FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7248, 534 aa 1>>>pF1KB7248 534 - 534 aa - 534 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7783+/-0.000374; mu= 22.1294+/- 0.023 mean_var=78.5682+/-15.128, 0's: 0 Z-trim(114.1): 109 B-trim: 16 in 1/56 Lambda= 0.144694 statistics sampled from 23598 (23736) to 23598 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.278), width: 16 Scan time: 9.080 The best scores are: opt bits E(85289) NP_079106 (OMIM: 610472) lysophosphatidylcholine a ( 534) 3558 752.6 6.6e-217 XP_011512434 (OMIM: 610472) PREDICTED: lysophospha ( 571) 3260 690.5 3.7e-198 XP_011512436 (OMIM: 610472) PREDICTED: lysophospha ( 493) 3259 690.2 3.8e-198 XP_005248430 (OMIM: 610472) PREDICTED: lysophospha ( 486) 3240 686.2 5.9e-197 XP_016865368 (OMIM: 610472) PREDICTED: lysophospha ( 293) 1853 396.5 6e-110 NP_060309 (OMIM: 612040) lysophosphatidylcholine a ( 544) 1526 328.5 3.3e-89 XP_016878865 (OMIM: 612040) PREDICTED: lysophospha ( 488) 1463 315.3 2.8e-85 NP_705841 (OMIM: 612039) lysophospholipid acyltran ( 524) 1107 241.0 6.8e-63 XP_006720517 (OMIM: 612039) PREDICTED: lysophospho ( 409) 1024 223.6 9.4e-58 XP_005256063 (OMIM: 612040) PREDICTED: lysophospha ( 330) 876 192.6 1.6e-48 XP_011521471 (OMIM: 612040) PREDICTED: lysophospha ( 274) 705 156.8 7.9e-38 XP_011519724 (OMIM: 612039) PREDICTED: lysophospho ( 356) 546 123.7 9.3e-28 XP_011530686 (OMIM: 610958) PREDICTED: glycerol-3- ( 356) 217 55.0 4.4e-07 XP_011530685 (OMIM: 610958) PREDICTED: glycerol-3- ( 356) 217 55.0 4.4e-07 XP_016864270 (OMIM: 610958) PREDICTED: glycerol-3- ( 434) 217 55.1 5e-07 NP_001243351 (OMIM: 610958) glycerol-3-phosphate a ( 434) 217 55.1 5e-07 NP_001243350 (OMIM: 610958) glycerol-3-phosphate a ( 434) 217 55.1 5e-07 NP_116106 (OMIM: 610958) glycerol-3-phosphate acyl ( 434) 217 55.1 5e-07 XP_016864269 (OMIM: 610958) PREDICTED: glycerol-3- ( 526) 217 55.2 5.8e-07 XP_016868532 (OMIM: 608143) PREDICTED: glycerol-3- ( 248) 213 54.0 6.1e-07 XP_011542696 (OMIM: 608143) PREDICTED: glycerol-3- ( 456) 213 54.3 9.3e-07 XP_011542694 (OMIM: 608143) PREDICTED: glycerol-3- ( 456) 213 54.3 9.3e-07 XP_011542695 (OMIM: 608143) PREDICTED: glycerol-3- ( 456) 213 54.3 9.3e-07 NP_848934 (OMIM: 608143) glycerol-3-phosphate acyl ( 456) 213 54.3 9.3e-07 XP_016868531 (OMIM: 608143) PREDICTED: glycerol-3- ( 456) 213 54.3 9.3e-07 NP_001171708 (OMIM: 606572) NADPH oxidase 5 isofor ( 737) 194 50.6 2e-05 NP_001171709 (OMIM: 606572) NADPH oxidase 5 isofor ( 730) 192 50.1 2.7e-05 NP_000936 (OMIM: 601302) calcineurin subunit B typ ( 170) 174 45.7 0.00013 NP_671709 (OMIM: 613821) calcineurin subunit B typ ( 173) 170 44.9 0.00024 NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 147 40.1 0.0064 >>NP_079106 (OMIM: 610472) lysophosphatidylcholine acylt (534 aa) initn: 3558 init1: 3558 opt: 3558 Z-score: 4015.2 bits: 752.6 E(85289): 6.6e-217 Smith-Waterman score: 3558; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534) 10 20 30 40 50 60 pF1KB7 MRLRGCGPRAAPASSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MRLRGCGPRAAPASSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 AAAMMLLAWPLALVASLGSAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 AAAMMLLAWPLALVASLGSAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 QALPTEAAILTLAPHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 QALPTEAAILTLAPHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 DSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 DSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 KLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 ALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERAR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 MKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB7 IQLAFKMYGAQEDGSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 IQLAFKMYGAQEDGSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFA 430 440 450 460 470 480 490 500 510 520 530 pF1KB7 EMYPAFAEEYLYPDQTHFESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 EMYPAFAEEYLYPDQTHFESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD 490 500 510 520 530 >>XP_011512434 (OMIM: 610472) PREDICTED: lysophosphatidy (571 aa) initn: 3260 init1: 3260 opt: 3260 Z-score: 3678.6 bits: 690.5 E(85289): 3.7e-198 Smith-Waterman score: 3260; 99.8% identity (100.0% similar) in 491 aa overlap (44-534:81-571) 20 30 40 50 60 70 pF1KB7 SSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLVAAAMMLLAWPLAL :.:::::::::::::::::::::::::::: XP_011 VPVSLGQCWSVLVSLGQRRSALVSLGQPWSASVALMTLTLFPVRLLVAAAMMLLAWPLAL 60 70 80 90 100 110 80 90 100 110 120 130 pF1KB7 VASLGSAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VASLGSAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLA 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB7 PHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRR 180 190 200 210 220 230 200 210 220 230 240 250 pF1KB7 AQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPG 240 250 260 270 280 290 260 270 280 290 300 310 pF1KB7 ALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFED 300 310 320 330 340 350 320 330 340 350 360 370 pF1KB7 CQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFA 360 370 380 390 400 410 380 390 400 410 420 430 pF1KB7 ASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQED 420 430 440 450 460 470 440 450 460 470 480 490 pF1KB7 GSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYP 480 490 500 510 520 530 500 510 520 530 pF1KB7 DQTHFESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD ::::::::::::::::::::::::::::::::::::::::: XP_011 DQTHFESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD 540 550 560 570 >>XP_011512436 (OMIM: 610472) PREDICTED: lysophosphatidy (493 aa) initn: 3259 init1: 3259 opt: 3259 Z-score: 3678.3 bits: 690.2 E(85289): 3.8e-198 Smith-Waterman score: 3259; 99.8% identity (99.8% similar) in 491 aa overlap (44-534:3-493) 20 30 40 50 60 70 pF1KB7 SSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLVAAAMMLLAWPLAL : :::::::::::::::::::::::::::: XP_011 MAAPVALMTLTLFPVRLLVAAAMMLLAWPLAL 10 20 30 80 90 100 110 120 130 pF1KB7 VASLGSAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VASLGSAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB7 PHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRR 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB7 AQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPG 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB7 ALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFED 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB7 CQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFA 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB7 ASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQED 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB7 GSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYP 400 410 420 430 440 450 500 510 520 530 pF1KB7 DQTHFESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD ::::::::::::::::::::::::::::::::::::::::: XP_011 DQTHFESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD 460 470 480 490 >>XP_005248430 (OMIM: 610472) PREDICTED: lysophosphatidy (486 aa) initn: 3240 init1: 3240 opt: 3240 Z-score: 3656.9 bits: 686.2 E(85289): 5.9e-197 Smith-Waterman score: 3240; 100.0% identity (100.0% similar) in 486 aa overlap (49-534:1-486) 20 30 40 50 60 70 pF1KB7 SDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLVAAAMMLLAWPLALVASLG :::::::::::::::::::::::::::::: XP_005 MTLTLFPVRLLVAAAMMLLAWPLALVASLG 10 20 30 80 90 100 110 120 130 pF1KB7 SAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLAPHSSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLAPHSSY 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB7 FDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRRAQSNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRRAQSNG 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB7 KWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPGALEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPGALEIL 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB7 WLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFEDCQLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFEDCQLAL 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB7 AEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFAASLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFAASLEV 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB7 PVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQEDGSVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQEDGSVGE 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB7 GDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYPDQTHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYPDQTHF 400 410 420 430 440 450 500 510 520 530 pF1KB7 ESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD :::::::::::::::::::::::::::::::::::: XP_005 ESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD 460 470 480 >>XP_016865368 (OMIM: 610472) PREDICTED: lysophosphatidy (293 aa) initn: 1851 init1: 1851 opt: 1853 Z-score: 2094.9 bits: 396.5 E(85289): 6e-110 Smith-Waterman score: 1853; 96.9% identity (97.6% similar) in 291 aa overlap (245-534:3-293) 220 230 240 250 260 270 pF1KB7 TCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPGA-LEILWLTLCQFHNQVEIEF . : .: ::::::::::::::::::: XP_016 MWVRWCFQVKVLRLEILWLTLCQFHNQVEIEF 10 20 30 280 290 300 310 320 330 pF1KB7 LPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFEDCQLALAEGQLRLPADTCLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFEDCQLALAEGQLRLPADTCLLE 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB7 FARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDE 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB7 SGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQEDGSVGEGDLSCILKTALGVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQEDGSVGEGDLSCILKTALGVAE 160 170 180 190 200 210 460 470 480 490 500 510 pF1KB7 LTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYPDQTHFESCAETSPAPIPNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYPDQTHFESCAETSPAPIPNGF 220 230 240 250 260 270 520 530 pF1KB7 CADFSPENSDAGRKPVRKKLD ::::::::::::::::::::: XP_016 CADFSPENSDAGRKPVRKKLD 280 290 >>NP_060309 (OMIM: 612040) lysophosphatidylcholine acylt (544 aa) initn: 1353 init1: 1353 opt: 1526 Z-score: 1722.6 bits: 328.5 E(85289): 3.3e-89 Smith-Waterman score: 1526; 44.6% identity (75.2% similar) in 509 aa overlap (21-523:33-535) 10 20 30 40 50 pF1KB7 MRLRGCGPRAAPASSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMT : .. :: ::::.. .... ...:..:. NP_060 RCAQAAEVAATVPGAGVGNVGLRPPMVPRQASFFPPPVPNPFVQQTQIGSARRVQIVLLG 10 20 30 40 50 60 60 70 80 90 100 pF1KB7 LTLFPVRLLVAAAMMLLAWPLALVASLGSAEKEPEQPPALWR-KVVDFLLKAIMRTMWFA . :.:.:.:..: ..:::::.: .... :: .: . :: :... :: . :.:.:. NP_060 IILLPIRVLLVALILLLAWPFAAISTVCCPEKLT-HPITGWRRKITQTALKFLGRAMFFS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 GGFHRVAVKGRQALPTEAAILTLAPHSSYFDAIP-VTMTMSSIVMKAESRDIPIWGTLIQ :: :::::. : : :: ... ::::..::.: :. . :.: . :. ..:. : :.. NP_060 MGFI-VAVKGKIASPLEAPVFVAAPHSTFFDGIACVVAGLPSMVSRNENAQVPLIGRLLR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 YIRPVFVSRSDQDSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPG ..::.::: : :::..:..:: .:. :.:.::::..:::::::::.::::::::::::: NP_060 AVQPVLVSRVDPDSRKNTINEIIKRTTSGGEWPQILVFPEGTCTNRSCLITFKPGAFIPG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 APVQPVVLRYPNKLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPA .:::::.:::::::::.:::::: ... ::.::. ..::.::.:: :..::: .:. NP_060 VPVQPVLLRYPNKLDTVTWTWQGYTFIQLCMLTFCQLFTKVEVEFMPVQVPNDEEKNDPV 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 LYASNVRRVMAEALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKL :.:..:: .::::::. :::.:.:::.: .. ::: :: .. :.::... : : : . . NP_060 LFANKVRNLMAEALGIPVTDHTYEDCRLMISAGQLTLPMEAGLVEFTKISRKLKLDWDGV 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB7 EKDLDRYSERARMKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVAL .: ::.:. : . : .::: ::: :..::::.:...:.:::.. .: .:.:: :..: NP_060 RKHLDEYASIASSSKGGRIGIEEFAKYLKLPVSDVLRQLFALFDRNHDGSIDFREYVIGL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB7 SVVCRPARTLDTIQLAFKMYGAQEDGSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEK .:.: :. : . ::.:::.. ..::: . : ..: ::...::: .: :. ::. : : . NP_060 AVLCNPSNTEEIIQVAFKLFDVDEDGYITEEEFSTILQASLGVPDLDVSGLFKEIAQGD- 430 440 450 460 470 470 480 490 500 510 520 pF1KB7 GKITFADFHRFAEMYPAFAEEYLYPDQTHFESCAETS-PAPI---PNGFCADFSPENSDA .:.. .:. :: .: .:. .. ...: : : . :. :::. . NP_060 -SISYEEFKSFALKHPEYAK--IFTTYLDLQTCHVFSLPKEVQTTPSTASNKVSPEKHEE 480 490 500 510 520 530 530 pF1KB7 GRKPVRKKLD NP_060 STSDKKDD 540 >>XP_016878865 (OMIM: 612040) PREDICTED: lysophosphatidy (488 aa) initn: 1290 init1: 1290 opt: 1463 Z-score: 1652.2 bits: 315.3 E(85289): 2.8e-85 Smith-Waterman score: 1463; 45.2% identity (75.2% similar) in 484 aa overlap (46-523:2-479) 20 30 40 50 60 70 pF1KB7 AGASDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLVAAAMMLLAWPLALVA ..:. . :.:.:.:..: ..:::::.: .. XP_016 MIVLLGIILLPIRVLLVALILLLAWPFAAIS 10 20 30 80 90 100 110 120 130 pF1KB7 SLGSAEKEPEQPPALWR-KVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLAP .. :: .: . :: :... :: . :.:.:. :: :::::. : : :: ... :: XP_016 TVCCPEKLT-HPITGWRRKITQTALKFLGRAMFFSMGFI-VAVKGKIASPLEAPVFVAAP 40 50 60 70 80 140 150 160 170 180 190 pF1KB7 HSSYFDAIP-VTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRR ::..::.: :. . :.: . :. ..:. : :.. ..::.::: : :::..:..:: .: XP_016 HSTFFDGIACVVAGLPSMVSRNENAQVPLIGRLLRAVQPVLVSRVDPDSRKNTINEIIKR 90 100 110 120 130 140 200 210 220 230 240 250 pF1KB7 AQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPG . :.:.::::..:::::::::.:::::::::::::.:::::.:::::::::.:::::: XP_016 TTSGGEWPQILVFPEGTCTNRSCLITFKPGAFIPGVPVQPVLLRYPNKLDTVTWTWQGYT 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB7 ALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFED ... ::.::. ..::.::.:: :..::: .:.:.:..:: .::::::. :::.:.:: XP_016 FIQLCMLTFCQLFTKVEVEFMPVQVPNDEEKNDPVLFANKVRNLMAEALGIPVTDHTYED 210 220 230 240 250 260 320 330 340 350 360 370 pF1KB7 CQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFA :.: .. ::: :: .. :.::... : : : . ..: ::.:. : . : .::: ::: XP_016 CRLMISAGQLTLPMEAGLVEFTKISRKLKLDWDGVRKHLDEYASIASSSKGGRIGIEEFA 270 280 290 300 310 320 380 390 400 410 420 430 pF1KB7 ASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQED :..::::.:...:.:::.. .: .:.:: :..:.:.: :. : . ::.:::.. ..:: XP_016 KYLKLPVSDVLRQLFALFDRNHDGSIDFREYVIGLAVLCNPSNTEEIIQVAFKLFDVDED 330 340 350 360 370 380 440 450 460 470 480 490 pF1KB7 GSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYP : . : ..: ::...::: .: :. ::. : : .. :.. .:. :: .: .:. .. XP_016 GYITEEEFSTILQASLGVPDLDVSGLFKEIAQGDS--ISYEEFKSFALKHPEYAK--IFT 390 400 410 420 430 440 500 510 520 530 pF1KB7 DQTHFESCAETS-PAPI---PNGFCADFSPENSDAGRKPVRKKLD ...: : : . :. :::. . XP_016 TYLDLQTCHVFSLPKEVQTTPSTASNKVSPEKHEESTSDKKDD 450 460 470 480 >>NP_705841 (OMIM: 612039) lysophospholipid acyltransfer (524 aa) initn: 1068 init1: 726 opt: 1107 Z-score: 1250.1 bits: 241.0 E(85289): 6.8e-63 Smith-Waterman score: 1107; 37.6% identity (68.6% similar) in 500 aa overlap (26-510:18-505) 10 20 30 40 50 pF1KB7 MRLRGCGPRAAPASSAGASDARLLAPPGR-NPFVHELRLSALQKAQVALMTLTLFPVRLL ::. :::::::.:: ::... :. : :.:.: NP_705 MSQGSPGDWAPLDPTPGPPASPNPFVHELHLSRLQRVKFCLLGALLAPIRVL 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 VAAAMMLLAWPLALVASLGSAEKEPEQPPALWRKVV--DFLLKAIMRTMWFAGGFHRVAV .: ...: ::.: . : .:.. ..: . :::.: . .: .. : ..: :: :. : NP_705 LAFIVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVL-GLSRLLFFLLGFLRIRV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 KGRQALPTEAAILTLAPHSSYFDAIPVTMT---MSSIVMKAESRDIPIWGTLIQYIRPVF .:..: .: .:. ::::..:: :... . ..: .::. ..:. :.:... . .. NP_705 RGQRASRLQAPVLVAAPHSTFFD--PIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAIL 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 VSRSDQDSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPV ::: : :::..:::..::: :.:::::...::::::.:. :. ::::::: :.::::: NP_705 VSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPV 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 VLRYPNKLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNV ..::::.::: .:.:.:::.:..:::: : . :..:::::: :: ::.:.:.:::.:: NP_705 LIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYANNV 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 RRVMAEALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDR .::::.:::. .:. : ... :.:.. . : :.....: ::. . : NP_705 QRVMAQALGIPATECEFVGSLPVIVVGRLKVALEPQLWELGKVLRKAGLSAGYV--DAGA 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 YSERARMKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRP :.:: . : ::: .:.. . . :. :... .: ::.:. ..::... NP_705 EPGRSRMISQE-----EFARQLQLSDPQTVAGAFGYFQQDTKGLVDFRDVALALAAL-DG 350 360 370 380 390 400 420 430 440 450 460 pF1KB7 ARTLDTI-QLAFKMYGA-QEDGS---VGEGDLSCILKTALGVAELTVTDLFRAIDQEEKG .:.:. . .:::.... : .: . . .: ::. :: . ..: : . : .. NP_705 GRSLEELTRLAFELFAEEQAEGPNRLLYKDGFSTILHLLLGSPHPAATALHAELCQAGSS 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB7 K-ITFADFHRFAEMYPAFAE---EYLYPDQTHFESCAETSPAPIPNGFCADFSPENSDAG . ... .:. :. : ... :: : .: .. ..: : : NP_705 QGLSLCQFQNFSLHDPLYGKLFSTYLRPPHTS-RGTSQTPNASSPGNPTALANGTVQAPK 470 480 490 500 510 520 530 pF1KB7 RKPVRKKLD NP_705 QKGD >>XP_006720517 (OMIM: 612039) PREDICTED: lysophospholipi (409 aa) initn: 997 init1: 726 opt: 1024 Z-score: 1157.8 bits: 223.6 E(85289): 9.4e-58 Smith-Waterman score: 1024; 41.9% identity (71.9% similar) in 377 aa overlap (26-396:18-384) 10 20 30 40 50 pF1KB7 MRLRGCGPRAAPASSAGASDARLLAPPGR-NPFVHELRLSALQKAQVALMTLTLFPVRLL ::. :::::::.:: ::... :. : :.:.: XP_006 MSQGSPGDWAPLDPTPGPPASPNPFVHELHLSRLQRVKFCLLGALLAPIRVL 10 20 30 40 50 60 70 80 90 100 110 pF1KB7 VAAAMMLLAWPLALVASLGSAEKEPEQPPALWRKVV--DFLLKAIMRTMWFAGGFHRVAV .: ...: ::.: . : .:.. ..: . :::.: . .: .. : ..: :: :. : XP_006 LAFIVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVL-GLSRLLFFLLGFLRIRV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB7 KGRQALPTEAAILTLAPHSSYFDAIPVTMT---MSSIVMKAESRDIPIWGTLIQYIRPVF .:..: .: .:. ::::..:: :... . ..: .::. ..:. :.:... . .. XP_006 RGQRASRLQAPVLVAAPHSTFFD--PIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAIL 120 130 140 150 160 180 190 200 210 220 230 pF1KB7 VSRSDQDSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPV ::: : :::..:::..::: :.:::::...::::::.:. :. ::::::: :.::::: XP_006 VSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPV 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB7 VLRYPNKLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNV ..::::.::: .:.:.:::.:..:::: : . :..:::::: :: ::.:.:.:::.:: XP_006 LIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYANNV 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB7 RRVMAEALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDR .::::.:::. .:. : ... :.:.. . : :.....: ::. . : XP_006 QRVMAQALGIPATECEFVGSLPVIVVGRLKVALEPQLWELGKVLRKAGLSAGYV--DAGA 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB7 YSERARMKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRP :.:: :. ::: .:.. . . :. :....: XP_006 EPGRSRM-----ISQEEFARQLQLSDPQTVAGAFGYFQQASSALKSNVIIMRRNKGEIIM 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB7 ARTLDTIQLAFKMYGAQEDGSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFA XP_006 VPRSFLI >>XP_005256063 (OMIM: 612040) PREDICTED: lysophosphatidy (330 aa) initn: 842 init1: 742 opt: 876 Z-score: 992.0 bits: 192.6 E(85289): 1.6e-48 Smith-Waterman score: 876; 48.4% identity (79.7% similar) in 256 aa overlap (21-274:33-286) 10 20 30 40 50 pF1KB7 MRLRGCGPRAAPASSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMT : .. :: ::::.. .... ...:..:. XP_005 RCAQAAEVAATVPGAGVGNVGLRPPMVPRQASFFPPPVPNPFVQQTQIGSARRVQIVLLG 10 20 30 40 50 60 60 70 80 90 100 pF1KB7 LTLFPVRLLVAAAMMLLAWPLALVASLGSAEKEPEQPPALWR-KVVDFLLKAIMRTMWFA . :.:.:.:..: ..:::::.: .... :: .: . :: :... :: . :.:.:. XP_005 IILLPIRVLLVALILLLAWPFAAISTVCCPEKLT-HPITGWRRKITQTALKFLGRAMFFS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB7 GGFHRVAVKGRQALPTEAAILTLAPHSSYFDAIP-VTMTMSSIVMKAESRDIPIWGTLIQ :: :::::. : : :: ... ::::..::.: :. . :.: . :. ..:. : :.. XP_005 MGFI-VAVKGKIASPLEAPVFVAAPHSTFFDGIACVVAGLPSMVSRNENAQVPLIGRLLR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB7 YIRPVFVSRSDQDSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPG ..::.::: : :::..:..:: .:. :.:.::::..:::::::::.::::::::::::: XP_005 AVQPVLVSRVDPDSRKNTINEIIKRTTSGGEWPQILVFPEGTCTNRSCLITFKPGAFIPG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB7 APVQPVVLRYPNKLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPA .:::::.:::::::::.:::::: ... ::.::. ..::.:.. XP_005 VPVQPVLLRYPNKLDTVTWTWQGYTFIQLCMLTFCQLFTKVEVEMFLFFWEGSSKHCLKI 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB7 LYASNVRRVMAEALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKL XP_005 SSFFCIFSLRRFKRRITQRTRTAHLLRLSF 310 320 330 534 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:18:57 2016 done: Fri Nov 4 06:18:58 2016 Total Scan time: 9.080 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]