FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7249, 123 aa 1>>>pF1KB7249 123 - 123 aa - 123 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7596+/-0.000399; mu= 12.7529+/- 0.025 mean_var=54.9850+/-11.477, 0's: 0 Z-trim(113.1): 108 B-trim: 1166 in 2/53 Lambda= 0.172963 statistics sampled from 22087 (22239) to 22087 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.261), width: 16 Scan time: 4.720 The best scores are: opt bits E(85289) NP_996802 (OMIM: 612405) ADP-ribosylation factor-l ( 123) 793 205.6 1.6e-53 XP_006714099 (OMIM: 612405) PREDICTED: ADP-ribosyl ( 123) 793 205.6 1.6e-53 XP_005265777 (OMIM: 612405) PREDICTED: ADP-ribosyl ( 123) 793 205.6 1.6e-53 XP_005265776 (OMIM: 612405) PREDICTED: ADP-ribosyl ( 265) 793 205.8 3e-53 NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 201 58.0 7.1e-09 NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 201 58.0 7.1e-09 NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 201 58.0 7.1e-09 NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 201 58.0 7.1e-09 NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 199 57.5 9.3e-09 XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 199 57.5 9.3e-09 NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 198 57.3 1.2e-08 NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 198 57.3 1.2e-08 NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 194 56.3 2.1e-08 NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 188 54.7 4.9e-08 NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 189 55.0 5.3e-08 NP_001254475 (OMIM: 604699) ADP-ribosylation facto ( 154) 188 54.7 5.4e-08 NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 188 54.8 6.2e-08 NP_003215 (OMIM: 604699) ADP-ribosylation factor-r ( 201) 188 54.8 6.7e-08 XP_011526784 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 188 54.8 6.7e-08 XP_011526785 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 188 54.8 6.7e-08 XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 188 54.8 6.7e-08 NP_001254477 (OMIM: 604699) ADP-ribosylation facto ( 201) 188 54.8 6.7e-08 NP_001254476 (OMIM: 604699) ADP-ribosylation facto ( 201) 188 54.8 6.7e-08 NP_001128230 (OMIM: 604699) ADP-ribosylation facto ( 173) 187 54.5 7.1e-08 NP_001254478 (OMIM: 604699) ADP-ribosylation facto ( 173) 187 54.5 7.1e-08 NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 182 53.3 1.9e-07 XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 182 53.3 1.9e-07 XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 181 53.0 2.2e-07 NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 181 53.0 2.2e-07 NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 180 52.8 2.5e-07 NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 180 52.8 2.5e-07 NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 180 52.8 2.5e-07 XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 180 52.8 2.5e-07 NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 180 52.8 2.5e-07 NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 180 52.8 2.5e-07 XP_011510837 (OMIM: 608922,612291) PREDICTED: ADP- ( 403) 182 53.5 3.4e-07 NP_001308257 (OMIM: 608922,612291) ADP-ribosylatio ( 413) 182 53.5 3.4e-07 XP_011510836 (OMIM: 608922,612291) PREDICTED: ADP- ( 413) 182 53.5 3.4e-07 XP_006713595 (OMIM: 608922,612291) PREDICTED: ADP- ( 413) 182 53.5 3.4e-07 XP_011510835 (OMIM: 608922,612291) PREDICTED: ADP- ( 416) 182 53.5 3.5e-07 XP_011510834 (OMIM: 608922,612291) PREDICTED: ADP- ( 416) 182 53.5 3.5e-07 NP_878899 (OMIM: 608922,612291) ADP-ribosylation f ( 428) 182 53.5 3.5e-07 NP_001167621 (OMIM: 608922,612291) ADP-ribosylatio ( 428) 182 53.5 3.5e-07 NP_620150 (OMIM: 616597) ADP-ribosylation factor-l ( 186) 178 52.3 3.6e-07 NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 177 52.0 4.3e-07 XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 174 51.2 5.7e-07 NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 174 51.3 6.9e-07 XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 174 51.5 1.3e-06 NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 170 50.3 1.4e-06 XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 174 51.6 1.8e-06 >>NP_996802 (OMIM: 612405) ADP-ribosylation factor-like (123 aa) initn: 793 init1: 793 opt: 793 Z-score: 1081.8 bits: 205.6 E(85289): 1.6e-53 Smith-Waterman score: 793; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDSADHSRLPEAKKYLHQLIAANPVLPLVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDSADHSRLPEAKKYLHQLIAANPVLPLVVF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ANKQDLEAAYHITDIHEALALSEVGNDRKMFLFGTYLTKNGSEIPSTMQDAKDLIAQLAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 ANKQDLEAAYHITDIHEALALSEVGNDRKMFLFGTYLTKNGSEIPSTMQDAKDLIAQLAA 70 80 90 100 110 120 pF1KB7 DVQ ::: NP_996 DVQ >>XP_006714099 (OMIM: 612405) PREDICTED: ADP-ribosylatio (123 aa) initn: 793 init1: 793 opt: 793 Z-score: 1081.8 bits: 205.6 E(85289): 1.6e-53 Smith-Waterman score: 793; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDSADHSRLPEAKKYLHQLIAANPVLPLVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDSADHSRLPEAKKYLHQLIAANPVLPLVVF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ANKQDLEAAYHITDIHEALALSEVGNDRKMFLFGTYLTKNGSEIPSTMQDAKDLIAQLAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ANKQDLEAAYHITDIHEALALSEVGNDRKMFLFGTYLTKNGSEIPSTMQDAKDLIAQLAA 70 80 90 100 110 120 pF1KB7 DVQ ::: XP_006 DVQ >>XP_005265777 (OMIM: 612405) PREDICTED: ADP-ribosylatio (123 aa) initn: 793 init1: 793 opt: 793 Z-score: 1081.8 bits: 205.6 E(85289): 1.6e-53 Smith-Waterman score: 793; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDSADHSRLPEAKKYLHQLIAANPVLPLVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDSADHSRLPEAKKYLHQLIAANPVLPLVVF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 ANKQDLEAAYHITDIHEALALSEVGNDRKMFLFGTYLTKNGSEIPSTMQDAKDLIAQLAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANKQDLEAAYHITDIHEALALSEVGNDRKMFLFGTYLTKNGSEIPSTMQDAKDLIAQLAA 70 80 90 100 110 120 pF1KB7 DVQ ::: XP_005 DVQ >>XP_005265776 (OMIM: 612405) PREDICTED: ADP-ribosylatio (265 aa) initn: 793 init1: 793 opt: 793 Z-score: 1076.9 bits: 205.8 E(85289): 3e-53 Smith-Waterman score: 793; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:143-265) 10 20 30 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVV :::::::::::::::::::::::::::::: XP_005 LHSLASNRVQHSVAPTQGFHAVCINTEDSQMEFLEIGGSKPFRSYWEMYLSKGLLLIFVV 120 130 140 150 160 170 40 50 60 70 80 90 pF1KB7 DSADHSRLPEAKKYLHQLIAANPVLPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSADHSRLPEAKKYLHQLIAANPVLPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKM 180 190 200 210 220 230 100 110 120 pF1KB7 FLFGTYLTKNGSEIPSTMQDAKDLIAQLAADVQ ::::::::::::::::::::::::::::::::: XP_005 FLFGTYLTKNGSEIPSTMQDAKDLIAQLAADVQ 240 250 260 >>NP_001032241 (OMIM: 604786) ADP-ribosylation factor-li (200 aa) initn: 165 init1: 111 opt: 201 Z-score: 280.3 bits: 58.0 E(85289): 7.1e-09 Smith-Waterman score: 201; 30.8% identity (63.2% similar) in 117 aa overlap (3-117:73-188) 10 20 30 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDS : ..::.. .: :. : ..::::: NP_001 NEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDS 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB7 ADHSRLPEAKKYLHQL--IAANPVLPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKM .: :. ::: ::.. :. : .:... ::::::. . ...:.. ::..:.... NP_001 VDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPW 110 120 130 140 150 160 100 110 120 pF1KB7 FLFGTYLTKNGSEIPSTMQDAKDLIAQLAADVQ : : . :. . .. .:.: . NP_001 HLQPT-CAIIGDGLKEGLEKLHDMIIKRRKMLRQQKKKR 170 180 190 200 >>NP_005729 (OMIM: 604786) ADP-ribosylation factor-like (200 aa) initn: 165 init1: 111 opt: 201 Z-score: 280.3 bits: 58.0 E(85289): 7.1e-09 Smith-Waterman score: 201; 30.8% identity (63.2% similar) in 117 aa overlap (3-117:73-188) 10 20 30 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDS : ..::.. .: :. : ..::::: NP_005 NEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDS 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB7 ADHSRLPEAKKYLHQL--IAANPVLPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKM .: :. ::: ::.. :. : .:... ::::::. . ...:.. ::..:.... NP_005 VDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPW 110 120 130 140 150 160 100 110 120 pF1KB7 FLFGTYLTKNGSEIPSTMQDAKDLIAQLAADVQ : : . :. . .. .:.: . NP_005 HLQPT-CAIIGDGLKEGLEKLHDMIIKRRKMLRQQKKKR 170 180 190 200 >>NP_997625 (OMIM: 604786) ADP-ribosylation factor-like (200 aa) initn: 165 init1: 111 opt: 201 Z-score: 280.3 bits: 58.0 E(85289): 7.1e-09 Smith-Waterman score: 201; 30.8% identity (63.2% similar) in 117 aa overlap (3-117:73-188) 10 20 30 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDS : ..::.. .: :. : ..::::: NP_997 NEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDS 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB7 ADHSRLPEAKKYLHQL--IAANPVLPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKM .: :. ::: ::.. :. : .:... ::::::. . ...:.. ::..:.... NP_997 VDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPW 110 120 130 140 150 160 100 110 120 pF1KB7 FLFGTYLTKNGSEIPSTMQDAKDLIAQLAADVQ : : . :. . .. .:.: . NP_997 HLQPT-CAIIGDGLKEGLEKLHDMIIKRRKMLRQQKKKR 170 180 190 200 >>NP_001182325 (OMIM: 604786) ADP-ribosylation factor-li (200 aa) initn: 165 init1: 111 opt: 201 Z-score: 280.3 bits: 58.0 E(85289): 7.1e-09 Smith-Waterman score: 201; 30.8% identity (63.2% similar) in 117 aa overlap (3-117:73-188) 10 20 30 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDS : ..::.. .: :. : ..::::: NP_001 NEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDS 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB7 ADHSRLPEAKKYLHQL--IAANPVLPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKM .: :. ::: ::.. :. : .:... ::::::. . ...:.. ::..:.... NP_001 VDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPW 110 120 130 140 150 160 100 110 120 pF1KB7 FLFGTYLTKNGSEIPSTMQDAKDLIAQLAADVQ : : . :. . .. .:.: . NP_001 HLQPT-CAIIGDGLKEGLEKLHDMIIKRRKMLRQQKKKR 170 180 190 200 >>NP_004302 (OMIM: 604695) ADP-ribosylation factor-like (182 aa) initn: 197 init1: 127 opt: 199 Z-score: 278.2 bits: 57.5 E(85289): 9.3e-09 Smith-Waterman score: 199; 38.4% identity (70.9% similar) in 86 aa overlap (5-88:67-151) 10 20 30 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDSAD .:::.. .: ::. :. . .::.:.:::: NP_004 LASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSAD 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB7 HSRLPEAKKYLHQLIAANPV--LPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKMFL ..:. :. . : .:. . . .:...::::::: .: ..: :.: : . :: NP_004 RKRFEETGQELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTI-RDRVWQI 100 110 120 130 140 150 100 110 120 pF1KB7 FGTYLTKNGSEIPSTMQDAKDLIAQLAADVQ NP_004 QSCSALTGEGVQDGMNWVCKNVNAKKK 160 170 180 >>XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosylatio (182 aa) initn: 197 init1: 127 opt: 199 Z-score: 278.2 bits: 57.5 E(85289): 9.3e-09 Smith-Waterman score: 199; 38.4% identity (70.9% similar) in 86 aa overlap (5-88:67-151) 10 20 30 pF1KB7 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVVDSAD .:::.. .: ::. :. . .::.:.:::: XP_016 LASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSAD 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB7 HSRLPEAKKYLHQLIAANPV--LPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKMFL ..:. :. . : .:. . . .:...::::::: .: ..: :.: : . :: XP_016 RKRFEETGQELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTI-RDRVWQI 100 110 120 130 140 150 100 110 120 pF1KB7 FGTYLTKNGSEIPSTMQDAKDLIAQLAADVQ XP_016 QSCSALTGEGVQDGMNWVCKNVNAKKK 160 170 180 123 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:20:16 2016 done: Fri Nov 4 06:20:17 2016 Total Scan time: 4.720 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]