FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB7262, 451 aa 1>>>pF1KB7262 451 - 451 aa - 451 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7513+/-0.000794; mu= 13.8239+/- 0.048 mean_var=154.0546+/-29.737, 0's: 0 Z-trim(115.4): 40 B-trim: 99 in 2/49 Lambda= 0.103332 statistics sampled from 15897 (15937) to 15897 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.49), width: 16 Scan time: 3.620 The best scores are: opt bits E(32554) CCDS8234.1 CHRDL2 gene_id:25884|Hs108|chr11 ( 451) 3335 508.5 5.8e-144 CCDS60893.1 CHRDL2 gene_id:25884|Hs108|chr11 ( 429) 2790 427.2 1.6e-119 CCDS14553.1 CHRDL1 gene_id:91851|Hs108|chrX ( 456) 1107 176.3 5.6e-44 CCDS48150.1 CHRDL1 gene_id:91851|Hs108|chrX ( 457) 1105 176.0 6.9e-44 CCDS48149.1 CHRDL1 gene_id:91851|Hs108|chrX ( 458) 1099 175.1 1.3e-43 CCDS48148.2 CHRDL1 gene_id:91851|Hs108|chrX ( 378) 578 97.4 2.7e-20 >>CCDS8234.1 CHRDL2 gene_id:25884|Hs108|chr11 (451 aa) initn: 3335 init1: 3335 opt: 3335 Z-score: 2698.1 bits: 508.5 E(32554): 5.8e-144 Smith-Waterman score: 3335; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB7 MVPEVRVLSSLLGLALLWFPLDSHARARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MVPEVRVLSSLLGLALLWFPLDSHARARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPSGLRAPPKSCQHNGTMYQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 CTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPSGLRAPPKSCQHNGTMYQH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 GEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEASE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 QSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KIVLKEKHKKACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KIVLKEKHKKACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 RHPEKVAGKCCKICPEDKADPGHSEISSTRCPKAPGRVLVHTSVSPSPDNLRRFALEHEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 RHPEKVAGKCCKICPEDKADPGHSEISSTRCPKAPGRVLVHTSVSPSPDNLRRFALEHEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SDLVEIYLWKLVKDEETEAQRGEVPGPRPHSQNLPLDSDQESQEARLPERGTALPTARWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SDLVEIYLWKLVKDEETEAQRGEVPGPRPHSQNLPLDSDQESQEARLPERGTALPTARWP 370 380 390 400 410 420 430 440 450 pF1KB7 PRRSLERLPSPDPGAEGHGQSRQSDQDITKT ::::::::::::::::::::::::::::::: CCDS82 PRRSLERLPSPDPGAEGHGQSRQSDQDITKT 430 440 450 >>CCDS60893.1 CHRDL2 gene_id:25884|Hs108|chr11 (429 aa) initn: 2790 init1: 2790 opt: 2790 Z-score: 2259.3 bits: 427.2 E(32554): 1.6e-119 Smith-Waterman score: 2790; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373) 10 20 30 40 50 60 pF1KB7 MVPEVRVLSSLLGLALLWFPLDSHARARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MVPEVRVLSSLLGLALLWFPLDSHARARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCLR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB7 CTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPSGLRAPPKSCQHNGTMYQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 CTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPSGLRAPPKSCQHNGTMYQH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB7 GEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEASE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB7 QSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB7 KIVLKEKHKKACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KIVLKEKHKKACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB7 RHPEKVAGKCCKICPEDKADPGHSEISSTRCPKAPGRVLVHTSVSPSPDNLRRFALEHEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RHPEKVAGKCCKICPEDKADPGHSEISSTRCPKAPGRVLVHTSVSPSPDNLRRFALEHEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB7 SDLVEIYLWKLVKDEETEAQRGEVPGPRPHSQNLPLDSDQESQEARLPERGTALPTARWP ::::::::::::: CCDS60 SDLVEIYLWKLVKGIFHLTQIKKVRKQDFQKEAQHFRLLAGPHEGHWNVFLAQTLELKVT 370 380 390 400 410 420 >>CCDS14553.1 CHRDL1 gene_id:91851|Hs108|chrX (456 aa) initn: 1003 init1: 626 opt: 1107 Z-score: 903.0 bits: 176.3 E(32554): 5.6e-44 Smith-Waterman score: 1107; 42.6% identity (68.3% similar) in 357 aa overlap (30-373:34-383) 10 20 30 40 50 pF1KB7 MVPEVRVLSSLLGLALLWFPLDSHARARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCL . .:.:. :.: :: ::::::: ::.::. CCDS14 KWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 RCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPSGLRAPPKSCQHNGTMYQ : :::...: : :..:: ::: .:: :. :::.: . : . .. :::..::: :: CCDS14 NCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 HGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEAS :::.: :. :: .: ::::. :::.::..:::: :::. : :. .:::::..:. .. CCDS14 HGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 EQSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIP--RHFR-----P . .. :. :.: . . . .:. : :. .. :: .: : : CCDS14 LSWEHSDG----DIFRQPANREARHS-YHRSHYDPPPSRQAGGLSRFPGARSHRGALMDS 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 KGAGSTTVKIVLKEKHK--KACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQ . :..: :.::...::: ..:: .:::::::: ::: .:::: . :.::::. .:.:. CCDS14 QQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECK 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 RVTCPTEYPCRHPEKVAGKCCKICPEDKAD--PGHS-EISSTRCPKAPGRVLVHTSV-SP .. ::..:::..:.:. :::::.:: :: ::.: . .. : . . :. :: CCDS14 KIHCPNRYPCKYPQKIDGKCCKVCPGKKAKELPGQSFDNKGYFCGEET--MPVYESVFME 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 SPDNLRRFALEHEASDLVEIYLWKLVKDEETEAQRGEVPGPRPHSQNLPLDSDQESQEAR . .. :..::: : ::...: . : CCDS14 DGETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQW 360 370 380 390 400 410 >>CCDS48150.1 CHRDL1 gene_id:91851|Hs108|chrX (457 aa) initn: 1003 init1: 626 opt: 1105 Z-score: 901.4 bits: 176.0 E(32554): 6.9e-44 Smith-Waterman score: 1105; 42.5% identity (68.2% similar) in 358 aa overlap (30-373:34-384) 10 20 30 40 50 pF1KB7 MVPEVRVLSSLLGLALLWFPLDSHARARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCL . .:.:. :.: :: ::::::: ::.::. CCDS48 KWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 RCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPSGLRAPPKSCQHNGTMYQ : :::...: : :..:: ::: .:: :. :::.: . : . .. :::..::: :: CCDS48 NCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 HGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEAS :::.: :. :: .: ::::. :::.::..:::: :::. : :. .:::::..:. .. CCDS48 HGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDGE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 EQSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIP--RHFR-----P . .. :. :.: . . . .:. : :. .. :: .: : : CCDS48 LSWEHSDG----DIFRQPANREARHS-YHRSHYDPPPSRQAGGLSRFPGARSHRGALMDS 190 200 210 220 230 240 250 260 270 280 290 pF1KB7 KGAGSTTVKIVLKEKHK--KACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQ . :..: :.::...::: ..:: .:::::::: ::: .:::: . :.::::. .:.:. CCDS48 QQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECK 240 250 260 270 280 290 300 310 320 330 340 pF1KB7 RVTCPTEYPCRHPEKVAGKCCKICPEDKAD---PGHS-EISSTRCPKAPGRVLVHTSV-S .. ::..:::..:.:. :::::.:: :: ::.: . .. : . . :. :: CCDS48 KIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEET--MPVYESVFM 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 PSPDNLRRFALEHEASDLVEIYLWKLVKDEETEAQRGEVPGPRPHSQNLPLDSDQESQEA . .. :..::: : ::...: . : CCDS48 EDGETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQ 360 370 380 390 400 410 >>CCDS48149.1 CHRDL1 gene_id:91851|Hs108|chrX (458 aa) initn: 1042 init1: 391 opt: 1099 Z-score: 896.5 bits: 175.1 E(32554): 1.3e-43 Smith-Waterman score: 1100; 42.6% identity (68.0% similar) in 359 aa overlap (30-373:34-385) 10 20 30 40 50 pF1KB7 MVPEVRVLSSLLGLALLWFPLDSHARARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCL . .:.:. :.: :: ::::::: ::.::. CCDS48 KWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 RCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPS-GLRAPPKSCQHNGTMY : :::...: : :..:: ::: .:: :. :::.: : : . .. :::..::: : CCDS48 NCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB7 QHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEA ::::.: :. :: .: ::::. :::.::..:::: :::. : :. .:::::..:. .. CCDS48 QHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDSCCRVCRGDG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB7 SEQSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIP--RHFR----- . .. :. :.: . . . .:. : :. .. :: .: : : CCDS48 ELSWEHSDG----DIFRQPANREARHS-YHRSHYDPPPSRQAGGLSRFPGARSHRGALMD 190 200 210 220 230 240 250 260 270 280 pF1KB7 PKGAGSTTVKIVLKEKHK--KACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDC . :..: :.::...::: ..:: .:::::::: ::: .:::: . :.::::. .:.: CCDS48 SQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQEC 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB7 QRVTCPTEYPCRHPEKVAGKCCKICPEDKAD---PGHS-EISSTRCPKAPGRVLVHTSV- ... ::..:::..:.:. :::::.:: :: ::.: . .. : . . :. :: CCDS48 KKIHCPNRYPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEET--MPVYESVF 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB7 SPSPDNLRRFALEHEASDLVEIYLWKLVKDEETEAQRGEVPGPRPHSQNLPLDSDQESQE . .. :..::: : ::...: . : CCDS48 MEDGETTRKIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLS 360 370 380 390 400 410 >>CCDS48148.2 CHRDL1 gene_id:91851|Hs108|chrX (378 aa) initn: 703 init1: 391 opt: 578 Z-score: 477.8 bits: 97.4 E(32554): 2.7e-20 Smith-Waterman score: 661; 33.0% identity (55.3% similar) in 351 aa overlap (30-373:34-305) 10 20 30 40 50 pF1KB7 MVPEVRVLSSLLGLALLWFPLDSHARARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCL . .:.:. :.: :: ::::::: ::.::. CCDS48 KWKMGGMKYIFSLLFFLLLEGGKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB7 RCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCVEPHTPSGLRAPPKSCQHNGTMYQ : :::...: : :..:: ::: .:: :. :::.: :. CCDS48 NCICSENGNVLCSRVRCPNVHCLSPVHIPHLCCPRC-----PGD---------------- 70 80 90 100 120 130 140 150 160 170 pF1KB7 HGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTCPEPGCPAPLPLPDSCCQACKDEAS ::. : ..:.:. CCDS48 -GELSWEH----------------SDGDIF------------------------------ 110 180 190 200 210 220 230 pF1KB7 EQSDEEDSVQSLHGVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTT .: .... .: : .. : . .: .: ::. . : : .. . :..: CCDS48 RQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRG--ALMD-------SQQASGTI 120 130 140 150 160 240 250 260 270 280 290 pF1KB7 VKIVLKEKHK--KACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTE :.::...::: ..:: .:::::::: ::: .:::: . :.::::. .:.:... ::.. CCDS48 VQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNR 170 180 190 200 210 220 300 310 320 330 340 350 pF1KB7 YPCRHPEKVAGKCCKICPEDKAD---PGHS-EISSTRCPKAPGRVLVHTSV-SPSPDNLR :::..:.:. :::::.:: :: ::.: . .. : . . :. :: . .. : CCDS48 YPCKYPQKIDGKCCKVCPGKKAKEELPGQSFDNKGYFCGEET--MPVYESVFMEDGETTR 230 240 250 260 270 280 360 370 380 390 400 410 pF1KB7 RFALEHEASDLVEIYLWKLVKDEETEAQRGEVPGPRPHSQNLPLDSDQESQEARLPERGT ..::: : ::...: . : CCDS48 KIALETERPPQVEVHVWTIRKGILQHFHIEKISKRMFEELPHFKLVTRTTLSQWKIFTEG 290 300 310 320 330 340 451 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 06:26:41 2016 done: Fri Nov 4 06:26:41 2016 Total Scan time: 3.620 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]