNASSP-GAASGGGDNRTL----VGPAPSAGA-RAVLVPVLYLLVCAAG :. : :.:. . .: : .:.:. . :: .::.:.. : .::.:..::.::..: NP_001 MDMLHPSSVST--TSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRL : ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..::: NP_001 LLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPL ::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . ::. NP_001 VMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV .::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: NP_001 VVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGR 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 RV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFV :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::.: NP_001 RVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 VILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPP : : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: NP_001 VALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEED 300 310 320 330 340 350 350 360 pF1KB7 AHRAAANGLMQTSKL .... .: NP_001 GEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISY 360 370 380 390 400 410 >>XP_006724374 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1380.6 bits: 264.3 E(85289): 3.7e-70 Smith-Waterman score: 1322; 56.5% identity (79.6% similar) in 368 aa overlap (1-357:1-365) 10 20 30 40 50 pF1KB7 MEPLFPASTPSWNASSP-GAASGGGDNRTL----VGPAPSAGA-RAVLVPVLYLLVCAAG :. : :.:. . .: : .:.:. . :: .::.:.. : .::.:..::.::..: XP_006 MDMLHPSSVST--TSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRL : ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..::: XP_006 LLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPL ::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . ::. XP_006 VMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV .::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: XP_006 VVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGR 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 RV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFV :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::.: XP_006 RVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 VILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPP : : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: XP_006 VALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEED 300 310 320 330 340 350 350 360 pF1KB7 AHRAAANGLMQTSKL .... .: XP_006 GEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISY 360 370 380 390 400 410 >>XP_005261778 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1380.6 bits: 264.3 E(85289): 3.7e-70 Smith-Waterman score: 1322; 56.5% identity (79.6% similar) in 368 aa overlap (1-357:1-365) 10 20 30 40 50 pF1KB7 MEPLFPASTPSWNASSP-GAASGGGDNRTL----VGPAPSAGA-RAVLVPVLYLLVCAAG :. : :.:. . .: : .:.:. . :: .::.:.. : .::.:..::.::..: XP_005 MDMLHPSSVST--TSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRL : ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..::: XP_005 LLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPL ::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . ::. XP_005 VMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV .::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: XP_005 VVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGR 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 RV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFV :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::.: XP_005 RVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 VILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPP : : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: XP_005 VALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEED 300 310 320 330 340 350 350 360 pF1KB7 AHRAAANGLMQTSKL .... .: XP_005 GEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISY 360 370 380 390 400 410 >>NP_001042 (OMIM: 182453) somatostatin receptor type 3 (418 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1380.6 bits: 264.3 E(85289): 3.7e-70 Smith-Waterman score: 1322; 56.5% identity (79.6% similar) in 368 aa overlap (1-357:1-365) 10 20 30 40 50 pF1KB7 MEPLFPASTPSWNASSP-GAASGGGDNRTL----VGPAPSAGA-RAVLVPVLYLLVCAAG :. : :.:. . .: : .:.:. . :: .::.:.. : .::.:..::.::..: NP_001 MDMLHPSSVST--TSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVG 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 LGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRL : ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..::: NP_001 LLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 VMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPL ::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . ::. NP_001 VMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 LVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV .::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: NP_001 VVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGR 180 190 200 210 220 230 240 250 260 270 280 pF1KB7 RV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFV :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::.: NP_001 RVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 VILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPP : : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: NP_001 VALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEED 300 310 320 330 340 350 350 360 pF1KB7 AHRAAANGLMQTSKL .... .: NP_001 GEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISY 360 370 380 390 400 410 >>NP_001041 (OMIM: 182452) somatostatin receptor type 2 (369 aa) initn: 1253 init1: 654 opt: 1289 Z-score: 1347.0 bits: 257.9 E(85289): 2.7e-68 Smith-Waterman score: 1289; 55.7% identity (79.8% similar) in 336 aa overlap (32-362:36-368) 10 20 30 40 50 60 pF1KB7 EPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLV : . . :::. .:..:: :: ::::: NP_001 EPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLT-FIYFVVCIIGLCGNTLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 IYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGV :::.::.:::::.:::::::::.:: :.:::::::: : : :::: ..::.:::.::. NP_001 IYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 NQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV- :::::.:::::::.:::::::::..::.:::::.::. . :.: .:: . ::....: . NP_001 NQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLR 130 140 150 160 170 180 190 200 210 220 230 pF1KB7 --QEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGC : : ..:. .:: : : . ::::: .:::..:: .::::::.:..::...:.::: NP_001 SNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB7 VRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYAN .:. ::.:::::: .:: :: :::::. :. ....:. :: :.. :::.:.::: NP_001 SKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYAN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB7 SCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAAN :::::.::.::::::..:::.:::: : ::. :.. .. . :. : .. : ..:. : NP_001 SCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNE--TTETQRTLLN 310 320 330 340 350 360 360 pF1KB7 GLMQTSKL : .::: NP_001 GDLQTSI 364 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 09:46:03 2016 done: Sat Nov 5 09:46:04 2016 Total Scan time: 8.460 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]