FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7247, 596 aa 1>>>pF1KB7247 596 - 596 aa - 596 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3926+/-0.000403; mu= 18.9491+/- 0.025 mean_var=77.6791+/-16.190, 0's: 0 Z-trim(111.8): 24 B-trim: 0 in 0/54 Lambda= 0.145520 statistics sampled from 20442 (20462) to 20442 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.588), E-opt: 0.2 (0.24), width: 16 Scan time: 10.260 The best scores are: opt bits E(85289) NP_839947 (OMIM: 607828) otopetrin-3 isoform 1 [Ho ( 596) 3998 849.5 0 XP_011523046 (OMIM: 607828) PREDICTED: otopetrin-3 ( 567) 3773 802.2 0 NP_001258934 (OMIM: 607828) otopetrin-3 isoform 2 ( 578) 3771 801.8 0 XP_011523781 (OMIM: 607827) PREDICTED: otopetrin-2 ( 562) 556 126.8 1.9e-28 NP_835454 (OMIM: 607827) otopetrin-2 [Homo sapiens ( 562) 556 126.8 1.9e-28 NP_819056 (OMIM: 607806) otopetrin-1 [Homo sapiens ( 612) 297 72.5 4.7e-12 >>NP_839947 (OMIM: 607828) otopetrin-3 isoform 1 [Homo s (596 aa) initn: 3998 init1: 3998 opt: 3998 Z-score: 4536.7 bits: 849.5 E(85289): 0 Smith-Waterman score: 3998; 100.0% identity (100.0% similar) in 596 aa overlap (1-596:1-596) 10 20 30 40 50 60 pF1KB7 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 TRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 TRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 LLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 LLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 CLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 CLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 EASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 EASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 GAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 GAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWET 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB7 VPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 VPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNIT 490 500 510 520 530 540 550 560 570 580 590 pF1KB7 LWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_839 LWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA 550 560 570 580 590 >>XP_011523046 (OMIM: 607828) PREDICTED: otopetrin-3 iso (567 aa) initn: 3770 init1: 3770 opt: 3773 Z-score: 4281.7 bits: 802.2 E(85289): 0 Smith-Waterman score: 3773; 99.6% identity (99.8% similar) in 565 aa overlap (32-596:4-567) 10 20 30 40 50 60 pF1KB7 GRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAAT :: .:::::::::::::::::::::::::: XP_011 MPLPA-SEAQETEAAPEKENRVDVGAEERAAAT 10 20 30 70 80 90 100 110 120 pF1KB7 RPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 WILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFRV 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 GYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNLL 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB7 LWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEYC 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB7 LICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQIE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB7 ASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLMG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB7 AALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWETV 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB7 PEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITL 460 470 480 490 500 510 550 560 570 580 590 pF1KB7 WMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA 520 530 540 550 560 >>NP_001258934 (OMIM: 607828) otopetrin-3 isoform 2 [Hom (578 aa) initn: 3770 init1: 3770 opt: 3771 Z-score: 4279.3 bits: 801.8 E(85289): 0 Smith-Waterman score: 3771; 98.6% identity (98.8% similar) in 573 aa overlap (30-596:6-578) 10 20 30 40 50 pF1KB7 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPA------VGEAQETEAAPEKENRVDVGA :::: .::::::::::::::::::: NP_001 MPLPASAPAEATPMPSSEAQETEAAPEKENRVDVGA 10 20 30 60 70 80 90 100 110 pF1KB7 EERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKV 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB7 AVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTF 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB7 CLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLML 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB7 TLATNLLLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLATNLLLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLY 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB7 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB7 FVLFQIEASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVLFQIEASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSL 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB7 DVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHR 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB7 RPLWETVPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPLWETVPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFL 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB7 ILCNITLWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILCNITLWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYL 520 530 540 550 560 570 pF1KB7 GA :: NP_001 GA >>XP_011523781 (OMIM: 607827) PREDICTED: otopetrin-2 iso (562 aa) initn: 1445 init1: 556 opt: 556 Z-score: 631.7 bits: 126.8 E(85289): 1.9e-28 Smith-Waterman score: 1455; 43.0% identity (71.9% similar) in 540 aa overlap (84-594:25-560) 60 70 80 90 100 110 pF1KB7 AEERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNK .:.:.:.: :::.::..:. ..: . ::: XP_011 MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGGAFNK 10 20 30 40 50 120 130 140 150 160 170 pF1KB7 VAVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCT ::: ::. ::... .:. ::.:.:. :.: : :: :.: ::::.:.::.::::: :: XP_011 VAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGPIWLRGGLVLFGICT 60 70 80 90 100 110 180 190 200 210 220 230 pF1KB7 FCLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLM . ...:..:: : ..:.: . .. .:. ::. .::. :: ::::.:. ..: :::: XP_011 LIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQTYFLWVSAKDCVHVHLDLTWCGLM 120 130 140 150 160 170 240 250 260 270 280 pF1KB7 LTLATNLLLWVLAVTNDSMHRE--------IEAELGILMEKSTGNET--NTCLCLNATAC .::.::: .:. ::...:.:. .. .. .. . : . ..::: .:. : XP_011 FTLTTNLAIWMAAVVDESVHQSHSYSSSHSNASHARLISDQHADNPVGGDSCLCSTAV-C 180 190 200 210 220 230 290 300 310 320 330 340 pF1KB7 EAFRRGFLMLYPFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIF--GP . :..:...::::. :: :. ..:.:::::::: .: : . .: : : :: XP_011 QIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGP 240 250 260 270 280 290 350 360 370 380 390 400 pF1KB7 LLGLLVLLAGVCVFVLFQIEASGPAIAC-QYFTLYYAFYVAVLPTMSLACLAGTAIHGLE .::::....:. ::.......:: . : ...::.: .. : .:. :.:. :. .. XP_011 VLGLLLFVVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIYRFD 300 310 320 330 340 350 410 420 430 440 450 460 pF1KB7 ERELDTVKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQ .: .: :::::.:::.:::::::::..:.:.::::.:: :..:: : :...::.: : XP_011 RRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLAGLNLTHALLMIAQ 360 370 380 390 400 410 470 480 490 500 pF1KB7 HIAQNLFIIEGLHRRPLWETVPEGLAGKQE----------------AEPPRRGSLLELGQ : ::.::::.::: : :.. :. : :: : :. . XP_011 HTFQNMFIIESLHRGPPGAE-PHSTHPKEPCQDLTFTNLDALHTLSACPPNPG-LVSPSP 420 430 440 450 460 470 510 520 530 540 550 560 pF1KB7 GLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGY . :: ..: . : . .:.:. ::.:::::.:::. ::.::::: .:.: : .: ::::: XP_011 SDQREAVAIV-STPRSQWRRQCLKDISLFLLLCNVILWIMPAFGARPHFSNTVEVDFYGY 480 490 500 510 520 530 570 580 590 pF1KB7 QIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA ..: .:::. ::.:.:::::.:..:.:::. XP_011 SLWAVIVNICLPFGIFYRMHAVSSLLEVYVLS 540 550 560 >>NP_835454 (OMIM: 607827) otopetrin-2 [Homo sapiens] (562 aa) initn: 1445 init1: 556 opt: 556 Z-score: 631.7 bits: 126.8 E(85289): 1.9e-28 Smith-Waterman score: 1455; 43.0% identity (71.9% similar) in 540 aa overlap (84-594:25-560) 60 70 80 90 100 110 pF1KB7 AEERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNK .:.:.:.: :::.::..:. ..: . ::: NP_835 MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGGAFNK 10 20 30 40 50 120 130 140 150 160 170 pF1KB7 VAVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCT ::: ::. ::... .:. ::.:.:. :.: : :: :.: ::::.:.::.::::: :: NP_835 VAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGPIWLRGGLVLFGICT 60 70 80 90 100 110 180 190 200 210 220 230 pF1KB7 FCLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLM . ...:..:: : ..:.: . .. .:. ::. .::. :: ::::.:. ..: :::: NP_835 LIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQTYFLWVSAKDCVHVHLDLTWCGLM 120 130 140 150 160 170 240 250 260 270 280 pF1KB7 LTLATNLLLWVLAVTNDSMHRE--------IEAELGILMEKSTGNET--NTCLCLNATAC .::.::: .:. ::...:.:. .. .. .. . : . ..::: .:. : NP_835 FTLTTNLAIWMAAVVDESVHQSHSYSSSHSNASHARLISDQHADNPVGGDSCLCSTAV-C 180 190 200 210 220 230 290 300 310 320 330 340 pF1KB7 EAFRRGFLMLYPFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIF--GP . :..:...::::. :: :. ..:.:::::::: .: : . .: : : :: NP_835 QIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGP 240 250 260 270 280 290 350 360 370 380 390 400 pF1KB7 LLGLLVLLAGVCVFVLFQIEASGPAIAC-QYFTLYYAFYVAVLPTMSLACLAGTAIHGLE .::::....:. ::.......:: . : ...::.: .. : .:. :.:. :. .. NP_835 VLGLLLFVVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIYRFD 300 310 320 330 340 350 410 420 430 440 450 460 pF1KB7 ERELDTVKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQ .: .: :::::.:::.:::::::::..:.:.::::.:: :..:: : :...::.: : NP_835 RRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLAGLNLTHALLMIAQ 360 370 380 390 400 410 470 480 490 500 pF1KB7 HIAQNLFIIEGLHRRPLWETVPEGLAGKQE----------------AEPPRRGSLLELGQ : ::.::::.::: : :.. :. : :: : :. . NP_835 HTFQNMFIIESLHRGPPGAE-PHSTHPKEPCQDLTFTNLDALHTLSACPPNPG-LVSPSP 420 430 440 450 460 470 510 520 530 540 550 560 pF1KB7 GLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGY . :: ..: . : . .:.:. ::.:::::.:::. ::.::::: .:.: : .: ::::: NP_835 SDQREAVAIV-STPRSQWRRQCLKDISLFLLLCNVILWIMPAFGARPHFSNTVEVDFYGY 480 490 500 510 520 530 570 580 590 pF1KB7 QIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA ..: .:::. ::.:.:::::.:..:.:::. NP_835 SLWAVIVNICLPFGIFYRMHAVSSLLEVYVLS 540 550 560 >>NP_819056 (OMIM: 607806) otopetrin-1 [Homo sapiens] (612 aa) initn: 926 init1: 297 opt: 297 Z-score: 337.3 bits: 72.5 E(85289): 4.7e-12 Smith-Waterman score: 960; 32.1% identity (59.9% similar) in 611 aa overlap (36-593:3-609) 10 20 30 40 50 60 pF1KB7 RAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAATRPRQ :. . :.:. ..:.. :: : . NP_819 MLEGLGSPASPRAAASASVAGSSGPAACSPPS 10 20 30 70 80 90 100 110 120 pF1KB7 KSWLVRHFSLLLRRD--RQA--QKAGQLFSGLLALNVVFLGGAFIC-SMIFNKVAVTLGD .: : :: : . :: ....:. .: .::..: .. . . ..:. .: NP_819 SSAPRSPESPAPRRGGVRASVPQKLAEMLSSQYGL-IVFVAGLLLLLAWAVHAAGVSKSD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB7 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR . .:..: .:.:::.:.::. .. . . .: ::: :.:::..::. : :. .. NP_819 LLCFLTALMLLQLLWMLWYVGRSSAHRRLFRLKDTHAGAGWLRGSITLFAVITVILGCLK 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB7 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL .:: .. .: : . :: : . : .:.. :: : :: .. .. : :.. .. ::: NP_819 IGYFIGFSECLSATEGVFPVTHSVHTLLQVYFLWGHAKDIIQSFKTLERFGVIHSVFTNL 160 170 180 190 200 210 250 260 270 280 290 pF1KB7 LLWVLAVTNDSMHREIEAE-----LGIL-MEKSTGNETNTCLCLNATACEAFRRGFLMLY :::. .: :.: :. : . ::. . ..: : : : : :. .:. .:: NP_819 LLWANGVLNESKHQLNEHKERLITLGFGNITTVLDDHTPQCNCTPPTLCTAISHGIYYLY 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB7 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV ::. :: .. ..:.:.:::.::.: :. : :. :.. : .::: :: : . : NP_819 PFNIEYQILASTMLYVLWKNIGRKVDSHQ--HQKMQ-FKSDGVMVGAVLGLTVLAATIAV 280 290 300 310 320 360 370 380 390 400 410 pF1KB7 FVLFQIEASGPAIACQY-FTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRS :.. :. . . . ..: . ...: :. : ::: :. ..:. :: :::.:. NP_819 VVVYLIHIGRSKTKSESALIMFYLYAITLLMLMGAAGLAGIRIYRIDEKSLDESKNPARK 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB7 LDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLH :: ::.:.: :. :.. ::.::. . : . : ::.: :... :::::.:..: NP_819 LDSDLLVGTASGSWLISWGSILAILCAEGHPRYTWYNLPYSILAIVEKYIQNLFIFESIH 390 400 410 420 430 440 480 490 500 510 pF1KB7 RRP--LWE--------TVPEGLAGKQEAEPPRRGSLLE----LGQGLQRASLAYI-HSYS :.: : : :: .: . . :. :.. . :. . :. . . : NP_819 REPEKLSEDIQTLRVVTVCNGNTMPLASSCPKSGGVARDVAPQGKDMPPAANGNVCMRES 450 460 470 480 490 500 520 530 540 550 pF1KB7 H---------LNW-----------------KRRALKEISLFLILCNITLWMMPAFGIHPE : .: ::..:..:. ::.::::.::. :::: .:: NP_819 HDKEEEKQEESSWGGSPSPVRLPRFLQGNAKRKVLRNIAAFLFLCNISLWIPPAFGCRPE 510 520 530 540 550 560 560 570 580 590 pF1KB7 FENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA ..::::. .:.. :. .::...:...:::::....: ::: NP_819 YDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI 570 580 590 600 610 596 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:18:17 2016 done: Fri Nov 4 06:18:18 2016 Total Scan time: 10.260 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]